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      • KCI등재

        \boldmath$(\mathcal{V},\mathcal{W},\mathcal{Y},\mathcal{X})$-Gorenstein complexes

        Yanjie Li,Renyu Zhao 대한수학회 2024 대한수학회지 Vol.61 No.3

        Let $\mathcal{V}$, $\mathcal{W}$, $\mathcal{Y}$, $\mathcal{X}$ be four classes of left $R$-modules. The notion of $(\mathcal{V, W, Y, X})$-Gorenstein $R$-complexes is introduced, and it is shown that under certain mild technical assumptions on $\mathcal{V}$, $\mathcal{W}$, $\mathcal{Y}$, $\mathcal{X}$, an $R$-complex $\bm{M}$ is $(\mathcal{V, W, Y, X})$-Gorenstein if and only if the module in each degree of $\bm{M}$ is $(\mathcal{V, W, Y, X})$-Gorenstein and the total Hom complexs Hom$_R(\bm{Y},\bm{M})$, Hom$_R(\bm{M},\bm{X})$ are exact for any $\bm{Y}\in\widetilde{\mathcal{Y}}$ and any $\bm{X}\in\widetilde{\mathcal{X}}$. Many known results are recovered, and some new cases are also naturally generated.

      • KCI등재

        Setosphapyrone C and D accelerate macrophages cholesterol effl ux by promoting LXRa/ABCA1 pathway

        Ting Li,Jiayu Yin,Yubin Ji,Ping Lin,Yanjie Li,Zixun Yang,Shumei Hu,Jin Wang,Baihui Zhang,Saloni Koshti,Junfeng Wang,Chenfeng Ji,Shoudong Guo 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.8

        LXRα agonists have attracted signifi cant attentiondue to their potential biological activities on promotingcholesterol effl ux. This study was designed to investigatewhether setosphapyrone C and D have potential lipid-loweringcapacity and the underlying mechanisms in vitro. Ourdata showed that setosphapyrone C and D had weak cytotoxicitycompared to the liver X receptor α (LXRα) agonistT0901317. In RAW 264.7 macrophages, setosphapyroneC and D signifi cantly enhanced [ 3 H]-cholesterol effl ux by~ 21.3% and 32.4%, respectively; furthermore, setosphapyroneC and D enhanced the protein levels of ATP-bindingcassette transporter (ABC) A1 and LXRα by 58% and 69%,and 60% and 70% (8 μM), respectively; however, they had noeff ect on the protein levels of ABCG1 and scavenger receptorB type 1; additionally, they had minor eff ect on the mRNAexpression of lipogenic genes. Of note, setosphapyrone C and D signifi cantly enhanced LXRα/ABCA1pathway inmice primary macrophages. In BRL cells, setosphapyroneC and D signifi cantly improved the protein levels of ABCA1and ABCG1; setosphapyrone D signifi cantly enhanced theprotein expression of low-density lipoprotein. Collectively,setosphapyrone C and D with weak cytotoxicity exhibitedeff ective lipid-lowering eff ect via enhancing LXRα/ABCpathways. Setosphapyrones possess potential applicationfor the treatment of hyperlipidemic diseases.

      • Multiple-shot People Re-identify based on Feature Selection with Sparsity

        Dongping Zhang,Yanjie Li,Jiao Xu,Ye Shen 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.1

        In a video surveillance network, it is always required to track and recognize people when they move through the environment. This paper presents a novel re-identification method for multiple-people using feature selection with sparsity. By using the multiple-shot approach, each of appearance models is created in this method. The human body is divided into five parts form which the features of color, height, gradient were extracted respectively. Our appearance model is represented by linear regression method. Experimental results show that our appearance model is robust and attain a high precision rate and processing performance.

      • KCI등재

        YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis

        Su Wei,Guo Yingying,Wang Qianqian,Ma Lu,Zhang Qing,Zhang Yuhan,Geng Yiding,Jin Tongzhu,Guo Jiayu,Yang Ruoxuan,Niu Zhihui,Ren Lingxue,Wang Yanjie,Ning Zhiwei,Li Wenyue,He Wenxin,Sun Jian,Li Tianyu,Li Z 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-

        The senescence of alveolar type II (AT2) cells impedes self-repair of the lung epithelium and contributes to lung injury in the setting of idiopathic pulmonary fibrosis (IPF). Yes-associated protein 1 (YAP1) is essential for cell growth and organ development; however, the role of YAP1 in AT2 cells during pulmonary fibrosis is still unclear. YAP1 expression was found to be downregulated in the AT2 cells of PF patients. Deletion of YAP1 in AT2 cells resulted in lung injury, exacerbated extracellular matrix (ECM) deposition, and worsened lung function. In contrast, overexpression of YAP1 in AT2 cells promoted alveolar regeneration, mitigated pulmonary fibrosis, and improved lung function. In addition, overexpression of YAP1 alleviated bleomycin (BLM) -induced senescence of alveolar epithelial cells both in vivo and in vitro. Moreover, YAP1 promoted the expression of peroxiredoxin 3 (Prdx3) by directly interacting with TEAD1. Forced expression of Prdx3 inhibited senescence and improved mitochondrial dysfunction in BLM-treated MLE-12 cells, whereas depletion of Prdx3 partially abrogated the protective effect of YAP1. Furthermore, overexpression of Prdx3 facilitated self-repair of the injured lung and reduced ECM deposition, while silencing Prdx3 attenuated the antifibrotic effect of YAP1. In conclusion, this study demonstrated that YAP1 alleviates lung injury and pulmonary fibrosis by regulating Prdx3 expression to improve mitochondrial dysfunction and block senescence in AT2 cells, revealing a potential novel therapeutic strategy for pulmonary fibrosis.

      • SCOPUSKCI등재

        Face Recognition Based on the Combination of Enhanced Local Texture Feature and DBN under Complex Illumination Conditions

        Li, Chen,Zhao, Shuai,Xiao, Ke,Wang, Yanjie Korea Information Processing Society 2018 Journal of information processing systems Vol.14 No.1

        To combat the adverse impact imposed by illumination variation in the face recognition process, an effective and feasible algorithm is proposed in this paper. Firstly, an enhanced local texture feature is presented by applying the central symmetric encode principle on the fused component images acquired from the wavelet decomposition. Then the proposed local texture features are combined with Deep Belief Network (DBN) to gain robust deep features of face images under severe illumination conditions. Abundant experiments with different test schemes are conducted on both CMU-PIE and Extended Yale-B databases which contain face images under various illumination condition. Compared with the DBN, LBP combined with DBN and CSLBP combined with DBN, our proposed method achieves the most satisfying recognition rate regardless of the database used, the test scheme adopted or the illumination condition encountered, especially for the face recognition under severe illumination variation.

      • KCI등재

        Long supplementary light duration under same daily light integral provided by white plus blue light-emitting diodes improves quality of greenhouse-grown tomato seedlings

        Li Xin,Wang Chunling,Liu Jiawei,Guo Yu,Cheng Fei,Yang Yanjie,Yan Zhengnan 한국원예학회 2023 Horticulture, Environment, and Biotechnology Vol.64 No.6

        Optimizing light conditions is critical for plant growth and seedling production in greenhouse, especially in seasons when the sunlight is insuffi cient. In the present study, tomato ( Solanum Lycopersicum cv. Fenbeibei) seedlings were grown at two levels of supplementary light duration of 6 h·d − 1 (short) (07:00–10:00 and 15:00–18:00) or 12 h·d − 1 (long) (04:00–10:00 and 15:00–21:00) provided by white light-emitting diodes (LEDs, white long and white short, WL and WS) or combinations of white and blue LEDs (white & blue long and white & blue short, WBL and WBS) with same supplementary daily light integral (at 5.5 mol m − 2 d − 1 ) after sowing, and tomato seedlings grown under sunlight only were set as the control. The per centages of light intensity provided by white and blue LEDs under the WB treatments were 85% and 15%, respectively. The results indicated that tomato seedlings grown under WBL treatment exhibited the lowest plant height and shortest hypocotyl length, which was decreased by 34.6% and 41.8%, respectively, compared with the control. The chlorophyll a, chlorophyll b, and total chlorophyll contents of tomato seedlings grown under WBL were signifi cant higher than those under other treat ments. The root fresh weight, root dry weight, and the stem fi rmness of the greenhouse-grown tomato seedlings under WBL were increased by 21.5%, 41.2%, and 38.6%, compared with those grown under WBS, respectively. The sucrose content of tomato seedlings under WBL was increased by 60.4%, compared with that under WL. In conclusion, 12 h·d − 1 supplementary light provided by combinations of white and blue LEDs led to compact morphological characteristics, superior mechanical properties, and satisfactory growth performance. Our fi ndings provide an available lighting strategy to obtain the desired morphological and quality properties of tomato seedlings grown in the seasons with insuffi cient light.

      • KCI등재

        Progress on reproductive modes of sarcosaphagous flies

        Yang Li,Ren Lipin,Shang Yanjie,Zhang Changquan 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

        The reproduction strategies of invertebrates, oviparity, ovoviviparity and viviparity, always reflect the rela tionship between individuals and their surroundings. There is plasticity in the reproductive strategies of sarco saphagous flies as they adjust to rapidly changing circumstances. The transition from oviparity to ovoviviparity or viviparity involves numerous changes in physiology, morphology and immunology. Demonstrating these processes can make the application of entomology work in forensic practice more reliable. This essay reviews means of reproduction in sarcosaphagous flies and identifies related features. It is shown that not only the reproduction traits, such as fast location of carrion, and uncommon number of ovaries and oogenesis, but also some morphological features are related to viviparity. In general, viviparous flies have larger adult bodies but smaller eggs and chorions. Moreover, the length of terminalia and the shape of the vagina also varies among those three modes. Reproductive plasticity is a bridge between the three reproductive modes, and it can greatly influence the inference of the post-mortem interval (PMImin).

      • KCI등재

        Deletion of the oligopeptide transporter Lmo2193 decreases the virulence of Listeria monocytogenes

        Honghuan Li,Yanjie Qiao,Dongdong Du,Jing Wang,Xun Ma 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.6

        Background: Listeria monocytogenes is a gram-positive bacterium that causes listeriosis mainly in immunocompromised hosts. It can also cause foodborne outbreaks and has the ability to adapt to various environments. Peptide uptake in gram-positive bacteria is enabled by oligopeptide permeases (Opp) in a process that depends on ATP hydrolysis by OppD and F. Previously a putative protein Lmo2193 was predicted to be OppD, but little is known about the role of OppD in major processes of L. monocytogenes, such as growth, virulence, and biofilm formation. Objectives: To determine whether the virulence traits of L. monocytogenes are related to OppD. Methods: In this study, Lmo2193 gene deletion and complementation strains of L. monocytogenes were generated and compared with a wild-type strain for the following: adhesiveness, invasion ability, intracellular survival, proliferation, 50% lethal dose (LD50) to mice, and the amount bacteria in the mouse liver, spleen, and brain. Results: The results showed that virulence of the deletion strain was 1.34 and 0.5 orders of magnitude higher than that of the wild-type and complementation strains, respectively. The function of Lmo2193 was predicted and verified as OppD from the ATPase superfamily. Deletion of lmo2193 affected the normal growth of L. monocytogenes, reduced its virulence in cells and mice, and affected its ability to form biofilms. Conclusions: Deletion of the oligopeptide transporter Lmo2193 decreases the virulence of L. monocytogenes. These effects may be related to OppD's function, which provides a new perspective on the regulation of oligopeptide transporters in L. monocytogenes.

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