A Fluorescent Optode Membrane for pH Sensing under Extremely Acidic Condition

민재영,김형진 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0

We synthesized a donor-acceptor conjugated dye (6) possessing an acryloyl group and prepared a pH-sensitive optode membrane via the photo-copolymerization of 6 with a mixture of HEMA and triethylene glycol dimethacrylate on a silanized glass surface. The optode membrane exhibited two absorption bands at approximately 370 and 450 nm, and a strong fluorescence at approximately 630 nm after excitation at 450 nm. The optode membrane displayed a ratiometric absorption response to pH changes. As the pH increased from 0.0 to 2.0, the absorbance ratio of the membrane increased. The fluorescence of the membrane increased with increasing pH from 0.0 to 2.0 and showed a good linear response to pH changes in this range. The membrane operation was reversible, reproducible, and stable for repeated measurements under acidic conditions. The membrane showed an operable response time and good tolerance for high salt concentrations.

A Fluorescent Sensor Film for Detecting pH of Acidic Solutions

민재영,김형진 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-

A push-pull conjugated dye (DCMP) was covalently immobilized on a silanized glass surface to produce a high sensitivity pH sensor film for operating in the acidic region. A pH-sensitive sensor film was prepared by photo-initiating copolymerization of a modified DCMP (DCMA), 2-hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate on the silanized glass surface. The absorbance of the sensor film increased with increasing pH between pH 2.0 and 5.0, and the fluorescence intensity of the film also increased about 50 times with increasing pH in the same pH range. The sensor film was reversible and reproducible under acidic conditions. The sensor film showed a relatively short response time between 20-50 seconds and high selectivity for proton in the presence of various metal ions.

산성 용액의 pH를 감지할 수 있는 형광 센서막

민재영,김형진 대한화학회 2020 대한화학회지 Vol.64 No.2

A push-pull conjugated dye (DCMP) was covalently immobilized on a silanized glass surface to produce a high sensitivity pH sensor film for operating in the acidic region. A pH-sensitive sensor film was prepared by photo-initiating copolymerization of a modified DCMP (DCMA), 2-hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate on the silanized glass surface. The absorbance of the sensor film increased with increasing pH between pH 2.0 and 5.0, and the fluorescence intensity of the film also increased about 50 times with increasing pH in the same pH range. The sensor film was reversible and reproducible under acidic conditions. The sensor film showed a relatively short response time between 20−50 seconds and high selectivity for proton in the presence of various metal ions. 산성 영역에서 작동하는 고감도 형광 pH 센서막을 제조하기 위하여 실란화된 유리 표면 상에 push-pull 공액 염료 (DCMP)를 공유결합에 의해 고정화하였다. DCMP 유도체(DCMA), 2-hydroxyethyl methacrylate (HEMA)및 triethylene glycol dimethacrylate의 혼합물을 광개시 공중합하여 pH 감응성 형광센서막을 제조하였다. 분광학적 측정 결과, pH 2.0−5.0 사이에서 pH 가 증가함에 따라 센서막의 흡광도가 증가하였으며, 같은 pH 범위에서 pH 증가에 따라 센서막의 형광 세기도 약 50배 정도 증 가하였다. 산성 조건에서 pH 변화에 대한 센서막의 감응은 가역적이고 재현성이 우수하였다. 또한 센서막은 20−50초 사이의 비 교적 짧은 감응 시간과 여러 금속이온 존재에서 수소 이온에 대해 높은 선택성을 나타내었다.

A Fluorescent Sol-Gel Film for Measuring pH Values in Acidic Environments

민재영,김형진 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-

This article describes the fabrication and pH sensing characteristics of a sol-gel-derived fluorescent sensor film. A fluorescent pH sensor film operating in an acidic solution was prepared by synthesizing a fluorescent dye having triethoxysilyl pendant group (DPMS) and covalently immobilizing DPMS on a sol-gel porous film. The sensor film shows maximum absorption near 374 nm and a maximum emission near 564 nm when irradiated with ultraviolet light at 374 nm. Both the fluorescence intensity and the absorbance of the sensor film increased with increasing pH. In particular, the fluorescence intensity of the sensor film increased 2.1 times in the pH range of 0.3-6.5. The sensor film is reproducible, reversible, and stable even after repeated measurements in acidic solution, and it has a long life of more than 1 month without dye leaching.

청소년에서 비정상 자궁출혈에 대한 관찰

민재영,이민경,변승원,김진휘,김연희 ( Yeon-Hee Kim ),이희중,박태철,송재연 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: 자궁출혈을 보이는 여성에서 자궁내막 조직검사는 매우 유용하며 치료의 방향을 결정하는데 매우 중요한 자료가 된다. 하지만 20세 이하 청소년에서는 자궁내막조직검사를 하기 어려운 것이 현실이다. 이에 5년간 조직검사를 시행한 결과를 토대로 의심되는 질환군에 대한정립이 하고자 한다. 방법: 2010~2014년 5년간 시행한 20세 이하 여성 (11~20세)에서 자궁내막조직검사를 58명을 대상으로 후향적 chart review를 통한 문진, 혈액검사, 호르몬, 초음파 검사와 자궁내막조직검사 결과를 확인하였다. 결과: 58명 중 2명이 임신력이 있었으며, 생리주기가 불규칙적인 여성은 35명, 규칙적인 여성은 23명이였다. 10이상의 생리기간을 보이는 경우는 30명 (52%)였으며 생리양이 과도하게 많은 경우는 41%, 중등도 이상은 40%로 대부분에서 생리양의 과다를 보였다. 빈혈이 12g/dL이하인 경우는 23명 (40%)였으며 그 중 4명은 Hb 8g/dL를 보였고, ferritin 감소를 보이는 경우는 14명(24%)였다. FSH/E2는 대부분 정상 가임기 여성의 수치를 보였으며, 간수치와 혈액응고 수치의 이상을 보이는 여성은 없었다. 대부분 특별한 호르몬 이상은 보이지 않았다. 갑작스런 체중변화를 보였던 환자는 6명 (10%)였으며, 초음파 상 자궁근종 등의 자궁병변은 보이지 않았으며, 난소에서 다낭성 변화를 보인 경우는 25명(43%), 난포를 보이는 경우는 11명 (19%), 난소낭종 2명, 나팔관낭종을 보이는 1명이 있었다. 조직검사 결과 proliferative phase 31명(53%), secretory phase 5명(9%), menstrual phase 2명 (3%), basal endometrium 1명(2%), endometrial hyperplasia 12명(21%), endometritis 4명(7%), endometrial polyp 1명(2%), conception 2명(3%)의 결과를 보였다. 결론: 청소년기에 나타나는 비정상자궁출혈 환자는 원인은 대부분 무배란과 관련되어 나타난다. 절반 이상의 환자에서 자궁내막조직검사에서 증식기 소견을 보이는 결과와도 상통된다. 하지만 자궁내막증식증, 자궁내막염, 용종 등 자궁내막병변이 원인인 경우도 30%로 나타나 상당한 비중을 차지한다. 비록 성경험이 없는 청소년 여성인 경우에도 의심될 경우 적극적인 자궁내막조직검사가 필요한 이유가 되겠다.

8체질(體質) 설문지(說問紙)의 타당도(妥當度), 신뢰도(信賴度)에 관한 연구(硏究)

민재영 ( Jae-young Min ),김민용 ( Min-yong Kim ),박영재 ( Young-jae Park ),박영배 ( Young-bae Park ) 대한한의진단학회 2007 大韓韓醫診斷學會誌 Vol.11 No.2

Background: Eight-Constitution Medicine (ECM) classifies the human body into eight constitutions. Diagnosis of discrimination of the eight constitutions depends on a unique pulse diagnosis. However, pulse diagnosis is subjective and requires vigorous training. Objectives: This study aims to analyze the validity and reliability of the Eight-Constitution Questionnaire as a diagnostic method. Methods: Participants of this study were outpatients in six ECM clinics located in Seoul. The resources were collected from 409 patients who were classified into one of the eightconstitutions according to their pulse types and their responses to constitution-acupuncture therapy. SPSS 13.0 for Windows was used for statistical analysis: factor analysis, reliability analysis, independent sample t-test, and multinomial logistic regression were used to verify the results. Results and Conclusions: 1. The proportion of participants` constitutions is in the order of Pancreotonia (23.7%), Colonotonia (19.8%), Pulmotonia (18.1%), Hepatonia (16.9%), Vesicotonia (8.1%), Cholecystotonia (7.3%), Renotonia (5.3%) and Gastrotonia (0.7%). 2. Sevencomponents and 74 items were selected through factor factor and relaibility analysis performed on about 251 items. 3. The firstcomponent`s mean is significantly higher in Pancreotonia than that in other constitutions (p<0.05). The second is in Pulmotonia and Colonotonia, whereas the third is in Hepatonia and Cholecystotonia. Fifth is in Vesicotonia, the sixth is in Colonotonia, and the fourth and seventh are not significant in specific constitutions. 4. The percentage that Pancreotonia is correctly predicted is 96.9%, Pulmotonia is 91.9%, Colonotonia is 91.4%, Hepatonia is 88.4%, Vesicotonia is 81.8%, Gastrotonia is 66.7%, Renotonia is 66.7%, Cholecystotonia is 30.0%, and the total percentage is 85.3%.

팔체질침 전문 한의사의 체질침 효과에 대한 인식조사

민재영 ( Jae-young Min ),박영재 ( Young-jae Park ),박재성 ( Jae-sung Park ),신용섭 ( Yong-sup Shin ),박영배 ( Young-bae Park ),이상철 ( Sang-chul Lee ),김민용 ( Min-yong Kim ) 대한한의진단학회 2007 大韓韓醫診斷學會誌 Vol.11 No.1

Objectives: The purpose of this research is to obtain basic data about the effects of Constitution-Acupuncture (CA) based on Eight-Constitution Medicine (ECM) by the expert CA Oriental Medical Doctors. Methods: The resources were collected from the internet survey method. 35 samples were collected. The SPSS 13.0 for windows and Answer Tree 3.0 was used for statistical analysis. Results: The results from this research are as follow. 1. The motivation that apply ECM to clinic are `Because ECM is effective for diagnosis, treatment and prevention against disease` 48.6% and `Because CA therapy is effective` 25.7%. 2. The advantage that CA therapy compare to the other acupuncture therapy are `Management and prevention against disease are available by ECM theory to a person who exact constitution is confirmed` 82.9%, `CA therapy is superior in treatment of hard symptoms to treat by the other acupuncture therapy` 80%, `Treatment effect is good` 77.1%, `Needle manipulation of CA is simple comparatively` 57.1%, `It is definite whether treatment effect is good or not` 54.3% and CA therapy is superior all in diseases of twelve category. 3. When the effects of CA is good, patients expressed much `Eyesight lightened`, `Took deep sleep at night`, `Fatigue decreased`, `Body is light`, `Feelings became refreshing` as well as `Symptoms were improved` and also physicians confirmed as those reactions whether treatment is effective. Conclusions: The research suggest that CA is effective therapy in clinic, and so further study is needed for CA therapy.

프로 스포츠 및 일반제품/서비스에 대한 고객충성도 연구

장경,민재영 한국산업경영시스템학회 2002 한국산업경영시스템학회지 Vol.25 No.3

This paper is mainly interested in customer‘s(fan's) royalty to professional sports in sports industry. The royalty is studied with the royalty to several products and a service, so that we can obtain the comparison between both the former and the latter royalty. Interested professional sports, products and service are baseball, basketball, soccer, beer, car, cola/cider, etc, and we will call each of them 'item'. The seven related hypotheses are considered. In hypotheses the dependent variable is royalty to nine items, and the independent variables are nine items, and customer's sex and major. For testing hypotheses, a questionaire is used, and reliability is checked with Cronbach's Alpha and correlation coefficients. For some items the royalty is significantly strong. Rather, even if some item has bad quality, it is found that customers can be royal to that item. We can identify some of those items through the results of this study. The strong significant results will be useful for the customer management. Additional studies are required for nonsignificant results which seems to be useful, and they are noted in the final part of the paper.

뇌졸중(腦卒中) 환자(患者) 중 편마비(偏痲痺) 환자(患者) 55명의 컴퓨터적외선체열진단과 증상(症狀)과의 비교 연구

국윤형,민재영,오상덕,임승만,라수연,백은탄,Koog, Yun-Hyung,Min, Jae-Young,Oh, Sang-Deog,Lim, Seung-Man,Ra, Su-Yoen,Paik, Eun-Tan 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5

Objectives : This study had been done to evaluate the effectiveness of DITI about hemiparesis in 55 patients with cerebral vascular disease who admitted to Dong-seo oriental hospital from November. 10. 1999 to October. 13. 2000, Methods : 55 stroke patients who had hemiparesis not only numbness nor quadriparesis were taken picture with DITI to measure infrared streamed from body's surface. And we compared DITI' results with hemiparesis to evaluate the effectiveness of DITl. Results : There was significant results between DITI and hemiparesis. Above 80%, we could find abnormality in the DITI pictures, which were exactly corresponding to symptom of hemiparesis. Conclusions : We thought that we can use DITI' results as a evaluation of stroke patients with hemiparesis.

프로 스포츠 및 일반제품/서비스에 대한 고객충성도 연구

장경,민재영 한국산업경영시스템학회 2002 한국산업경영시스템학회지 Vol.25 No.3