제2형 당뇨병 환자의 비타민 B 섭취와 임상지표의 상관관계에 대한 연구

심유진,권지영,정혜연 한국식생활문화학회 2020 韓國食生活文化學會誌 Vol.35 No.5

The objective of this study was to investigate the effects of dietary vitamin B intake on biomarkers related to lipidmetabolism, inflammation and blood glucose control, that are important in the development of type 2 diabetes and itscomplications. Seventy-six adults (42 males, 34 females) were recruited from a group of diabetes patients who had visitedthe medical center for treatment. Data on anthropometric characteristics and dietary intake of thiamine, riboflavin, niacin,vitamin B6 and folate were collected using 24-hour diet recall and the CAN Pro 4.0 program. Also, data on clinical indicessuch as serum lipids, blood pressure, high-sensitivity C-reactive protein (hs-CRP), hemoglobin A1c (HbA1c) andhomeostasis model assessment 2-insulin resistance (HOMA2-IR) were collected and analyzed for correlation with dietaryvitamin B intake. Results from the dietary intake survey showed that riboflavin and folate intake (in males) and folate intake(in females) were below the Dietary Reference Intake for Koreans. Statistical analysis revealed a negative correlationbetween hs-CRP and dietary intake of B vitamins. Riboflavin intake was inversely associated with systolic blood pressureafter adjustments for age, BMI, smoking, alcohol consumption, exercise, ingestion of diabetes mellitus medication andenergy intake (p<0.05). Our results suggest that dietary vitamin B may influence inflammation and consequently may helpin better management of type 2 diabetes.

제2형 당뇨병 환자의 칼슘 섭취가 혈중지질, 혈압, 염증 및 혈당 관련 지표에 미치는 영향

정혜연,Chung, Hae-Yun 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.2

This study was conducted to determine the association between dietary calcium intake and biomarkers related to lipid and glucose metabolism and inflammation in Korean patients with type 2 diabetes. Seventy-five subjects (41 males, 34 females) were recruited from a group of patients who had visited the department of endocrine medicine. Data on anthropometric characteristics, clinical indices such as hemoglobin A1c and C-reactive protein (CRP), and dietary nutrient intakes were collected. Subjects were divided into three groups on the basis of their calcium intake [< EAR (below estimated average requirement), EAR-RNI (between EAR and recommended nutrient intake), > RNI (above RNI)]. Average calcium intake of < EAR, EAR-RNI, > RNI groups were $462.7{\pm}18.7$, $649.7{\pm}12.8$, and $895.7{\pm}21.7mg$, respectively. Energy intake was not different among groups but intakes of protein, total and saturated fatty acids were significantly higher in > RNI group than < EAR group. Analysis of covariance revealed that HDL cholesterol level was significantly higher in EAR-RNI group, as compared to < EAR group after adjustment with confounders such as age, sex, BMI and energy intake (p < 0.05). Levels of CRP and homeostasis model assessment 2-insulin resistance (HOMA2-IR) were significantly lower in EAR-RNI group. Total cholesterol level was higher in EAR-RNI and > RNI groups, although within the normal range. Our results suggest that dietary calcium intake may influence the levels of HDL-cholesterol, CRP and HOMA2-IR and subsequently, help management/treatment of type 2 diabetes patients.

A review of recent evidence of dietary protein intake and health

Yoon Jung Park,Sangwon Chung,Jin-Taek Hwang,Jinyoung Shon,Eunjung Kim 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.no.sup1

The Korea National Health and Nutrition Examination Survey of 2013 to 2017 reported that the average protein consumption of the Korean population is above the current recommended nutrient intake of protein proposed by the Dietary Reference Intakes for Koreans. Some health professionals and the media often advise consuming diets high in protein for promoting metabolic regulation, weight control, and muscle synthesis. However, due to lack of scientific evidence, the validity and safety of high protein consumption are yet to be fully ascertained. The present review assesses recent evidence published in 2014-2020 from human studies, focusing on adequate protein intake and protein sources for the prevention of chronic diseases, particularly metabolic disorders and sarcopenia.

성인여성에서 열량공급원과 비만도의 관련성 -4회 실시한 3일간의 식이기록 평균을 토대로-

신명희,윤미옥,남석진,송윤미,Shin, Myung-Hee,Yoon, Mi-Ock,Nam, Seok-Jin,Song, Yun-Mi 대한예방의학회 2007 예방의학회지 Vol.40 No.1

Objectives : The aim of this study was to investigate the relationship between the contributions of macronutrients to the total energy intakes and Body Mass Indices (BMI, $kg/m^2$) of Korean women. Methods : We used dietary records data from 115 healthy Korean women, ages 20 and over, who completed four 3-day dietary records between February 2003 and March 2004. For the calculation of nutrients we used a dietary assessment program developed by the Korean Nutritional Society. Macronutrient intakes were estimated by averaging individual total daily intakes in four 3-day dietary records. Subjects were categorized into three Body Mass Index (BMI) groups : underweight (BMI < 20), normal (20 $\leq$ BMI < 25), and overweight (BMI $\geq$ 25) group. Results : The total energy intakes were not different among the three BMI groups. Similarly, other macronutrient intakes such as protein, fat, carbohydrate, vegetable protein, animal protein, saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids were not different. From the multivariate nutrient density model, substituting polyunsaturated fatty acid for carbohydrate was positively associated with BMI in women aged 20 to 49 ($\beta=2.31$, p<0.01). In women aged 50 and over, substituting animal protein for carbohydrate was positively associated with BMI ($\beta=0.549$, p=0.04). Conclusions : No single macronutrient was associated with BMI when all subjects were combined. However, when stratified by age, polyunsaturated fatty acid intake in younger women, and animal protein intake in older women, were positively associated with BMI. In the future, we recommend a larger study to confirm these results.

Effects of Dietary Protein Level on Dry Matter Intake, and Production and Chemical Composition of Velvet Antler in Spotted Deer Fed Forest By-product Silage

Jeon, B.T.,Kim, M.H.,Lee, S.M.,Moon, S.H. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.12

The aim of this study was to provide basic information to allow improved nutritional management for velvet production by investigating the effects of dietary protein levels on dry matter intake and production and chemical composition of velvet antler in spotted deer (Cervus nippon). Twenty-four spotted deer stags were assigned to 4 unreplicated groups, Control (15% CP in diet, higher dry matter), CP10 (10% CP), CP15 (15% CP) and CP20 (20% CP). The velvet antlers were harvested from each stag on the 55th day after casting of the buttons from the previous set, measured for their size and weight, and the chemical composition of each antler was determined in three sections (top, middle, and base). Dry matter (DMI) and crude protein (CPI) intake were highest (p<0.05) for the Control and increased progressively (p<0.05) with increasing dietary protein level. Although not significant, mean length and girth of the main antler beam tended to be larger in either left or right beam with increasing protein level in the diet, longest in CP20 and shortest in CP10. Velvet antler production was lowest in CP10 and highest in CP20, which differed significantly (p<0.05). Only negligible differences were found between groups in chemical composition. It is concluded that dietary protein clearly influenced dry matter intake and velvet antler production, whereas there was comparatively little effect of dietary protein on chemical composition of antler in spotted deer.

제2형 당뇨병 환자의 영양소 섭취와 임상지표의 상관성에 관한 연구

권지영,정혜연,Kwon, Ji-Young,Chung, Hae-Yun 한국식품영양학회 2013 韓國食品營養學會誌 Vol.26 No.4

The objective of this study is to investigate the effects of dietary nutrient intakes for markers of blood glucose and inflammation which is important to the progress of type 2 diabetes and the development of its complications. For this study, 76 adults with diabetes (42 males, 34 females) were recruited from a group of patients who had visited the department of endocrine medicine. Data on anthropometric characteristics, clinical indices such as hemoglobin A1c (HbA1c) and C-reactive protein (CRP), and dietary nutrient intakes were collected. Our results have shown that 66% of subjects were either overweight or obese. Serum analysis indicates that levels of C-peptide, glucose, HbA1c, CRP, triglyceride, LDL-cholesterol were higher than normal range. Results from the dietary nutrient intake survey displayed that intakes of cholesterol and sodium were higher than Dietary Reference Intakes for Koreans. On the contrary, folate intake was lower than the guideline. Within the females, energy contribution from carbohydrate was higher than Korean Diabetes Association guideline. Statistical analysis has revealed a negative correlation between serum HbA1c level and dietary intakes of polyunsaturated fatty acid (PUFA), n-3 PUFA, ${\beta}$-carotene and vitamin E after adjustments for age, BMI, smoking habits, alcohol consumption, exercise and ingestion of diabetes mellitus medication (p<0.05). Serum CRP level was inversely associated with dietary intakes of carbohydrate, protein, vitamin C and fiber (p<0.05). Our results suggest that dietary nutrient intakes may influence the levels of HbA1c and CRP, and subsequently, it may help in the management/treatment of type 2 diabetes.

A review of recent evidence of dietary protein intake and health

Park Yoon Jung,Chung Sangwon,Hwang Jin-Taek,Shon Jinyoung,김은정 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.3

The Korea National Health and Nutrition Examination Survey of 2013 to 2017 reported that the average protein consumption of the Korean population is above the current recommended nutrient intake of protein proposed by the Dietary Reference Intakes for Koreans. Some health professionals and the media often advise consuming diets high in protein for promoting metabolic regulation, weight control, and muscle synthesis. However, due to lack of scientific evidence, the validity and safety of high protein consumption are yet to be fully ascertained. The present review assesses recent evidence published in 2014–2020 from human studies, focusing on adequate protein intake and protein sources for the prevention of chronic diseases, particularly metabolic disorders and sarcopenia.

The Effect of Dietary Intake of the Acidic Protein Fraction of Bovine Colostrum on Influenza A (H1N1) Virus Infection

Mei Ling Xu,김형진,장돈용,김홍진 한국미생물학회 2013 The journal of microbiology Vol.51 No.3

Acidic protein levels in the milk decrease markedly as lactation progresses, suggesting that it is an important part of the colostrum. However, little attention has been paid to their biological function. In this study, we isolated the acidic protein fraction of bovine colostrum (AFC, isoelectric point <5) by anion-exchange chromatography, and investigated the effect of its dietary intake on influenza A (H1N1) virus infection. 100% of mice infected with 1 LD50 of the virus survived when administered AFC for 14 days prior to infection, compared with 33% survival when administered phosphate buffered saline (PBS). Moreover, consumption of AFC reduced the weight loss associated with infection. We propose that dietary intake of AFC has a prophylactic effect on influenza A virus infection.

혈액투석환자의 식이조사 및 Protein Catabolic Rate에 관한 연구

장유경(Chang Yu-Kyung),진윤경(Jin Yun-Gyung),박한철(Park Han-Chul) 韓國營養學會 1992 Journal of Nutrition and Health Vol.25 No.3

흰쥐에서 식이 단백질 수준이 유즙 성분과 새끼의 영양상태에 미치는 영향

김화영(Kim Wha Young),김지윤(Kim Jee Yoon),홍경희(Hong Kyoung Hee),이현숙(Lee Hyun Sook) 韓國營養學會 1999 Journal of Nutrition and Health Vol.32 No.8