가방 하중의 크기와 방식에 따른 척추 정적 자세의 변화

박용현,김영관,김윤혁,Park, Yong-Hyun,Kim, Young-Kwan,Kim, Yoon-Hyuk 대한의용생체공학회 2011 의공학회지 Vol.32 No.3

The aim of this study was to investigate the alteration of lumbar spine and trunk postures on different load-carrying types and amounts under static loading. Two load-carrying types(unilateral carrying: UC vs. bilateral carrying: BC) and four different loads(0, 5, 10, and 15 kg) were randomly tested in this study. Carrying a heavy bag would affect human body posture, specifically lumbar spine curvature, which is considered as one of sources of back problems. Previous studies have not paid attention to the approach of the multisegment model of the lumbar spine and trunk. This study separated two compartments of trunk segment(the lumbar and thorax) in the analysis. The multisegment model of the lumbar spine in addition to Helen-Hayes marker set was used. Eight motion analysis cameras and a force plate were utilized. Ten male subjects(mean mass, $70.6{\pm}3.97$ kg; mean height, $178{\pm}4.18$ m) having no musculoskeletal disease participated in this study. We analyzed trunk angles in three anatomical planes and the spinal curvature in sagittal and frontal planes. Increased loading in both UC and BC significantly resulted in increases in trunk forward lean but only UC induced increases in trunk lateral lean. In addition, increased loading in BC produced flatten lumbar curvature in sagittal plane. As far as coupling motion, subjects tended to use axial rotation of the lumbar spine in transverse plane in response to increased UC loading. Finally, it is concluded that the increased static loading in UC rather than in BC tends to causes combined alterations of the spinal postures(sagittal and transverse planes together), which would be vulnerable to improper mechanical stresses on the spine.

워커(walker)사용 유무가 정상 노인의 보행 동작과 일어서기 동작의 운동학적 변인과 근활성도에 미치는 영향

박용현(Yong-Hyun Park),김영관(Young-Kwan Kim),송원경(Won-Kyung Song),박대성(Dae-Sung Park),김윤혁(Yoon Hyuk Kim) 한국HCI학회 2011 한국HCI학회 학술대회 Vol.2011 No.1

실직으로 인한 임금 손실과 지속 원인에 대한 연구

박용현 ( Young Hyun Park ) 한국노동경제학회 2010 勞動經濟論集 Vol.33 No.1

이 논문은 한국노동패널 조사 자료를 이용하여 실직자들이 겪는 임금 손실의 정도를 실직 발생 직후에서 부터 4년 후까지 분석하였다. 종전에 국내에서 이루어진 연구들에서는 주로 실직 직후에 발생하는 손실에 초점이 맞춰졌는데, 실직으로 인한 손실이 지속될 경우 이는 손실을 과소 추정하는 것이 된다. 논문의 분석 결과에 의하면 실직 발생 4년 후에도 실직으로 인한 임금 손실이 유의미하게 지속되는 것으로 나타났으며, 이는 실직으로 인해 발생하는 일자리 경험의 손실과 반복 실직의 발생에 크게 영향 받은 결과인 것으로 나타났다. This paper investigates the wage losses of displaced workers, using data from the Korean Labor & Income Panel Study. Previous Korean studies were only to estimate the wage losses shortly after job displacement. However, if the wage losses persist, those results seem to under-estimate the effects of displacement. Our findings show that the wage reductions are quite persistent 4 years after displacement. And much of this persistence can be explained by the lost labor market experience (lost opportunities to accumulate generalized skills) and additional job losses in the years following an initial displacement.

연속된 100명의 담석증 환자의 담석 분석

박용현(Yong-Hyun Park),이건영(Koen-Young Lee),김선회(Sun-Whe Kim),유환영(Hwan-Young Yoo) 대한외과학회 1998 Annals of Surgical Treatment and Research Vol.55 No.2

혈소판 및 Na+, K+-ATPase, cyclicAMP 포스포디에스테라제에 대한 해양천연물질의 작용

박용현(Young Hyun Park),장성근(Sung Keun Chang),김인규(In Kyu Kim),서영완(Young Wan Seo),신종헌(Jong Heon Shin) 대한약학회 1997 약학회지 Vol.41 No.3

The purpose of this investigation was to determine the inhibition of Na+,K+-ATPase, cyclicAMP phophodiesterase and platelet activation by secondary metabolites isolated from marine organisms. The secondary metabolites were isolated and identified as six diterpenoids(1 : astrogorgin, 2 : ophirin, 3 : calicophirin B, 4, 5 and 6 : cladiellin) from the dichloromethane extract of Muricellajsp., four ceramides(1,2,3, and 4) from Acabaria undulata and three antharaquinones(1,2 : crysophanol, and 3 : physcion) from Urechis unicintus. The results demonstrated that diterpenoids(2,3, and 4) showed the inhibition of cyclicAMP phosphodiesterase, and ceramides(1,3, and 4) showed the inhibition of cyclicAMP phosphodiesterase and thrombin(0.1 units/ml)-induced aggregation of washed rabbit platelet, and anthrapuinones((1,2, and 3) showed the inhibition of Na+,K+-ATPase. Among the anthraquionones, 1,2-dimethoxy-3-methyl-8-hydroxy-anthraquinone(1) showed the inhibition of collagen(1.0 mcg/ml)-induced aggregation in a concenration-dependent manner with IC50 value of 42.8 mcM.

원발성 담낭암 65예에 대한 임상적 고찰

박용현(Yong Hyun Park),김선회(Sun Whe Kim),박영근(Young Keun Park) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1

N/A A clinical review of 65 cases with primary carcinoma of the gallbladder who underwent exploratory laparotomy at the Department of Surgery, Seoul National University Hospital, during the period from Jan. 1977 to Dec. 1986 was carried out. The following results were obtained: 1) There were 25 males and 40 females with a sex ratio of 1 to 1.6, and the highest incidence appeared in sixth decade (40%). 2) The most prevalent duration of symptoms was from 1 month to 6 months (56.9%). 3) The clinical manifestations were right upper quadrant abdominal pain (78.5%), fever (29.2%), jaundice (24.6%), and indigestion (20%) etc. 4) The proportion of the patients who had gallstones (gallbladder) was 29.2%. 5) The liver function test was abnormal in 41.5%. Total bilirubin was increased in 29.2%, serum alkaline phosphatase was increased in 49.2%, SGOT/SGPT was increased in 40%, and leukocytosis was present in 38.5%. 6) The accurate preoperative diagnosis of gallbladder carcinoma was made in 30.8%. 7) The histopathologic types of the tumor revealed adenocarcinoma in 58 cases, squamous cell carcinoma in 4 cases, adenosquamous carcinoma in 2 cases, and anaplastic carcnoma in 1 cases. 8) According to Nevins classification, there were 1 stage I cases, 4 stage II cases, 8 stage III cases, 4 stage IV cases, and 48 stage V cases (73.8%). 9) The operative procedures performed were cholecystectomy alone (10), cholecystectomy and T-tube insertion (9), cholecystectomy, lymphadnectomy and hepatic wedge resection (13), internal drainage (3), and external drainage (11). Nineteen patients (29.2%) had undergone exploration and biopsy only. 10) The metastatic sites were liver (45), pericholedochal lymph nodes (34), omentum and peritoneum (19), and common bile duct (12) etc. 11) The operative mortality was 7.7%. 12) One year and five year survival rate were 36.7% and 26.1% respectively. We can conclude that aggressive surgical approaches including cholecystectomy, lymphadenectomy, and hepatic wedge resection are indicated in patients with tumors limited to the gallbladder wall. Patients with tumor extended to the cystic node or beyond are candidates for palliative surgery only.

남북통일에 따른 국가승계 문제

박용현 ( Young Hyun Park ) 조선대학교 동북아연구소 2002 동북아연구 Vol.15 No.-

혈액투석중인 만성 신부전 환자에서 혈청 Neopterin 농도에 관한 연구

박용현(Yong Hyun Park),문경협(Kyung Hyub Hyub),박광기(Kwang Ki Park),조규웅(Kyu Woong Cho),음선홍(Sun Hong Eum),김광선(Kwang Sun Kim),최기철(Ki Chul Choi),강영준(Young Joon Kang) 대한내과학회 1990 대한내과학회지 Vol.39 No.2

N/A Neopterin is a low-molecular-weight product released by human macrophages upon stimulation with interferon gamma. It permits the quantification of the level of cellulalr immune activation in vivo. We measured the level of serum neopterin and creatinine concentrations in 20 patients before and after hemodialysis in order to test whether hemodialysis induces specific activation of the T-lymphocyte macrophage axis. The results were as follows: 1) In normal adults, the serum neopterin level was 6.7±1.3 nmol/L with no sex difference. 2) In 20 hemodialysis patients, the serum neopterin level before hemodialysis was 246.2±97.6 nmol/L and increased significantly compared to normal adults (p<0.001). 3) In 20 hemodialysis patients, the serum neopterin level was 163.0±76.7 nmol/L after hemodialysis and decreased significantly (p<0.001), the neopterin/creatinine ratio was 25.4±14.7, 32.8±23.7 before and after hemodialysis, respectively, and there was no significant difference between both groups. 4) In groups of short-term hemodialysis (less than three months), the serum neopterin level was 248.4±100.6, 181.7±91.2nmol/L before and after hemodialysis, respectively. In groups of long-term hemodialysis (more than one year), the neopterin level was 244.0±99.9, 144.2±57.6 nmol/L before and after hemodialysis, respectively, and decreased significantly after hemodialysis in both groups (p<0.001), and there was no significant difference between both groups. 5) In 12 male hemodialysis patients, the serum neopterin level was 226.4±97.6, 145.5±60.5nmol/L before and in after hemodialysis, respectively, and in eight female hemodialysis patients, the serum neopterin level was 275.9±96.0, 189.1±94.4 nmol/L before and after hemodialysis, respectively, and decreased significantly in both groups (p<0,05, respectively). There was no significant difference between both groups.Neopterin is a low-molecular-weight product released by human macrophages upon stimulation with interferon gamma. It permits the quantification of the level of cellulalr immune activation in vivo. We measured the level of serum neopterin and creatinine concentrations in 20 patients before and after hemodialysis in order to test whether hemodialysis induces specific activation of the T-lymphocyte macrophage axis. The results were as follows: 1) In normal adults, the serum neopterin level was 6.7±1.3 nmol/L with no sex difference. 2) In 20 hemodialysis patients, the serum neopterin level before hemodialysis was 246.2±97.6 nmol/L and increased significantly compared to normal adults (p<0.001). 3) In 20 hemodialysis patients, the serum neopterin level was 163.0±76.7 nmol/L after hemodialysis and decreased significantly (p<0.001), the neopterin/creatinine ratio was 25.4±14.7, 32.8±23.7 before and after hemodialysis, respectively, and there was no significant difference between both groups. 4) In groups of short-term hemodialysis (less than three months), the serum neopterin level was 248.4±100.6, 181.7±91.2nmol/L before and after hemodialysis, respectively. In groups of long-term hemodialysis (more than one year), the neopterin level was 244.0±99.9, 144.2±57.6 nmol/L before and after hemodialysis, respectively, and decreased significantly after hemodialysis in both groups (p<0.001), and there was no significant difference between both groups. 5) In 12 male hemodialysis patients, the serum neopterin level was 226.4±97.6, 145.5±60.5nmol/L before and in after hemodialysis, respectively, and in eight female hemodialysis patients, the serum neopterin level was 275.9±96.0, 189.1±94.4 nmol/L before and after hemodialysis, respectively, and decreased significantly in both groups (p<0,05, respectively). There was no significant difference between both groups.

담낭암에서 DPC4/Smad4 유전자 변이에 관한 연구

이건영(Keon-Young Lee),김선회(Sun-Whe Kim),박상재(Sangje Park),박윤찬(Yoon-Chan Park),장진영(Jin-Young Jang),박용현(Young-Hyun Park) 대한외과학회 2002 Annals of Surgical Treatment and Research(ASRT) Vol.62 No.3

침생검으로 진단된 후신성 선종 1 예

박원석(Won Seok Park),황성하(Sung Ha Hwang),박용현(Yong Hyun Park),박주현(Joo Hyun Park),진동찬(Dong Chan Jin),김혜수(Hye Soo Kim),이종민(Jong Min Lee),이은희(Eun Hee Lee),김석영(Suk Young Kim),방병기(Byung Kee Bang) 대한신장학회 2001 Kidney Research and Clinical Practice Vol.20 No.5

Metanephric adenoma is a very rare benign renal tumor; only 100 well-documented cases have been reported to date. Metanephric adenoma occurs at all ages, most commonly in the fifth and sixth decades. There is a 2 : 1 female preponderance. They appear to be benign tumors with no malignant potential, and their chief importance is related to the fact that they are most often misinterpreted as renal cell carcinoma or Wilms' tumor. Its light microscopic features are very characteristic, and imunohistochemical and electron microscopic studies are not critical to the diagnosis. We have experienced a case of renal tumor in a 44-year-old female patient diagnosed by ultrasonography-guided needle biopsy which showed small, tightly packed acini or tubular and papillary structures. The patient underwent right nephrectomy. We report metanephric adenoma diagnosed by ultrasonography-guided needle biopsy, which is a very rare and unique case.