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      • 최근 임상에서 분리된 그람음성 막대균의 항균제 감수성 검사의 비교

        박창은 남서울대학교 2011 남서울대학교 논문집 Vol.17 No.2

        Recently, the emergence of antibiotic resistant bacteria due to abuse of antimicrobials, pathogenic bacteria from bacteria infections, and various antibiotic resistant bacteria tends to increase. In 2005 and 2008, clinical isolated bacteria were investigated at some hospitals situated in Gyeonggi-do. The most isolate bacteria, such as E. coli, K. pneumoniae, P. mirabilis, and S. marcescens) were investigated by year and their susceptibility and resistance to several antibiotics were studied. In 2008, the resistance E. coli to cephalothin and ticacillin increased by 62%. The resistance of K. pneumoniae to cefepim and ceftriaxone increased by 34%, 22% respectively. The resistance of P. mirabilis to aztreonam and cefazolin increased by 49%, 35% respectively. The resistance of S. marcescens to ceftazidim increased by 13%. In conclusion, this study showed the increased resistance of clinical isolated gram negative rods. Therefore, it is necessary to investigate the strain type, specimen type, and duration of antibiotic resistance by category. Key Words : antimicrobial resistance, K. pneumoniae, P. mirabilis, ESBL, Cephalothin

      • KCI등재

        D. H. 로렌스의 『무지개』 연구 : 상징의 서술형식

        박창도 한국현대영어영문학회 1994 현대영어영문학 Vol.36 No.1

        My argumentation is that The Rainbow which is hailed as the greatest novel of D.H.Lawrence by the major critics is not only an impressive fictional interpretation of a part of English social and cultural history over three generations, but also a symbolic version of the operation of the unknowable forces of life within the self and within society. This novel can be interpreted in terms of dualism. The motif of light and dark, death and rebirth, consciousness and unconsciousness are constantly used throughout the novel. The main difficulties in the language of The Rainbow lie not so much in the rural dialect words but in the somewhat exaggerated expression of the philosophic thought. To understand the events of the novel on a simple level is generally no problem, but to appreciate the full significance of these events and their influence upon the inner lives of the protagonists requires careful search of the meaning of symbols and ritual scenes originated from biblical and pagan myth. Lawrence's interest in relationships goes beyond what a mere chronicle would require. He is absorbed by the subtle interplay between the fact and imagination that draws people together or allows them to drift apart. For instance, the proposal of marriage to Lydia can hardly happen on the level of ordinary human contact. The scene of proposal is evocative. Anna is elated by the unknown quality within Will, and Ursula tries to live her own self-contained life. And all we need do is to decode symbols and the symbolic ritual scenes.

      • KCI등재

        Evaluation of Pregnancy and Thyroid Function

        박창은 대한임상검사과학회 2018 대한임상검사과학회지(KJCLS) Vol.50 No.1

        During early pregnancy, before the development of a functioning thyroid gland, thyroid stimulating hormone (TSH) is a very sensitive marker of thyroid dysfunction during pregnancy. Normal values have been modified during gestation with a downward shift. The fetus is influenced by the TSH supplied by the mother. TSH and free thyroxine (FT4) concentrations vary during pregnancy and conventional units can vary between laboratories. A downward shift of the TSH reference range occurs during pregnancy, with a decrease in both the lower and upper limits of maternal TSH, relative to the typical non-pregnant TSH reference range. Each laboratory produces its own reference TSH and FT4 concentrations because there are many different assays that yield different results in pregnancy. Therefore, automated immunoassays used for serum FT4 analysis are still used widely, but the important considerations discussed above must be noted. The use of population-based, trimester-specific reference ranges remains the best way to handle this issue The slight downward shift in the upper reference range of TSH occurring in the latter first trimester (7∼12 weeks) of pregnancy, typically not observed prior to 7 weeks. Their use indicates high or low levels in a quantitative manner independent of the reference ranges. These data highlight the importance of calculating population-based pregnancy-specific thyroid parameter reference intervals. A precision medicine initiative in this area will require the collection and analysis of a large number of genetic, biological, psychosocial, and environmental variables in large cohorts of individuals. Large prospective randomized controlled trials will be needed to resolve these controversies.

      • KCI등재

        경주지방의 무미 또는 단미 형태의 개(경주개 동경이)의 혈청 단백질의 분획에 대한 실태조사

        박창은 ( Chang Eun Park ), 이은우 ( Eun Woo Lee ), 성기창 ( Ki Chang Sung ), 최석규 ( Seog Gyu Choi ) 한국가축위생학회 2010 韓國家畜衛生學會誌 Vol.33 No.3

        Serum proteins of Korean native dogs (Gyeongju DongGyeong dogs) was analyzed by capillary electrophoresis system. Electrophoretic patterns showed six fractions. Total serum protein and ratio of albumin to globulin were 5.99±0.83 (g/dl) and 1.41±0.29 (g/dl) in DongGyeong dogs. Relative percentages of total serum albumin and α-1, α-2, β-1, β-2, γ-globulin fraction were 57.94±5.43, 3.15±2.30, 7.49±4.09, 9.43 ±3.50, 7.63±5.70, and 14.36±7.63, respectively. It was observed that β-globulin was higher than other fractions. The most striking alternation with age was founded in the γ-fractions. Also, it was observed that ratios of albumin to globulin in DongGyeong dogs were higher than on other dogs.

      • KCI등재

        요가와 명상 중심의 산림치유 프로그램이 성인의 기분상태와 스트레스 반응에 미치는 효과

        박창은,김동준,박광수,신창섭,김윤희 한국환경생태학회 2018 한국환경생태학회지 Vol.32 No.6

        The purpose of this study is to verify the effects of yoga and meditation-focused forest healing programs on profiles of mood states and stress reactions of adults. We tested 17 adults who agreed to participate in the experiments that were conducted for 2 nights and 3 days between September 8 to 10, 2017 in the healing forest located at Hongcheon-gun, Gangwon-do. The test used the simplified version of the inventory for the profile of mood states (K-POMS-B: Korean version of Profile of Mood States-Brief) and the stress response inventory as the measuring tools. For data analysis, we examined the differences in the profile of mood states and stress response of subjects before and after participation in the program through the paired T-tests with the SPSS 24.0 program. The analysis of the impact of the yoga and meditation-focused forest healing program on the profile of mood states of the test subjects showed the statistically significant reduction of the total score of the profile of mood states. Although the vigor among sub-level inventories increased, it was not statistically significant. But the tension, depression, anger, fatigue, and confusion showed a statistically significant reduction. The analysis of the impact of the yoga and meditation-focused forest healing program on the stress response of the test subjects showed a statistically significant reduction. Among sub-level inventories, the tension, somatization, anger, depression, fatigue, and frustration showed a statistically significant reduction, but the aggressiveness did not. It is expected that the results of this study can be utilized in the future as reference data for clarifying the effects of yoga and meditation-focused forest healing programs. 본 연구는 요가와 명상 중심의 산림치유 프로그램이 성인의 기분상태와 스트레스 반응에 미치는 효과에 대하여검증하고자 하였다. 실험에 동의한 성인 17명을 대상으로 강원도 홍천군 소재의 치유의 숲에서 2017년 9월 8일부터10일까지 2박 3일 동안 실시하였다. 측정도구는 단축형 기분상태 척도(K-POMS-B: Korean version of Profile of Mood States-Brief)와 스트레스 반응 척도(Stress Response Inventory)를 사용하였다. 자료분석은 SPSS 24.0 프로그램을 사용하여 대응표본 t-검정을 통해 프로그램 참가 전과 후의 기분상태와 스트레스반응 차이를 살펴보았다. 요가와 명상 중심의 산림치유 프로그램이 성인의 기분상태에 영향을 미치는가를 알아본결과, 기분상태 총점은 통계적으로 유의미하게 감소하였다. 하위척도 중 활기는 증가하였으나 통계적으로 유의미하지않았고 긴장, 우울, 분노, 피로, 혼돈은 통계적으로 유의하게 감소하였다. 요가와 명상 중심의 산림치유 프로그램에참여한 성인의 스트레스 반응에 영향을 미치는가를 알아본 결과, 스트레스 반응은 통계적으로 유의미하게 감소하였다. 하위척도 중 공격성을 제외한 긴장, 신체화, 분노, 우울, 피로, 좌절은 통계적으로 유의미하게 감소하였다. 본 연구결과가 향후 요가와 명상 중심의 산림치유 프로그램의 효과를 밝히는 기초자료로 활용될 수 있기를 기대한다

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