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사무직 근로자의 수면의 질 및 직무스트레스와 우울과의 관련성
강미나,강수영,권수정,김현주,배재원,이보연,이예진,임의롬,정다영,조한솔 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47
Purpose: The purpose of this study was to understand the degree of depression, sleep quality, job stress and their association among office workers. Method: A self-administered questionnaire was distributed to 147 workers employed in 5 big enterprises, and 5 small and medium enterprises from October 21 to November 21, 2012. The questionnaires included socio-demographic and health-related characteristics, job-related characteristics, sleep quality, job stress (KOSS) and depression (CES-D). Result: Among all subjects, 23.1% was in the depression group (21 points and over in the CES-D score). Depressive level was positively correlated with job stress and quality of sleep. The adjusted odd ratio for the effects of sleep quality and job stress on depression significantly increased in the depression group compared to that of the normal group. Multiple regression analysis revealed that the following factors of influence had combined explanatory powers on depression: BMI, life satisfaction, quality of sleep, and job stress. Conclusion: The study revealed that complicated influences were exerted on the level of depression by variable factors, as well as socio-demographic characteristics, health-related characteristics, quality of sleep, and job stress. Specifically, the level of depression was influenced by the quality of sleep and job stress.
Kang, Ho Won,Seo, Sung Pil,Byun, Young Joon,Piao, Xuan-Mei,Kim, Ye-Hwan,Jeong, Pildu,Ha, Yun-Sok,Kim, Won Tae,Kim, Yong-June,Lee, Sang-Cheol,Moon, Sung-Kwon,Choi, Yung-Hyun,Yun, Seok-Joong,Kim, Wun-Ja Elsevier 2018 Clinical genitourinary cancer Vol.16 No.4
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Pathologic T1 high-grade (pT1HG) bladder cancer (BC) is characterized by a high progression rate and constitutes an important clinical challenge; however, there is no consensus on the prediction of progression in pT1HG BC. The purpose of this study was to validate previously published molecular progression risk score (MoPRS) for predicting muscle-invasive disease in pT1HG BC.</P> <P><B>Materials and Methods</B></P> <P>The expression of an 8-gene progression-related classifier identified from microarray data was analyzed by real-time PCR, and the MoPRS was calculated in 121 newly recruited patients with pT1HG BC. Progression was defined as muscle invasion or metastasis.</P> <P><B>Results</B></P> <P>Overall, the disease of 28 patients (23.1%) progressed to muscle-invasive BC during the median follow-up of 63.7 (interquartile range, 17.6-96.4) months. The MoPRS was significantly higher in 1973 World Health Organization grade 3 than grade 2 tumors (<I>P</I> = .004). Early development of invasive BC was more prevalent in the highest quartile MoPRS group than in the lowest to 75th percentile MoPRS groups according to Kaplan-Meier analysis. Multivariate Cox regression analysis revealed that the MoPRS was an independent predictor of invasive BC, either as a continuous variable (hazard ratio, 1.624; 95% confidence interval, 1.266-2.082; <I>P</I> < .001) or as a categorical variable (hazard ratio, 3.089; 95% confidence interval, 1.335-7.150; <I>P</I> = .008).</P> <P><B>Conclusion</B></P> <P>The MoPRS was an independent prognostic factor for identifying patients at high risk of invasive BC in patients with pT1HG BC. This scale may help identify patients who could benefit from more aggressive therapeutic intervention such as early cystectomy.</P>
Copper-Catalyzed TEMPO Addition to Propargyl Alcohols for the Synthesis of Vinylic Alkoxyamines
Kang, Ye-Won,Choi, Yoon-Jeong,Jang, Hye-Young American Chemical Society 2014 ORGANIC LETTERS Vol.16 No.18
<P>A variety of vinylic alkoxyamines derived from propargyl alcohols and 2,2,6,6-tetramethylpiperidine <I>N</I>-oxyl (TEMPO) were synthesized in good yields under copper-catalyzed aerobic conditions. A reaction mechanism was proposed, involving the isomerization of propargyl radicals to allenic radicals, and related mechanistic studies were performed. The kinetic isotope effect on the propargyl C–H bond cleavage (α-deprotonation) reaction was observed (<I>k</I><SUB>H</SUB>/<I>k</I><SUB>D</SUB> = 3.76).</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/orlef7/2014/orlef7.2014.16.issue-18/ol502341f/production/images/medium/ol-2014-02341f_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ol502341f'>ACS Electronic Supporting Info</A></P>
Ye Seong Kang,Seong Heon Kim,Jeong Gyun Kang,Tapash Kumar Sarkar,Young Seok Kwon,Sae Rom Jun,Won Jun Kim,Chan Seok Ryu 경상대학교 농업생명과학연구원 2017 농업생명과학연구 Vol.51 No.4
It is necessary to monitor growth status of the crops due to continuous change of climate causing insecurity in crop cultivation. Low altitude remote sensing(LARS) system is utilized to accurately monitor the growth status of the crops. In this study, models for monitoring fresh weight(FW), one of the major growth factors of Chinese cabbage, were developed with structural indices and simple ratio calculated from bands in remotely sensed canopies by NIR, RE(imaging sensor A) and multispec-4c sensors(imaging sensor B) equipped with fixed-wing UAV depending on vegetation stages of normal planting(NP) and delayed planting(DP) Chinese cabbages. In results of imaging sensor A, the estimation models using structural indices and simple ratio were divided into NP and DP due to different attribute of reflectance in canopies with changed environment condition depending on different planting dates. The estimation models using simple ratio calculated by red edge and visible bands of NP showed better performance than other models, but RMSE was high. The models using simple ratio calculated by same bands of DP were feasible to accurately estimate FW(R2 of more than 0.946 with RMSE of less than 169.5 g). In results of imaging sensor B, the estimation models using structural indices and simple ratio on DP were divided into low to intermediate FW and intermediate to high FW. As a result, estimation models of all structural indices and simple ratio in low to intermediate FW bands were advisable to estimate FW(R2 of more than 0.860 with RMSE of less than 104.7 g). Estimation models of those calculated by red edge and visible bands in intermediate to high FW were only possible to accurately estimate FW(R2 of more than 0.532 with RMSE of less than 400.7 g).
Kang Ye-Won,Sun Tai hui,Kim Ga-Yeong,Jung Ho-Young,Kim Hyun-Jin,Lee Seulki,Park Yu Rang,Tu Jaiden,Lee Jae-Hon,Choi Kwang-Yeon,Cho Chul-Hyun 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.7
In this study, the Search Your Mind (S.Y.M., 心) project aimed to collect prospective digital phenotypic data centered on mood and anxiety symptoms across psychiatric disorders through a smartphone application (app) platform while using both centralized and decentralized research designs: the centralized research design is a hybrid of a general prospective observational study and a digital platform-based study, and it includes face-to-face research such as informed written consent, clinical evaluation, and blood sampling. It also includes digital phenotypic assessment through an application-based platform using wearable devices. Meanwhile, the decentralized research design is a non-face-to-face study in which anonymous participants agree to electronic informed consent forms on the app. It also exclusively uses an application-based platform to acquire individualized digital phenotypic data. We expect to collect clinical, biological, and digital phenotypic data centered on mood and anxiety symptoms, and we propose a possible model of centralized and decentralized research design.
고정익 무인기로 획득한 다중분광 영상을 이용한 무의 생육 추정
강예성 ( Ye Seong Kang ),김성헌 ( Seong Heon Kim ),강정균 ( Jeong Gyun Kang ),전새롬 ( Sae Rom Jun ),김원준 ( Won Jun Kim ),타파스쿠마 ( Tapash Kumar Sarkar ),유찬석 ( Chan Seok Ryu ) 한국농업기계학회 2016 한국농업기계학회 학술발표논문집 Vol.21 No.2
본 연구는 고정익 무인기(eBee, Sensefly, Swiss)에 탑재된 다중분광센서(Multispec4C, Airinov, Switzerland)로 취득한 무 포장의 영상(공간분해능:6cm)을 이용하여 산출한 식생지수로 잎 생체중과 수확량을 추정하기 위해 수행되었다. 다중분광센서의 Green, Red, Red edge, NIR 파장영역을 이용하여 무의 캐노피를 생육단계별로 촬영하였고 5개 무의 잎에 평균 반사값으로 NDVI와 개체영역을 지정하면서 생길 수 있는 토양의 영향을 최소화하기 SAVI 및 OSAVI를 각각 산출하였다. 산출된 식생지수(NDVI, SAVI, OSAVI)와 측정한 생육 데이터를 이용하여 상관 및 회귀분석을 하였다. 무의 수확량 추정모델을 분석한 결과 무의 생육 기간이 길어짐(50일 이후)에 따라 NDVI, SAVI 및 OSAVI값이 포화되는 경향이 나타나 모델의 정확도 및 정밀도가 낮아졌다. 따라서 생육기간이 50일 이하인 데이터를 이용하여 다시 분석한 결과 NDVI를 이용한 모델에서는 정확도와 정밀도가 높아졌으나 SAVI 및 OSAVI의 결과보다는 낮았다. SAVI를 이용한 추정모델은 정확도(R2)가 0.718, 정밀도(RMSE)가 162.4g로 나타났고, OSAVI를 이용한 추정모델은 정확도(R2)가 0.653, 정밀도(RMSE)가 180.1g로 나타났다. 무 잎의 생체중은 무의 수확량과 높은 상관성 r=0.997을 보였기 때문에 무의 수확량 추정모델과 비슷한 경향을 보였다. 결과적으로 무의 수확량과 무 잎의 생체중을 추정하기 위한 모델에서 생육기간에 따라 큰 성능차이를 보였고 그 중 식생지수 SAVI를 이용한 모델이 다른 식생지수를 이용한 모델보다 개체영역별 무의 생육을 추정하기에 가장 좋은 모델의 결과를 보였다.