Effects of Indium Composition Ratio on Electrical Stability of Top-gate Self-aligned Coplanar IGZO TFTs under Self-heating Stress Conditions

Yeong-Gil Kim,Chae-Eun Oh,Ye-Lim Han,Dong-Ho Lee,Joon-Young Lee,Kyoung-Seok Son,Jun Hyung Lim,Ick-Joon Park,Sang-Hun Song,Hyuck-In Kwon 대한전자공학회 2024 Journal of semiconductor technology and science Vol.24 No.4

We demonstrated that the indium composition ratio in the channel layer significantly affects the electrical stability of top-gate self-aligned (TG SA) coplanar structure indium-gallium-zinc oxide (IGZO) thin-film transistors (TFTs) under self-heating stress (SHS) conditions. The transfer curves of the In-poor IGZO TFT continuously shifted in the positive direction with extended stress time, without a significant change in the subthreshold swing (SS) and field-effect mobility (μFE) values during SHS application. In contrast, the transfer curve of the In-rich IGZO TFT shifted in the negative direction until the SHS time reaches 1200 s, after which it shifted in the positive direction with extended stress time. Besides, SS and μFE values continuously increased as the SHS time increased in the In-rich IGZO TFTs. The unusual behavior of the TG SA coplanar In-rich IGZO TFT during SHS is mainly attributed to the more pronounced diffusion of hydrogen (H) atoms from the n+-IGZO source/drain extension region to the IGZO channel region in the In-rich IGZO than in the In-poor IGZO. The H atoms diffused into the IGZO channel layer act as either shallow donors or deep acceptors, depending on their concentration and environmental conditions, thus causing the abnormal behavior of IGZO TFTs during SHS.

Effect of Long-term Administration of Jeju barley (Hordeum vulgare) Extract on Weight Management in In-vivo Animal Model

Su-Young Lee,Ji-Yoon Hong,Tae Yang Kim,Jin-A Yu,Gi Jung Kim,Ye Lim Jang,Tessema Haimanot Miticu,Jung Bae Oh,Young-In Kwon 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

In this study, the effect of long-term intake of Jeju barley extract (JBE) on the anti-obesity was evaluated using diet-induced obesity C57BL/6 mouse model. The animal experiment was conducted for 8 weeks, and a total of 20 mice were divided into 4 groups: a normal diet group (ND), high-fat diet group (HFD), barley 0.3 g/kg group (BL) and barley 0.5 g/kg group (BH). The JBE administration group was fed a high-fat diet and the sample was orally administered twice a day. As a result of measuring the change in body weight every other day, it was confirmed that the BL and BH group showed less weight gain than the HFD group. After sacrifice, various adipose tissue weights, lipid levels {total cholesterol (TC), triglycerides (TG), HDL-Cholesterol (HDL-C), LDL-Cholesterol (LDL-C)}, adiponectin, leptin, TNF-α, IL-6 and insulin were measured. TC, TG and LDL-C levels were significantly lower in the BL group than in the HFD group. It was also confirmed that the leptin level was significantly lower than that of the HFD group. These results indicate that proper intake of JBE may reduce weight gain and improve obesity-related indicators such as adiponectin, leptin, TC, TG and HDL-C levels.

대기 중 오염물질의 시료채취시 관측오차 저감방법에 대한 연구 : 6구형 매니폴더를 장착한 MFC system의 개발과 평가 Development and Assessment of a Six-port Manifold MFC System

김기현,오상인,최여진,김민영,최규훈 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.4

In order to develop a confident sampling technique, we designed and constructed a 6-port manifold MFC sampling system for collecting gaseous pollutants in air. Using this instrumentation, we tested the performance criteria of MFC system in terms of: (1) flow rate; (2) MFC-to-MFC variability: (3) tube-to-tube variability: and (4) time. It was interesting to find that the later two factors did not show any significant variations, while the former two show substantially large variations. However, as most of those variabilities are consistent enough to form systematic patterns, we were able to explain the occurrence patterns of all those MFC biases in terms of those tour major variables. The overall results of our experiment suggest that one needs to use correction factor for each MFC unit under a given flow rate to maintain optimal accuracy and precision for sampling of those pollutants.

CORBA를 이용한 네트워크 모니터링 시스템의 설계 및 구현

오인환,김지예,엄영익 成均館大學校 科學技術硏究所 1999 論文集 Vol.50 No.1

Network management that has become an important issue for the rapidly growing Internet is actively studied for efficient channel management, particularly for the overloaded ones. For this management, packet monitoring techniques and analysis methodologies based on the monitored packets are fundamental components. In this paper, we designed and implemented network monitoring system that provides users the network status and performance information from the network packets over the channel. The system is implemented in the CORBA environment and written in the Java language in order to provide independence of heterogeneous platforms as well as scalability to various development environments. In particular, this system provides users transparency and convenience for monitoring the Internet because it is implemented in the portable language Java.

연속측정방법을 이용한 도심권 대기질 내 저농도 황화합물의 관측에 대한 연구

최여진,김기현,오상인,손장호 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.2

In this study, the concentrations of major reduced sulfur compounds (H₂S, CH₃SH, DMS, and DMDS) were determined from ambient air in a monitoring station located in the mid-eastern area of Seoul. Measurements of sulfur species were conducted by the combination of on-line air sampling, thermal desorption, and capillary GC/PFPD analysis. A total number of 143 hourly samples were collected in the two time periods set between June and July 2003. The mean concentrations of four sulfur species measured in the whole study period were found on the order: DMS (535±183H) > H₂S (47±10) > DMDS (35±22) > CH₃SH (6.19±29.4 pptv). The results of this study show that the concentrations of DMS at the study area are generally higher than those reported previously in the oceanic environments, while those of other sulfur species are not easy to compare with due to the lack of data. The H₂S concentrations were generally higher during the daytime than the nighttime, whereas those of others generally exhibited a reversed diurnal pattern. The overall results of our study suggest that the distribution of major reduced S compounds should be controlled by diverse processes in the urban area.

방향족 휘발성 유기화합물의 겨울철 연속 관측 연구

최여진,오상인,김기현 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.5

In the present work, the distribution characteristics of ambient volatile organic compounds (VOCs) were investigated at high temporal resolution from a monitoring station located in a mid-eastern area of Seoul. A total number of 587 samples were collected during December 2002 to January 2003. The measurements of VOC were conducted by a combination of on-line air sampling and thermal desorption unit (TDU) coupled with capillary GC/FID analysis. A total of five aromatic compounds (BTEX: benzene, toluene, ethyIbenzene, m, p-xylene, and o-xylene) were, measured routinely at hourly intervals during the whole study period. The mean concentrations of BTEX measured in our study period were found in the order: toluene (8.99±5.38ppb)>benzene(0.92±0.52ppb)>m, p-xylene (0.51±0.34ppb)>o-xylene(0.48±0.35ppb)>ethyl benzene (0.43±0.32ppb). The BTEX concentrations were generally higher during the daytime than the nighttime, exhibiting certain patterns on a weekly basis. Results of our analysis indicate that the unusually high concentrations of toluene, while showing good correlations with other VOCs, can be a good indicator of air pollution in the study area.

Clinical Significance of F-18 FP-CIT Dual Time Point PET Imaging in Idiopathic Parkinson's Disease

Oh, Jin-Kyoung,Yoo, Ik-Dong,Seo, Ye-Young,Chung, Yong-An,Yoo, Ie-Ryung,Kim, Sung-Hoon,Song, In-Uk The Korea Society of Nuclear Medicine 2011 핵의학 분자영상 Vol.45 No.4

Purpose The purpose of this study was to investigate the diagnostic value of dual time point F-18 FP-CIT PET imaging in idiopathic Parkinson's disease (PD). Materials and Methods Twenty-four patients with PD (mean age 69.6) and 18 healthy people (mean age 70.26) underwent two sequential PET/CT scans (dual time point imaging) at 90 and 210 min after F-18 FPCIT injection. Tracer activity of region of interest was measured in the caudate, putamen and a reference region in the brain from both time points. The outcome parameter was the striatooccipital ratio (SOR). Normal SOR values were obtained in the control group. The percent change in tracer activity between 90- and 210- min images was calculated. The SOR values and the percent change in tracer activity were compared between the patients and healthy control group. Results The SOR values for the caudate, anterior and posterior putamen at both 90- and 210-min images were significantly reduced in the patients with PD. The lowest P value was obtained for the anterior and posterior putamen (p<0.001) at both time points. There were significant differences of the percent change in tracer activity for the anterior and posterior putamen in the two groups (p=0.01). Conclusions F-18 FP-CIT PET scans at 90 and 210 min after injection are both able to diagnose PD. Therefore, the 90-min image by itself is sufficient for diagnosing PD.

Serum Alanine Aminotransferase Level and Mortality from Liver Disease in Patients with Chronic Hepatitis B: Prospective Cohort Study

( Jae-jun Shim ),( Jin Sun Park ),( Ye-rin Lee ),( In Hwan Oh ),( Ji Sung Lee ),( Byung-ho Kim ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: In patients with chronic hepatitis B (CHB), evidence of liver damage, which appears as elevation of serum alanine aminotransferase (ALT) is required before initiation of antiviral therapy. However, it is not known which ALT level is associated with liver-related mortality. Methods: We used a Health Examination Cohort of National Health Insurance Service (NHIS) in Korea. The cohort included approximately 0.5 million individuals (40 to 79 years old) who received biennial health examination between January 01, 2002, and December 31, 2007. During the period, CHB group was selected using disease diagnosis code (B180 or B181). Mortality from liver diseases (K71~K79) including liver cancer (C22) was investigated according to baseline serum ALT levels. Results: Total 12,486 individuals with CHB (male 6,424 and female 6,062) were enrolled. During 111,844 person-years (mean 9.0 years of follow-up), 248 were died from liver related diseases (213 of them from liver cancer). Elevated ALT level was positively correlated with liver-related mortality in both sexes. The liver-related mortality in men was 0.14%, 0.17%, 0.24%, 0.57%, 0.63%, and 0.85% in serum ALT < 19, 20-29, 30-39, 40-49, 50-79, and ≥ 80 U/L, respectively. The mortality in women was 0.03%, 0.09%, 0.12%, 0.63%, 0.65%, and 0.32% in the same interval, respectively. In a multivariate Cox proportional hazards model adjusting age, body mass index, hypertension, serum triglyceride level, gamma-glutamyl transpeptidase, and total cholesterol, serum ALT level was the independent predictor of liver-related mortality. The best cut-off level of serum ALT to predict liver-related death was > 34 IU/L in men and > 30 in women. Conclusions: Among patients with CHB older than 40 years, liver-related mortality significantly increase even in low range of serum ALT level. Threshold of ALT level for initiation to antiviral therapy should be optimized to reduce the liver-related mortality in CHB patients.

유아 대상 채소와 과일, 유제품의 충분한 섭취를 위한 영양교육 실시 및 효과 평가

오수민(Su Min Oh),유예리(Ye Lee Yu),최혜인(Hye In Choi),김경원(Kyung Won Kim) 대한지역사회영양학회 2012 대한지역사회영양학회지 Vol.17 No.5

The purpose of the study was to implement and evaluate a nutrition education program for preschool children. Applying the PRECEDE-PROCEED model, the nutrition education program was developed and focused on changing beliefs, increasing nutrition knowledge and consumption of vegetables & fruits (V/F) and dairy foods. Subjects were children attending a childcare center in Seoulwho were grouped into education (n = 33) and control group (n = 32). Education group received four sessions of nutrition education during 2011 fall. Both groups completed the questionnaire at pretest and posttest, measuring nutrition knowledge, beliefs, and preferences of V/F and eating behaviors. Compared to control group, education group made significant gains in total score of nutrition knowledge after the education (p < 0.05). In addition, the pretest-posttest changes in total score of beliefs regarding V/F consumption and eating behaviors were higher in the education group than in the control group (p < 0.05). Two groups were significantly different in the pretest-posttest changes in specific beliefs regarding the benefits of V/F consumption and some eating behavior. However, there were no changes in the preferences of vegetables or fruits between the two groups after the education. The consumption of V/F and dairy foods was not significantly different after the education. This study revealed that nutrition education for preschoolers was effective in improving nutrition knowledge and perceived benefits regarding V/F consumption and specific eating behavior. This study suggested that more intensive education is needed to induce changes in eating behaviors. This program can be used in nutrition education of children at the childcare centers or kindergartens.

α-Lipoic Acid Prevents Endothelial Dysfunction in Obese Rats via Activation of AMP-Activated Protein Kinase

Lee, Woo Je,Lee, In Kyu,Kim, Hyoun Sik,Kim, Yun Mi,Koh, Eun Hee,Won, Jong Chul,Han, Sung Min,Kim, Min-Seon,Jo, Inho,Oh, Goo Taeg,Park, In-Sun,Youn, Jang Hyun,Park, Seong-Wook,Lee, Ki-Up,Park, Joong-Ye Ovid Technologies Wolters Kluwer -American Heart A 2005 Arteriosclerosis, thrombosis, and vascular biology Vol.25 No.12

<P>OBJECTIVE: Lipid accumulation in vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis in obese subjects. We showed previously that alpha-lipoic acid (ALA) activates AMP-activated protein kinase (AMPK) and reduces lipid accumulation in skeletal muscle of obese rats. Here, we investigated whether ALA improves endothelial dysfunction in obese rats by activating AMPK in endothelial cells. METHODS AND RESULTS: Endothelium-dependent vascular relaxation was impaired, and the number of apoptotic endothelial cells was higher in the aorta of obese rats compared with control rats. In addition, triglyceride and lipid peroxide levels were higher, and NO synthesis was lower. Administration of ALA improved all of these abnormalities. AMPK activity was lower in aortic endothelium of obese rats, and ALA normalized it. Incubation of human aortic endothelial cells with ALA activated AMPK and protected cells from linoleic acid-induced apoptosis. Dominant-negative AMPK inhibited the antiapoptotic effects of ALA. CONCLUSIONS: Reduced AMPK activation may play an important role in the genesis of endothelial dysfunction in obese rats. ALA improves vascular dysfunction by normalizing lipid metabolism and activating AMPK in endothelial cells.</P>