정신보건전달체계내 알코올 및 약물중독 영역의 위상

오동열(Dong Yul Oh) 대한사회정신의학회 2001 사회정신의학 Vol.6 No.1

국내 알코올, 약물, 마약중독관련 현황을 살펴보면, 현재까지는 입원위주의 치료가 주로 이루어졌으며, 단기입원이나 직업재활은 많지 않았다. 단지 정신보건법상에 보건소업무로 알코올 및 약물중독자관리가 들어감으로써 향후 지역사회 관리, 재활이 활성화될 전망이나 국내실정에 맞는 전달체계가 없는 상태이다. 알코올에 비해 마약은 국민의 건강에 미치는 건강의 심각성이 커서 강력한 엄벌주의를 채택하여 공급의 차단에는 성공하고 있으나 향후 수요의 차단을 위주로 한 치료, 재활이 강화되어야 한다. 알코올이나 약물중독이나 중독자를 지역사회에서 꾸준히 발견하여 입원치료를 시키고 이들이 재활할 수 있는 방안을 꾸준히 찾아 나아가야 한다. 이들은 항상 재발을 빈번하게 하므로 의료적인 모델하에서 꾸준히 치료해주는 것이 중요하다. We investigated the care system of alcoholism and drug addiction, and we find that the treatment system is mainly for admission and a few of short-term admission and job-training. we have no delivery system in addiction field except the role of health center, which is to control alcohol and drug addiction problem. Comparing to alcohol problem, Drug addiction problem can be a serious impact to public health and we can have success of contol in some aspect but we have no good treatment and rehabilitation system on the contrary. So we should develop the way to find out the addiction patient and to treat and train them. Also we should make the continuing after-care system, because alcohol and drug addiction have the special characteristics to recur frequently.

항정신병약물성 악성증후군

오동열,Davis,John M. 大韓神經精神醫學會 1993 신경정신의학 Vol.32 No.4

The recent increase in the reporting of NMS in the psychiatric and medical literature is most likely due to our increasing awareness of the syndrome. The neuroleptic malignant syndrome is an acute disorder of thermoregulation and neuromotor control, and it appears that decreased dopaminergic tone in the striatum and in the hypothalamus may underlie the development of EPS and altered thermorgulation in NMS. Identifying biological markers and exploring potential pathophysiological mechanisms will be important. Such research could be leaded by clues regarding the pathogenesis of similar disorder such as malignant hyperthermia, lethal catatonia. This type of research would be significantly enhanced by the development of appropriate animal models. There is a ongoing debate about whether NMS is a spectrum diorger and there have been numerous observations of atypical cases that may lack one of the key features or present with only mild to moderate evidence of one or more features. There is a great need to for a more sophisticated epidemiological approach on the basis of case reports. The subject of NMS had continued to cause considerable interest, particularly in Korea where there is still no study articles about its incidence or treatment. Recently it is reported that at the relatively low dose of neuroleptis, a large percentage of patients showed adequate response, theoretically minimize the risk of NMS. It is needed to be more attentive to a growing body of literature indicating that "less may indeed be more" when it comes to the dose of neuroleptic. Case reports and controlled prospective studies will be necessary to accomplish this. Clearly, there is much we do not understand about this potentially fatal disorder. Future research could importantly serve our efforts in prevention and therapy and greatly enhance our understanding of basic pathophsiological mechanisms.

흰쥐 C6 신경교종 세포에서 Venlafaxine 그리고 Dexamethasone 처리가 열충격 단백질 70의 발현에 미치는 영향

유재학,이준석,양병환,최미란,채영규,김석현,노성원,오동열,최인근,Yu, Jae-Hak,Lee, Jun-Seok,Yang, Byung-Hwan,Choi, Mi-Ran,Chai, Young-Gyu,Kim, Seok-Hyeon,Roh, Sung-Won,Oh, Dong-Yul,Choi, Ihn-Geun 대한생물정신의학회 2005 생물정신의학 Vol.12 No.2

Object:The intracellular action of the antidepressant, venlafaxine, was studied in C6-gliomas using heat shock protein 70(HSP70) immunocytochemistry and HSP70 Western blots because HSP70 is associated with stress and depression. Methods:To examine how the glucocorticoid affects the expression of HSP70 in nerve cells, the rat C6 glioma cell was treated with dexamethasone for 6 hours. In addition, venlafaxine was administered to the experimental groups of C6 glioma cells for 1, 6, 24, and 72 hours each, after which the expression of HSP70 was investigated. Finally, venlafaxine and dexamethasone were simultaneously administered to the experimental groups for 1, 6, 24, and 72 hours, followed by an investigation of the expression of HSP70. Results:The short term(1 hour) venlafaxine treatment significantly increased the level of HSP70 expression. The short term treatment of venlafaxine with dexamethasone also increased the level of HSP70 expression but this reduction was not statistically significant. The long term(72 hours) venlafaxine with dexamethasone treatment significantly reduced the level of HSP70 expression. The long term treatment of venlafaxine also reduced the level of HSP70 expression but this reduction was not statistically significant. Dexamethasone(10uM, 6hours) did not affect the level of HSP70 expression compared with controls. Conclusion:Venlafaxine increases the expression of HSP70 at short term treatment, but prolonged treatment with dexamethasone suppresses the expression of HSP70.

體表面積 및 年齡이 換氣機能에 미치는 影響에 대하여

吳東烈 대한의학협회 1965 대한의학협회지 Vol.8 No.8

Tape Automated Bonding 기술

오동열 대한전자공학회 1991 전자공학회지 Vol.18 No.4

가정가족 병리와 정신장애에 관한 임상적 연구

오동열,서성원 국립서울정신병원 1987 臨床硏究論文集 Vol.1987 No.-

스캐닝 과정에서 발생하는 전자문서의 기하학적 변형감지에 관한 연구

오동열(Oh, Dong-Yeol),오해석(Oh, Hae-Seok),류성열(Rhew, Sung-Yul) 한국산학기술학회 2009 한국산학기술학회논문지 Vol.10 No.8

기존 종이 문서를 영상 파일로 변환하기 위해서 스캐너와 같은 광학기를 사용하게 된다. 스캐닝 과정에서 문서가 제대로 문서 영상으로 생성되었는지를 판단하기 위해서 이미지 품질 검사 과정을 거치게 된다. 이미지 품질 검사 과정에서는 스캐너 기기의 특성상 스캐닝 과정에서 발생할 수 있는 문서 영상의 기울기, 노이즈 여부, 문서가 접힌 상태로 스캔되었는지의 여부 등을 체크하게 된다. 이에 본 논문에서는 스캐너를 이용하여 문서 영상을 생성 과 정에서 발생하는 기하학적 변형을 평가하기 위한 방법론을 제시한다. 본 연구에서는 품질 검사의 검사 항목에 대해서 영상 처리를 이용하여 각각의 변형 정도를 측정하고 각각의 변형 정도가 실제 문서의 가독성에 얼마나 영향을 미치 는지를 OCR 결과 값과 비교한다. OCR 인식 성공 비율과 각 항목별 변형 정도를 나타내는 측정 값 간에 상관관계를 분석하기 위해서 피어슨 상관 계수(Pearson Correlation Coefficient)를 이용하고 이를 기반으로 실제 문서 영상의 변형 정도를 평가하기 위한 가중치 값을 산정한다. 제시한 방법으로 평가에서 높은 평가 값으로 계산된 영상 문서는 OCR 인식률에서도 높은 인식 결과를 나타내고 있다. Scanner which is a kind of optical devices is used to convert paper documents into document image files. The assessment of scanned document image is performed to check if there are any modification on document image files in scanning process. In assessment of scanned documents, user checks the degree of skew, noise, folded state and etc This paper proposed to how to measure geometrical modifications of document image in scanning process. In this study, we check the degree of modification in document image file by image processing and we compare the evaluation value which means the degree of modification in each items with OCR success ratio in a document image file. To analyse the correlation between OCR success ratio and the evaluation value which means the degree of modification in each items, we apply Pearson Correlation Coefficient and calculate weight value for each items to score total evaluation value of image modification degrees on a image file. The document image which has high rating score by proposed method also has high OCR success ratio.

약물성 파킨슨 증후군, 지연성운동장애 및 정좌불능의 공존

오동열,이원익,김창현 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.6

The authors studied about the prevalence of drug-induced parkinisonism(DIP), tardive dyskinesia(TD) and akathisia(AK) and also coexistence of them in 442 psychiatric inpatients at Seoul National Mental Hospital. We examined also several variables including age, sex, dosage of drug, duration of exposure to drug, duration of illness, whether they can be a risk factors to each of the side effect, DIP, TD and AK. The results of study were as follows : 1) The prevalence of abnormal movement disorder in 442 psychiatric inpatients was 43.7% and the prevalence of TD, DIP, AK, TD with DIP, EIP with AK, TD with AK and TD with DIP and AK was 14.2%, 7.5%, 2.4%, 3.9% and 0.6% respectively. 2) The prevalence of TD in the body was 40.4% in tongue, 18.2% in lower extremity, 15.7% in upper extremity, 9.6% in jaw, 7.6% in trunk, 4.5% in lip, 4.0% in face respectively. In DIP, the prevalence of each subscale was 30.3% in akathisia, 19.5% in salivation and 1.3% in walking difficulty. 3) The three variables, like age, duration of drug administration, duration of illness, can be risk factors to TD and TD with DIP group, but another four variables, sex, dose of antipsychotics, past ECT history and duration of total admission, were not. Conclusively, DIP, TD and AK coexisted in high rates, so we should be cautious about the treatment of coexisting case. Tardive dyskinesia and drug-induced parkinsonism have been hypothesized to reflect opposing states of dopamine function in striatum. In fact, long-term prospective study should be done to evaluate the correlation of dopamine activity and each side effect like TD, DIP and AK.

노년기 인격 장애자에 대한 임상적 연구

오동열,정은기 국립서울정신병원 1987 臨床硏究論文集 Vol.1987 No.-

허밍 질의 기반 음악 검색 시스템의 유사도 계산 알고리즘

오동열(Oh Dong Yeol),오해석(Oh Hae Seok) 한국컴퓨터정보학회 2006 韓國컴퓨터情報學會論文誌 Vol.11 No.4

사람은 음악에서의 선율을 악보의 기보법과 같이 음표의 높이와 음표의 길이가 조합된 형태로서 기억하는 것이 아니라, 전반적인 음표 간의 높낮이의 흐름과 음표 사이의 상대적인 지속시간으로 구성된 음조 곡선 형태로 기억한다. 이와같은 선율의 기억 방식으로 인해 기존 음악 검색 시스템과 같이 건반을 이용한 주선율 입력이나 악보에 기보된 형태로 음악 검색의 질의를 이용하는 방법을 그대로 적용하기 어려운 점이 있다. 이에 본 논문에서는 사용자의 허밍을 질의로 사용하는 음악 검색 시스템에서의 고려 대상들과 기존에 연구된 허밍 질의 기반의 음악 검색 시스템을 살펴본다. 또한 사람이 선율을 기억하는 방식인 상대적인 음표 간 높낮이와 음표 지속 시간을 이용하여 음악 내에 특징 정보를 추출하고 이를 기반으로 허밍 질의와 단음과의 유사도 계산 알고리즘을 제안한다. 제안된 유사도 계산 알고리즘은 선율내의 음높이 차만 가지고 선율의 유사도를 비교하는 경우 발생할 수 있는 문제를 연속된 음간에 길이 차이를 이용하여 해결하였다. A user remembers a melody as not the combination of pitch and duration which is written in score but the contour which is composed of the relative pitch and duration. Because of the way of remembering a melody, the previous Music Information Retrieval Systems which uses keyboard playing or score as the main input melody are not easily acceptable in Query By Humming Systems. In this paper, we mention about the considerable checkpoints for Query By Humming System and previous researches. And we propose the feature extraction which is similar with the way of remembering a melody and similarity computation algorithms between melody in humming and melody in music. The proposed similarity computation algorithms solves the problem which can be happened when only uses the relative pitches by using relative durations.