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      • KCI등재

        Preparation and characterization of Mn doped copper nitride films with high photocurrent response

        Aiai Yu,Ruiyuan Hu,Wei Liu,Rui Zhang,Jian Zhang,Yong Pu,Liang Chu,Jianping Yang,Xingao Li 한국물리학회 2018 Current Applied Physics Vol.18 No.11

        The Mn-doped copper nitride (Cu3N) films with Mn concentration of 2.0 at. % have high crystallinity and uniform surface morphology. We found that the as-synthesized Mn-doped Cu3N films show suitable optical absorption in the visible region and the band gap is ∼1.48 eV. A simple photodetector based on Mn doped Cu3N films was firstly fabricated via magnetron sputtering method. The fabricated device with doping of Mn demonstrated high photocurrent response and fast response shorter than 0.1 s both for rise and decay time superior to the pure Cu3N. Furthermore, the energy levels of Mn-doped Cu3N matched well with ITO and Ag electrode. The excellent photoelectric properties reflect a good balance between sensitivities and response rate. Our investigation reveals the excellent potential of Mn-doped Cu3N films for application of photodetectors.

      • KCI등재

        Drainage procedure for pancreatolithiasis: re-examination of the pancreatic duct diameter standard

        Guoyong Chen,Yu You,Hongxian Yan,Junchuang He,Jianping Gong,Sidong Wei 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.98 No.4

        Purpose: Pancreatic duct decompression relieves pancreatic duct stone (PDS)-associated abdominal pain, though a consensus indication for the drainage procedure of the main pancreatic duct (MPD) is lacking. Moreover, major prognostic factors for postsurgical long-term pain relief and recurrence are largely unknown. Methods: The clinical outcomes of 65 consecutive PDS patients undergoing surgery from 2008–2012 with 3+ years of follow-up were assessed. Results: At postsurgical follow-up (median, 4.5 years; range, 3–7 years; procedure: Partington, n = 32; Frey, n = 27; pancreatoduodenectomy, n = 3; distal pancreatectomy, n = 3), the early complication and complete stone clearance rates were 29.2% and 97%, respectively. Long-term, complete and partial pain relief were 93.9%, 83.1%, and 10.8%, respectively. The risk of pancreatic fistula was higher in the <8 mm group than in the >8 mm group (P < 0.05), and 80% of the pancreatic fistula cases occurred in the <8 mm group. A shorter pain duration (P = 0.007), smaller MPD diameter (P = 0.04), and lower Izbicki pain score (P < 0.001) predicted long-term pain relief. Pain recurrence after initial remission occurred in 5 patients and was only related to pain duration (P = 0.02). Stone recurrence and pancreatic exocrine functional and endocrine functional deterioration occurred in 2, 5, and 11 patients, respectively. Conclusion: Surgery provides excellent stone clearance, long-term pain relief, and acceptable postoperative morbidity. Using 8 mm as the criterion for drainage surgery can minimize the postoperative pancreatic fistula risk. Individualized and timely surgical treatment may improve the effect of surgery.

      • KCI등재

        Efficient Signature Schemes from R-LWE

        ( Ting Wang ),( Jianping Yu ),( Peng Zhang ),( Yong Zhang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.8

        Compared to the classical cryptography, lattice-based cryptography is more secure, flexible and simple, and it is believed to be secure against quantum computers. In this paper, an efficient signature scheme is proposed from the ring learning with errors (R-LWE), which avoids sampling from discrete Gaussians and has the characteristics of the much simpler description etc. Then, the scheme is implemented in C/C++ and makes a comparison with the RSA signature scheme in detail. Additionally, a linearly homomorphic signature scheme without trapdoor is proposed from the R-LWE assumption. The security of the above two schemes are reducible to the worst-case hardness of shortest vectors on ideal lattices. The security analyses indicate the proposed schemes are unforgeable under chosen message attack model, and the efficiency analyses also show that the above schemes are much more efficient than other correlative signature schemes.

      • KCI등재

        Intra-articular Injection of Chitosan-Based Supramolecular Hydrogel for Osteoarthritis Treatment

        Mou Donggang,Yu Qunying,Zhang Jimei,Zhou Jianping,Li Xinmin,Zhuang Weiyi,Yang Xuming 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.1

        Background: Pain and cartilage destruction caused by osteoarthritis (OA) is a major challenge in clinical treatment. Traditional intra-articular injection of hyaluronic acid (HA) can relieve the disease, but limited by the difficulty of long-term maintenance of efficacy. Methods: In this study, an injectable and self-healing hydrogel was synthesized by in situ crosslinking of N-carboxyethyl chitosan (N-chitosan), adipic acid dihydrazide (ADH), and hyaluronic acid–aldehyde (HA-ALD). Results: This supramolecular hydrogel sustains good biocompatibility for chondrocytes. Intra-articular injection of this novel hydrogel can significantly alleviate the local inflammation microenvironment in knee joints, through inhibiting the inflammatory cytokines (such as TNF-α, IL-1β, IL-6 and IL-17) in the synovial fluid and cartilage at 2- and even 12-weeks post-injection. Histological and behavioral test indicated that hydrogel injection protected cartilage destruction and relieved pain in OA rats, in comparison to HA injection. Conclusion: This kind of novel hydrogel, which is superior to the traditional HA injection, reveals a great potential for the treatment of OA. Background: Pain and cartilage destruction caused by osteoarthritis (OA) is a major challenge in clinical treatment. Traditional intra-articular injection of hyaluronic acid (HA) can relieve the disease, but limited by the difficulty of long-term maintenance of efficacy. Methods: In this study, an injectable and self-healing hydrogel was synthesized by in situ crosslinking of N-carboxyethyl chitosan (N-chitosan), adipic acid dihydrazide (ADH), and hyaluronic acid–aldehyde (HA-ALD). Results: This supramolecular hydrogel sustains good biocompatibility for chondrocytes. Intra-articular injection of this novel hydrogel can significantly alleviate the local inflammation microenvironment in knee joints, through inhibiting the inflammatory cytokines (such as TNF-α, IL-1β, IL-6 and IL-17) in the synovial fluid and cartilage at 2- and even 12-weeks post-injection. Histological and behavioral test indicated that hydrogel injection protected cartilage destruction and relieved pain in OA rats, in comparison to HA injection. Conclusion: This kind of novel hydrogel, which is superior to the traditional HA injection, reveals a great potential for the treatment of OA.

      • Modified Pulse Train Control Technique for Switching DC-DC Converters

        Jinping Wang,Jianping Xu,Yu Gao,Yanni Lan 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5

        Modified pulse train (MPT) control technique for switching dc-dc converter operating in continuous conduction mode (CCM) is proposed and studied in this paper. By using MPT control technique, much faster transient response than that of pulse train (PT) controlled switching dcdc converter can be obtained, which is verified by experimental results.

      • KCI등재

        Anti-hyperuricemic and nephroprotective effects of Rhizoma Dioscoreae septemlobae extracts and its main component dioscin via regulation of mOAT1, mURAT1 and mOCT2 in hypertensive mice

        Junxia Su,Yu-Hui Wei,Minglong Liu,Tianxi Liu,Jianhua Li,Yuanchun Ji,Jianping Liang 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.10

        Rhizoma Dioscoreae septemlobae (RDSE) hasbeen widely used for the treatment of hyperuricemia inChina. However, the therapeutic mechanism has beenunknown. This study investigated the antihyperuricemicmechanisms of the extracts obtained from RDSE and itsmain component dioscin (DIS) in hyperuricemic mice. Hyperuricemic mice were induced by potassium oxonate(250 mg/kg). RDSE or DIS was orally administered tohyperuricemic mice at dosages of 319.22, 638.43,1276.86 mg/kg/day for 10 days, respectively. Uric acid orcreatinine in serum and urine was determined by HPLC orHPLC–MS/MS, respectively. The xanthine oxidase (XO)activities in mice liver were examined in vitro. Proteinlevels of organic anion transporter 1 (mOAT1), uratetransporter 1 (mURAT1) and organic cation transporter 2(mOCT2) in the kidney were analyzed by western blotting. The results indicated that uric acid and creatinine in serumwere significantly increased by potassium oxonate, ascompared to that of control mice. Compared saline-treatedgroup, after RDSE treatment in the high and middle dose,the expression of mOAT1 increased 47.98 and 54.48 %,respectively, which accompanied with the decreasedexpression of mURAT1 (47.63 %) in high dose. After DIS treatment in high, middle and low dose, the expression ofmOAT1 increased 23.93, 32.80 and 25.28 % compared tosaline-treated group, respectively, which accompanied withthe decreased expression of mURAT1 (51.07, 51.42 and51.35 %). However, RDSE and DIS displayed a weak XOinhibition activity compared with allopurinol. Therefore,RDSE and DIS processed uricosuric and nephroprotectiveactions by regulation of mOAT1, mURAT1 and mOCT2.

      • KCI등재

        Young Schema Questionnaire: Factor Structure and Specificity in Relation to Anxiety in Chinese Adolescents

        Yulei Yan,Jianping Wang,Wei Yu,Li He,Tian P.S. Oei 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.1

        ObjectiveaaThe goal of this study was to examine the factor structure of Young Schema Questionnaire-short form (YSQ-SF) in a sample of Chinese adolescents, and to explore which maladaptive schemas were associated with anxiety symptoms. MethodsaaYSQ-SF was administered to 983 nonclinical Chinese adolescents aged 13–17 years. Confirmatory factor analyses with weighted least squares means and variance adjusted estimation were conducted to examine the factor structure of YSQ-SF. Stepwise regression analyses were performed to identify schemas associated with anxiety symptoms. ResultsaaA bifactor model with 15 correlated factors fitted the data better than other priori defined models. Stepwise regressions showed Vulnerability to harm, Abandonment, Emotional inhibition, Subjugation, and Unrelenting standards schemas were associated with anxiety symptoms. Furthermore, different anxiety symptoms were associated with common and distinctive schemas. ConclusionaaMaladaptive schemas were already stably formed in Chinese adolescents, however there’s no robust evidence for the existence of domain. The explanatory value of maladaptive schemas for understanding psychopathology of anxiety in adolescence is discussed.

      • KCI등재

        Derivation and isomorphism identification of valid topological graphs for 1-, 2-DOF planar closed mechanisms by characteristic strings

        Yi Lu,Bingyi Mao,Jianping Yu 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.1

        A characteristic string approach is presented for derivation and isomorphism identification of valid topological graphs (TGs) for some 1, 2-DOF (degree of freedom) planar closed mechanisms from the contracted graphs (CGs). First, topological graph (TG) is simplified by the topology graph with digits (DTG) for the 1-, 2-DOF planar closed mechanisms. Second, the equivalent conditions between the characteristic string and DTG are determined and verified by some created simulation mechanisms of valid TGs, a complicated derivation of TG is transformed into an easy derivation of the characteristic string. Third, the valid characteristic strings are derived corresponding to non-isomorphic TGs, and the invalid characteristic strings corresponding to the isomorphic and invalid TGs are determined using the characteristic string. Finally, many valid characteristic strings for the 2-DOF planar mechanisms are derived from some valid characteristic strings for the 1-DOF planar mechanisms.

      • KCI등재

        Flexural behaviour of reinforced concrete beams strengthened with NSM CFRP prestressed prisms

        Jiong-Feng Liang,Deng Yu,Shengjun Xie,Jianping Li 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.62 No.3

        The behaviour of reinforced concrete beams strengthened with near surface mounted (NSM) CFRP prestressed prisms was experimentally investigated. Five RC beams were tested under four point bending. All beams were made with dimensions of 300 mm in width, 2000 mm in length and 150 in depth. The effects of presstress level of CFRP prestressed prisms and prism material type were studied. The failure mode, load capacity, deflection, CFRP strain, steel strain and ductility of the tested beams were all analyzed. The results showed that the behavior of the reinforced concrete beams strengthened with NSM CFRP prestressed prisms showed a significant increase in the load-carrying capacity and the deformation capacity. The NSM CFRP prestressed prisms strengthening technique could be considered as an effective method for repairing RC structures.

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