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김경찬,장대식 영남이공대학 1972 論文集 Vol.1 No.-
Structural members are frequently given profiles widening toward the endes to enable the members to better resist the negative bending moment prevailing at the joints, and design calculations are usually made on the assumption that they are of uniform section, ignoring the potential effect of variation in sectional demensions. This paper considers the extent of such effect and experimentally definess the limit of the size of some such thickening of sections within which such approximate design procedures may result with sufficient engineering practicability.
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일반화 가법모형을 이용한 인천 지역 오존과 초미세먼지가 천식 악화에 미치는 영향 연구
김경찬,이혜원 한국데이터정보과학회 2022 한국데이터정보과학회지 Vol.33 No.4
We aimed to investigate the association between short-term exposure to air pollution and acute exacerbation of asthma requiring emergency departments (EDs) visit. We identified from the National Health Insurance Service environmental database of Korea 55,961 patients who visited EDs with asthma as a primary cause in Incheon during the period of 2013 and 2017. We estimated exposure to ozone (O3), particulate matter < 2.5 m (PM2.5), particulate matter <10 m (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2) and carbon monoxide (CO). We conducted a quasi Poisson regression as a time series analysis using generalized additive models to examine the association between air pollution exposure and EDs visit for asthma. We provide evidence that exposure to air pollution may increase the risk of EDs visit for asthma in Incheon. Given our findings, public health interventions to reduce levels of air pollutants including O3 and PM2.5should be conducted.
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김경찬 건국대학교 법학연구소 2011 一鑑法學 Vol.0 No.19
當前,中國存在``一國,兩制,三法系,四法域``的現象。中國大陸改革 開放政策的實施以及香港、澳門的回歸,使中國大陸與台灣地區、香港、澳門等地的交流越來越來繁起起,著不可避免地在多法域間誕生了 法律沖突、刑事管轄權沖突以及刑事司法協助等問題。首先,中國有必要相互了解各法域刑事法的特点及主要內容,倂在互相尊重和保障平等地位的基本原則下求具체的協助方案。在與刑事法相關聯上,偵査机關需要在犯罪嫌疑人的逮捕及移送、犯罪情報체體的交換、證据收集等方面進行協助的程序上的協義,刑事司法机關則可以進行犯罪被告人的起柝及移送、申判程序上的承認,以及法院判決的相互承認、犯罪所得的沒收等方面的協義。甚至煥存在通過民間机構謀求求解決問題的方式,例如在厦門和金門地設立中立區通過仲裁机構謀求相互的助的方法案是。此外,中國大陸、台灣地區、香港、澳門等地各自制定自己的區際沖突法尋求問題的解決也是一種方案。中國的特殊現壯需要一個共同目標。作爲中國特殊現壯的"一國、兩制、三法系、四法域"的現壯進管必需以相互尊重爲前提,但各地域倂不應該以各自的發展與定而存立存在。而是應該謀求能構共同發展的模式幷相互補足各地域的法律特点和優点。各地域間的交流與通通使中國形成一部統一的區際沖突法成爲可能。著首先可以種四法域的法律專家通過參照國際法的普遍原則與區域性公約共同硏究具體的問題開始入手。中國四法域法律方面的相互協助經驗必將成爲東北亞及世界各地不同法律體系間謀求共同法律基礎的實性的、基本的重要經驗.
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HL-60 세포에서 $TNF-{\alpha}$에 의한 MCP-1 발현에 미치는 Betulinic Acid의 효과
김경찬,이추희,Kim, Kyung-Chan,Lee, Chu-Hee 대한약학회 2008 약학회지 Vol.52 No.1
Betulinic acid, a naturally occurring pentacyclic triterpenoid, is found in abundance in the outer bark of white birch (Betula alba). In this study, we investigated if betulinic acid affects cytokine expression from activated macrophage cells. ELISA result showed that stimulation of HL-60 cells with proinflammatory cytokine such as $TNF-{\alpha}$ resulted in MCP-1 release into culture medium. In addition, transcriptional upregulation of MCP-1 in response to $TNF-{\alpha}$ was observed by RT-PCR analysis. However, incubation of HL-60 cells with betulinic acid prior to $TNF-{\alpha}$ treatment abrogated MCP-1 expression in transcription and translational level. Consistent with a number of studies which reported requirement of ERK activation for $TNF-{\alpha}$ expression, Western blot analysis showed that $TNF-{\alpha}-induced$ ERK activation was suppressed by pretreatment of HL-60 cells with betulinic acid. Taken together, our data indicate that betulinic acid exerts its anti-inflammatory effect through inhibition of $TNF-{\alpha}-induced$ ERK activation which is required for the subsequent MCP-1 release.
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權赫文,金炅燦 嶺南大學校 工業技術硏究所 1985 연구보고 Vol.13 No.1
Longitudinally reinforced concrete slabs are a common type of short-span highway bridge. Laid continuous over several supports, the are economically extended to medium-range spans, Aesthetic and economic considerations further suggest the slabs of uniform thickness. A 3-span prismatic slab system is one such type, where the side spans are variously proportioned relative to the central span when ceonomy primarily governs. Ratios in the range of 0.5 to 1.0 are observed, 0.7 to 0.8 being suggested as most economical. This paper runs a number of comparative designs of 3-span continuous prismatic slab systems covering the overall span lengths of 30 to 50 meters under various combinations of material grades and live loadings, and locates the economical side span ratio within a range of .76 to .84 with the most ceonomical one at .78∼.80, which corresponds to equal positive design moments in the side and central spans.
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급성심근경색증으로 발현한 이형 협심증 환자에서 5일간 지속된 가속성 심실고유 율동
김경찬,김일수,강욱,김재균,유창훈,김수홍 대한중환자의학회 2009 Acute and Critical Care Vol.24 No.1
A 56-year-old man presented with right coronary arterial spasm accompanied by ST segment elevation in the inferior leads. A reperfusion arrhythmia, accelerated idioventricular rhythm (AIVR), developed 1 hour after a nitroglycerin infusion. The AIVR was sustained for 5 days without hemodynamic instability, and resolved spontaneously during hemodynamic monitoring in the coronary intensive care unit.
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金炅燦 嶺南大學校 工業技術硏究所 1975 연구보고 Vol.3 No.1
Employing an extended number of relevant factors, a generalized formula is derived that defines the economical span lengths of given girder bridges: where C: Portion of cost per span of the superstructure regarded independent of span lengths, such as the cost of bearings and expansion joints P: Cost per site of foundation works, including a well or piles(if any) and a pier r : Unit cost of variable components of the superstructure, such as the cost (material, fabrication and handling) of concrete, steel, form and tendons c : Constants comprising a set of linear equation ) that approximate the quantities of variable components m: Number of variables The values of the factors appearing in the formula can be readily obtained: C and P from a trial design using a proposed (preliminary) span length and the current unit costs r , and a matrix of a by least-square fitting the variations of variables with regard to span lengths using the data from three or more of existing (if available) or trial designs of similar design characteristics and different span lengths. Where a design even of a multiple-span bridge of considerable length is summarily developed around a randomly chosen type and span length and "finalized" with no serious efforts made at comparative cost analyses involving the potential alternatives of different types and span lengths, the generalized formula as herein introduced (and applied to sample, modified real-life designs) will hopefully serve the designers and analysts alike.
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