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민성,홍다혜,박수현 한국임상심리학회 2020 Korean Journal of Clinical Psychology Vol.39 No.1
Socially anxious individuals tend to disqualify positive social outcomes by attributing such outcomes to others rather than themselves. Previous research suggests that this tendency is a potentially important target of intervention. Thus, the present study aimed to examine the efficacy of cognitive bias modification (CBM) on attribution bias related to positive social outcomes among socially anxious individuals. A total of 159 undergraduate students were randomly assigned to the CBM or placebo group. Based on their level of social anxiety, participants were subsequently classified into either the high (n= 75) or low social anxiety groups (n= 18). Results showed that CBM was effective in reducing attribution bias related to positive social outcomes in socially anxious individuals. Social anxiety symptoms also diminished after the intervention. The findings of this study provide preliminary evidence regarding the efficacy of CBM for reducing attribution bias related to positive social outcomes and social anxiety
민성원,한지숙 한국식품영양과학회 2014 Preventive Nutrition and Food Science Vol.19 No.1
This study was designed to investigate the inhibitory effects of Polyopes lancifolia extract (PLE) on α-glucosidase activity, α-amylase activitiy, and postprandial hyperglycemia in streptozotocin (STZ)-induced diabetic mice. The results of this study revealed a marked inhibitory effect of PLE on α-glucosidase and α-amylase activities. The IC50s of PLE against α-glucosidase and α-amylase were 0.20 mg/mL and 0.35 mg/mL, respectively. PLE was a more effective inhibitor of α-glucosidase and α-amylase activities than acarbose, the positive control. The postprandial blood glucose levels of STZ-induced diabetic mice were significantly lower in the PLE treated group than in the control group. Moreover, PLE administration was associated with a decreased area under the curve for the glucose response in diabetic mice. These results indicate that PLE may be a potent inhibitor of α-glucosidase and α-amylase activities and may suppress postprandial hyperglycemia.
일 종합병원 정신과 입원환자에서의 Propranolol 사용(I)
민성호,박진환,신정호 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.1
This report was designed to investigate the propranolol use in a psychiatric in-patients unit. All of the patients who had admitted to the department of psychiatry of Yonsei University. Wonju Christian Hospital, from Jan. 1st to Dec. 31st 1990. were included in this investigation. The propranolol was prescribed in the 107 patients (69male patients and 38 female patients) among the total 147 patients. The results were as the followings : 1) The propranolol was prescribed in 23.9% of the 447 patients. 2) The patients whose initial daily dosage of the propranolol was between 40mg and 80mg. were 77.6% of the total patients, and the average dosage was 52.1±24.4mg. 3) The daily dosage of the prescribed propranolol ranged from 20mg to 440mg. The maximal dosage was 106.6±82.2mg/ 4) Schizophrenia was the highest diagnostic group(37.4%) among all DSM-III-R diagnostic distribution in the patients with the propranolol. 5) Symptom improvement was the main reason of limited-increase pattern of administration(46.7% ). 35 patients failed to continue propranolol use. 22 patients(62.9% ) among them had stopped propranolol use because of some kind of side effects. 6) Propranolol was effective in 80.4% of the patients for the target symptoms. 7) The target symptoms for the propranolol use were aggression, anxiety, akathisia, mania. psychosis and tremor. Akathisia(39 patients. 36.4%) was the most frequent reason of propranolol administration, the next was anxiety (30 patients. 28.0%). thereafter aggression(27 patients. 25.2%). The above 3 groups account for almost target symptoms(89.7%). 8) The maximal dosage for aggression was 191.9mg in average, and significantly higher than that for anxiety(98.3mg). akathisia(61.5mg) and tremor(56.0mg). 9) With the target symptoms of the propranolol use. the pattern of propranolol administration varied by one of three modes.