성소의 제거와 고콜레스테롤 식이 급여가 흰쥐의 혈장과 간의 콜레스테롤, 중성지방 수준과 혈소판 응지성 및 간 조직에 미치는 영향에 있어서 암·수의 차이

강정숙 제주대학교 방사능이용연구소 2002 연구보고 Vol.16 No.-

Gender differences in the effects of gonadectomy and high cholesterol diet on body weight and body cholesterol were investigated by using Sprague Dawley rats. Body weight, plasma and liver levels of cholesterol and triglyceride and platelet aggregation were examined in ovariectomized (OVX) or orchidectomized (ODX) rats with their intacts after feeding diet with or without 0.5% cholesterol. Body weight was significantly increased (P<0.01) in OVX rats and significantly decreased (P<0.01) in ODX rats compared to their respective intact rats, and cholesterol diet significantly (P<0.05) decreased body weight in gonadectomized rats. Liver lobes from rats fed cholesterol diet were opaque and larger than those from rats fed control diet, resulting in a significant increase (P<0.01) in LW/BW ratio. Plasma and liver levels of total cholesterol were significantly increased (P<0.01) in female rats regardless ovariectomy when fed 0.5% cholesterol diet, but those levels in male rats were increased only when they were orchidectomized (P<0.01). Plasma HDL-cholesterol was significantly decreased (P<0.05) in both sexes when fed cholesterol diet. HDL-cholesterol were higher in female than male rats regardless treatments (P<0.05). Liver triglyceride was significantly increased (P<0.05) in both sexes when fed cholesterol diet. Plasma level of triglyceride was not different among groups except significant decrease (P<0.05) in cholesterol fed ODX rats. Maximum platelet aggregation in female rats was significantly lower (P<0.05) than male, but ovariectomy and cholesterol diet casused an increase to the level of male rats. Microscopic examination showed cholesterol diet caused a lipid accumulation in liver. Results indicate that intact female rats have higher response to hypercholesterolemic diet than intact male rats and orchidectomy causes male rats more responsive to hypercholeserolemic diet. However. ovariectomy causes an increase female food efficiency ratio to the level of male rats, significantly increasing body weight.

Efficacy of and Patient Compliance with a Ketogenic Diet in Adults with Intractable Epilepsy: A Meta-Analysis

Fang Ye,Xiao-Jia Li,Wan-Lin Jiang,Hong-Bin Sun,Jie Liu 대한신경과학회 2015 Journal of Clinical Neurology Vol.11 No.1

Background and Purpose Despite the successful use of a ketogenic diet in pediatric epilepsy, its application in adults has been limited. The aim of this meta-analysis was to summarize thefindings of relevant published studies in order to identify the efficacy of and compliance with aketogenic diet and its main subtypes (i.e., classic ketogenic diet and modified Atkins diet) inadults with intractable epilepsy, and to provide useful information for clinical practice. Methods Electronic searches of PubMed, EMBASE, Google Scholar, and the ISI Web of Science were conducted to identify studies of the efficacy of and patient compliance with a ketogenic diet in adults with intractable epilepsy; the included studies were reviewed. Meta-analyseswere performed using STATA to determine combined efficacy rates and combined rates of compliance with the ketogenic diet and its main subtypes. Results In total, 12 studies qualified for inclusion, and data from 270 patients were evaluated. The results of the meta-analysis revealed combined efficacy rates of all types of ketogenic diet,a classical ketogenic diet, and a modified Atkins diet were 42%, 52%, and 34%, respectively;the corresponding combined compliance rates were 45%, 38%, and 56%. Conclusions The results indicate that a ketogenic diet is a promising complementary therapyin adult intractable epilepsy, and that while a classical ketogenic diet may be more effective,adult patients are likely to be less compliant with it than with a modified Atkins diet.

The Status of Dysphagia Diet and Its Prescription in Korea

송윤범,최경효,김동규,김하정,강은희 대한연하장애학회 2013 대한연하장애학회지 Vol.3 No.1

Objective: The patient with dysphagia needs special care, especially on diet. Since there is no guideline for dysphagia diet in Korea, survey on the status of dysphagia diet and its prescription is needed as basic information for dysphagia diet guideline. Method: The survey form was delivered to 80 hospitals and 58 hospitals replied the survey. The questions were composed to determine whether the hospitals have a standardized manual for dysphagia diet; whether the hospitals have staged diet; what material is used to modify the thickness of the food; which criteria are used to distinguish each diet; what is the basis of the dysphagia diet prescription; whether they have a team approach in prescribing diets for dysphagia patients; and whether they have individual information on diet or on nutrition materials provided to the patients. The secondary analysis was done for the dichotomic questions through chi-square test. Result: Among 58 hospitals, 48 hospitals prescribed a dysphagia diet (82.8%). Among these, 45 hospitals had the staged diet (93.8%). Twenty-three had manual for dysphagia diet (47.9%). Thirty-one prescribed a diet on the basis of objective tests (64.6%). Seventeen prescribed a diet according to non-objective opinion such as a doctor’s opinion (35.4%). Twenty-nine had a team approach to dysphagia patients (60.4%). Thirty-five had individual information on diet (72.9%). Among these, 19 had references (54.3%). The number of beds and grade of hospitals were analyzed on secondary analysis. The dysphagia diet menu was less prepared at secondary (31.0%). The information material was not prepared on both secondary (30.0%) and relatively small hospitals (42.9%). Conclusion: Based on this survey, it is necessary to develop standard manual in making dysphagia diet. We should have more attention on the team approach. We need to introduce the valid references to the information which is given to the patients. (JKDS 2013;3:26-31)

한국 여대생들의 다이어트 인식에 대한 개념도 분석

이상희,오보영 한국여성심리학회 2018 한국심리학회지 여성 Vol.23 No.2

Despite the reality that many people are doing diet, conceptualization of what diet people think of diet is not yet realized. In this study, we aimed to clarify the conceptual structure of diet recognition by using concept mapping analysis for female college students who ever diet before. For this purpose, 15 female college students from Seoul were selected as participants and their ideas on diet were collected and then the contents were classified into 68 statements. Then, based on the statement data classified by the participants, multidimensional scaling analysis and hierarchical clustering analysis were performed. As a result, a conceptual diagram of 8 clusters according to two dimensions was derived. Each cluster is divided into three categories: 'experience of failure to control food during diet', 'personal diet method', 'desire to fit idealized body image', 'personal motivation and goal to perform diet', ' Emotions', 'various failures experienced during diet', 'interpersonal problems caused by diet', and 'concept and definition of diet'. In addition, the two dimensions that classify the 8 clusters are the 'psychological factor dimension - experiential behavior factor' dimension and 'ideal behavior dimension – failure of psychological and behavioral control' respectively. Based on the significance level of each participant 's statements, the most important group of participant' s concept was 'Diet concept and definition'. Finally, the limitations of this study and suggestions for future research are suggested.

사상인 식이법이 8체질 식이법의 형성에 미친 영향에 대한 고찰

정용재,박성식,Jeung, Yong-Jae,Park, Seong-Sik 사상체질의학회 2011 사상체질의학회지 Vol.23 No.2

1. Objectives: This study intends to identify the contents of Sasang Constitutional Diet through a book by Lee Je-Ma, to review the implied contents, and to analyze the influence of this information and principles on the formation of Eight Constitutional Diet. 2. Results and Conclusions: 1) The Sasang Constitutional Diet was systematically established by Lee Je-Ma, and is composed by the principles of 'food is on different from medicine(食藥同源)', principles of 'reinforcement of one organ(一臟補强)', principles of 'should not be mixed(混用不可)' and principles of 'food abstinence'(飮食節制)'. 2) The Eight Constitutional Diet has already been studied before 1962, and "Classification Of Constitutional Regimen and Diet", which recorded harmful and good food, has been used in clinical practices since 1962. The basis that can transform Eight Constitutional Diet into Sasang Constitutional Diet can be found in the fact that the Eight Constitution is based on the Sasang constitution. However, because clinical research on the relationship between 8 constitution and Sasang constitution is still sketchy, directly transforming the current Eight Constitutional Diet into Sasang Constitutional Diet seems unreasonable.

밥 식이와 빵 식이가 지구성 운동 후 혈중 중성지방, 인슐린 및 그렐린에 미치는 영향

유동훈(Dong-Hun Yoo),하태열(Tae-Yeol Ha),안지윤(Ji-Yoon Ahn),정현령(Hyun-Lyung Jung),강호율(Ho-Youl Kang) 한국식품영양과학회 2012 한국식품영양과학회지 Vol.41 No.8

In this study, the effects of a rice diet and bread diet on plasma triglyceride, insulin and ghrelin levels during low-intensity endurance exercise and recovery were investigated. Ten male students randomly received 2 different treatments: the rice diet and bread diet. On the first day, the participants performed 2 hours of treadmill running with 6% uphill at 50% VO2max after breakfast and then each consumed lunch and dinner. Blood samples were drawn 120 min before exercise and, right before exercise and, 60 min and 120 min after the start of exercise. On the second day, blood samples were drawn prior to breakfast, immediately after breakfast and, 60 min, 120 min, and 180 min after breakfast with no exercise treatment. Plasma triglyceride, ghrelin, glucose, and insulin levels were not significantly different between the two treatment groups on the first day. In addition, there was no difference in the carbohydrate and fat oxidation rate between the two treatments groups. However, plasma triglyceride levels in subjects that received the rice diet were significantly reduced by 14% when compared to subjects that received the bread diet at 180 min after consuming the breakfast diet on the second day. Ghrelin levels were significantly higher for subjects that received the rice diet than subjects that were given the bread diet. However, insulin in participants that consumed the rice diet was significantly lower than those that received the bread diet at 60 min and 120 min after consumption of the breakfast diet on the second day. Glucose levels in the subjects that were given the rice diet were significantly reduced by 10.3% when compared with participants that received the bread diet at 60 min. Therefore, the results of the study showed that a rice diet may be more effective in preventing cardiovascular diseases than a bread diet when combined with exercise.

SBY-Ⅲ이 비만 및 비만 후 식이조절 흰쥐에 미치는 영향

우경하 ( Kyung Ha Woo ),정석희 ( Seok Hee Chung ),이종수 ( Jong Soo Lee ),김성수 ( Sung Soo Kim ),신현대 ( Hyun Dae Shin ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.2

Objectives : This experimental study was designed to investigate the effect of SBY-Ⅲ extract on the weight, cell size of epididymal fat-pad, fat accumulation area in liver, serum lipid level and UCP1 mRNA in brown adipose tissue of high fat diet-fed obese rats continued by high fat diet and regulated by normal Diet Methods : The body weight gain, weight of the internal organs(epididyrmis, liver, brown adipose tissue), insulin, triglyceride, total cholesterol, total lipid, free fatty acid, expression of UCP1 mRNA were measured in high fat diet-fed obese rats continued by high fat diet and regulated by normal diet. The experimental study are divided into exp-Ⅰand exp-Ⅱ. Each study was adminstered normal diet, high fat diet and SBY-Ⅲ according to each situation. Normal group is normal diet for 8 weeks. Exp-Ⅰ are divided into control group(high fat diet for 8 weeks) and sample group(high fat diet for 8 weeks and SBY-Ⅲ for last 2 weeks). Exp-Ⅱ are divived into control group(high fat diet for 6 weeks and normal diet for 2 weeks) and sample group(high fat diet for 6 weeks and normal diet with SBY-Ⅲ for 2 weeks). These were then compared mutually. Results : 1. Irrespective of diet control, sample group taken SBY-Ⅲ showed the more effective decrease of weight gain than control group and diet control-fed sample group with SBY-Ⅲ showed the more effective decrease of weight loss including weight gain than control group. 2. Irrespective of diet control, sample group taken SBY-Ⅲ showed the more effective decrease cell size of epididymal fat-pad, fat accumulation area in liver than control group. 3. Non diet control-fed sample group taken SBY-Ⅲ showed the more effective decrease of serum triglyceride, total lipid, free fatty acid than control group and diet control-fed sample group taken SBY-Ⅲ showed the decrease of serum triglyceride, free fatty acid than control group. 4. Only diet control-fed sample group taken SBY-Ⅲ showed the decrease of UCP1 volume. Conclusions : These results shows that SBY-Ⅲ has effects on anti-obesity, especially keeping pace with diet control.

고혈압 전단계 집단 식이보건교육이 식이습관과 혈압에 미치는 효과

심정하(Jeoung Ha Sim) 한국보건교육건강증진학회 2006 보건교육건강증진학회지 Vol.23 No.4

Objectives: The aim of this study was to investigate the effects of DASH diet and law salt diet health education program on the blood pressure and the diet habit in the prehypertension group in Korea. Methods: The participants in this study were 141 people with prehypertension who were seen at a public health center. Data collection was done from March i 1 to November 11, 2005 using interview with questionnaires. The participants took part in the diet health education program for 8 weeks. In order to evaluate the effectiveness of health education program, the variables of the diet such as hypertension, law salt diet and DASH diet were measured before and after the health education. The blood pressure was measured three times during the education. The collected data were analyzed with paired t-test and repeated ANOVA using SPSS 12.0 for Windows. Results: The diet habit variables after the education showed that their diet habit tend to the low salt diet and the DASH diet. The participants improved in their knowledge of hypertension and law salt diet, and they improved in the behavioral level of law salt diet and DASH diet after the health education for 8 weeks. Systolic and diastolic pressure were significantly decreased in prehypertension group after 8 weeks [10㎜Hg/6㎜Hg(p<0.001)]. Conclusion: These result suggest that the improvement in the level of behavior might be related with the change in blood pressure among the people having prehypertension in Korea.

여대생의 체질량지수, 다이어트 인식과 다이어트 행동에 관한 연구

이진희 한국응용과학기술학회 2020 한국응용과학기술학회지 Vol.37 No.3

The purpose of this study is to identify the BMI, diet perception and diet behavior of female university students. A descriptive survey design was used 165 students from October 29 to November 9, 2018. Data were analyzed using mean, ttest, ANOVA, cross analysis with SPSS 21.0. Total diet perception was 3.44 points, highest sub category was ‘practice’ with 4.00 points, followed by ‘information and education’ with 3.58 points, ‘necessity’ with 3.32 points and lowest category was ‘selfrecognition’ with 2.84. 65 students(43.0%) were ‘less than three times’ in ‘Number of diets’ and diet methods was 65(43.0%) for ‘food control’ and 62(41.1%) for ‘exercise’. During in a week, 98 students(84.9%) exercised within three hours, followed by 33(21.9%) who did not exercised at all. 22 students(14.6%) said they experienced damage from dieting, while the types included gastrointestinal disease, menstrual irregularity and hair loss. The total score of diet perception according to BMI was lower in the underweight group than in the normal and overweight groups(p<.001). In diet 'practice' category, low weight group scored lower than normal weight and overweight groups(p<.05). In 'information and education' category, overweight group scored the highest, followed by normal and underweight groups(p<.001). In diet 'necessity' and 'selfrecognition' categories, low weight group scored lower than normal weight and overweight groups(p<.001). Diet behavior by diet perception was different in number and method of diet(p<.001). Based on the results, it is thought that attention and education are needed to form a proper diet perception and maintain healthy living for female university students. 본 연구는 여대생의 체질량지수와 다이어트 인식 및 다이어트 행동에 관해 알아보기 위해 시행된 서술적 조사연구이다. 연구 대상자는 일 지역 여자대학교에 재학 중인 학생 165명으로 자료수집은 2018년 10월 29일부터 11월 9일까지 진행되었다. 수집된 자료의 분석은 SPSS/WIN 21.0 프로그램을 이용하여 기술통계, t 검정, 일원분산분석, 교차분석을 하였다. 전체 다이어트 인식은 3.44점이었고 요인별로는 ‘실행’이 4.00점으로 가장 높게 나타났고, 그 다음으로 ‘정보 및 교육’이 3.58점, ‘필요성’은 3.32점, ‘자가인식’은 2.84점으로 가장 낮게 나타났다. 다이어트 횟수는 ‘3회 미만’이 65명(43.0%)으로 가장 많았으며 방법은 ‘음식조절’이 65명(43.0%), ‘운동’이 62명(41.1%) 순이었다. 일주일간 운동시간은 3시간 미만이 99명(65.6%)으로 가장 많았고 ‘전혀 하지 않는다’가 32명(21.2%)으로 그 다음 순이었다. 다이어트로 인한 피해경험은 22명(14.6%)이 있다고 응답했고, 종류로는 위장병, 생리불순, 탈모 등이었 다. BMI에 따른 다이어트 인식 전체 점수는 저체중군이 정상체중 및 과체중군보다 점수가 낮게 나타났 다(p<.001). 하부 요인별로 보면 다이어트 ‘실행’은 저체중군이 정상체중 및 과체중군보다 점수가 낮게 나타났고(p<.05), 다이어트 ‘정보 및 교육’은 과체중군의 점수가 가장 높았고, 그 다음이 정상체중군, 저체중군 순이었다(p<.001). 다이어트 ‘필요성’과 ‘자가인식’은 저체중군이 정상체중 및 과체중군보다 점수가 낮게 나타났다(p<.001). 다이어트 인식에 따른 다이어트 행동은 다이어트 횟수와 방법에서 차이가 있었다(p<.001). 본 연구 결과를 토대로 여대생의 올바른 다이어트 인식 형성과 건강한 생활유지를 위한 관심과 교육이 필요하다고 사료된다.

REPULSIVE EFFECT AND PALATABILITY OF DIETARY PHENYLALANINE IN LAYING HENS

Choi, Y.-H.,Asakura, K.,Okumura, J.,Furuse, M. Asian Australasian Association of Animal Productio 1996 Animal Bioscience Vol.9 No.2

Food intake of birds can be affected by particle size as well as diet composition, In order to investigate whether food intake of diets including excessive amount of phenyalanine(Phe) was influenced by diet types. a series of experiments were conducted in growing chicks and laying hens. Growing chicks significantly decreased food intake in a semipurified excessive Phe diet compared with a semipurified control diet, while laying hens fed a practical diet including excess Phe did not significantly reduce their food intake over a corn starch-substituted control diet. In an attempt to find out whether diet type affects food intake in layers, the semipurified type diet with excess Phe greatly reduced food ingestion, but the effect was delayed in the practical type diet. Moreover, under choice feeding regimes between the Phe and either starch, tyrosine(Tyr) or fiber diets in order to investigate whether the decreased food intake in the presence of an excess of dieary Phe in laying hens is involved in the palatability for the diet, there was no significant difference between Phe and starch diet while a preference for the Phe diet tended to be increased when birds were offered Tyr. Laying hens ingested significantly more the Phe diet than the fiber diet within 1 h after feeding. For supporting the idea that preference for the Phe diet may be affected by manipulating taste sense, an anaesthetic or saline was intramuscularly administered under the tongue just before a choice feeding. Preference for the Phe diet was not significantly different from that for the fiber reference diet within 1 h in the anaesthetized birds while the birds preferred the Phe diet in the saline treated group. It is suggested that because birds are able to select a diet, the decreased food intake induced by dietary excess Phe may be due to the repulsive effect of Phe after ingestion but not the taste of Phe.