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莫先武 한중인문학회 2005 한중인문학연구 Vol.15 No.-
왕국유는 중국 역사상 현대 미학을 체계적으로 연구한 첫 번째로 인물이다. 그의 境界涚은 중국의 전통적인 이론인 意境涚을 현대 미학의 범주로 이끌어 주었다. 그는 철저하게 중국 전통의 功利主义 미학관을 배격하고 이를 天功利主义 미학관으로 대체하였다. 또한 이러한 기초위에 詩學의 가치를 인생의 가치와 결합시키게 해주어 시학의 인문 가치를 높여 주었다. 무공리주의 미학관과 현대 미학 이론의 기초위에 왕국유는 독창적인 경계 미학을 창조해 내었으니, 이는 중국 미학사에서 미증유의 일이었다. 왕국유의 境界 미학은 중국 전통의 의경론과 서방 현대 미학에 대한 새로운 해석이니, 이는 중국 當代 문학 이론의 중요한 방법론이 되어 주었다. As the first person studying esthetics, WANG Guowei turned the traditional Artistic Conception into modern esthetics. He thoroughly abandoned the traditional utility esthetics and established modern no-utility esthetics. Based on no-utility esthetics, he opened poem-humanity value in china by contacting literature with humanity, created modern systematical Artistic-Conception-esthetics, based on his modern experience of human nature, he re-readed Chinese traditional Artistic Conception and modern esthetics of west.
제11회 한,중 형법 국제 학술심포지엄 : 중국 기업범죄의 현황과 원인 및 대책
모홍씨엔 ( Hong Xian Mo ) 한국비교형사법학회 2013 비교형사법연구 Vol.15 No.2
Most of the corporate crimes occurring in our country belong to a part of the intersection of unit crime and economic crime, and the amount which is not reflected on statistical data is huge. Our country applies the principle of “double punishment is the rule, single punishment is an exception” to corporate crime, and monetary fine is the only penalty for corporate. The main reasons for corporate crime include kinds of systems and mechanisms which are represented by modern corporation system and market economic system being inefficient, relevant laws lagging behind and so on. Therefore, to prevent corporate crime, we should focus on improving the institutional mechanisms, relevant laws and regulations.
Challenges and Advances in Materials and Fabrication Technologies of Small-Diameter Vascular Grafts
Mei‑Xian Li,Qian‑Qi Wei,Hui‑Lin Mo,Yu Ren,Wei Zhang,Huan‑Jun Lu,정윤기 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
The arterial occlusive disease is one of the leading causes of cardiovascular diseases, often requiring revascularization. Lack of suitable small-diameter vascular grafts (SDVGs), infection, thrombosis, and intimal hyperplasia associated with synthetic vascular grafts lead to a low success rate of SDVGs (< 6 mm) transplantation in the clinical treatment of cardiovascular diseases. The development of fabrication technology along with vascular tissue engineering and regenerative medicine technology allows biological tissue-engineered vascular grafts to become living grafts, which can integrate, remodel, and repair the host vessels as well as respond to the surrounding mechanical and biochemical stimuli. Hence, they potentially alleviate the shortage of existing vascular grafts. This paper evaluates the current advanced fabrication technologies for SDVGs, including electrospinning, molding, 3D printing, decellularization, and so on. Various characteristics of synthetic polymers and surface modification methods are also introduced. In addition, it also provides interdisciplinary insights into the future of small-diameter prostheses and discusses vital factors and perspectives for developing such prostheses in clinical applications. We propose that the performance of SDVGs can be improved by integrating various technologies in the near future.
Qiang Xia,Mo Xu,Han Zhang,Qiang Zhang,Xian-xuan Xiao 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.1
Most of the analytical and numerical models of tunnel groundwater inflow ignore the excavation process, leading to inaccurate prediction of discharge rate. A dynamic modeling approach was introduced by redevelopment of MODFLOW to simulate the change of groundwater flow step by step in accord with tunnel excavation. The drilling tunnel was conceptualized as a changing boundary condition, which was modeled by dividing the drilling process into a series of successive steps. The impact of permeability heterogeneity on groundwater flow was studied through a comparison between a homogeneous hydraulic conductivity case and a synthetic heterogeneous one. It was found that the discharge rate at drilling front kept stable in the homogeneous case, resulting in a linear increase in the total discharge rate, similar to the analytical solution by Perrochet (2005). In contrast, the front and total discharge rate were influenced significantly by the variability of permeability in the heterogeneous case. The time-dependent discharge rate at a given place was subject to an exponential decay for both cases with the maximum inflow occuring at the beginning of excavation. The relationship between discharge rate and hydraulic properties was further investigated in a high-K zone. It revealed that maximum discharge rate was proportional to hydraulic conductivity (K) and specific storage (Ss). The decaying rate of discharge was time-dependent and also proportional to the value of K and Ss. The water budget analysis demonstrated that water released from storage of the high-K zone was the major source of tunnel discharge at early times.
Zhi-Zhun Mo,Zhi-Xiu Lin,ZiRen Su,Lin Zheng,Hui-Lin Li,JianHui Xie,Yan-Fang Xian,Tie-Gang Yi,Shui-Qing Huang,Jian-Ping Chen 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.9
Angelica sinensis (AS, Danggui in Chinese) is an important herbal component of various traditional formulae for the management of asthenia and its tonic effects. Although AS has been shown to ameliorate cognitive damage and nerve toxicity in D-galactose (D-gal)-elicited senescent mice brain, its effects on liver and kidney injury have not yet been explored. In this work, mice were subjected to hypodermic injection with D-gal (200 mg/kg) and orally gavaged with AS (20, 40, or 80 mg/kg) once a day for 8 successive weeks. Results revealed that AS significantly improved liver and kidney function as assessed by organ index and functional parameters. In addition, AS pretreatment effectively ameliorated the histological deterioration. AS attenuated the MDA level and markedly enhanced the activities and gene expressions of antioxidative enzymes, namely Cu, Zn-SOD, CAT, and GPx. Furthermore, AS markedly inhibited the D-gal-mediated increment of expressions of inflammatory cytokines iNOS, COX-2, IκBα, p-IκBα, and p65 and promoted the IκBα expression level in both hepatic and renal tissues. In sum, AS pretreatment could effectively guard the liver and kidney of mice from D-gal-induced injury, and the underlying mechanism was deemed to be intimately related to attenuating oxidative response and inflammatory stress.
Biosynthetic Pathway for Poly(3-Hydroxypropionate) in Recombinant Escherichia coli
Qi Wang,Changshui Liu,Mo Xian,Yongguang Zhang,Guang Zhao 한국미생물학회 2012 The journal of microbiology Vol.50 No.4
Poly(3-hydroxypropionate) (P3HP) is a biodegradable and biocompatible thermoplastic. In this study, we engineered a P3HP biosynthetic pathway in recombinant Escherichia coli. The genes for malonyl-CoA reductase (mcr, from Chloroflexus aurantiacus), propionyl-CoA synthetase (prpE, from E. coli), and polyhydroxyalkanoate synthase (phaC1, from Ralstonia eutropha) were cloned and expressed in E. coli. The E. coli genes accABCD encoding acetyl-CoA carboxylase were used to channel the carbon into the P3HP pathway. Using glucose as a sole carbon source, the cell yield and P3HP content were 1.32 g/L and 0.98% (wt/wt [cell dry weight]), respectively. Although the yield is relatively low,our study shows the feasibility of engineering a P3HP biosynthetic pathway using a structurally unrelated carbon source in bacteria.
Zhi-Hai Ni,Xian-Jun Liang,Jing-Gang Mo,Yi Zhang,Jian-Hua Liang,Yu-Sha Yang,Yong Zhou,Zhao-Hua Li,Jian-Liang Zhang,Yin-Lu Ding,Peng Zhang,Jin-Qing Wang 한국유전학회 2015 Genes & Genomics Vol.37 No.11
We aim to investigate the correlations of hypoxia inducible factor-1a (HIF-1a) C1772T (rs11549465) and G1790A (rs11549467) gene polymorphisms with digestive tract cancers. A sum of 267 digestive tract cancers patients were hospitalized in Taizhou Central Hospital of Zhejiang Province as case group between December 2012 and December 2014. Additionally, 275 healthy people who had a physical examination in our hospital at the same time were selected as control group. Polymerase chain reaction-restriction fragment length polymorphism was utilized for detecting allele and genotype frequency of different locus in case and control group. Meta-analysis was performed using Comprehensive Metaanalysis 2.0 (Biostat Inc., Englewood, New Jersey, USA). Our result showed statistical significance only exists in family history of cancer between case and control group (P\0.05). Both C1772T (rs11549465) and G1790A (rs11549467) polymorphisms showed positive correlations with an increasing risk of digestive tract cancers. The frequencies of TT genotype of C1772T (rs11549465) and GA, AA genotypes of G1790A (rs11549467) polymorphisms in case group were evidently higher compared with the controls (all P\0.05). Besides, the comparison of allele and dominant models of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) between two groups showed a significant difference (all P\0.05). Meta-analysis results further confirmed that the onset risk of digestive tract cancers may be improved under allele and dominant models of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) (all P\0.05). Single nucleotide polymorphisms of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) may play a role in development of digestive tract cancers.