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황석순,김권배,손수인,서영숙,김기식,김윤년 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.3
To evaluate the relationship between coronary artery disease(CAD) and the various levels of lipid and lipoproteins, we performed coronary angiography to the patient, who were suspected coronary artery disease from January 1988 to August 1989. And compared it with normal control group. The number of control group were 41(21 men, 20 women), and the patient group were 52(42 men, 10 women). The age was not differ between two groups. The results were as follows; 1. In CAD group, the plasma concentration of total lipid, triglyceride, total cholesterol, phosphlipid, and TC/HDL ratio were significantly higher than in control group. But, though, the concentration of HDL was lower in CAD group, had no significant difference between two groups. 2. The severity of CAD were well correlated with total lipid, cholesterol, LDL, trigylceride, phospholipid, TC/HDL, LDL/HDL levels. HDL level didnt's show significant correlation with the degree of CAD. We concluded that total lipid, cholesterol, trigylceride TC/LDL ratio were valuable markers of CAD in Korean, but futhur studies of lipoproteiins and other risk factors in the large population will be recommended.
Yoon, Hyung-Yoon,Kim, Seon-Kyu,Kim, Young-Won,Kang, Ho Won,Lee, Sang-Cheol,Ryu, Keun Ho,Shon, Ho Sun,Kim, Wun-Jae,Kim, Yong-June Mary Ann Liebert, Inc 2012 Journal of biomolecular screening Vol.17 No.7
<P>A total of 149 human prostate tissues obtained from our institute were assessed: 52 specimens of benign prostate hyperplasia (BPH) and 97 specimens of prostate cancer (PCa). The methylation status of the genes of Adenomatous polyposis coli (APC) and glutathione-S-transferase-P1 (GSTP1) was analyzed by quantitative pyrosequencing. A methylation score (M score) was calculated to capture the combined methylation level of both genes. The methylation level of each single gene and that of both genes combined was significantly higher in PCa specimens than in BPH (each p < 0.001). The value of APC methylation, GSTP1 methylation, and M score for predicting PCa was measured by the area under the receiver operating characteristic (ROC) curve and reached 0.954, 0.942, and 0.983, respectively. The sensitivity and specificity of the M score in discriminating between PCa and BPH reached 92.8% and 100.0%, respectively. The M score was positively associated with the serum prostate-specific antigen (PSA) level (p trend < 0.001). Our study demonstrates that the quantitative measurement of two methylation markers might drastically improve the ability to discriminate PCa from BPH.</P>
Magnetic Characteristics of Mn-Implanted GaN Nanorods Followed by Thermal Annealing
Yoon, Im Taek,Shon, Yoon,Kwon, Younghae,Park, Young S.,Park, Chang Soo,Kang, Tae Won Hindawi Limited 2012 Journal of nanomaterials Vol.2012 No.-
<P>We have investigated the magnetic and optical properties of dislocation-free vertical GaN nanorods with diameters of 150 nm grown on (111) Si substrates by radio-frequency plasma-assisted molecular-beam epitaxy followed by Mn ion implantation and annealing. The GaN nanorods are fully relaxed and have a very good crystal quality characterized by extremely strong and narrow photoluminescence excitonic lines near 3.47 eV. For GaMnN nanorods, it can be concluded that the ferromagnetic property of GaMnN nanorod with a Curie temperature over 300 K is associated with the formation of Mn4Si7magnetic phase which results from the effects of magnetic and structural disorder introduced by a random incorporation and inhomogeneous distribution of Mn atoms in the porous layer between the nanorods that form precipitates in the Si substrate before or during the annealing step amongst the GaN nanorods.</P>
임상의학의 ‘더러운 죽음’ 초월하기 : 마가렛 에드슨의 『위트』를 중심으로
손윤희 ( Shon¸ Yoon-hee ) 동국대학교 영어권문화연구소 2011 영어권문화연구 Vol.4 No.2
This study delves into transcending the dirty death from clinical medicine in the play Wit written by Margaret Edson. Philippe Aries explains death of the post-modern era as ‘dirty death’. All kinds of tube devices and equipments installed at the ICU (intensive care unit) in hospitals are ‘something essential for the contemporary medical technology’ to save patients in a comatose state, but at the same time, they are new kinds of ‘fear for death’. Under the pretext of curing diseases, medical doctors and instruments let the modern people face a tragic death in absolute helplessness and solitude. Such dirty death of clinical medicine in the post-modern era is well expressed in the play Wit. An English literature professor who specializes in the writings of John Donne, Vivian was diagnosed with late-stage ovarian cancer and started receiving chemical treatments accompanied with intense pain. she's faced with suffering through the human indignities of the total institutional hospital. Nevertheless she's struggle to resist medical politics on ill body, and tries to find a way to control her body, and pursues her autonomy. As a result, she transcends the dirty death from clinical medicine.
초등학교(初等學敎) 입지(立地)에 따른 건축적(建築的) 환경(環境) 조사연구(調査硏究)
손윤득(Shon, Yoon-Deuk),류종우(Lyou, Jong-Woo) 한국교육시설학회 2005 敎育施設 Vol.12 No.1
The purpose of this study is to suggest the reference materials in the selection of location of elementary school at the planning of building site development by analyzing the environment of architecture in the district of building site development. The method of investigation adapted the site investigation and drawing analysis of the elementary school, after collecting materials of the district of building site development within Busan city, under the object of investigation including 17 elementary schools within 15 districts of building site development and the object of investigation.
조윤영 Yoon Young Cho,Ho Sang Shon,Hyun Dae Yoon 대한내과학회 2005 The Korean Journal of Internal Medicine Vol.20 No.4
Relapse and exacerbation of Graves` disease during pregnancy is rare, and thionamide induced agranulocytosis is an uncommon side effect. We report a case of a pregnant woman in her 24th week of gestation that experienced a relapse of Graves` disease that w
Hwang Yoon Hyuk,Shon YoungSuk,Yoon Young Joon,염종훈 대한마취통증의학회 2022 Korean Journal of Anesthesiology Vol.75 No.6
Background: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a type of autoimmune encephalitis that causes characteristic symptoms through the formation of antibodies against NMDA receptors. If ovarian teratomas are detected, surgical removal under general anesthesia is often considered. Many general anesthetic agents inhibit NMDA receptors. As such, anesthetic agents may have unexpected effects on disease progression. For anesthesiologists, providing general anesthesia for these patients is challenging and there are few studies on which anesthetic is most appropriate. Case: Two female patients were diagnosed with anti-NMDA receptor encephalitis and ovarian teratomas. Successful teratoma resection was performed under general anesthesia using remimazolam and remifentanil. After the surgery, one patient showed some improvement but died a month later. The other patient progressively improved over time. Conclusions: Remimazolam and remifentanil are useful general anesthetic agents for patients with anti-NMDA receptor encephalitis. Further studies are warranted.