天皇巡幸의 展開와 民衆 : 천황순행의 전개와 민중

박진우 부산대학교 사학회 1999 釜大史學 Vol.23 No.-

주의력결핍과잉행동장애에서 Alpha-2A-Adrenergic 수용체 유전자와 Methylphenidate 반응과의 연관성에 대한 연구

박진우,김재원,조수철,김붕년,신민섭,홍순범,박은진,김효진,박민현,김붕년 대한신경정신의학회 2011 신경정신의학 Vol.50 No.5

Objectives The aim of this study was to examine the association of the ADRA2A MspI and DraI polymorphisms with methylphenidate (MPH) response in Korean children with ADHD. Methods The present study included 112 children and adolescents with ADHD (mean age= 9.1±2.1 years), consisting of 92 boys (82.1%) and 20 girls (17.9%). ADHD was diagnosed based on the DSM-IV criteria using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version (K-SADS-PL). For the clinical evaluation of the ADHD subjects, the ADHD Rating Scale-IV (ADHD-RS) and Clinical Global Impression (CGI) were administered at baseline and 8 weeks after MPH treatment. ADRA2A MspI and DraI polymorphisms were genotyped. The χ2 test was used to evaluate the relationship between the ADRA2A genotype and the response to MPH. The correlation between the genotype of ADRA2A and the change in the ADHD-RS scores after MPH treatment was assessed using the analysis of variance test and t-test. The significance level was set at p=0.01. Results No significant association was found between the genotypes of the ADRA2A MspI or DraI polymorphisms and MPH treatment response according to the CGI-improvement score (p>0.05). Comparing the changes in ARS scores after MPH treatment according to the genotypes of the MspI or DraI polymorphisms, we found no significant differences between subjects with different genotypes (p>0.05). Conclusion Our results do not support the significant association between the MspI genotype and MPH response in Korean ADHD subjects, which was previously reported. In addition, we document no evidence of association between the DraI polymorphism and MPH treatment response in the Korean ADHD population.

Covid 19 시대, 교회 공동체 구성원을 위한 정신건강사회복지 실천의 방향성 : 대면모임 재개에 따른 교회 공동체 경험을 중심으로

박진우 한국실천신학회 2022 신학과 실천 Vol.- No.82

본 연구는 정부의 교회 대면 모임 재개 이후의 교회 공동체 구성원의 심리사회적 경험을 탐색했다. 2022년 6월부터 10월까지 8인의 기독교인의 대상으로 면담 및 분석 이 진행 되었다. 본고의 연구방법은 본 연구의 목적에 적합한 질적 사례 연구로 진행 되었다. 면담 결과 확인된 6개의 주제 모임은 다음과 같다. 공동체 구성원은 ‘교회공동체 에 애착을 가짐’, ‘교회공동체에서 부정적인 경험을 함’, ‘대면모임 재개로 공동체 모임 을 시작함’, ‘코로나로 인한 교회공동체의 어려움 보게 됨’,‘대면 모임에 참여하면서 심 리사회적 어려움을 경험함’, ‘주체성을 갖고 현 상황을 바라봄’으로 나타났다. 더불어 연구결과를 토대로 공동체 구성원의 정신건강을 위한 정신건강사회복지 실 천의 방향성을 제시하면 다음과 같다. 첫째 공동체의 높은 응집력은 교회 구성원의 정신건강에 긍정적인 영향을 미치는 것이 확인 되었다. 따라서 교회 공동체 응집력을 높이기 위한 노력이 필요하다. 둘째 대면모임 재개에 따른 교회공동체 구성원의 심리사회적 문제를 해소하기 위한 노력의 일환으로 상담 및 자조모임의 활성화가 필요하다. 셋째 교회의 코로나상황에 대한 합리적 판단 및 대처에 구성원의 주체성이 도움이 되는 것이 확인 되었다. 따라서 공동체 구성원의 주체성을 높이기 위한 노력이 필요 해 보인다. 이와 같은 연구 결과를 토대로 공동체 구성원의 대면모임 재개에 따른 심리사회적 혼란감이 해소되기를 바란다. This study explored the psychosocial experiences of church community members after the government resumed face-to-face church meetings. Interviews and analysis were conducted with eight Christians from June to October 2022. The research method of this paper was conducted as a qualitative case study suitable for the purpose of this study. The seven thematic groups identified as a result of the interview are as follows. Community members ‘have attachment to the church community’, ‘have negative experiences in the church community’, ‘Community meeting begins with the resumption of face-to-face meetings’, ‘I see the difficulties of the church community due to Corona’, ‘Experiencing psychosocial difficulties while participating in face-to-face meetings’, ‘Looking at the current situation with subjectivity’ appeared as In addition, based on the research results, the direction of mental health social welfare practice for the mental health of community members is suggested as follows. First, it was confirmed that the high cohesion of the community had a positive effect on the mental health of church members. Therefore, efforts are needed to increase the cohesion of the church community. Second, it is necessary to activate counseling and self-help groups as part of an effort to solve the psychosocial problems of church community members following the resumption of face-to-face meetings. Third, it was confirmed that the subjectivity of the members is helpful in rational judgment and response to the corona situation of the church. Therefore, it seems necessary to make efforts to increase the subjectivity of community members. Based on the results of this study, it is hoped that the psychosocial confusion caused by the resumption of face-to-face meetings of community members will be resolved.

새로운 출발을 위하여

박진우 샘터사 2003 월간 샘터 Vol.34 No.4

Properties of solution processed ITO film by using nanoparticle ink in various annealing atmospheres

박진우,이미정,홍성제 한국공업화학회 2014 한국공업화학회 연구논문 초록집 Vol.2014 No.0

Fentanyl 을 사용한 마취유도

박진우 대한마취과학회 1989 Korean Journal of Anesthesiology Vol.22 No.6

We evaluated the efficacy as an anesthetic induction agent and cardiovascular effects of fentanyl in sixty patients with myocardial ischemia on electrocardiogram, who were scheduled for elective operations of more than two-hour duration. In addition, the effects of pretreatment with pancuronium and/or lorazepam prior to anesthetic induction were evaluated on the induction speed, the incidence and severity of skeletal muscle rigity, heart rate, and systolic blood pressure. All the patients were given 30μg/kg of fentanyl and divided into four equal groups of fifteen patients according to pretreatment drugs administered before fentanyl. The results were as follows: 1) Eighty-seven percent of the patients in control group (pretreated with saline)were rendered unconscious during or one minute after infusion of 30μg/kg of fentanyl. 2) Pretreatment with lorazepam before fentanyl significant#ly increased the induction speed (p$lt;0.025), but was not significantly correlated with the incidence and severity of skeletaluscle rigidity. Pancuronium pretreatment significantly decreased the incidence and severity of skeletal muscle rigidity (p$lt;0.01) but was not significantly correlated with the induction speed, Pretreatment with lorazepam plus pancuronium significantly increased the induction speed (p$lt;0.025) and significantly decreased the incidence and severity of skeletal muscle rigidity (p$lt;0.01). 3) Saline pretreatment and pancuronium pretreatment did not significantly change heart rate or systolic blood pressure, but both lorazepam poretreatment and lorazepam-pancuronium pretreatment decreased heart rate or systolic blood pressure (p$lt;0.05), which were within thirty percent of preanesthetic values. 4) All the patients did not exhibit significant changes in heart rate or systolic blood pressure immediately after, in comparison to, immediately before tracheal intubation or skin incision (p$gt; 0.05). From the above results, it is concluded that anesthetic induction with 30 μg/kg of fentanyl produces profound analgesia and amnesi, stable cardiovascular dynamics, and a minimum of problems, and pretreatment with small doses of lorazepam and pancuronium before fentanyl facilitates not only a rapid loss of consciousness but also a reduction in the incidence and severity of fentanyl-induced rigidity.

확률화 회답모형의 정도(精度)에 관한 연구

박진우 수원대학교 기초과학연구소 1993 基礎科學論文集 Vol.2 No.-

The performances of Randomized Response Models are investigated. RRM provides a method to get more reliable informations about highly personal matters. However, when the proportion of a sensitive attribute is very small, the precision of estimators from RRM may be poor. In that case use of RRM is restricted. In this paper, the performances of RRM are investigated when population proportion of the sensitive attribute changes.

정상 인체 멜라닌세포에서 endothelin-1 receptor antagonist가 melanin생성에 미치는 영향에 관한 연구

박진우,이종석,황규왕,김정하 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

In the normal skin, melanocytes maintain their constant population and their melanogenic activity in steady state, but respond to several stimulus such as UV radiation and chemical irritation, to accentuate proliferation and differentiation, leading to hyperpigmentation of the skin. Human Keratinocytes produce and secrete endothelin-1, which can be strong mitogens for human melanocytes. The paracrine linkage of endothelin-1 between keratinocytes and melanocytes suggested that endothelin-1 is intrinsic mediators for human melanocytes in UVB-induced pigmentation. The purpose of this study is to investigate the new whitening agent, which improve the hyperpigmentation by inhibiting the ET-1. So, we add ET-1 and five kinds of ETRA into the cultured normal human melanocyte and then three days later, each ETRA on ET-1 was measured melanocyte number and inhibitory effect of melanin synthesis, respectively. In this study, ETRA has a inhibitory effect on ET-1 induced melanocyte proliferation and melanogenesis. ETRA I has a strong inhibitory effect on melanocyte proliferation and ETRA Ⅱ has a strong inhibitory effect melanogenesis. western blotting results shows negative. It may be due to the processing error of protein denaturing or low antigen -antibody affinity. But, we also confirm that ETRA Ⅱ has a inhibitory effect of tyrosinae synthesis by RT-PCR

韓國人頭蓋骨의 X線學的 測定値

朴鎭雨,金斗祚 慶北大學校 1964 論文集 Vol.8 No.-

1. Statistical measurements are done on normal Korean adult skull, male 100 persons, female 40 persons, total 150 persons, for the length, breadth, cephalic index, heihgt, A-P diameter and depth of the sella turcica, basal angle, facial angle and calcification of teh pineal gland. 2. Most of the Korean skulls (85%) are brachycephalic skull. 3. Calcification of the pineal gland is seen in 18%.

탈회된 상아질면에 혈소판유래성장인자-BB적용시간이 치은섬유아세포의 증식에 미치는 영향

박진우 慶北大學校 齒科大學 1996 慶北齒大論文集 Vol.13 No.-

섬유아세포의 이주와 증식에 중요한 역할을 하는 것으로 알려진 PDGF-BB를 이용하여 테트라사이클린으로 탈회시킨 치근면에 PDGF-BB의 다양한 적용시간에 따른 증식세포수를 측정해 봄으로써, PDGF적용시간이 섬유아세포의 증식에 미치는 효과를 알아보기 위하여 본 실험을 실시하였다. 교정치료를 목적으로 내원한 환자의 발거한 소구치를 이용하여 상아질절편을 제작하여 시편으로 사용하였다. 100mg/ml 농도의 테트라사이클린으로 5분간 탈회시킨 시편을 50ng/ml 농도의 PDGF-BB로 30초, 1분, 2분, 4분, 8분 동안 처리하고 성장인자를 적용하지 않은 시편을 대조군으로 하여 각 시편을 24well 조직 배양접시에 넣고 1 × 10 exp (5)개의 치은섬유아세포를 가진 배양액 1ml 씩을 넣어 6시간 배양한 후 새로운 배양접시로 옮기고 24, 48, 72시간동안 배양하여 각 시간대별로 0.05% trypsin/0.02% EDTA로 처리하고 세포를 분리하여 광학위상차현미경하에서 세포수를 측정하고 시편의 단위면적당 세포수를 계산하여 다음과 같은 결과를 얻었다. 세포증식률의 측정실험에서 24, 48, 72시간 공히 대조군과 비교시 PDGF-BB 적용시간의 증가에 따라 증식세포수가 증가하였으며 4분 및 8분 적용군에서 세포증식률의 현저한 증가양상을 보였다. PDGF-BB적용군과 테트라사이클린만 처리한 대조군과 비교시 24, 48시간에서는 PDGF-BB 1분 적용군부터 세포수가 증가를 관찰할 수 있었으나 적용시간 2분까지는 그 정도가 미약하였으며 4,8분 적용군에서 24,48,72시간 모두에서 대조군과 비교시 세포수 증가가 현저한 것을 관찰할 수 있었다. PDGF-BB 적용군사이에서는 4분 적용군이 세포증식률이 가장 높은 것으로 나타났고, 8분 적용군에서는 4분 적용군에 비해 24, 48, 72시간 모두에서 세포증식률이 감소하는 경향을 보였다. 이상의 연구를 미루어 볼 때 치은섬유아세포의 증식률에서 PDGF-BB 4분 적용군이 24, 48, 72시간 모두에서 타군과 비교시 현저한 증가를 보였으므로 탈회된 상아질을 PDGF-BB의 주적용부로 하였을때 50ng/ml농도의 PDGF-BB사용시 4분정도의 적용시간이 섬유아세포의 증식을 이루는데 있어서 가장 적절한 시간이 될 것으로 사료된다. Platelet-derived growth factor(PDGF) is one of the polypeptide growth fators. PDGF has been reported as a biological mediator which requlates activities of wound healing process including the cell proliferation, migration and metabolism. Recent studies indicated that demineralized root surface as the primary site for growth factor application has advantages over other application method, especially due to binding capacity of growth factor for exposed matrix component of demineralized dentin surface. The purpose of this study is to evaluate optimal application time of PDGF-BB on proliferation of human gingival fibroblasts using demineralized dentin surface as primary application site. Human gingival fibroblasts and dentin slabs were prepared from the first premolar tooth extracted for the orthodontic treatment, cells were cultured in DMEM/10% FBS at the 37℃, 5% CO_2 incubator. All of the dentin slabs were preconditioned with Tetracycline HCl(100mg/ml) solution and rinsed in PBS. In the cell proliferation experiment, experimental group was immersed in DMEM containing 10% FBS, 50ng/ml PDGF-BB during different time(30sec, 1, 2, 4, 8 minutes) and dried. Cells at concentration of 1 × 10 exp (5) cells/ml were seeded in each culture well which contained dentin slabs and incubated for 6 hours. Then, all of the dentin slabs were moved into new 24 well culture dish and incubated for 24, 48, 72 hours. The cell counting was done by hemocytometer with inverted phase contrast microscope after trypsinization. The results were as follows: The application of PDGF-BB for 1, 2 min slightyly increased the number of gingival fibroblasts, and the application of PDGF-BB for 4, 8 min prominetly increased the number of gingival fibroblasts. The application of PDGF-BB for 4 min showed maximum proliferation rate of gingval fibroblasts at 24, 48, 72 hours, and the application of PDGF-BB for 8 min showed less proliferation rate of gingival fibroblasts compared to the application of PDGF-BB for 4 min at 24, 48, 72 hours. In conclusion, the application of PDGF-BB for 4 min appeared to be optimal to obtain maximum proliferation of gingival fibroblasts using demineralized dentin surface as primary applicaton site of PDGF-BB.