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      • KCI등재

        Tannin–Thioctic Acid Network Hydrogels with Antibacterial and Hydrophobic Properties

        Xinyi Hu,Que Kong,Rong Li,Change Zhou,Zhiguang Li 한국섬유공학회 2023 Fibers and polymers Vol.24 No.10

        Making a multifunctional hydrogel-based wound dressing is a long-term research goal. Therefore, it is of great significance to develop an ideal wound dressing with desirable biocompatibility, adhesive property, antibacterial property and simple production. Herein, molecular network crosslinking hydrogels were achieved through the nucleophilic addition of polyphenol-sulfur radical using tannic acid and thioctic acid as matrix. The multifunctional tannic–thioctic acid (TATA) hydrogels with excellent rheological properties were prepared by further modification of antibacterial and hydrophobic properties. The successful cross-linking of the molecules was confirmed by infrared spectroscopy, Raman spectroscopy and energy dispersive X-ray spectroscopy (EDX). Complex hydrogels had certain hydrophobic properties, which can slowly absorb wound tissue fluid and keep the wetness of the wound. In addition, the hydrogel had good rheological, antibacterial and antioxidant properties, and also improved blood clotting effect and biocompatibility. These results indicated that TATA hydrogel had the potential prospect to be used as a novel wound dressing for a wide range of medical applications.

      • KCI등재

        Factors Affecting the Performance of HJT Silicon Solar Cells in the Intrinsic and Emitter Layers: A Review

        Xinyi Fan,라벨로 마테우스,Yifan Hu,Muhammad Quddamah Khokhar,김영국,이준신 한국전기전자재료학회 2023 Transactions on Electrical and Electronic Material Vol.24 No.2

        Recently, the focus of solar cell research has shifted from Passivated Emitter and Rear Cell and Passivated Emitter and Rear Locally-diffused solar cells to Heterojunction with Intrinsic Thin Layer solar cells. Compared to the already mass-produced Passivated Emitter and Rear Cell and Passivated Emitter and Rear Locally-diffused solar cells, the passivation with the intrinsic thin layer of amorphous on the wafer surface, the continuous improvement of the emitter thickness, and doping concentration have enabled Heterojunction with Intrinsic Thin Layer solar cells to obtain open-circuit voltage above 750 mV while maintaining a short circuit current density of ~ 40 mA/cm2 and an Fill Factor of ~ 84%. This leads to a theoretical conversion efficiency of 27.5% (monolithic) to 29% (tandem), which is much higher than the theoretical final conversion efficiency of ~ 24.5% achieved by Passivated Emitter and Rear Cell and Passivated Emitter and Rear Locally-diffused solar cells at a short-circuit voltage of 706 mV. To further approach the theoretical maximum efficiency, improvements, and optimization of the fabrication process, as well as change in material of the front emitter layer and thus the band gap, conductivity, and defect density can be adopted. Efficiencies of up to 28.27% were achieved using hydrogenated nanocrystalline silicon with a bandgap of 1.9 eV as the emitter layer.

      • KCI등재

        Expression of DNA Damage Response Proteins and Associations with Clinicopathologic Characteristics in Chinese Familial Breast Cancer Patients with BRCA1/2 Mutations

        Xinyi Zhu,Tian Tian,Miao Ruan,Jia Rao,Wentao Yang,Xu Cai,Menghong Sun,Guangqi Qin,Zhonghua Zhao,Jiong Wu,Zhimin Shao,Ruohong Shui,Zhen Hu 한국유방암학회 2018 Journal of breast cancer Vol.21 No.3

        Purpose: The characteristic expression of DNA damage response proteins in familial breast cancers with BRCA1, BRCA2, or non-BRCA1/2 mutations has not been analyzed in Chinese patients. Our study aimed to assess the differential expression of microcephalin 1 (BRIT1), ATM serine/threonine kinase (ATM), checkpoint kinase 2 (CHEK2), BRCA1, RAD51 recombinase (RAD51), and poly (ADP-ribose) polymerase 1 (PARP-1) and establish the profile of Chinese familial breast cancers with different mutation status. Methods: We constructed five tissue microarrays from 183 familial breast cancer patients (31 with BRCA1 mutations; 14 with BRCA2 mutations, and 138 with non-BRCA1/2 mutations). The DNA response and repair markers used for immunohistochemistry analysis included BRIT1, ATM, CHEK2, BRCA1, RAD51, and PARP-1. The expressions of these proteins were analyzed in BRCA1/2 mutated tumors. The association between pathologic characteristics with BRCA1/2 mutation status was also analyzed. Results: In familial breast cancer patients, BRCA1 mutated tumors were more frequent with high nuclear grade, estrogen receptor/progesterone receptor/human epidermal growth factor receptor 2 negative, low Ki-67, and positive CK5/6. BRCA1 mutated tumors had lower CHEK2 and higher cytoplasmic BRIT1 expression than BRCA2 and non-BRCA1/2 mutation tumors. BRCA2-associated tumors showed higher CHEK2 and cytoplasmic RAD51 expression than those in other groups. Nuclear PARP-1 expression in BRCA1/2-associated tumors was significantly higher than in non-BRCA1/2 mutation tumors. Moreover, we found quite a few of negative PARP-1 expression cases in BRCA1/2 mutated groups. Conclusion: The clinicopathologic findings of BRCA1-associated Chinese familial breast cancers were similar to the results of other studies. Chinese familial breast cancer patients with BRCA1/2 mutations might have distinctive expression of different DNA damage response proteins. The reduced expression of PARP-1 in Chinese BRCA1/2 mutated breast cancer patients could influence the therapeutic outcome of PARP-1 inhibitors.

      • KCI등재

        Biofilm formation in food processing plants and novel control strategies to combat resistant biofilms: the case of Salmonella spp.

        Xinyi Pang,Xin Hu,Xueying Du,Chenglong Lv,육현균 한국식품과학회 2023 Food Science and Biotechnology Vol.32 No.12

        Salmonella is one of the pathogens that cause many foodborne outbreaks throughout the world, representing an important global public health problem. Salmonella strains with biofilm-forming abilities have been frequently isolated from different food processing plants, especially in poultry industry. Biofilm formation of Salmonella on various surfaces can increase their viability, contributing to their persistence in food processing environments and cross-contamination of food products. In recent years, increasing concerns arise about the antimicrobial resistant and disinfectant tolerant Salmonella, while adaptation of Salmonella in biofilms to disinfectants exacerbate this problem. Facing difficulties to inhibit or remove Salmonella biofilms in food industry, eco-friendly and effective strategies based on chemical, biotechnological and physical methods are in urgent need. This review discusses biofilm formation of Salmonella in food industries, with emphasis on the current available knowledge related to antimicrobial resistance, together with an overview of promising antibiofilm strategies for controlling Salmonella in food production environments.

      • KCI등재

        Effects of Exogenous Organic Acids on the Growth and Antioxidant System of Cosmos bipinnatus under Cadmium Stress

        Jiani Hu,Xinyi Gao,Yajie Yue,Xiaoyu Ming,Linjie Yue,Lijuan Yang,Xue Xiao,Xiaofang Yu 한국원예학회 2022 원예과학기술지 Vol.40 No.5

        Cadmium pollution in China’s urban green spaces is extremely severe, causing a significant increase in the risk of urban environmental pollution. Applying organic acids under Cd stress conditions improves the activity of the major antioxidant enzymes in the AsA-GSH cycle signi- ficantly. In this study, Cosmos bipinnatus seedlings were cultured in a nutritive medium containing 40 µmol·L-1 Cd. They were subsequently supplemented with different concentrations of citric acid and malic acid (0, 0.5, 1.0, 2.0 mmol L-1 ) to analyze the roles of the organic acids in regulating the AsA-GSH cycle involved in plant resistance to Cd stress. Exogenous organic acids inhibited the growth of C. bipinnatus in a dose-dependent manner. AsA, GSH, and GR in the leaves decreased dramatically at high malic acid concentrations (2 mol L-1 ). The contents of GSH and GR and the APX activities showed a downward trend when the seedlings were treated with 0.5–2 mmol·L-1 of citric acid. However, AsA exhibited contrasting results under these conditions. Notably, both the antioxidant and enzyme activities were reduced considerably to a minimum when the citric acid concentration was 2 mmol·L-1 . Low concentrations of exogenous acids increased the activities of APX and GR in the leaves of C. bipinnatus, thus increasing the contents of ASA and GSH. Such increases boost the efficiency of the ASA-GSH cycle in relieving the toxic effect of cadmium on C. bipinnatus. Cadmium pollution in China’s urban green spaces is extremely severe, causing a significant increase in the risk of urban environmental pollution. Applying organic acids under Cd stress conditions improves the activity of the major antioxidant enzymes in the AsA-GSH cycle signi- ficantly. In this study, Cosmos bipinnatus seedlings were cultured in a nutritive medium containing -1 40 µmol·L Cd. They were subsequently supplemented with different concentrations of citric acid -1 and malic acid (0,0.5,1.0,2.0 mmol L ) to analyze the roles of the organic acids in regulating the AsA-GSH cycle involved in plant resistance to Cd stress. Exogenous organic acids inhibited the growth of C. bipinnatus in a dose-dependent manner. AsA, GSH, and GR in the leaves decreased -1 dramatically at high malic acid concentrations (2 mol L ). The contents of GSH and GR and the -1 APX activities showed a downward trend when the seedlings were treated with 0.5–2 mmol·L of citric acid. However, AsA exhibited contrasting results under these conditions. Notably, both the antioxidant and enzyme activities were reduced considerably to a minimum when the citric acid -1 concentration was 2 mmol·L . Low concentrations of exogenous acids increased the activities of APX and GR in the leaves of C. bipinnatus, thus increasing the contents of ASA and GSH. Such increases boost the efficiency of the ASA-GSH cycle in relieving the toxic effect of cadmium on C. bipinnatus.

      • KCI등재

        Cooperative Task Scheduling and Planning Considering Resource Conflicts and Precedence Constraints

        Donghui Li,Hu Su,Xinyi Xu,Qingbin Wang,Jie Qin,Wei Zou 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.9

        The robot-task-sequencing planning problem is investigated in this paper, where multi-robot tasks with resource conflicts and precedence constraints are involved making the problem challenging and complex. An effective approach is proposed to minimize the production cycle time while handling the high complexity effectively. The approach decouples the entire problem into simpler ones and then solves them separately to obtain the final solution. Firstly, given the multi-robot tasks, how to coordinate the operation of each single robot is determined. This is achieved by searching the shortest path in the graph where the tasks are organized in the optimal order without the consideration of resource constraints. Then, the resource allocation is modeled as a constrained assignment problem with the objective of minimal cycle time, which is solved with graph optimization. Consequently, the best-fit robot configurations for task execution are selected according to a heuristic optimality metric, based on which the task execution sequence obtained in previous steps is re-optimized. Finally, the robots involved in the task are regarded as a whole to deduce feasible trajectories. Experimental results demonstrate that the proposed approach can generate solutions where the robot can complete the given tasks effectively with feasible scheduling. Moreover, the proposed approach is successfully implemented in a pragmatic system which tests signals at both ends of components in a circuit board.

      • KCI등재

        Recent advances in feed and nutrition of beef cattle in China — A review

        Gao Qian,Liu Hu,Wang Zuo,Lan Xinyi,An Jishan,Shen Weijun,Wan Fachun 아세아·태평양축산학회 2023 Animal Bioscience Vol.36 No.4

        The beef cattle industry in China has advanced remarkably since its reform and opening up; consequently, China has become the world’s third-largest beef cattle producer. China is also one of the countries with the most substantial research input and output in the field of beef cattle feed and nutrition. The progress and innovation by China in the research field of beef cattle feed and nutrition have undoubtedly promoted the development of the domestic beef cattle industry. This review summarizes recent advances in feed resource development, nutrient requirements, and nutritional regulation of beef cattle in China. Limitations in current research and perspectives on future work are also discussed.

      • SCIESCOPUSKCI등재
      • KCI등재

        Improvement of Storage Performance by HfO2/Al2O3 Stacks as Charge Trapping Layer for Flash Memory- A Brief Review

        Fucheng Wang,산얄 심피,최지원,조재웅,Yifan Hu,Xinyi Fan,Suresh Kumar Dhungel,이준신 한국전기전자재료학회 2023 전기전자재료학회논문지 Vol.36 No.3

        As a potential alternative to flash memory, HfO2/Al2O3 stacks appear to be a viable option as charge capture layers in charge trapping memories. The paper undertakes a review of HfO2/Al2O3 stacks as charge trapping layers, with a focus on comparing the number, thickness, and post-deposition heat treatment and γ-ray and white x-ray treatment of such stacks. Compared to a single HfO2 layer, the memory window of the 5-layered stack increased by 152.4% after O2 annealing at ±12 V. The memory window enlarged with the increase in number of layers in the stack and the increase in the Al/Hf content in the stack. Furthermore, our comparison of the treatment of HfO2/Al2O3 stacks with varying annealing temperatures revealed that an increased annealing temperature resulted in a wider storage window. The samples treated with O2 and subjected to various γ radiation intensities displayed superior resistance. and the memory window increased to 12.6 V at ±16 V for 100 kGy radiation intensity compared to the untreated samples. It has also been established that increasing doses of white x-rays induced a greater number of deep defects. The optimization of stacking layers along with post-deposition treatment condition can play significant role in extending the memory window.

      • KCI등재

        Ultrafast dynamics control on ablation of Cu using shaped femtosecond pulse trains

        Deng Jiannan,Qi Hongxia,Liu Xinyi,Li Xiaoyi,Tong Qiunan,Lian Zhenzhong,Li Juan,Bo Jinqiu,Fei Dehou,Chen Zhou,Hu Zhan 한국물리학회 2021 Current Applied Physics Vol.26 No.-

        The ablation processes of Cu film are investigated using temporal shaped femtosecond pulse trains. The depth is modulated by changing the number and interval of the sub-pulses. The underlying ultrafast dynamic processes are discussed based on plasma shielding and electron multiple heating mechanisms. When the sub-pulse interval is less than 0.4 ps electron multiple heating is the dominant mechanism, while the plasma shielding dominates the subsequent ablation processes when the sub-pulse interval is larger than 0.4 ps. The curve of depth obtained by three pulse trains shows more significant oscillation as the function of sub-pulse interval under the lowfluence. We propose that the oscillation of depth is due to the coherent phonon oscillation excited by the pulse train. The study provides a basis for giving insight into the ultrafast dynamics for improving micromachining and nano-fabrications using shaped femtosecond pulse trains.

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