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신숭휘,진귀옥,최수미,김필녀,표민금,주수만,김종우,홍남두 한국병원약사회 1992 병원약사회지 Vol.9 No.1
This study was aimed to analyze the acute poisoning cases in Kyung Hee University Medical Center ER. The pertinent data were collected from available patients charts, and this study was conducted from 7/89 to 6/91. From the total number of 37396 ER admissions, 702 were due to acute poisonings, occupying 1.9% of total ER patient population. All data were categorized by sex, age, poisoning substance, motive and poisoning route. After this analysis, following conclusions were drawn : first, most of acute poisoning cases were in adults, and 30.6% of these adult cases were in age group of 20~29 years. Secondly, most common motive was accident(53.5%), followed by suicidal attempt(26.5%) ad others(20.0%). Regarding the route of poisoning, ingestion was 57.9% and other common routes were CO inhalation and bites. Finally, the causal agents were medication(31.9%), CO gas(20.5%), bites(13.5%) and agricultural agents(5.9%). There are many acute poisonings by our own social and environmental factors.
신숭휘,하미애,곽수란,송보완,김종우,홍남두 한국병원약사회 1994 병원약사회지 Vol.11 No.4
In drug dispensing with ATC(Automatic Tablet Counting & Sorting Machine), the composition of prescriptions may give an influence on the ATC operation ratio. So we made a research to solve the problem of ATC operation ratio influenced by the prescription's component in Sept. 1994, at the department of pharmacy in Kyung Hee University Medical Center. All of the prescriptions was classified and analyzed except pediatric department. As a result, total counts of prescriptions were 23,973, among these prescriptions 29.1% was possible dispensed by ATC, but only 25.1% was done by ATC. And ATC is usually using for the long term prescriptions. So if it is recalculated into the prescription days, the ATC operation ratio was 42.0%. The cause of including splitted tablets, was 3.6% in the case of including liquids, powders, external uses and was 20.3% which require more cassettes in ATC. In conclusion, to improve the operation ratio of ATC, below listed are required. First development of variable kinds of tablet doses, second is enlarging the counts of cassettes in ATC.
하미애,신숭휘,송보완,김종우,홍남두 한국병원약사회 1995 病院藥師會誌 Vol.12 No.4
Although original tablets are almost fit in weight variation test, in many cases, tablets are practically splitted for dose control in dispensing. These splitted tablets are considered secondary cause of weight variation. So, in this study tablets were classified into three groups by the average weight, first group was below 0.12g(A), second was more than 0.12g below 0.3g(B) and third was more than 0.3g(C). Each group consists of four kinds of tablet and weight variation after tablet splitting was calculated. As a result, average violation rate of weight variation test was 60% for A group, 42.5% for B group, 55% for C group. And the relation of hardness of tablet was the higher rate of weight variation. In conclusion, split of tablet for dose control in dispending was absolutely a cause of dose mistake. Especially drugs having side effect or toxic effect should be carefully when pharmacists split of tablet for dose control in dispending was absolutely a cause of dose mistake. Especially drugs having side effect or toxic effect should be carefully when pharmacists split tablets for dose control in dispensing.
자동 정제 포장기(ATC) 사용에 따른 정제 중량 변동에 대한 연구
홍혜정,이미경,신숭휘,주수만,김남재,송보완,김종우 한국병원약사회 1998 병원약사회지 Vol.15 No.4
While operating automatic tablet counter(ATC), there were filling error and filling time delay due to the breaking of tablets. This was presumed to happen mostly to uncoated tablet. This research was performed to show the adequate dosage form to operate ATC efficiently. As methods, error of stuck pills was analyzed by dosage form, distribution of dosage forms in ATC was examined in Korea and Japan. Stability was studied in terms of physical strength such as hardness and friability. The results show that 54% of stuck pills in the cassette of ATC during operation was uncoated tablet. The proportion of uncoated tablet, coated tablet, capsule in ATC was 67%, 34%, 19%, respectively in Korea, and was 9%, 64%, 26% respectively in Japan. The stability test of physical strength shows when the hardness were 1.5, 3.7, 6.6(㎏/cm2), the weight loss were 1.29%, 0.72%m 0.24% and when the friability 0.19%, 0.27%, 0.48%, the weight loss were 0.93%, 1.45%, 1.82%.