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김병훈(Kim Byeong Hun),김재훈(Kim Jai-Hoon) 한국통신학회 2021 한국통신학회 학술대회논문집 Vol.2021 No.11
본 논문에서는 스마트팩토리 보안위협을 식별하고, 보안위협을 대응하기 위한 보안 관리체계의 필요성을 제시한다. 기존 보안관리체계에서의 장점을 통하여 스마트팩토리에 적합한 보안관리체계를 제시하고 보안관리체계 도입 후 보안위협에 대해 정략적 평가를 진행한다. 이를 통하여 국내 스마트팩토리 보안인식과 보안 활성화에 도움을 주는데 기여하고자 한다.
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감마선 조사기술 이용 극한환경에서도 취식 가능한 수정과 제조에 관한 연구
박재남,이주운,김재훈,김관수,한규재,설민숙,이현자,변명우,Park, Jae-Nam,Lee, Ju-Woon,Kim, Jae-Hun,Kim, Kwan-Soo,Han, Kyu-Jai,Sul, Min-Sook,Lee, Hyun-Ja,Byun, Myung-Woo 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.5
본 연구는 극한환경에서도 취식이 가능한 수정과를 제조하고자 감마선 조사기술을 이용하여 수정과의 미생물학적 안전성을 확보한 후 이에 따른 품질을 평가하였다. 감마선 조사의 효과를 확인하기 위해 수행한 세균 발육시험에서 수정과의 멸균을 위한 최소선량은 약 4.5 kGy인 것으로 확인되었다. 그러나 관능평가 결과 수정과의 품질은 감마선 조사선량이 증가할수록 감소하는 것으로 나타났으며, 특히 수정과 멸균을 위해 필요로 하는 4.5 kGy 이상의 선량에서는 모든 평가항목에서 관능적 품질이 급격히 저하되었다. 품질개선 목적으로 포장방법에 따른 변화를 확인한 결과 함기포장에 비해 진공 또는 질소치환 포장 시 수정과의 품질 증진에 효과적인 것으로 나타났다. 또한 vitamin C와 cinnamic aldehyde를 첨가한 후 진공포장과 병용처리 시 감마선 조사에 의한 품질저하 방지가 가능하여 감마선을 조사하지 않은 시료와 동일한 품질을 갖는 수정과의 제조가 가능하였다. This study was conducted to develop the method for the safe supply of Sujeonggwa (cinnamon flavored persimmon punch) in severe environments such as space, desert or deep sea, by the combined treatment of gamma irradiation with other food technologies. Commercially prepared Sujeonggwa powder could be sterilized at 4.5 kGy or above doses. However, sensory characteristics of gamma-irradiated Sujeonggwa decreased depending upon the dose. The combined treatment of vacuum packaging with the addition of vitamin C and cinnamic aldehyde in Sujeonggwa powder could minimize the change of sensory qualities induced by ionizing irradiation.
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신성고혈압 흰쥐에서 5-HT에 의한 혈관수축에 있어 Tyrosine Kinase의 역할
염철호(Cheol Ho Yeum),전제열(Jae Yeoul Jun),윤평진(Pyung Jin Yoon),김재훈(Jai Hun Kim),김종승(Jong Seung Kim),이정희(Jeong Hoe Liee) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.1
N/A Tyrosine kinases have been implicated in vascular smooth muscle cell proliferation and contraction. The involvement of tyrosine kinases in 5-hydroxytryptamine (5-HT)-induced contractile response of the isolated aorta was examined in two-kidney, one clip (2K1C) hypertensive rats, 2141C hypertension was made by constricting the left renal artery and age-matched control rat received sham treatment. Thoracic aortic rings denuded of endotheliurn were mounted in tissue bath, for measurement of isometric contractile force. The putative tyrosine kinase inhibitor, genistein, shifted concentration-response curves to 5-HT toward the right in control rats The isometric force generation induced by 5-HT was also inhibited by genistein in aortic rings from 2K1C: hypertensivc rats, however genistein did not affect on the high concentration of 5-HT in hypertensive rat ;. Genistein-induced relaxations were more attenuated in aortae from hypertensive rats than those from control Genistein had no effect on contrartcion elicited by the direct protein kinase C activator, phorbol 12, 13 dibutyrate (PDBu) either in 2KlC hypertensive or in control Group. These findings indicate that genistein-sensitive tyrosine kinases paeticipate in 5-HT-induced contraction of rat aortic smooth muscle, of which role is apparent in 2K1C: hypertension.
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중추에서 Prostaglandin계가 Renin-angiotensin System에 미치는 영향
최영태,김종승,문성호,오형균,김재훈,전제열,염철호,윤평진 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.1
Role of prostaglandins on the renin-angiotensin system in the central nervous system was examined in normotensive and 2-kidney, 1 clip (2K1C) hypertensive rats. The experiment was done under thiopental (50 ㎎/㎏, IP) anesthesia. Captopril and indomethacin were injected into the right lateral cerebral ventricle. Arterial blood pressure and heart rate were recorded from the femoral artery. Intracerebroventricular (ICV) captopril (1 ㎎) caused a decrease in mean arterial pressure in both normotensive and 2K1C hypertensive rats. The depressor response to captopril was more sensitive in hyper-tensive rats than in normotensive rats. Indomethacin treatment (ICV, 200 ㎎) altered the depressor response to captopril neither in normotensive nor in hypertensive rats. These results suggest that the cardiovascular effect of renin-angiotensin system in the central nervous system may not be mediated via prostaglandin systems in normotensive and 2KlC hypertensive rats.
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흰쥐에서 Nitric Oxide 합성 억제가 Bradykinin의 승압 및 감압효과에 미치는 영향
윤평진,이종은,문성호,염철호,전제열,양민준,김재훈 대한신장학회 1998 Kidney Research and Clinical Practice Vol.17 No.5
Bradykinin has been known to elicit a pressor effect when administered centrally, and a depressor effect when administered peripherally. The present study was aimed at investigating whether the blood pressure response to bradykinin is dependent on the endogenous generation of nitric oxide (NO). Effects of NG-nitro-L-arginine methyl ester (L-NAME) on the pressor and depressor responses to intracerebroventricularly and intravenously injected bradykinin (5nmol/rat), respectively, were examined in anesthetized rats. Neither the pressor response nor the depressor response was affected by acute parenteral treatment with L-NAME. The pressor and depressor effects of bradykinin were also noted in rats chronically supplemented with L-NAME in drinking water for 4 weeks. Bradykinin caused a relaxation of the isolated thoracic aorta in vitro, which was not affected in the presence of L-NAME. However, bradykinin failed to cause a relaxation of the aorta isolated from rats chronically treated with L-NAME. These findings suggest that endogenous generation of NO may not completely account for the blood pressure responses to bradykinin in rats.
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