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손무현,박정규,황현식,김병호,정의달,최영식 고신대학교(의대) 고신대학교 의과대학 학술지 2013 고신대학교 의과대학 학술지 Vol.28 No.2
Addison’s disease is a rare disorder that causes fatigue, genral weakness, weight loss, pigmentation due to adrenal hypofunction and it’s underlying causes are various. We report a case of 42-year-old man with fatigue, generalized cutaneous pigmentation. Computed tomography showed bilateral adrenal enlargement, but no calcification. Adrenal tuberculosis was established by ultrasound-guided fine needle aspiration biopsy.
Recurrent thymic carcinoid tumor in familial isolated primary hyperparathyroidism
송정은,손무현,김가영,이다영,이정훈,김종호,손호상,이지현,전언주,정의달 영남대학교 의과대학 2014 Yeungnam University Journal of Medicine Vol.31 No.2
Familial isolated primary hyperparathyroidism(FIPH) is associated with multiple endocrine neoplasia type 1 (MEN1) syndrome, primary hyperparathyroidism accompanied by jaw-tumor syndrome, and familial hypocalciuric hypercalcemia. FIPH may be an early stage of MEN1 or an allelic variant of MEN1. Thymic carcinoid tumor is a rare tumor in MEN1 syndrome. Here, the authors report the case of a 40-year-old man diagnosed with recurrent thymic carcinoid tumor and FIPH. Both the patient and his elder sister had been previously diagnosed to have FIPH with a novel frameshift mutation in the MEN1 gene. Initially, the patient underwent thymectomy because of an incidental finding of a mediastinal mass in his chest X-ray, and had remained asymptomatic over the following 4 years. Pancreas computed tomography conducted to evaluate MEN1 syndrome revealed anterior and middle mediastinal masses, and resultantly, massive mass excision was performed. Histological findings disclosed atypical carcinoids with infiltrative margins. In view of the thymic carcinoid tumor relapse that occurred in this patient, the authors recommend that regular pancreas and pituitary imaging studies be conducted for FIPH associated with a MEN1 gene mutation.
PZT-고분자 3-3형 복합압전체 소자로 제작된 초음파 트랜스듀서의 펄스에코 응답특성
박정학,최헌일,손무현,사공건 한국전기전자재료학회 1996 電氣電子材料學會誌 Vol.9 No.10
The pulse-echo response of the piezoceramics PZT-polymer 3-3 type composite transducers with various PVA additions were investigated. The PZT powder was prepared by the molten salt synthesis method. The porous PZT specimens will be used as a filler to make 3-3 type comosite were prepared from a mixture of PZT and polyvinylalcohol(PVA) sphere by utilizing BURPS(Bumout Plastic Sphere) technique. It was shown that the transmitting and receiving sensitivity of 3-3 type piezoelectric composite transducers could be improved than that of solid PZT transducers. The reason is that 3-3 type piezoelectric composite have low dielectric constant, density and acoustic impedance. The distance between transducer and reflector was in good agreement with the distance calculated from the longitudinal velocity of the specimens and receiving time observed pulse-echo responses on the ultrasonic transducer analyzer.
박정규,오훈규,손무현,김현희,전언주,정의달 대한내분비학회 2012 Endocrinology and metabolism Vol.27 No.2
A pheochromocytoma is a neuroectodermal tumor that originates from the chromaffin cells of the sympathetic system. It has typical symptoms or signs, such as periodic attacks of paroxysmal hypertension, palpitation, headache, and sweating, related to an increased catecholamine secretion. Types of catecholamine secreted from tumors are usually norepinephrine and epinerphrine. There are a few reports of dopamine-secreting pheochromocytoma with absence of other catecholamines secretion. Here, we report the case of a 59-year-old man with dopamine-secreting pheochromocytoma, with no typical symptoms or signs