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( Gun Wung Na ),( Sang Goon Shim ),( Kil Jong Yu ),( Dae Hyeon Cho ),( Chang Uk Jeong ),( Ji Eun Oh ),( Hyun Chin Cho ),( Kwang Min Kim ),( Hyoun Soo Lee ),( Man Je Park ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: In men, erectile dysfunction (ED), which is defi ned as the inability to achieve or maintain an erection suffi cient for satisfactory sexual performance, is an important issue. There were extensive investigations in clinical and pathophysiological mechanisms with sexual dysfunction during the last decade. However, ED in patients with chronic viral hepatitis has been investigated in few and limited studies, which are often not comparable because they use different survey and patient-sampling methodologies. Moreover, few have evaluated the association of ED and depression in patients with chronic viral hepatitis. Therefore, we assessed the prevalence of ED, and their association with depression in patients with chronic viral hepatitis. Methods: This cross-sectional study was conducted from August 2013 through January 2014. All outpatients with chronic viral hepatitis between the age of 18 and 80 years were considered eligible. The exclusion criteria included well established causes of erectile dysfunction such as liver cirrhosis and alcohol abuse. Erectile dysfunction was assessed with the International Index of Erectile Function-5 (IIEF-5) scale. The Beck Depression Inventory (BDI) scale was used to assess depression of the patient. Results: The prevalence of erectile dysfunction among the patients with chronic viral hepatitis was 40%. Age, employment, peg-interferon, IIEF-5 scores and BDI scores were statistically associated with erectile dysfunction. And also, IIEF-5 scores correlated negatively with age, employment and BDI scores. In a multiple logistic regression analysis, age and depression were independently associated with erectile dysfunction. Conclusions : Patients with chronic viral hepatitis have a high prevalence of erectile dysfunction. Age and depression are independent factors of erectile dysfunction in male patients with chronic viral hepatitis. Evaluation of depression must be included to properly manage erectile dysfunction.
상기도 기침증후군에서 만성 기침에 대한 비강 내 스테로이드제의 영향
나건웅 ( Gun Wung Na ),이동규 ( Dong Gyu Lee ),김준영 ( Jun Young Kim ),박원일 ( Won Il Park ),이경빈 ( Kyung Been Lee ),이원재 ( Won Jae Lee ),김정은 ( Jeong Eun Kim ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.5
Purpose: Although upper airway cough syndrome (UACS) is one of the most common causes of chronic cough, there are few reports on the effects of intranasal steroids (INS) on improvement of cough in patients with chronic cough caused by UACS. Here, we observed improvement in cough depending on prescribed medications, including INS, in patients with chronic cough caused exclusively by UACS in the clinical setting. Methods: Patients with chronic cough caused exclusively by UACS were selected by the retrospective review of medical records. Durations and kinds of prescribed medications, nasal and postnasal drip symptoms, and results of paranasal sinus series at first visit were evaluated. According to the improvement of cough at the second visit, the patients were divided into the improved and unimproved groups. Odds ratios of each medication in the improved group were analyzed by logistic regression adjusted for age, sex, smoking history, duration of treatment, prescriptions of medications, presence of nasal and postnasal drip symptoms, and results of paranasal sinus series. Results: A total of 122 patients with chronic cough caused exclusively by UACS were comprised of 38 patients in the improved group and 84 patients in the unimproved group. INS were prescribed to 45 patients, and the number of patients with INS prescription were significantly higher in the unimproved group than that in not-improved group (55.3% vs. 28.6%, P=0.008). The odds ratio of INS prescription was significantly higher in the improved group (odds ratio, 4.78; 95% confidence interval, 1.03-22.3; P=0.046). Conclusion: INS could improve cough symptom in patients with UACS. These results warrant further evaluation.(Allergy Asthma Respir Dis 2014;2:362-369)
( Jun Young Kim ),( Jin Dong Kim ),( Kyung Bin Lee ),( Won Jae Lee ),( Gun Wung Na ),( Wonil Park ),( Hyoun Wook Lee ),( Jun Ho Ji ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
It is needed to distinguish between primary lung cancer and metastatic lung cancer in solitary lung nodule detected in patient with history of another solid cancer. But in case of multiplel lung nodules, we generally tend to consider the lung lesions as a metastatic lesion without biopsy. A 62 years old male presented with two tiny lung nodules (each nodule was located on each lung) which were detected after 18 months of right nephrectomy for renal cell carcinoma. At that time, the lesions were considered as metastatic renal cell carcinoma without biopsy by the attendant doctor. Although targeted therapies of RCC were given, the lung lesion was progressed and then the patients came to our hospital. We tried biopsy of the larger lung nodule and the pathologic result confirmed primary lung squamous cell carcinoma. So surgical resection was performed and pathologic staging revealed pT1N0. Contralateral lung nodule was too small to take biopsy, we decided to take close observation. Several months later, size of the remnant lung nodule was increased and biopsy was performed. At this time, the result was proven metastatic renal cell carcinoma and until now, he is taking everolimus everyday. We present a confused case of concurrence of metastatic lung cancer with a primary lung cancer.
Jun Young Kim(김준영),Jin Dong Kim(김진동),Kyung Bin Lee(이경빈),Won Jae Lee(이원재),Gun Wung Na(나건웅),Wonil Park(박원일),Gi Cheol Park(박기철),Tae Gyu Kim(김태규),Jun Ho Ji(지준호) 대한두경부종양학회 2014 대한두경부 종양학회지 Vol.30 No.1
비인두암에서 시행되는 방사선 치료 이후에 구강건조증과 피부 변화는 흔하게 볼 수 있는 합병증 중 하나이다. 비인두암의 좋은 예후를 고려할 때, 그러한 치료와 관련된 독성들은 상대적으로 오랫동안 문제를 야기하며 삶의 질 저하를 불러온다. 특히 류마티스 관절염, 루푸스와 같은 결합조직 질환을 가진 환자들에게서 방사선 치료를 시행하였을 때, 빈번하게 심각한 독성이 관찰된다. 본 증례는 성인형 스틸씨 병에서 병발된 비인두암의 치료로 항암방사선 동시 치료를 실시한 결과, 비교적 경미한 구강 건조, 점막염, 불면증 등의 합병증이 관찰되었으나, 완전 관해가 획득되었다. 이에 저자들은 과거에 보고된 적 없는 성인형 스틸씨 병에 병발한 비인두암의 치료 경험을 다른 결합조직질환들에서 방사선 치료의 문헌들과 함께 보고하는 바이다.
성인형 스틸씨 병에서 병발된 비인두암의 치료 및 문헌 고찰
김준영,김진동,이경빈,이원재,나건웅,박원일,박기철,김태규,지준호,Kim, Jun Young,Kim, Jin Dong,Lee, Kyung Bin,Lee, Won Jae,Na, Gun Wung,Park, Wonil,Park, Gi Cheol,Kim, Tae Gyu,Ji, Jun Ho The Korean Society for Head and Neck Oncology 2014 대한두경부 종양학회지 Vol.30 No.1
비인두암에서 시행되는 방사선 치료 이후에 구강건조증과 피부 변화는 흔하게 볼 수 있는 합병증 중 하나이다. 비인두암의 좋은 예후를 고려할 때, 그러한 치료와 관련된 독성들은 상대적으로 오랫동안 문제를 야기하며 삶의 질 저하를 불러온다. 특히 류마티스 관절염, 루푸스와 같은 결합조직 질환을 가진 환자들에게서 방사선 치료를 시행하였을 때, 빈번하게 심각한 독성이 관찰된다. 본 증례는 성인형 스틸씨 병에서 병발된 비인두암의 치료로 항암방사선 동시치료를 실시한 결과, 비교적 경미한 구강 건조, 점막염, 불면증 등의 합병증이 관찰되었으나, 완전 관해가 획득되었다. 이에 저자들은 과거에 보고된 적 없는 성인형 스틸씨 병에 병발한 비인두암의 치료 경험을 다른 결합조직질환들에서 방사선 치료의 문헌들과 함께 보고하는 바이다.