폐암환자에서 발생한 Clostridium difficile 대장염의 임상적 특성

( Chul Park1 ),( Ki Eun Hwang ),( Do Sim Park ),( Yu Ri Hwang ),( Chang Hwan Seoul ),( Hak Ryul Kim ),( Eun Taik Jeong ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.-

The rs196952262 Polymorphism of the AGPAT5 Gene is Associated with Meat Quality in Berkshire Pigs

Woo Bum Park,Sang Mi An,Go Eun Yu,Seulgi Kwon,Jung Hye Hwang,Da Hye Park,Deok Gyeong Kang,Tae Wan Kim. Hwa Chun Park1. Jeongim Ha*.,Chul Wook Kim* 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.6

High-quality meat is of great economic importance to the pig industry. The 1-acylglycerol-3- phosphate-O-acyltransferase 5 (AGPAT5) enzyme converts lysophosphatidic acid to phosphatidic acid in the mitochondrial membrane. In this study, we found that the porcine AGPAT5 gene was highly expressed in muscle tissue, influencing meat characteristics, and we also identified a non-synonymous single-nucleotide polymorphism (nsSNP) (rs196952262, c.673 A>G) in the gene, associated with a change of isoleucine 225 to valine. The presence of this nsSNP was significantly associated with meat color (lightness), lower cooking loss, and lower carcass temperatures 1, 4, and 12 h after slaughter (items T1, T4, and T12 on the recognized quality scale, respectively), and tended to increase backfat thickness and the waterholding capacity. These results suggest that nsSNP (c.673A>G) of the AGPAT5 gene is a potential genetic marker of high meat quality in pigs.

[논문]보육실습에서 프로젝트접근법에 대한 예비보육교사의 관심수준 변화 연구

유병민,박수홍,강문숙,박철수,정경훈 교육혁신학술위원회 2011 교육혁신연구 Vol.21 No.1

본 연구는 예비보육교사가 보육실습이라는 과정에서 프로젝트 접근법에 대한 관심은 어떠하며, 관심변화 여부를 사례중심으로 살펴보는 것을 목적으로 하였다. 이를 위하여 예비보육교사를 대상으로 보육실습 사전과 사후검사를 실시하였으며, 자세하고 구체적인 사실과 연구의 질적인 부분을 찾아보고자 인터뷰하였다. 그 결과, 첫째, 프로젝트에 대한 예비보육교사들의 관심은 전반적으로 무관심으로 나타났다. 둘째, 사전․사후검사 결과, 프로젝트 접근법에 대한 관심수준의 변화가 있었던 사례에서는 관심변화의 패턴도 다양하게 나타났으며, 관심변화가 크게 없었던 사례에서는 개인, 정보관심이 높게 나타났다. 이러한 결과는 프로젝트에 대한 예비보육교사의 관심수준은 보육환경, 보육과정, 실습지도 교사, 예비보육교사의 지각력, 프로젝트에 대한 사전지식이나 교육정도에 따라 다양하게 변할 수 있음을 알게 되었다. The purpose of this study is to analyze the case in which we can identify how the SoC of prospective child care teachers about the project approach changes and why these change appears during the child care practice when we assumpt that for prospective child care teachers to implement the project approach is that they participate in change during child care practice. In Case K, the SoC of the prospective child care teacher moves from Stage 0 awareness to Stage 2, Stage 3, Stage 4, and In Case M, the SoC moves from Stage 0 to Stage 1. In Case P, the SoC moves from Stage 1 to Stage 2, Stage 3, and in Case S, the SoC isn't changed. Above this, we identify the SoC of prospective child care teachers. Case K, M, and P changes SoC after child care practice, but Case S doesn't change. the reason why there is a difference is the mindset of prospective child care teachers. Anyone who wants to accomplish specific purposes can deal with diverse changes with flexibility, but others can easily have an effect on the changes. We suggest that instructor in organization for prospective child care teachers’ education need to have a class for prospective child care teachers to put theory into practice, give direct facilitation and intervention in the field to prospective child care teachers, make a learning environment for prospective child care teachers to make good use of teaching materials and instrument, develop guidebook for project approach and give support to prospective child care teachers.

철(Ⅱ)에 依한 클로로코발트(Ⅲ) 錯物의 還元反應에 關한 硏究

朴裕哲,吳相午 慶北大學校 文理科大學 1974 文理學叢 Vol.2 No.-

The kinetics and mechanisms for the reduction of cis-[Co(NH_3)_4H_2OCl]^+2 complexion by Fe^+2 have been investigated. The rate constants in various Fe^+2 concentration an the activation parameters of Co(Ⅲ)-Fe(Ⅱ) reaction have been measured at 14.1℃ and ionic strength of 1.0. It is estimated from a result of the entropy of activation (-43cal mole^-1 deg^-1 at 14.1℃) that the effect upon the surrounding solvent-the electrostriction effect-is a prime factor in determining the entropy of activation in this reaction. And all kinetic experiments were run under pseudo-first-order conditions with respect to Fe^+2 concentration. The reaction order in Fe^+2 varied from first order to zero order.

고압하에서 cyclotetramine 착이온(Cu-N_4^2+)과 음이온(S_2O_3^2-, SCN^-, I^- 및 NO_2^-)간의 화학평형반응

박유철,변종철 慶北大學校 1982 論文集 Vol.33 No.-

The equilibrium reactions between dl-5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-1,7-dienecopper(Ⅱ) complex ion and the basic ligands, L, given below have been investigated in a aqueous solution by using spectrophotometric method. Cu(dl-trans-1,7-diene)^2++L^n-??[Cu(dl-trans-1,7-diene)·L]^(2-n)+ In the reaction equation, L were S_2O_3^2-, SCN^-, I^- and NO_2^-. The absorption maximum of the complex ion, Cu(dl-trans-1,7-diene)^2+ shifted to longer wave-lengths in the above ligand solutions. The pressure effects on the chemical equilibrium were measured in the range of 1-1500 bar. The measurements of pressure effect on the absorption spectrum showed an decrease in an extinction coefficient with increasing pressure. At the room temperature, the equilibrium constants decreased with increasing pressure for anionic ligands, S_2O_3^2-, SCN^-, I^- and NO_2^- were 10.7, 2.4, 1.8 and 1.2 at 1 bar and 3.0, 1.0, 0.3 and 0.5 at 1,500 bar, respectively. The changes of reaction volume were the positives which are agreed with the trend of the reaction entropy changes. The pressures, at which are changes of reaction volume were no more appeared, were around 500 bar for SCN^- and NO_2^- ions, while were around 1,500 var for S_2O_3^2- and I^- ions. By comparing both the equilibrium constants experimentally determined and those calculated according to Fuoss's ion-pair equation, the deriving forces of the adduct formed, [Cu(dl-trans-1,7-diene)·L]^(2-n)+ were discussed.

산성수용액에서 cis-aquo-bis(ethylenediamine)cobalt(Ⅲ) 착이온의 평형 및 착이온과 oxalate이온간의 치환 반응에 미치는 압력 영향

박유철 慶北大學校 物理化學硏究所 1981 硏究論文集 Vol.1-2 No.-

The chemical equilibrium of cisaquo-bis(ethylenediamine) cobalt(Ⅲ) complex ion and the kinetics of nucleophilic substitution reaction between the complex and oxalate ions have been spectrophotometrically investigated in a aqueous solution. Measurements of the optical density at wave lengths 490, 510 amd 520 nm were carried out to determine the values of the equilibrium constants for the reactions: 〔Co(en)_2(H_2O)_2〕^3+ ⇔〔Co(en)_2(OH)(H_2O)〕^2+ + H^+ ; K_1 〔Co(en)_2(OH)(H_2O)〕^2+ ⇔〔Co(en)_2(OH)_2〕^+ + H^+ ; K_2 At 20℃ in sodium nitrate media of unit ionic strength the equilibrium constants for these reactions, K_1 and K_2 were 7.36×10 exp(-6) and 3.81×10 exp(-10) respectively. The anation reaction between complex and oxalate ions studied as a function of total oxalate ion concentrations, 〔Ox〕_Cau were carried out at a various pressure (1-1000 bar) and 60℃. By analysis of pseudo-first ordor rate constants observed as 〔Ox〕_T, it was found that the change of volume in the process of ion-pair formation, ΔV_5 is 8.3㎤/mole and that in the process of rate determining step, ΔV_a^≠=5.7㎤/mole. In addition, the rate law of anation reaction in a wide range of pH was described. And by the change of volume determined the mechanism of anation reaction was discussed.

초등학생의 1000m 달리기-걷기 평가방법에 관한 연구

박철호,박은경,고봉민,우상헌,안민호,차유림 東亞大學校附設스포츠科學硏究所 2002 스포츠科學硏究論文集 Vol.20 No.-

This research aims to develop a new evuluation method of endurance for elementary school students. The norm of the event of 1,000m running-walking was examined and reviewed. As a result, a new highly-valid norm for the present 1,000m running-walking was made. Among the 5th and 6th graders, 2,144 pupils were chosen. The subjects were given 1,000m running-walking and step test. The new norm led to the following results: 1. The frequency distribution of PEI according to Cajori's 5-stage evaluation method turned out to be normal for both 5th and 6th graders. In conclusion, this new norm of 1,000m running-walking is believed to provide more valid and credible scores for elementary school students. The 1,000m running-walking records and the PEI will be used as the basic data for foretelling one's endurance.

물-에탄올 혼합용매에서 Co(Ⅱ)-THPP(THPP: tetrakis-(ortho-hydroxy)phenylporphyrin) 착화합물 생성반응

朴裕哲,孫景千 慶北大學校 自然科學大學 1987 自然科學論文集 Vol.5 No.-

5, 10, 15, 20-tetrakis(ortho-hydroxy)phenylporphyrin(THPP) was synthesized by refluxation of (ortho-hydroxy)benzaldehyde with pyrrol in propionic acid. The protonation constants(K^H) of THPP were studied by spectrophotometric method at λ=540nm. From the results of this experiment, it showed that THPP exists in three ionic speces, THPPH_3^+, THPPH_2 and THPPH^- in pH=2∼11. The values of the protonation constants were THPPH^-+H^+??THPPH_2 ; K_2^H=3.421×10^5 THPPH_2+H^+??THPPH_3 ; K_3^H=1.887×10^9 The rate constants of the complex formation reaction of Co(Ⅱ) with THPP were studied in ionic strength of 0.1M NaCIO_4 at pH=3.5. The rate constants(sec^-1) were 1.440×10^-4, 1.380×10^-3, 5.400×10^3 and 1.220×10^-2 at T=25, 30, 35 and 40℃, respectively. The activation parameters, ΔH^≠ and ΔS^≠ were 53 kcal·mol^-1 and 102cal·mol^-1·deg^-1, respectively.

아세톤-물혼합용매에서 trans-[Co(en)_2Cl_2]^+ 및 trans-[Co(1,3-pn)_2Cl_2]^+ 이온의 가용매 분해 반응에 미치는 압력과 용매조성의 영향

朴裕哲,卞鍾轍,金京美,趙靈濟 慶北大學校 1984 論文集 Vol.38 No.-

The rates of solvolysis of trans-[Co(en)_2CL_2]^+ and trans- [Co(1,3-pn)_2CL_2]^+, in which en and 1,3-pn are ethylenediamine and 1,3-propylenediamine resepectively, have been investigated using conductometric and spectrophotometric methods at various pressures up to 2,000 bar in aceton-water mixture. The activation volumes obtained from the pressure effect on rate constants were small and positive values in both complexes of trans- [Co(en)_2Cl_2]^+ and trans- [Co(1,3-pn)_2CL_2]^+. These results are discussed in terms of dissociative mechanism (S_NI) for the solvolysis of both complexes. The importance of solvent composition on the reaction is further confirmed by application of a free energy cycle. It is concluded from the free energy cycle that the effect of solvation of transition state in the solvolysis of both complexes is more dominant than that of initial state. In addition to that, it is shown that the character of S_NI is further increased with increasing the content of acetone.

산성수욕액에서 cis-aquo-bis(ethylenediamine)cobalt(Ⅲ) 착이온의 평형 및 착이온과 oxalate 이온간의 치환반응에 미치는 압력영향

박유철,이동철 慶北大學校 物理化學硏究所 1984 硏究論文集 Vol.5 No.-

The chemical equilibrium of cis-aquo-bis(ethylenediamine)cobalt(Ⅲ) complex ion and the kinetics of nucleophilic substitution reaction between the complex and oxalate ions have been spectrophotometrically investigated in a aqueous solution. Measurements of the optical density at wave lengths 490, 510 and 520 nm were carried out to determine the values of the equilibrium constants for the reactions: 〔Co(en)_2(H_2O)_2〕^3+ ⇔ 〔Co(en)_2(OH)(H_2O)〕^2+ + H^+; K_1 〔Co(en)_2(OH)(H_2O)〕^2+ ⇔ 〔Co(en)_2(OH)_2〕^+ + H^+; K_2 At 20℃ and in sodium nitrate media of unit ionic strength the equilibrium constants for these reactions, K_1 and K_2 were 7.36×10 exp(-6) and 3.81×10 exp(-10) respectively. The anation reaction between complex and oxalate ions studied as a function of total oxalate ion concentrations, 〔Ox〕_T were carried out at a various pressure (1-1000bar) and 60℃. By analysis of pseudo-first ordor rate constants observed as 〔Ox〕_T, it was found that the change of volume in the precess ion-pair formation, ΔV_5 is 8.3㎤/mole and that in the precess of rate determining step, ΔV_a^≠=5.7㎤/mole. In addition, the rate law of anation reaction in a wide range of pH was described. And by the change of volume determined the mechanism of anation was discussed.