Immediate Vitrectomy for Acute Endophthalmitis in Patients with a Visual Acuity of Hand Motion or Better

Jaemin Kim(Jaemin Kim),Hyoung Seok Kim(Hyoung Seok Kim),Su Jin Yoo(Su Jin Yoo),Moon Jung Choi(Moon Jung Choi),Youngju Lew(Youngju Lew),Jong Woo Kim(Jong Woo Kim),Han Joo Cho(Han Joo Cho) 대한안과학회 2022 Korean Journal of Ophthalmology Vol.36 No.5

Purpose: To determine the efficacy of immediate pars plana vitrectomy as the primary treatment for acute endophthalmitis in patients with a visual acuity (VA) of hand motion (HM) or better. Methods: A total of 149 patients who were referred to a single center for acute endophthalmitis after cataract surgery over the 13-year study period were retrospectively analyzed. Only patients presenting with a VA of at least HM were included. Patients were initially treated with either primary vitrectomy or intravitreal antibiotic injection alone, and their visual outcomes and reintervention rates after initial treatment were compared. Results: There was no significant difference in the proportion of good (final VA ≥20 / 40) and poor (VA ≤ counting finger) visual outcomes between the groups. However, subgroup analysis of patients with a VA of HM (92 eyes) showed that the incidence of reintervention (14 of 72 eyes [19.4%] vs. 9 of 20 eyes [45.0%]) and poor visual outcomes (10 of 72 eyes [13.9%] vs. 8 of 20 eyes [40.0%]) were lower after prompt vitrectomy than after intravitreal antibiotic injection alone (p = 0.019 and p = 0.022, respectively). For those with a VA of at least counting finger, no significant difference was observed between the groups. Conclusions: For patients with endophthalmitis presenting with a VA of HM, performing a prompt vitrectomy reduced the incidence of reintervention and poor visual outcomes than the administration of intravitreal antibiotics alone. Our results suggest that primary vitrectomy for patients with endophthalmitis presenting with a VA of HM could be more beneficial than intravitreal antibiotic injection alone.

Feasibility evaluation of a neutron grating interferometer with an analyzer grating based on a structured scintillator

Kim, Youngju,Kim, Jongyul,Kim, Daeseung,Hussey, Daniel. S.,Lee, Seung Wook American Institute of Physics 2018 Review of scientific instruments Vol.89 No.3

Towards Sustainable Topsoil Management in South Korea

Youngju Kim,Kyoung Jae Lim,Sung-Chul Kim,Rog-young Kim,Jae E. Yang,Sang-il Hwang 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Characterization of Klebsiella pneumoniae Bacteriophages, KP1 and KP12 with Deep Learning-based Structure Prediction

Youngju KIM,Sang-Mok LEE,Linh Khanh NONG,Jaehyung KIM,Seung Bum KIM,Donghyuk KIM 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10

산림문화 향유 증진을 위한 전시 매체 및 공간 연출 분석

김영주 ( Kim Youngju ),김현주 ( Kim Hyunju ),오정은 ( Oh Jeongeun ),진혜영 ( Jin Hyeyoung ),김창준 ( Kim Changjun ) 한국공간디자인학회 2023 한국공간디자인학회논문집 Vol.18 No.8

(연구배경 및 목적) 박물관은 단순한 정보 제공을 넘어 경험의 가치를 높이는 복합문화공간으로 변화하고 있다. 이에 따라 다양한 문화를 다루는 전문박물관은 관람객이 자유롭게 전문적으로 문화를 향유 할 수 있도록 하는 효과적인 연출 매체의 적용이 필요하다. 국립수목원 산림박물관은 산림의 역사와 문화, 환경생태 전반에 관한 생물자원 서비스를 제공하고 있지만, 노후화된 시설과 정형화된 상설전시 환경으로 깊이 있는 정보 전달과 산림문화를 경험시키는 데에는 한계가 있다. 본 연구는 산림박물관을 찾는 관람객에게 산림과 관련된 지식을 흥미롭게 전달하기 위한 산림박물관의 전시 매체 연출의 방향성을 도출하는 데에 목적이 있다. (연구방법) 본 연구에서는 선행연구와 문헌 조사를 통해 주요 박물관들의 전시 매체의 유형과 연출 매체에 대해 조사 및 분류하였고, 산림박물관의 전시 현황과 소장품 및 전시주제에 대해 파악하였다. 이를 바탕으로 유사 전시 주제를 가진 국공립기관을 선정하여 주제 유형별 전시연출 특성과 매체를 파악하고, 분석자료를 토대로 산림박물관의 전시 매체 연출의 방향성을 도출하였다. (결과) 본 연구의 역사, 환경생태, 민속문화 분야별 대상기관 분석을 통해 도출된 결과는 다음과 같다. 첫째, 역사 분야에서는 다양한 미디어 기술과 융합된 동적 영상과 디오라마를 통해 특색있는 인터렉티브 영상 공간을 조성하여 관람객이 직관적으로 이해할 수 있는 환경을 구축해야 한다. 둘째, 환경생태 분야는 AR 증강현실 기술을 도입하여 접근성이 어려운 지역을 간접 체험하게 하거나 과학적인 연출을 통해 관람객들에게 환경생태에 대한 풍부한 경험과 깊은 이해를 촉진해야 한다. 셋째, 민속문화 분야는 기 소장품과 다양한 영상매체를 활용하여 관람객의 이해도를 높이고, 오감 체험을 통해 몰입환경을 향상해야 한다. (결론) 선정된 국공립 9개 기관을 분석하여 산림문화 향유 증진을 위한 산림박물관의 전시 매체 연출의 방향성을 도출하였다. 연구를 통해 역사, 환경생태, 민속문화 등 다양한 요소가 복합적으로 얽혀있는 산림문화를 관람객들에게 깊이 있게 전달하기 위해서 분야별 전시연출의 방향성을 도출하고 특성에 맞는 매체 및 연출이 수반되어야 함을 확인하였다. 향후 산림박물관이 산림문화 향유의 중심지로 탈바꿈할 수 있도록 전시 리모델링 시 전시연출 매체를 고려한 공간구성 계획이 함께 이루어져야 할 것이다. (Background and Purpose) Museum is transforming into a complex cultural space that elevates the value of the experience, beyond simply providing information. Accordingly, specialized museums showcase various cultures and must apply effective directing media that allow visitors to enjoy professional culture freely. The Korea National Arboretum Forest Museum provides biological resource services encompassing the history, culture, and environmental ecology of forests. However, aging facilities and a one-dimensional permanent exhibition environment pose challenges in delivering in-depth information and providing the experience of forest culture. This study aims to derive the direction of the Forest Museum’s exhibition media production to convey forest-related knowledge to visitors in an interesting way. (Method) This study investigated and classified the types of exhibition media and media in the spatial direction of major museums by examining prior research and conducting literature reviews, and identified the current status of exhibitions, collections, and exhibition topics in the Forest Museum. Based on this investigation, we selected national and public institutions with similar exhibition themes and identified the characteristics of exhibition directions and media by subject. This study also sets the path for the Forest Museum’s exhibition media based on the analysis. (Results) The results derived from the analysis of target institutions in the fields of history, environmental ecology, and folk culture were as follows: First, the field of history must create a unique interactive video space wherein dynamic images and dioramas are combined with various media technologies to enhance the audience’s intuitive understanding. Second, environmental and ecological fields should introduce augmented reality (AR) technology for audiences to indirectly experience inaccessible areas and gain a deep understanding of the environment and ecology. Third, the folk culture field should enhance the audience’s understanding by using current collections and various video media, and improve the immersive environment through experience with the five senses. (Conclusion) By analyzing nine selected national and public institutions, the direction of the Forest Museum’s exhibition media production to promote the enjoyment of forest culture was derived. This study confirms that exhibitions should be planned in different fields, with the relevant media and design adopted to convey forest culture in depth, wherein multiple factors―such as history, environmental and ecological factors, and folk culture―are complexly intertwined. For the Forest Museum to be transformed into a center for enjoying forest culture in the future, a space composition plan that considers exhibition production media should be implemented when remodeling exhibitions.

LTE-R 송수신기의 RAM 분석

김영주(Youngju Kim),김주엽(Juyeop Kim),신덕호(Ducko Shin),백종현(Jong-Hyen Baek),김용규(Yong-Kyu Kim) 한국통신학회 2016 한국통신학회 학술대회논문집 Vol.2016 No.1

Poster Session : PS 1585 ; Lung Cancer : Immunohistochemistry with EGFR Mutation-Specifi c Antibodies in Biopsy and Resection Specimens with Pulmonary Adenocarcinoma

( Chi Hong Kim ),( Seung Hoon Kim ),( Sonya Youngju Pak ),( Jin Young Yoo ),( Sung Kyoung Kim ),( Hoon Kyo Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Recently, mutation-specifi c antibodies have been developed for detecting epidermal growth factor receptor (EGFR) mutations by immunohistochemistry (IHC). This study was designed to determine the signifi cance of the type of specimen used for analysis (biopsy vs. resection), and to evaluate any correlation between mutation- specifi c antibodies and total EGFR protein (tEGFR) expressions. Methods: IHC using mutation-specifi c antibodies for E746-A750 deletion (DEL) and L858R point mutation (L858R) was performed in biopsies or tissue microarrays (TMA) of resected tumors from a total of 154 patients with lung adenocarcinoma. tEGFR was also investigated by IHC. Results were then compared with DNA sequencing data. Results: Molecular-based assays detected EGFR mutations in 62 (40.3%) patients, including 14 (9.1%) with DEL, and 31 (20.1%) with L858R. IHC with two mutation-speci fi c antibodies demonstrated a homogeneous staining pattern, and showed overall (biopsy/resection) sensitivity, specifi city, positive predictive value (PPV), and negative predictive value (NPV) of 75.6% (78.3%/72.7%), 94.5 % (90.9%/96.3%), 85% (78.3%/88.9%), and 90.4% (90.9%/89.7%), respectively. tEGFR showed low sensitivity, specifi city, PPV, and NPV, with no correlation with either DEL-specifi c or L858R-speci fi c antibodies. Conclusions: IHC using EGFR mutation-specific antibodies proved to be a reliable screening tool for identifying EGFR mutations in both biopsied and resected specimens with pulmonary adenocarcinoma, especially when the tumor cells in biopsy samples are not suffi cient for molecular biology techniques.

Thematic Poster : TP-45 ; Immunohistochemistry with EGFR Mutation-Specific Antibodies in Biopsy and Resection Specimens with Pulmonary Adenocarcinoma

( Chi Hong Kim ),( Seung Hoon Kim ),( Sonya Youngju Pak ),( Jin Young Yoo ),( Sung Kyoung Kim ),( Hoon Kyo Kim ) 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.0

Background: Recently, mutation-specific antibodies have been developed for detecting epidermal growth factor receptor (EGFR) mutations by immunohistochemistry (IHC). This study was designed to determine the significance of the type of specimen used for analysis (biopsy vs. resection), and to evaluate any correlation between mutation-specific antibodies and total EGFR protein (tEGFR) expressions. Methods: IHC using mutation-specific antibodies for E746-A750 deletion (DEL) and L858R point mutation (L858R) was performed in biopsies or tissue microarrays (TMA) of resected tumors from a total of 154 patients with lung adenocarcinoma. tEGFR was also investigated by IHC. Results were then compared with DNA sequencing data. Results: Molecular-based assays detected EGFR mutations in 62 (40.3%) patients, including 14 (9.1%) with DEL, and 31 (20.1%) with L858R. IHC with two mutation-specific antibodies demonstrated a homogeneous staining pattern, and showed overall (biopsy/resection) sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 75.6% (78.3%/72.7%), 94.5 % (90.9%/96.3%), 85% (78.3%/88.9%), and 90.4% (90.9%/89.7%), respectively. tEGFR showed low sensitivity, specificity, PPV, and NPV, with no correlation with either DEL-specific or L858R-specific antibodies. Conclusions: IHC using EGFR mutation-specific antibodies proved to be a reliable screening tool for identifying EGFR mutations in both biopsied and resected specimens with pulmonary adenocarcinoma, especially when the tumor cells in biopsy samples are not sufficient for molecular biology techniques.

맥진을 이용한 사상체질 판별 방법의 개선 및 의의

김재욱(Jaeuk Kim),김성훈(Sunghun Kim),이유정(Yujung Lee),전영주(Youngju Jeon),김근호(Keunho Kim),김종열(Jongyoel Kim) 한국한의학연구원 2009 한국한의학연구원논문집 Vol.15 No.2

Recently, there have been emerging research activities in classifying the Sasang constitution objectively by machine-based methods. The concordance rate of the classification by the pulse wave features was, however, only around 50% up to now. In this paper, we introduce a novel classification algorithm that can promote the accuracy substantially at the expense of the non-classifiable subgroup as a byproduct. For instance, with the pulse wave features alone, we show that female/male subject group in their 20s can be classified into the Sasang constitution group with the concordance rate of 68.4%/65.5% for a subgroup of 57/29(31%/15%) subjects out of 184/195, by leaving the other subjects as the non-classifiable group. Next, we show that the pulse diagnosis has been used only as a supportive tool in determining one's constitution, and consequently the accuracy of the concordance ratio by the pulse wave features alone cannot exceed a finite value, which we estimate to be about 60%.

SMART : High Performance Internet Server for High Definition Streaming Service

Yuhyeon Bak,Kapdong Kim,Youngju Lee,Songwoo Sok,Changsoo Kim,Hagyoung Kim,Myung-Joon Kim,Kyongsok Kim 보안공학연구지원센터 2007 International Journal of Smart Home Vol.1 No.1

In the current life, the Internet is playing a key role in transferring diverse information. As the performance of the Internet has been growing, transferred information has the form of multimedia streams such as video and audio. However, in current computing and internet environment, multimedia streaming service can't be accomplished smoothly due to the various factors such as internet bandwidth, computing power and so on. In this paper, we are proposing an efficient system, called SMART (Server for Multimedia Applications for Residence community) including hardware and software in terms of the design concept and system architecture for the multimedia streaming service. We also present the implementation result for the system.