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김신곤 동아대학교 학생생활연구소 2001 學生硏究 Vol.29 No.-
The purpose of this study was to developed curriculum integration according to the social changing for the information-oriented. The results of this study may be summarized as the followings. Education in this information-oriented society requires that the composition of a curriculum is directly related to learning and vice versa. That's why a curriculum integrated composition is needed. Curriculum integrated approach in curriculum development composed of four elements. That is educational objectives, selection and organization of contents, planning of instruction, and planning of evaluation. However this four elements of curriculum have relationship and interaction between them. In addition, the curricular composition by way of an integrated curriculum can help learners generate their knowledge in considering characteristics of each person and also assist learners to get whole personality.
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한국 성인에서 C-reactive Protein과 대사성 증후군의 상관성에 관한 연구
김신곤,김동림,신동현,김난희,최경묵,백세현,최동섭 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.2
Background: Metabolic syndrome (MS) is characterized by insulin resistance accompanied by one or more of the following: obesity, hypertension, impaired glucose tolerance, low HDL cholesterol levels, and/or hypertriglyceridemia. However, the precise underlying pathogenic mechanism of MS is not known. Several recent reports have suggested a positive association between components of MS and markers of the acute-phase response, including C-reactive protein (CRP). These results imply that MS is accompanied by an ongoing inflammatory process. The purpose of our study was to evaluate the association between circulating levels of C-reactive protein, a sensitive systemic marker of inflammation, with components of metabolic syndrome in Korean adults. Methods: A total of 1,461 subjects aged between 20 and 81 years, who visited the Health Management Center at Korea university between November 2000 and February 2001 were studied. We investigated the correlation between CRP levels and components of MS. The components of MS were categorized, and age-sex adjusted mean values of CRP calculated for the categorized components. The BMI was categorized into 5 classes, and the CRP levels examined according to their BMI class. In addition, subjects with a different number of the MS components were grouped as follows: group 1 for 0 components, group 2 for 1 components, group 3 for 2 components and group 4 for ≥ 3 components, and the CRP levels calculated for each group. Results: There were significant positive correlations of CRP levels with age, BMI, TG, systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBS), uric acid, insulin, and homeostasis model assessment IR (HOMAIR). A significant inverse correlation was observed between CRP levels and serum HDL. From the multivariate analysis, age and BMI were significantly correlated with CRP levels. The means of the CRP for the categorized components of MS were significantly higher in the BMI categories: ≥25 for female/27 for male, TG ≥200 ㎎/dL, fasting plasma glucose ≥126 ㎎/dL and blood pressure ≥140/90 ㎜Hg, and the CRP levels by BMI class were: 1.19 (BMI <18.5), 1.54 (BMI 18.5∼22.9), 1.59 (BMI 23.0∼24.9), 1.77 (BMI 25. 0∼29.9) and 2.07 (BMI >30.0) ㎎/L. Furthermore, the increase in the CRP levels in relation to the numbers of MS were 1.46 (group 1), 1.70 (group 2), 1.95 (group 3) and 2.11 mg/L (group 4) with statistical significance. Conclusion: The above data showed associations between the CRP levels and the different components of MS. This might suggest that MS in Koreans could be accompanied by a systemic inflammation response
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김신곤,김형록,문석진,정상용 대한혈관외과학회 1991 Vascular Specialist International Vol.7 No.1
The management of compartment hypertension appears to be a valuable adjunctive procedure to improve the limb survival in various situations. In acute arterial occlusive diseases or arterial injuries when initial treatments are delayed, fasciotomy is indicated in addition to restoration of the blood flow. The authors evaluated clinically nine cases of the fasciotomy which were performed after arterial surgery for five years since 1985. The most common underlying disease was atherosclerosis and delay in diagnosis and treatment of acute arterial occlusion was the commonest indication. Limb amputaion was done in two cases and mortality in three cases. Delay in management less than 24 hours had a high limb salvage rate. High index of suspicion and early diagnosis and appropriate fasciotomy may increase limb salvage in acute arterial ischemic diseases.
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김신곤,김형록,정상영 대한혈관외과학회 1991 Vascular Specialist International Vol.7 No.1
There are several problems in the treatment of congenital arteriovenous malformation in the neck. Variable anatomical position, multiplicity of the lesion and indefinite margin with deep structures limit radical excision. A 24 years old male who complainted thumb-tip sized throbbing mass on the left biopsy at local clinic. The cervical mass, above mentioned, was defined to congenital arteriovenous malformation which was supplied by facial and lingual arteries, left rather than right side, in carotid arteriography. He was treated by transcatherteric arterial embolization in three times and showed transient improvement but the lesion was recurred 6 month later. Ligation of left facial, ligual artery which were suspected as main feeding arteries was performed. Immediate postoperatively, the size of mass was decreased and pulsation was disappeared but transient deviation of tongue was appeared then subsided slowly. He was discharged with good condition. Two months later, follow-up carotid arteriography showed new feeding artery, left internal maxillary artery, was developed and hypertrophy of right facial and lingual arteries which supplied minimal amount of blood to lesion preoperatively was noted.
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전격성 진행을 보인 Listeria Monocytogenes 패혈증-뇌막염 1예
박승철,김우주,김민자,정희진,김신곤 대한감염학회 1995 감염 Vol.27 No.6
Listeria monocytogenes is the only human pathogen among seven species in this genus and listeriosis generally occurs in of pregnacy or immunosuppression due to illness or medication. Sepsis and meningitis are the most common presentations of listeriosis in non-pregnant adults. However, meningitis and sepsis due to L. monocytogenes is not clinically distinguishable from those due to other bacteria. We have experienced a fatal case of listeriosis presenting as fulminant sepsis-meningitis. Initially, the case was mistaken as a fulminant meningococcemia with meningitis because the case showed fulminant clinical course and scattered purpuric lesions on whole body. Later, this case was confirmed as L. monocytogenes sepsis-meningitis.
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