미래 의학교육을 위한 의과대학 신축의 건축디자인 방향성

김남주,Kim, Namju 연세대학교 의과대학 2015 의학교육논단 Vol.17 No.3

This literature review explores relevant research and evaluation on pedagogy and physical learning spaces. This study also is intended to encourage discussion among stakeholders on the best medical school developments, in light of emerging learning trends relevant to their institutions. The study has revealed that new environments for learning are being designed or reshaped in response to changing pedagogical approaches, to incorporate new information technology, and to accommodate the changing abilities of new generations of learners. Formal teaching spaces for large groups with a 'sage on a stage' are becoming less common than smaller lecture rooms, although classrooms form a large component of universities and will continue to dominate in the future. However, the traditional layout of these spaces is being transformed to incorporate multiple learning modes. Classrooms should be profound places of revelation and discovery. A well-designed space has the ability to elevate discourse, encourage creativity, and promote collaboration. Within the classroom walls, a learning space should be as flexible as possible, not only because different teachers and classes require different configurations, but because in order to fully engage in learning, students need to transition between lectures, group study, presentations, discussions, and individual work time.

치아 자가진단 및 관리를 위한 통합 제품서비스 플랫폼 연구

김남주(Kim, Namju),원세현(Won, Sehyeon),박승민(Park Seungmin) 한국디자인학회 2019 한국디자인학회 학술발표대회 논문집 Vol.2019 No.5

A proposal of classification and evaluation method of pollution vulnerabilities by a highly permeable terrain in Jeju Island

김남주(Namju Kim),유영권(Young Kwon You),전병추(Byeongchu Jeon),김대성(Daesung Kim) 대한지질학회 2019 지질학회지 Vol.55 No.2

본태눈꺼풀연축 환자에서 Letibotulinum Toxin A의 유효성과 안전성 평가

김지현(Ji Hyun Kim),정도훈(Doh Hoon Chung),김성은(Sung Eun Kim),백지선(Ji-Sun Paik),김남주(Namju Kim),나태윤(Tae Yoon La),손준혁(Jun Hyuk Son),안희배(Hee Bae Ahn),양재욱(Jae Wook Yang),우경인(Kyung In Woo),유혜린(Helen Lew),윤진숙(Jin S 대한안과학회 2020 대한안과학회지 Vol.61 No.3

목적: 본태눈꺼풀연축 환자를 대상으로 보툴렉스Ⓡ의 유효성 및 안전성을 평가하고자 하였다. 대상과 방법: 총 15개 기관에서 본태눈꺼풀연축 환자 250명이 본 임상시험에 등록되었으며, 이 중 220명의 대상자가 본 시험을 완료하였다. 대상자는 투여 후 4주와 16주 시점에 방문하여 유효성 및 안전성 평가를 시행하였으며, 투여 4주 시점에 일차 유효성 평가가 가능했던 240명이 intention-to-treat (ITT) 분석군에 포함되었다. 유효성 평가는 ITT 분석을 기본으로 하였고, Jankovic Rating Scale(JRS), 기능장애척도, 시험자 반응 평가, 삶의 질 평가를 이용하였으며, 안전성 평가는 이상반응에 대한 분석을 이용하였다. 결과: ITT군에서 일차 유효성 평가변수인 베이스라인 대비 보툴렉스?? 투여 4주 후 JRS 총점의 평균 변화량은 통계적으로 유의한 감소를 나타내었으며(p<0.0001), 유사제제와 비교 시에 비열등함을 확인하였다. 이차 유효성 평가변수 중 베이스라인 대비 투여 16주 후 JRS 총점의 평균 변화량과 베이스라인 대비 투여 4주 및 16주 후 기능장애 평가점수 총합의 평균 변화량이 통계적으로 유의한 감소를 보였다(p<0.0001 for all). 시험약을 투여받은 249명의 대상자 중 44명(17.6%)에서 76건의 이상반응이 발생하였으나, 심각한 이상반응을 보인 대상자는 없었다. 결론: 보툴렉스?榮? 본태눈꺼풀연축 환자에서 효과적이고 안전하게 사용될 수 있는 약제로 사료된다. Purpose: To evaluate the efficacy and safety of BOTULAXⓇ in subjects with essential blepharospasm. Methods: In this study, a total of 250 subjects with essential blepharospasm were enrolled at 15 investigational sites and a total of 220 subjects completed the study. The efficacy and safety were evaluated at weeks 4 and 16 after treatment compared with baseline. In total, 240 subjects were enrolled, treated with the investigational product, and evaluable for the primary efficacy assessment at week 4 after treatment; these subjects were included in the intention-to-treat (ITT) population. With the ITT set as the main efficacy set, efficacy assessment included Jankovic rating scale (JRS), functional disability score, investigator evaluation of global response and quality of life. Safety assessment including the incidence of adverse events was also performed. Results: In terms of the primary efficacy endpoint (i.e., change in JRS total score at week 4 after treatment from baseline [ITT set]), mean change indicated a statistically significant reduction (p < 0.0001) and demonstrated the non-inferiority of the test drug to similar drugs. In terms of the secondary efficacy endpoints, mean change in JRS total score at week 16 after treatment and mean change in functional disability score at weeks 4 and 16 after treatment both exhibited a statistically significant reduction compared with baseline (p < 0.0001 for all). Among the 249 subjects treated with the investigational product in this study, 44(17.67%) experienced 76 treatment emergent adverse events but no serious adverse events were observed. Conclusions: Based on the study results, BOTULAXⓇ is considered to be an effective and safe treatment for essential blepharospasm.

자가귀연골이식을 이용한 아래눈꺼풀뒤당김 교정술

윤창호,김남주,이민정,정호경,반민섭,곽상인,Changho Yoon,Namju Kim,Min Joung Lee,Hokyung Choung,Min Seop Pahn,Sang In Khwarg 대한안과학회 2011 대한안과학회지 Vol.52 No.2

Purpose: To evaluate the surgical results of lower eyelid retraction using autologous ear cartilage graft. Methods: Fifty patients (54 eyes) who received surgical correction of lower eyelid retraction by lower eyelid retractors and conjunctiva recession from the tarsal plate with autologous ear cartilage grafts from March 2002 to July 2010 were evaluated. Medical records were reviewed and clinical characteristics, surgical outcomes, and postoperative complications were analyzed retrospectively. Results: The use of prosthesis due to anophthalmos or microphthalmos (22 eyes) was the most common cause of lower eyelid retraction. The mean postoperative follow-up period was 16.6 months (1-98 months). Lower eyelid retraction was successfully corrected in 52 of 54 eyes. Postoperatively, 2 cases of corneal erosions, 1 case of conjunctival erosion, and 2 pyogenic granulomas developed. Corneal and conjunctival erosions resolved with conservative management and granulation tissues were removed by excision. Conclusions: Correction of lower eyelid retraction using autologous ear cartilage graft is an excellent surgical procedure with low complication rates for eyelid retraction of various etiologies. J Korean Ophthalmol Soc 2011;52(2):136-140

눈꺼풀테에 발생한 연골모양땀관종 1예

안성준,김남주,정호경,곽상인,Seong Joon Ahn,Namju Kim,Ho Kyung Choung,Sang In Khwarg 대한안과학회 2011 대한안과학회지 Vol.52 No.7

Purpose: To report a case of chondroid syringoma that involved the eyelid margin, was accompanied by cilia loss, and required differential diagnosis with other malignant eyelid masses. Case summary: A 46-year-old woman presented with a recurrent mass in the right lower eyelid margin, which was observed 10 years earlier, where incision and curettage had already been performed twice. The mass was neither tender nor ulcerated, was brighter in color than the neighboring skin, and had a smooth surface with cilia loss. The pathologic findings obtained from an incisional biopsy were compatible with a dermoid cyst. Full-thickness excision of the eyelid mass and direct closure were subsequently performed. The pathologic diagnosis after excisional biopsy was chondroid syringoma because cystic structures in the chondroid stroma were observed. J Korean Ophthalmol Soc 2011;52(7):859-862

눈꺼풀에 발생한 피지낭종 1예

김태준,김남주,박효진,정호경,곽상인,Tai Jun Kim,Namju Kim,Hyo Jin Park,Ho-Kyung Choung,Sang In Khwarg 대한안과학회 2012 대한안과학회지 Vol.53 No.7

Purpose: To report a case of eyelid steatocystoma. Case summary: A 65-year-old woman presented with a mass around the punctum in the right lower eyelid margin, which developed several years earlier. The mass was a light yellowish cystic nodule and there were no other ocular abnormalities. Under local anesthesia, the mass was completely excised. Histopathologic examination showed a cyst surrounded by stratified squamous epithelium and a sebaceous duct which entered the hair follicle, compatible with the diagnosis of steatocystoma. Conclusions: Steatocystoma should be considered as a differential diagnosis of a solitary cystic eyelid tumor. J Korean Ophthalmol Soc 2012;53(7):1027-1029

눈꺼풀에 발생한 유두상 땀샘낭샘종 1예

이대승,김남주,박효진,정호경,곽상인,Dae Seung Lee,Namju Kim,Hyo Jin Park,Ho-Kyung Choung,Sang In Khwarg 대한안과학회 2012 대한안과학회지 Vol.53 No.7

Purpose: To report a case of syringocystadenoma papilliferum that presented as an eyelid nodule. Case summary: A 37-year-old woman presented with a mass around the punctum in the right lower eyelid margin, which had developed several years earlier and was increasing in size. The mass was a light pinkish nodule consisting of a few smooth-surface papillary lobules. The pathologic findings of the specimen obtained from a shaving biopsy showed a papillary projection which was covered with epithelium and communication with duct-like structures showing glandular configuration in the deep portion of the lesion. EMA-positive cells were found at the invaginated epithelium, implying a glandular epithelial origin. GCDFP-15-positive cells were found in the deep portion of the lesion, implying apocrine differentiation. The findings were compatible with syringocystadenoma papilliferum. Conclusions: Syringocystadenoma papilliferum should be considered as a differential diagnosis of a solitary eyelid tumor. J Korean Ophthalmol Soc 2012;53(7):1023-1026

제한사시를 동반한 갑상샘눈병증 환자에서 골드만압평안압계와 토노펜의 안압측정치 비교 분석

김준식(Jun Sik Kim),이은지(Eun Ji Lee),김남주(Namju Kim,) 대한안과학회 2017 대한안과학회지 Vol.58 No.6

목적: 제한사시를 동반한 갑상샘눈병증 환자에서 골드만압평안압계로 측정한 안압과 TonoPen 접촉안압계로 측정한 안압을 비교하 고, 그 차이에 영향을 미치는 인자를 분석하고자 하였다. 대상과 방법: 갑상샘눈병증으로 진단받은 50명 50안에서 골드만압평안압계와 TonoPen 접촉안압계로 각각 안압을 측정하여 비교하 였다. 안구운동제한 정도, 사시각, 안구돌출계검사, 중심각막두께, 굴절오차, 갑상샘호르몬 수치 등을 포함하여 두 안압계의 안압측정치 차이에 영향을 주는 인자들을 분석하였다. 결과: 갑상샘눈병증 환자에서 골드만압평안압계는 Tonopen 접촉안압계에 비해 안압을 높게 측정하는 경향을 보였고(각각 16.1 ± 4.7, 13.8 ± 4.5 mmHg, p<0.001), 안구의 수직운동제한 정도가 심할수록 그 차이가 더 큰 것으로 나타났다(p=0.037). 두 안압계의 안압측정치 차이의 절대값은 안구의 수직운동제한 정도가 심할수록(p=0.027), 수직방향 사시각이 클수록(p=0.021), 그리고 중심각막 두께가 두꺼울수록(p≤0.031) 더 큰 것으로 나타났다. 결론: 안구의 수직운동제한을 동반한 갑상샘눈병증 환자에서 안압 측정 시, 안압계 종류에 따른 측정치의 오차를 고려해야 하겠다. Purpose: To compare the intraocular pressure (IOP) measured using Goldmann-applanation tonometry (GAT) and Tonopen ?? tonometry and to evaluate the factors influencing the measurement difference in patients with thyroid-associated ophthalmopathy (TAO)-related restrictive strabismus. Methods: In 50 eyes of 50 patients who were diagnosed with TAO, IOP measurements were taken using both GAT and a Tonopen ?? and were subsequently compared between the devices. Factors influencing the measurement difference between the devices were determined, including the restriction of eyeball movement, eyeball deviation, exophthalmometry, central corneal thickness, refractive errors, and blood thyroid hormone levels. Results: In the TAO patients, the GAT-measured IOP was higher than for Tonopen ?? (16.1 ± 4.7 vs. 13.8 ± 4.5 mmHg, respectively, p < 0.001). As the restriction of vertical eyeball movement increased, the IOP difference between the devices also increased (p = 0.037). The absolute IOP difference between the devices was positively correlated with restrictions in vertical eyeball movement (p = 0.027), degree of vertical strabismus (p = 0.021), and central corneal thickness (p ≤ 0.031). Conclusions: In patients with TAO accompanying vertical eyeball movement restriction, potential errors in IOP measurements should be considered between the different IOP-measuring devices.

개방형 지열 시스템에 사용된 지하수 내 미생물종 모니터링: 예비연구

박영윤(Youngyun Park),김남주(Namju Kim),권만재(Man Jae Kwon),이진용(Jin-Yong Lee) 대한지질학회 2014 대한지질학회 학술대회 Vol.2014 No.10