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Bilingual Multiword Expression Alignment by Constituent-Based Similarity Score
( Hyeong-won Seo ),( Hongseok Kwon ),( Min-ah Cheon ),( Jae-hoon Kim ) 한국정보처리학회 2016 Journal of information processing systems Vol.12 No.3
This paper presents the constituent-based approach for aligning bilingual multiword expressions, such as noun phrases, by considering the relationship not only between source expressions and their target translation equivalents but also between the expressions and constituents of the target equivalents. We only considered the compositional preferences of multiword expressions and not their idiomatic usages because our multiword identification method focuses on their collocational or compositional preferences. In our experimental results, the constituent-based approach showed much better performances than the general method for extracting bilingual multiword expressions. For our future work, we will examine the scoring method of the constituent-based approach in regards to having the best performance. Moreover, we will extend target entries in the evaluation dictionaries by considering their synonyms.
Seo, Juhee,Kim, Dong Ho,Lim, Jung Sub,Koh, Jae-Soo,Yoo, Ji Young,Kong, Chang-Bae,Song, Won Seok,Cho, Wan Hyeong,Jeon, Dae-Geun,Lee, Soo-Yong,Lee, Jun Ah The Korean Pediatric Society 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.9
Purpose: We performed a pilot study to determine the benefit of high-dose chemotherapy and autologous peripheral blood stem cell transplantation (HDCT/autoPBSCT) for patients with Ewing sarcoma family of tumors. Methods: We retrospectively analyzed the data of patients who received HDCT/autoPBSCT at Korea Cancer Center Hospital. Patients with relapsed, metastatic, or centrally located tumors were eligible for the study. Results: A total of 9 patients (3 male, 6 female), with a median age at HDCT/autoPBSCT of 13.4 years (range, 7.1 to 28.2 years), were included in this study. Patients underwent conventional chemotherapy and local control either by surgery or radiation therapy, and had achieved complete response (CR, n=7), partial response (n=1), or stable disease (n=1) prior to HDCT/autoPBSCT. There was no transplant-related mortality. However, the median duration of overall survival and event-free survival after HDCT/autoPBSCT were 13.3 months (range, 5.3 to 44.5 months) and 6.2 months (range, 2.1 to 44.5 months), respectively. At present, 4 patients are alive and 5 patients who experienced adverse events (2 metastasis, 2 local recur, and 1 progressive disease) survived for a median time of 2.8 months (range, 0.1 to 10.7 months). The 2-year survival after HDCT/autoPBSCT was $44.4%{\pm}16.6%$ and disease status at the time of HDCT/autoPBSCT tended to influence survival ($57.1%{\pm}18.7%$ of cases with CR vs. 0% of cases with non-CR, P=0.07). Conclusion: Disease status at HDCT/autoPBSCT tended to influence survival. Further studies are necessary to define the role of HDCT/autoPBSCT and to identify subgroup of patients who might benefit from this investigational treatment.
Hyeong Gon Yu,Hum Chung,Young Suk Yu,Jong Mo Seo,Jang Won Heo 대한안과학회 2003 Korean Journal of Ophthalmology Vol.17 No.1
AlamarBlue is used to induce color and fluorescence in the microenvironment of activated cells. The alamarBlue assay was studied to determine if it could be used as a method of evaluating the number of retinal pigment epithelial (RPE) cells. A series of two-fold dilutions of RPE cells were placed into 96-well culture plates. The alamarBlue was added to the culture media after attaching the cells. The absorbance and fluorescence were measured consecutively at various intervals over a period of 24 hr. Cell viability were evaluated by means of the trypan blue exclusion method and flow cytometry using a combination of propidium iodide and annexin V was done to prove the safety of alamarBlue assay to the cells. Both the absorbance and the fluorescence had a linear relationship with the number of RPE cells. Exposing the RPE cells to alamarBlue was not detrimental to the cells. In conclusion, the alamarBlue assay constitutes a one-step, extremely simple, reproducible, economical and non-toxic procedure for evaluating the number of viable RPE cells.
Poster Session:PS 1168;Cardiology:J Point Change During Supraventricular Tachycardia
( Hyeong Won Seo ),( Ki Hong Lee ),( Hyung Wook Park ),( Jeong Gwan Cho ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
A 54-year-old man presented with frequent episodes of sudden palpitation. Electrocardiogram demonstrated a narrow QRS complex tachycardia with a rate of 150/min. During the tachycardia that J point of the QRS complex occasionally became deeper and sharper(figure1). Electrophysiologic study was performed. A narrow QRS complex tachycardia was reproducibly induced by a single atrial extrastimulus. The tachycardia showed an intermittent change of the J point (figure 2). Atrial activity at the high right atrium (HRA) always preceded those of the His bundle and coronary sinus (CS) during the fi rst SVT with an atrial cycle length of 344 ms, but retrograde atrial activation sequence in the CS electrograms changed occasionally. The activation of right anterolateral and left lateral accessory pathway (AP) made the J point deeper and sharper than right anterolateral AP activation alone. Radiofrequency catheter ablation could abolish conduction over right side AP. A single ventricular extrastimulus induced the second tachycardia (388 ms) with the earliest, consistent retrograde atrial activity at distal CS. Electrocardiographic or electrophysiologic fi ndings that demonstrate the multiple AP include 1) changing antegrade delta waves; 2) evidence of multiple routes of retrograde atrial activation; 3) orthodromic SVT with intermittent antegrade fusion complexes. 1 In our instance, additional AP could be recognized by more than one atrial breakthrough points. Here were intermittent changes of retrograde atrial activation sequence in the CS while retrograde atrial activation in the HRA was earliest. The constantly earliest activation in the HRA suggests the clinical SVT uses the right anterolateral AP as a reentry circuit and intermittently the left lateral AP as a bystander. Atrial fusion due to intermittent activation of the two accessory pathways changed the J point on the electrocardiogram. Careful attention to the J point during the tachycardia could help identify multiple accessory pathways before electrophysiologic study.
Effect of Friction Modifier on Rolling Contact Fatigue and Wear of Wheel and Rail Materials
Seo, Jung-Won,Jun, Hyun-Kyu,Kwon, Seok-Jin,Lee, Dong-Hyeong unknown 2018 Tribology transactions Vol.61 No.1
<P>In this study, the effects of a friction modifier (FM) on wear and rolling contact fatigue were investigated by twin-disc testing under various conditions. It was found that the contact fatigue damage occurred on the rail specimen under the FM condition and the water condition. The test under FM condition was performed under three different spraying times: 0.2, 0.5, and 1.0 s. The progress of contact fatigue damage severely increases at a spraying time of 0.2 s. Contact fatigue damage under the FM condition occurred faster than that under the water condition. Results show that the friction modifier induced a mixed condition that exists at the same time as the wet condition and the dry condition. Cracks were initiated by the traction force due to the friction of the dry condition and the crack growth rate became faster due to the fluid entrapment mechanism under the wet condition. Therefore, the amount of FM should be evaluted to avoid severe contact fatigue damage.</P>
Fatigue Crack Growth and Fracture behavior of Rail Steels
Seo, Jung Won,Kwon, Seok Jin,Lee, Dong Hyeong,Kwon, Sung Tae,Choi, Ha Yong The Korean Society for Railway 2012 International Journal of Railway Vol.5 No.3
Contact fatigue damages on the rail surface, such as head checks and squats are a growing problem. The fatigue cracks forming on the contact surface grow according to load and lubricating conditions and may end up breaking the rail. Rail fracture can be avoided by preventing the cracks from reaching the critical length. Therefore, the crack growth rate needs to be estimated precisely according to the conditions of the track and load to develop a maintenance plan against rail damages. Therefore, it is important to understand the mechanism of cracks initiation and growth on a rail due to repetitive rolling contact. In this study, we have investigated the crack growth behavior on the rail surface by using the twin-disc tests and the finite element analysis.
Seo, Moon-Hyeong,Han, Jieun,Jin, Zongwen,Lee, Dong-Won,Park, Hee-Sung,Kim, Hak-Sung American Chemical Society 2011 ANALYTICAL CHEMISTRY - Vol.83 No.8
<P>Immobilization of proteins in a functionally active form and proper orientation is crucial for effective surface-based analysis of proteins. Here we present a general method for controlled and oriented immobilization of protein by site-specific incorporation of unnatural amino acid and click chemistry. The utility and potential of this method was demonstrated by applying it to the analysis of interaction between a pathogenic protein DrrA of <I>Legionella pneumophila</I> and its binding partner Rab1 of human. Kinetic analysis of Rab1 binding onto the DrrA-immobilized surfaces using surface plasmon resonance revealed that immobilization of site-specifically biotinylated DrrA results in about 10-fold higher sensitivity in binding assay than the conventional immobilization of DrrA with random orientation. The present method is expected to find wide applications in the fields of the surface-based studies of protein−protein (or ligand) interactions, drug screening, biochip, and single molecule analysis.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2011/ancham.2011.83.issue-8/ac103334b/production/images/medium/ac-2010-03334b_0002.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ac103334b'>ACS Electronic Supporting Info</A></P>
Fatigue Design Evaluation of Railway Bogie with Full-Scale Fatigue Test
Seo, Jung-Won,Hur, Hyun-Moo,Jun, Hyun-Kyu,Kwon, Seok-Jin,Lee, Dong-Hyeong Hindawi Limited 2017 Advances in materials science and engineering Vol.2017 No.-
<P>The bogie frame of a railway is an important structural member for the support of vehicle loading. In general, more than 25 years’ durability is necessary. Much study has been carried out in experimental and theoretical domains on the prediction of the structural integrity of the bogie frame. The objective of this paper is to estimate the structural integrity of the bogie frame of an electric railcar. Strength analysis has been performed by finite element analysis. From this analysis, stress concentration areas were investigated. To evaluate the loading conditions, dynamic stress was measured by strain gauge. It has been found that the stress and strain due to the applied loads were multiaxial conditions according to the location of the strain gauge. Fatigue strength evaluations of the bogie frame were performed to investigate the effect of a multiaxial load through the employment of a critical plane approach.</P>