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내충격제 첨가에 따른 PPA 복합재료의 내충격 특성에 관한 연구
남궁지현(Jihyun Namkoong),하동헌(Dongheon Ha) 한국자동차공학회 2011 한국자동차공학회 학술대회 및 전시회 Vol.2011 No.11
To improve the competitiveness of PolyPhthalAmide glass fiber reinforced composite in engineering resin applications, it needs dimensional stability, stiffness, strength and impact resistance. In this study, impact modified PolyPhthalAmide blends were prepared by compounding PolyPhthalAmide with EPDM and SEBS-g-MAH. High impact strength can be achieved from SEBS-g-MAH compounding group. We confirmed that properties using application for EWGA gear. From the results of mechanical and tribologycal properties of the blends, SEBS-g-MAH acted as an impact modifier to increase the impact strength of the PolyPhthalAmide glass fiber reinforced composite. While EPDM acted as a wear-resistant modifier to decrease the friction coefficient and wear loss of the PolyPhthalAmide glass fiber reinforced composite.
서은혜,남궁지현,오충식,김성협,이승현 대한면역학회 2018 Immune Network Vol.18 No.3
Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells that show increased expression in cancer patients; however, the molecular mechanisms underlying their generation and function are unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer (BC), the presence and relevance of monocytic (Mo)-MDSCs are unknown. Here, we report for the first time increased chemokine and chemokine receptor production by Mo-MDSCs in BC patients. A clear population of Mo-MDSCs with the typical cell surface phenotype (human leukocyte antigen-antigen D related [HLA-DR]low/− CD11b+ CD33+ CD14+) increased significantly during disease progression. In addition, the chemokine receptor expression level on Mo-MDSCs in patients with invasive BC was the highest. Furthermore, different chemokine receptor expression patterns were noted in Mo-MDSCs between healthy controls (HC) and BC patients. Additionally, CD4 T cells proliferations were significantly decreased in the invasive BC groups compared with the HC group. However, the ductal carcinoma in situ (DCIS) group had no significantly compared with the HC group. Our data suggest that monitoring chemokine and chemokine receptor production by Mo-MDSCs may represent a novel and simple biomarker for assessing disease progression in BC patients.