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식도정맥류환자에서의 (食道靜脈瘤患者) 식도운동에 (食道運動) 관한 연구
김정용(Chung Young Kim),송인성(In Sung Song),최규완(Kyoo Wan Choi),정영화(Young Hwa Chung),이영상(Yung Sang Lee),전형식(Hyung Sik Jun) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.2
N/A Esophageal motility was studied in 14 control cases and 14 cases with esophageal varix, using low compliance pneumohydraulic capillary infusion system. 1) There was no difference in lower esophageal sphincter pressure between control and varix group (20.0+-l8.3mmHg and 19.8+- 5.7mmHg, respectively), but low esophageal peristaltic pressures were decr eased in varix group (51.0+-34.1mmHg) comparing with those in control group. (76.4+-16.4mmHg) (p<0. 05). The decrease of low esophageal peristaltic presure in varix group had no relation with varix grade or age distribution. 2) The lower esophageal peristaltic pressures were increased significantly after metoclopropamide administration in control (from 76.4+-16.4mmHg to 101.2+-21.6mmHg) and varix group (from 51.0+-34.1mmHg to 70.1>38.6mmHg), but the change of lower esophageal sphincter pressure was not significant.
원발성 (原發性) 간암의 (肝癌) 간절제가능성 (肝切除可能性) 판정에 있어서 간주사 (肝走査) , 복강경검사 (腹腔鏡檢査) 및 간혈관조영술의 (肝血管造影術) 비교
김정용(Chung Yong Kim),이효석(Hyo Suk Lee),정영화(Young Hwa Chung),김수태(soo Tae Kim) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1
N/A For the purpose of evaluating the predictive values for the resectability of primary liver cancer, the results of radionuclide liver scan, peritoneoscopy and hepatic angiography in 152 cases including 31 cases received laparotomy were reviewed and analyzed. The results were summarized as following: 1) The positive predictive value of radionuclide liver scan, peritoneoscopy and hepatic angiography was 58.9%, 77.3% and 84.2%, respectively, while the negative predictive value was 74.5% 96.9% and 96.3%, respectively. And the sensitivity of each method was 86.4%, 97.7% and 96.9% respectively, with the specificity of 39.8%, 71.3% and 81.8%, respectively. 2) Radionuclide liver scan was high in its sensitivity, but portal vein tumor emboli and metastasis to lymph nodes and adjacent organs couldnt be detected by this method, and therefore the specificity became low. Accordingly, the predictability for hepatic resection of this method was found to be poor. 3) Peritoneoscopy was more helpful than radionuclide liver scan and angiography in detecting metastasis to adjacent organs or small tumor nodules on the liver surface. However, portal vein tumor emboli and lesions located in the posterior surface of the liver couldn't be detected. 4) Hepatic angiography had difficulties in diagnosing diffuse type of metastasis to adjacent organs and lymph nodes. However, portal vein tumor emboli could be found and the accurate location and size of primary liver cancer could be evaluated, indicating that this test is a reliable and indispensible method for the evaluation of resectability. The results above showed that radionuclide liver scan, peritoneoscopy and hepatic angiography were indispensible and complementary each other in judging resectability of primary liver cancer and should be performed in that order to select candidates for laparotomy.
한국인 급성 Virus 성 간염열에 있어서의 Hepatitis - Associated Antigen 에 관한 임상적 관찰
김정용 ( Chung Yong Kim ),강영민 ( Young Min Kang ) 대한내과학회 1972 대한내과학회지 Vol.15 No.6
Hepatitis-associated antigen, HAA, was measured by the modified method of micro-Ouchterlony double diffusion using agarose gel in phosphate buffered saline-EDTA, pH 7. 8, in the patients with acute viral hepatitis to evaluate the occurrence of HAA among Ko
TIRE-LII 기법을 이용한 매연 입자 크기에 관한 수치적 연구
김정용(Jeong Yong Kim),이종호(Jong Ho Lee),정동수(Dong Soo Jeong),전충환(Chung Hwan Jeon),장영준(Young June Chang) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.11
Temporal behavior of the laser induced incandescence (LII) signal is often used for soot particle sizing, which is possible because the cooling behavior of a laser heated particle is dependent on the particle size. In present study, LII signals of soot particles are modeled using two non-linear coupled differential equations deduced from the energy- and mass-balance of the process. The objective of this study is to see the effects of particle size, laser fluence on soot temperature characteristics and cooling behavior. Together with this, we focus on validating our simulation code by comparing with other previous results. Results of normalized LII signals obtained from various laser fluence conditions showed a good agreement with that of Dalzell and Sarofim's. It could be found that small particles cool faster at a constant laser fluence. And it also could be observed that vaporization is dominant process of heat loss during first 100ns after laser pulse, then heat conduction played most important role while thermal radiation had little influence all the time.
Dubin - Johnson 증후군 (증후군) 10예에 대한 임상적 (임상적) 고찰
윤용범,이원표,김정용 ( Yong Bum Yoon,Won Pyo Lee,Chung Young Kim ) 대한소화기학회 1980 대한소화기학회지 Vol.12 No.1
The Dubin-Johnson Syndrome is characterized by chronic, mild, predominantly conjugated hyperbilirubinemia with a blcak liver and pigmentation of parenchymal liver cell. The disor- der result from an inherited abnormality in the excretion of various non-bile salt organic anion from the liver cell into the bile. It is benign non-progressive and not associated with any form of chronic hepatic or biliary tract disease. The diagnosis of the Dubin-Johnson synd- rome is established by secondary rise in BSP retension test and needle biopsy of the liver. The important consideration in managing patient with this disorder are the reassurrance that the abnormality is benign and leads to no disability or reduction in life expectancy and the avoidance of unnecessary biliary tract surgery. Clinical observation was made on 10 cases of Dubin-Johnson Syndrome admitted to department of internal medicine, Seoul Xatio- nal University Hospital from 1969 to 1979. The following results are obtained 1. The male to female ratio was 6: 4 and the majority of the caes are in 'rd decale 2. There avere 3 cases of jaundice on family history and 2 cases ,vere 'orother nd sister relationship The chief complaints on admission were in order of jaund!ce, Satigue, rigiit upper abd- ominal oain and darl- urine. Hepatomogaly was observed in 5 cases, but there was no case of splenomegaly The average serum total biliubin level was Z. 98+ l. 29mg/100ml and the average serum conjugated bilirubin level vas l. 7p0. 94 mg/lpQml. Other liver function tests revealed normal v lues. 6. HBsAg and aFP test were performed in 5 cases and the results wcre negative in all cases Oral cholecystography was performed in 6 cases and the gallbladder was visualized in 8 cases, suggesting that the important non-visualization of gall-bladder on oral cholecy- stography for the diagnosis of the disorders ought to be reconsidered.
십이지장궤양환자에서의 (十二指腸潰瘍) 위배출속도 (胃排出速度)
송인성(In Sung Song),김정용(Chung Yong Kim),이효석(Hyo Suk Lee),송영욱(Yeong Wook Song),이영상(Young Sang Lee) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1
N/A Gastric emptying rate was studied with the acetaminophen method in 21 normal volunteers and 17 active duodenal ulcer patients. As an indicator of gastric emptying rate, the serum acetaminophen concentration was measured by dye method at 0, 30, 60 90, 120, 180 minutes after ingestion of 50 ml of water with l. 5g of acetaminophen. In normal subjects, the serial mean serum concentrations of acetaminophen were 16.6, 19.3, 20.5, 16.8, 13.0 ug/ml, respectively, and in the active duodenal ulcer patients the concentrations were 19.1, 20.2, 18.9, 16.4, 11.1 ug/ml, respectively. The peak serum concentretion seemed to appear earlier in the ulcer patients, and mximum serum concentrations were 24.2+-4.3 ug/ml in the normal subjects and 24.1+-8.9 ug/ml in the active duodenal ulcer patients, both of which, however, were neither statistically significant, indicating that there was no significant acceleration of gastic emptying rate in patients with active duodenal ulcer.
김정용,이상준,정규철 중앙대학교 의과대학 의과학연구소 1990 中央醫大誌 Vol.15 No.2
The effects of cadmium and protective effects of ascorbate, diethyldithiocarbarnate (DDTC), glutathione and α-tocopherol on hydrogen peroxide production, catalase and Na^+, K^+-ATPase activities in kidney of rats acutely intoxicated by cadmium were investigated. A single dose of 5mg/kg CdCI_2 were given to all Sprague-Dawley male rats by intraperitoneal injection. In addition, 1 mM/kg ascorbate in Cd + ascorbate-treated group, 500 mg/kg DDTC in Cd + DDTC-treated group, 1 mM/kg glutathione in Cd + glutathione-treated group and 0.5 mM/kg α-tocopherol in Cd + α-tocopherol-treated group were given intraperitoneally 60 min after the cadmium treatment. The saline-treated group was treated with saline only. Rats of each group were sacrificed by decapitation 48 hours after the cadmium treatment. The cadmium concentration in kidney increased with that in blood both in saline and experimental groups. Average cadmium concentrations in blood and kidney of Cd-treated rats were much higher than those in saline-treated group, but no differences were found in average cadmium concentrations in blood and kidney among Cd-treated, Cd + ascorbate-treated, Cd + DDTC-treated, Cd + glutathione -treated and Cd + α-tocopherol-treated groups. In Cd-treated group, hydrogen peroxide production and catalase activity of kidney homogenates was increased but Na^+, K^+-ATPase activity was decreased. Glutathione inhibited cadmium-induced hydrogen peroxide production most effectively. Ascorbate, DDTC and α-tocopherol also inhibited cadmium-induced hydrogen peroxide production. Catalase activity was inhibited in ascorbate-and glutathione-treated groups more than that in Cd-treated group, and no difference was found in catalase activities among Cd + DDTC-treated and Cd + α-tocopherol -treated groups. Inhibition of Na^+, K^+-ATPase activity induced by cadmium was diminished by simultaneous administration of ascorbate, DDTC, glutathione or α-tocopherol. In normal and experimental groups, hydrogen peroxide production increased with increasing cadmium concentrations and the Na^+, K^+-ATPase activity decreased with increasing hydrogen peroxide productions. These results suggest that inhibition of Na^+, K^+-ATPase activity caused by hydrogen peroxide in cadmium intoxicated rats may play a part in cadmium induced renal functional injury. Ascorbate, DDTC, glutathione and a-tocopherol exhibit protective effects against cadmium mediated inhibition of Na^+, K^+-ATPase activity and these effects brought by inhibition of cadmium-induced hydrogen peroxide production.