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      • KCI등재

        접촉성 Nd-YAG 레이져와 봉합사를 이용한 토끼의 미세난관 문합술에서 난관의 소통성과 임신율 비교

        김진홍(Jin Hong Kim),류순원(Sun Won Yoo),조현희(Hyun Hee Jo),김현영(Houn Young Kim),김미란(Mi Ran Kim),권동진(Dong Jin Kwan),임용택(Yong Taik Lim),김장흡(Jang Heub Kim),이진우(Jin Woo Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.3

        N/A Objective : Many different methods have been undertaken to increase the success rate of tuboplasty. The development of a new generation of surgical lasers has offered a possibility for the practical use of the laser technique in microsurgical fields. In gynecology, the laser beam has been reported to be a precise instrument for successful tubal surgery with minimal bleeding and postoperative reaction. The authors studied the effect of the infrared laser beam in the area of tubal reanastomosis. Methods : To compare tubal patency, pregnancy rate, and histologic difference in site of anastomosis, total 120 tubes of 60 rabbits were used for experimental tuboplasty. The study groups were divided according to the kinds of reanastomosis methods. Group I : 1 layer(right tube) and 2 layer(left tube) anastomosis without using splint, group II : 1 layer(right tube) and 2 layer(left tube) anastomosis with using splint, group III : reanastomosis using laser with splint(III-b) and without splint(III-a). Results : 1. The infiltration of inflammatory cell were observed in all group by optical microscopic examination. Group II revealed more fibrotic change and inflammatory cell without significant statistical difference and there was no significant difference between left and right tubes in each group. 2. The tubes of group II were significantly more patent(75%) than that of group I(50%). Especially the patency of group III performed Nd-YAG laser with splint was the highest(90%). 3. The pregnancy rates in groups without splint were 40%(one layer without splint, group I-right tube), 60%(two layer without splint, group I-left tube), 30%(Nd-YAG laser without splint, group III-a), were significantly lower than that of group with splint, 60%(one layer with splint, Group II-right tube), 60%(two layer with splint, Group II-left tube), 80%(Nd-YAG laser with splint, Group III-b). Especially the group IIIb showed the hightest pregnancy rate(80%). Conclusion : From the above results, it is considered that the tubal reanastomosis using splint and Nd-YAG laser will improve the pregnancy rate and could be the procedure of choice in the future.

      • SCOPUSKCI등재

        임신능이 확인된 가임 여성에서의 Deciduosis의 유병율

        김미란,유영옥,노덕영,류순원,권동진,김장흡,김진홍,임용택,김은중,정재근,이진우,Kim, Mee-Ran,Lew, Young-Oak,Ro, Duck-Yeong,Ryu, Sun-Won,Kwan, Dong-Jin,Kim, Jang-Heub,Kim, Jin-Hong,Lim, Yong-Taik,Kim, Eun-Jung,Jung, Jae-Keun,Lee, Jin-Woo 대한생식의학회 2000 Clinical and Experimental Reproductive Medicine Vol.27 No.4

        Objective: Extrauterine formation of decidua of stromal cells has been well described, particularly in the cervix and ovary. The apparent hormonal mechanisn of this phenomenon suggestes a relationship to endometriosis. Whether formation of ectopic decidua represents a marked progestational response of endometriosis or an independent peritoneal-stromal reaction to pregnancy is unclear. This study was designed to determine the prevalence of deciduosis in the patients whose fertility were proven. Design: Prospective study of patients who had undergone cesarean delivery without history of endometriosis. Materials and Methods: The study was performed in 179 full tenn pregnant women. During the cesarean section, the pelvic organs were thoroughly investigated and the biopsies were collected at the lesions suspicious endometriosis. And then microscopic examination of removed tissues were done. Results: Of the 179 patients who underwent cesarean delivery, 48 women (26.8%) had the lesions suspicious endometriosis such as adhesion, pigmented spots. The ovary was the most frequently ocurred site (79.2%). Microscopically, decidual cells were observed in 34 cases (70.8%) of 48 biopsed patients. Conclusion: Endometriosis has been known to be associated with subfertility. Our observations found the prevalence of deciduosis was 19.0% (34/179) in tenn pregnant women whose fertilites were proven. We suggests that the deciduosis maya manifestation of endometriosis during pregnancy. However, further follow up study should be done to confirm this clinicopathologic process.

      • KCI등재

        폐경 전, 후 여성에 있어서 골밀도 예측을 위한 골대사 표지물질의 의의

        이진우,김진홍,김미란,정기욱,류순원,권동진,임용택 대한폐경학회 1999 대한폐경학회지 Vol.5 No.1

        "Recently, the biochemical markers for bone metabolism have been developed and are expected to reflect the minor change of bone turnover. Which bone tumover markers are predictive of bone mineral density (BMD) form the clinically important sites of lumbar spine and femoral neck according to the YSM remain unclear, and were the aim of this study. We compated bone formation markers: alkaline phosphatase (Alp), Osteocalcin and bone resorption markers: pyridinoline (Pyr), deoxypyridinoline (D-pyr) to see if they teflected the BMD according to the years since menopause (YSM), The subjects were divided into four groups based on their YSM. According to the groups, the mean levels of serum FSH in women 0-5YSM and 5-10YSM were significantly higher than the level in women -5-0YSM, and women 10-15YSM, also, was significantly higher than those of other groups were. And the mean level of serum E2 in women -5-OYSM was significantly higher than other groups. Pyr significantly increased compared in 0- 5, 5-10 and 10-15YSM compared with women -5-OYSM and D-pyr had an increased pattern without significance. There was no significance in Alp. and Osteocalcin according Groups. The BMD of femur neck were significantly increased in women 5-10YSM and 10-15YSM compared with women -5-OYSM and 0-5YSM. And the BMD of L2-4 and femur (Ward and Trochanter) were significantly decreased in women 0-5, 5-10 and 10-15YSM compared with women 5-OYSM. To evaluate the discrimination power of the three markers according to the groups. The Three markers and BMD were calculated according to the groups. Pyr had a strong negative correlation with BMD of L2-4 in women -5-0YSM, Osteocalcin had a negative correlation with BMD of L2-4 in women 5-10 and 10-15YSM. Pyr. in postmenopausal women significantly increased after menopause. BMD decreased later in femur neck than L2-4 and femur ward and trochanter. Marker for bone metabolism had a poup specificity, Pyr was good performance in women -5-OYSM and Osteocalcin was good performance in women 5-10 and 10-15YSM with BMD of L2-4 . "

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