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인후두위산역류증(Laryngopharyngeal Reflux: LPR)의 치료에 대한 RabeprazoleSodium(Parietd)의 임상효과와 안전성 검토
정광윤,전병선,고상현,권기환,권순영,권중근,김동영,김상철,김성완,김영모,김영호,김윤환,김장묵,Jung, K.W.,Jun, B.S.,Ko, S.H.,Kwon, K.H.,Kwon, S.Y.,Kwon, J.K.,Kim,, D.Y.,Kim,, S.C.,Kim,, S.W.,Kim,, Y.M.,Kim,, Y.H.,Kim,, Y.H.,Kim,, J.M. 대한기관식도과학회 2004 大韓氣管食道科學會誌 Vol.10 No.2
Background and objective : Rabeprazole is a new generation proton pump inhibitor, which has a rapid onset after first dose, predictable efficacy in all patients regardless of CYP2C19 genotype status, and less nocturnal acid breakthrough. The aim of the study is to investigate clinical efficacy and safety of rabeprazole sodium (Pariet 10mg qd)when administered once daily to patients with laryngopharyngeal reflux(LPR) disease. Methods : Among the patients who had visited the Department of Otolaryngology, those with LPR symptoms, had undergone laryngoscopy. Symptoms and endoscopic laryngeal sings were recorded initially, at 1 month, 2 months, 3 months, and more than 3 months, All patients were evaluated for clinical efficacy on the basis of symptom scores, reflux finding score(RFS), and side effects. Results : In general, most symptom scores and RFS improved over the time. Efficacy of the Pariet on LPR-related symptoms were $63.2\%,\;77.5\%,\;78.7\%,\;and\;90.9\%$ before 4 weeks, 4 to 8 weeks, 8 to 12 weeks, and after 12 weeks respectively. Efficacy on the RFS were $61.8\%,\;78.4\%,\;82.9\%,\;and\;85.5\%$ before 4 weeks, 4 to 8 weeks, 8 to 12 weeks, and after 12 weeks respectively. Pariet was well tolerated and was associated with few drug-related side effects. Conclusion Because of its efficacy and safety, Pariet may prove to be an alternative to currently available proton pump inhibitors.
산란계의 에너지 요구량에 관한 연구 에너지 수준이 산란계의 산란능력 및 품종별 산란능력에 미치는 영향
암병홍,김윤환,안동원 ( B . H . Ahn,Y . H . Kim,D . W . Ahn ) 한국축산학회 1980 한국축산학회지 Vol.22 No.2
To investigate the effect of the dietary energy levels on the laying performance of laying hens and the laying performance by strains of laying hens this experiment was carried out for 350 days from 151 through 500 days of age of laying hens with Chuksi 735. Rhode Island Red X White Leghorn. New Hamp-shire X Rhode Ialand Red and Shaver Isoprotein level(15% crude protein) and 3 levels of dietary energy that is ME 2850㎉/㎏ (energy 100%) 2565㎉/㎏ (energy 90%) and 2280㎉/㎏ (energy 80%) were splited into 5 replication. 4 strains(Chuksi 735, RIF X WL. NH X RIR, Shaver) of laying hen were evenly allocated to a dietary energy level. A total of 600 laying hens were used in this experiment and 50 laying hens were allocated to each strain. The results obtained were as follows. 1. Hen-day egg production rate of energy 100%, 90% and 80% was between 65 and 67% on an average and decreased as the dietary energy levels decreased. However there were no statistical differences between treatments on the hen-day egg production. In the hen-day egg production by strains of laying hen. Shaver produced 73% of egg on the basis of the hen-day egg production and was greatly (P$lt;0.01) highest among the strains of laying hen 67% of Chuksi 735 was next and significant (P$lt;0.01) differences were found out between strains of laying hen. 2. Egg weight from hens on 3 energy levels of 100%, 90% and 80% was 57.5g on an average and was not affected by the energy levels. In the egg weight by strains of laying hen weight of egg produced by Shaver and Chuksi 735 was significant (P$lt;0.05) heavier than that of egg produced by cross strains. 3. Diet intake was progressively decreased as the energy levels increased. Hen fed energy 100% consumed significant (P$lt;0.05) less feed than hens on energy 80%. In the strains of laying hen Shaver and Chuksi 735 of light body weight consumed significant (P$lt;0.01) less feed than cross strains of heavy body weight. 4. Feed required per ㎏ egg production generally was 3.12㎏ to 3.45㎏ and was progressively higher as energy levels decreased. However, there were no significant differences between treatments. In the strains of laying hen, Shaver and Chuksi 735 of light body weight required significant (P$lt;0.01) less feed per ㎏ egg production than cross strains of heavy body weight. 5. In the hen-housed average egg production by strains of laying hen, Shaver produced 247 of egg and was greatly (P $lt;0.01) highest among the strains of laying hen and 231 of egg of Chuksi 735 was next. 6. In the first day of 50% egg production by strains of laying hen, Shaver and Chuksi 735 were slightly (P$lt;0.05)earlier than cross strains of laying hen. 7. In the economical analysis, crude income per hen was lower with hens on high energy level than those on low energy. 8. Therefore according to this experiment, it may be concluded that laying performance was not affected by the dietary metabolizable energy levels between 2565Kcal and 2850Kcal per ㎏ of feed. In the strains of laying hen. Shaver was the highest for the laying performance and next for Chuksi 735.
조사료로 볏짚 단사와 볏짚과 청초급여가 한우육성 비육우의 성장에 미치는 영향
안동원,김윤환,안병홍 ( D . W . Ahn,Y . H . Kim,B . H . Ahn ) 한국축산학회 1984 한국축산학회지 Vol.26 No.4
This experiment was conducted to investigate the performance of Korean native bulls fed rice straw and forages or rice straw only as a roughage sources during the growing period of 180 days. The results obtained are summarized as follows: In the body gain, animals fed rice straw and forages and those fed rice straw only had 182.6㎏ and 157.2 ㎏, respectively. Thus, animals fed rice straw and forages are greater than those fed rice straw only. Feed efficiencies are 7.66 for animals fed rice straw and forages and 8.12 for those fed rice straw only. Animals fed rice straw and forages as a roughage sources were better than those fed rice straw only. There are significant differences in the body gain and feed efficiency between treatments (P$lt;0.01). Feed intake was much greater for animals fed rice straw and forages than those fed rice straw only. It can be concluded that forage would increase palatability and obserbed that good roughages are closely related to the feed intake. In the change of body type, the height of hip cross and fore shank circumference were significantly (P$lt;0.01) longer for animals fed rice straw only than those of animals fed rice straw and forages. Rump length was longer for animals fed rice straw and forages than those animals fed rice straw only and there was significant difference between treatments (P$lt;0.05). However, withers height, body length, heart girth, chest width, girth of chest and abdomen, chest width and pin bone width were not statistically significant between treatments.