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      • KCI등재후보

        중국 생활체육 테니스 참가자의 자기개념과 참가동기가 운동지속에 미치는 영향

        도영영 ( Tao Ying-ying ),곽한병 ( Kwak Han-pyong ) 미래융합통섭학회 2021 현대사회와 안전문화 Vol.4 No.3

        연구목적 본 연구는 생활체육 테니스 참가자의 자기개념과 참가동기가 운동지속에 미치는 영향을 규명하는데 목적이 있다. 연구방법 연구 대상자은 중국 흑룡강성 하얼빈시(哈尔滨市), 다칭시(大庆市)의의 생활 체육 테니스 참가자 556명을 대상으로 하였으며, 조사기간은 2021.02.0~2021.02.24까지 진행하였다. 조사 대상의 표집 방법은 비확률 표집방법 중에서 연구 목적에 따라 편의표본추출법을 이용하였다. 연구의 목적을 달성하기 위한 자료처리 방법으로는 빈도분석, 신뢰도 분석, 확인적 요인분석, 상관관계 분석, 그리고 다중회귀분석 방법을 사용하였다. 결론 첫째, 생활체육 테니스 참가자의 자기개념의 하 위요인 중 가정자기, 심리자기, 사회자기는 운동지속에 정적인 상관관계가 나타났고, 도덕자기와 자기비판은 부적인 상관관계가 나타났다. 참가동기의 하 위요인 중 건강동기, 사회동기, 재미동기는 운동지속에 정적인 상관관계가 나타났다. 둘째, 중국 생활체육 테니스 참가자의 자기개념은 운동지속에 영향을 미친다. 즉, 가정 자기, 심리 자기가 높을수록 정서체험은 강화되며, 도덕 자기와 심리 자기가 높을수록 행위습관은 강화된다. 셋째, 중국 생활체육 테니스 참가자의 참가동기는 운동지속에 영향을 미친다. 즉, 건강동기와 재미동기가 강할수록 정서체험과 행위습관은 강화된다. PURPOSE The purpose of this study is to investigate the effects of self-concept and participation motivation on exercise continuity of tennis participants in life sports. METHOD The subjects of this study were 556 sports tennis participants in Harbin City, Heilongjiang Province, China, and the survey period was 2021.02.01. ~ It was carried out until 2021.02.24. Convenience Sampling Method was used according to the purpose of the study among non-probability sampling methods. Of the 556 questionnaires, 510 questionnaires were analyzed, excluding 46 unreliable questionnaires. Frequency analysis, reliability analysis, confirmatory factor analysis, correlation analysis, and multiple regression analysis were used as data processing methods to achieve the purpose of the study. RESULT First, among the sub-factors of self-concept of tennis participants in sports and sports, there were positive correlations between home self, psychological self, and social self in exercise continuity, and negative correlation between moral self and self-criticism. Among the sub-factors of participation motive, health motive, social motive, and fun motive showed a positive correlation with exercise continuity. Second, it was found that the self-concept of life sports tennis participants had an effect on exercise continuity. The family self, psychological self, and moral self were found to have a positive influence. Third, it was found that the participation motivation of the tennis participants in life sports had an effect on exercise continuity. In other words, among the sub-factors of participation motivation, health motivation and fun motivation were found to have an influence.

      • KCI등재

        Deficiency of Follistatin-Like Protein 1 Accelerates the Growth of Breast Cancer Cells at Lung Metastatic Sites

        Ying Zhang,Xiaozhou Xu,Ying Yang,Jie Ma,Lulu Wang,Xiangzhi Meng,Bing Chen,Ling Qin,Tao Lu,Yan Gao 한국유방암학회 2018 Journal of breast cancer Vol.21 No.3

        Purpose: Follistatin-like protein 1 (FSTL1) is a secreted glycoprotein that has been shown to play a role in various types of cancer. However, the clinical significance and function of FSTL1 in breast cancer have not been reported. We investigated the role of FSTL1 in breast cancer in this study. Methods: Enzyme-linked immunosorbent assays, western blot analysis, and reverse transcription polymerase chain reaction were used to monitor the expression of FSTL1 in breast cancer tissue and in serum samples from breast cancer patients. We employed a 4T1 breast cancer model and Fstl1+/− mice for in vivo studies. Hematoxylin and eosin staining, western blot analysis, and RNA sequencing were used to analyze the effect of FSTL1 on primary tumor growth and lung metastasis. Results: We demonstrated that the expression of FSTL1 is reduced in both the breast cancer tissue and the serum of breast cancer patients. We showed that reduced levels of FSTL1 in serum correlate with elevated expression of Ki-67 and epidermal growth factor receptor (EGFR) in cancer tissues. Moreover, lowered expression of FSTL1 was associated with decreased survival in breast cancer patients. Experiments on the Fstl1+/− mouse model established that FSTL1 deficiency had no effect on primary tumor growth, but increased the lung metastases of breast cancer cells, resulting in reduced survival of tumor-bearing mice. RNA sequencing found significantly reduced expression of Egln3 and increased expression of EGFR in Fstl1+/− mice. Thus, our results suggest that FSTL1 may affect the expression of EGFR through Egln3, inhibiting the proliferation of breast cancer cells at lung metastatic sites. Conclusion: In conclusion, we suggest a suppressor role of FSTL1 in breast cancer lung metastasis. Furthermore, FSTL1 may represent a potential prognostic biomarker and a candidate therapeutic target in breast cancer patients.

      • KCI등재

        Sulfonated-polysulfone membrane surface modification by employing methacrylic acid through UV-grafting: Optimization through response surface methodology approach

        Ying Tao Chung,Abdul Wahab Mohammad,Law Yong Ng 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

        Membrane surface modification through UV-grafting method was studied and optimized using response surface methodology (RSM) approach. Sulfonated-polysulfone (SPS) membrane was modified through grafting process by employing methacrylic acid (MAA) monomer solution under the exposure of UV light. The parameters used were the concentration of MAA in the range of 0–6 wt% and UV activation time of 0–50 min. The optimized parameters from RSM were 2.61 wt% of MAA and 21.10 min of UV activation time. The optimized water permeability obtained was 8.75 L m 2 h 1 bar 1, while the rejection percentages for humic acid, NaCl and MgSO4 solution were 95.0%, 65.7% and 48.3%, respectively.

      • KCI등재

        Loop Closure Detection Based on Image Covariance Matrix Matching for Visual SLAM

        Tao Ying,Huaicheng Yan,Zhichen Li,Kaibo Shi,Xiangsai Feng 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.11

        Loop closure detection is an indispensable part of visual simultaneous location and mapping (SLAM). Correct detection of loop closure can help mobile robot to reduce the problem of cumulative pose drift. At present, the main method for detecting visual SLAM loop closure is the bag of words (BoW) model, but it lacks the spatial distribution information of local features of the image, and the scale will become larger and larger with the increase of data, resulting in the slow operation speed. In order to solve these problems, the image histogram and the key region covariance matrix matching method are used to visually detect the loop closure combined with the global and local image features. In this paper, three different place recognition techniques are studied: histogram only, image covariance matrix matching (ICMM) and cluster loop. Experiments on real datasets show that the proposed method of detecting the loop closure is better than the traditional methods in detecting accuracy and recalling rate, which also improves the operation effect of the SLAM algorithm.

      • KCI등재

        Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment

        Ying Xing,Jie Ming,Tao Liu,Nana Zhang,Dingjun Zha,Ying Lin 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.9

        Purpose: Previous reports have shown that hyperglycemia-induced inhibition of transient receptor potential vanilloid sub type 4 (TRPV4), a transient receptor potential ion channel, affects the severity of hearing impairment (HI). In this study, we explored the role of TRPV4 in HI using HEI-OC1 cells exposed to high glucose (HG). Materials and Methods: HEI-OC1 cells were cultured in a HG environment (25 mM D-glucose) for 48 hours, and qRT-PCR and Western blotting were used to analyze the expression of TRPV4 at the mRNA and protein level. TRPV4 agonist (GSK1016790A) or antagonist (HC-067047) in cultured HEI-OC1 cells was used to obtain abnormal TRPV4 expression. Functional TRPV4 activity was assessed in cultured HEI-OC1 cells using the MTT assay and a cell death detection ELISA. Results: TRPV4 agonists exerted protective effects against HG-induced HI, as evidenced by increased MTT levels and inhibition of apoptosis in HEI-OC1 cells. TRPV4 overexpression significantly increased protein levels of phosphorylated p38 mitogen-activatedprotein kinase (p-p38 MAPK), while TRPV4 antagonists had the opposite effect. Our results indicated that TRPV4 is a hyperglycemia-related factor that can inhibit cell proliferation and promote cell apoptosis by activating the MAPK signaling pathwayin HEI-OC1 cells. Conclusion: Our results show that the overexpression of TRPV4 can attenuate cell death in HEI-OC1 cells exposed to HG.

      • Kiln Landscape Evolution Simulation Based on Particle Swarm Optimization and Cellular Automata Model

        Tao Liu,Xuan Xiao,Donglan Ying 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.1

        Due to the less accessibility to the data, relatively little literature has been found on how the ancient kiln site evolves. To understand how land has transformed kiln in ancient Jingdezhen DongHe River Basin from the Yuan Dynasty to the Ming Dynasty, we create virtual maps of ancient study area and present such concepts that unambiguously realize a combination model. In this model, Model parameters and neighborhood rules are obtained with the cellular automata model melt modified Particle Swarm Optimization algorithm. Meanwhile, model performance is evaluated using Moran’s I index estimation for selected landscape pattern indices and make a comparative analysis of different evolution with different number of candidate site and different conversion threshold. In overall, the model that we propose is effective and feasible in simulating kiln landscape evolution in ancient when Geographic Information and System information are lacking.

      • KCI등재

        Intravenous patient-controlled analgesia hydromorphone combined with pregabalin for the treatment of postherpetic neuralgia: a multicenter, randomized controlled study

        ( Ying Huang ),( Chenjie Xu ),( Tao Zeng ),( Zhongming Li ),( Yanzhi Xia ),( Gaojian Tao ),( Tong Zhu ),( Lijuan Lu ),( Jing Li ),( Taiyuan Huang ),( Hongbo Huai ),( Benxiang Ning ),( Chao Ma ),( Xinx 대한통증학회 2021 The Korean Journal of Pain Vol.34 No.2

        Background: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants, and lidocaine patches in reducing PHN, many patients still face intractable pain disorders. In this randomized controlled study, we evaluated whether hydromorphone through intravenous patient-controlled analgesia (IV PCA) was effective in relieving PHN. Methods: Patients with PHN were randomly divided into two groups, one group received oral pregabalin with IV normal saline, another group received oral pregabalin with additional IV PCA hydromorphone for two weeks. Efficacy was evaluated at 1, 4, and 12 weeks after the end of the treatments. Results: Two hundred and one patients were followed up for 12 weeks. After treatment, numerical rating scale (NRS) score of patients in the hydromorphone group was significantly lower than that of the control group, and the difference of NRS scores between the two groups was statistically significant at 4 and 12 weeks after treatment. The frequency of breakthrough pain in the hydromorphone group was significantly lower than that in the control group 1 and 4 weeks after treatment. After treatment, the quality of sleep in the hydromorphone group was significantly improved compared with the control group. The most common adverse reactions in the hydromorphone group were dizziness and nausea, with no significant respiratory depression. Conclusions: IV PCA hydromorphone combined with oral pregabalin provides superior pain relief in patients with PHN, which is worthy of clinical application and promotion.

      • A Novel Integration Model for the Simulation of Kiln Landscape in Ancient Fu Liang Area

        Tao Liu,Xuan Xiao,Donglan Ying 보안공학연구지원센터 2014 International Journal of Smart Home Vol.8 No.6

        Re-creation of the land use transformation at different periods in time is valuable for revealing how policy change influence ancient Fu Liang kiln. To date, there has been little focused on the model of historical Fu Liang kiln change. On the contrary, current research has emphasized that the transformation process of kiln has been described by literal presentation. However, Dynamical and visual model can provide insights into kiln change processes and are valuable for land use transformation. For this reason, we create virtual maps of ancient Fu Liang area and propose such constructs to unambiguously denote a novel integration model. In this model, ancient virtual maps are created by ARCGIS10.0 software and PCI9.0 software, land use changes are performed through cellular automata, decision processes are controlled beyond the multi- agent, spatial optimization is represented by particle swarm optimization. We use the simulation approach to recreate the kiln transformation of Fu Liang, Jiang Xi, annually from 1271 to 1554. The simulation of the model is of richer changing hierarchy and can better reflect the whole process from the first to the last firing, and can be used to preferable create dynamic model and theory. Additionally, the model can better reflect the interaction of the political situation, institutions and the natural environment.

      • Expression Profile and Potential Roles of EVA1A in Normal and Neoplastic Pancreatic Tissues

        Tao, Ming,Shi, Xue-Ying,Yuan, Chun-Hui,Hu, Jia,Ma, Zhao-Lai,Jiang, Bin,Xiu, Dian-Rong,Chen, Ying-Yu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

        Background: EVA1A (eva-1 homolog A) is a novel gene that regulates programmed cell death through autophagy and apoptosis. Our objective was to investigate the expression profiles and potential role of EVA1A in normal and neoplastic human pancreatic tissues. Materials and Methods: The expression pattern of EVA1A in normal pancreatic tissue was examined by indirect immunofluorescence and confocal microscopy. Protein levels in paraffin-embedded specimens from normal and diseased pancreatic and matched non-tumor tissues were evaluated by immunohistochemistry. Results: EVA1A colocalized with glucagon but not with insulin, demonstrating production in islet alpha cells. Itwas strongly expressed in chronic pancreatitis, moderately or weakly expressed in the plasma membrane and cytoplasm in pancreatic acinar cell carcinoma, and absent in normal pancreatic acinar cells. Although the tissue architecture was deformed, EVA1A was absent in the alpha cells of pancreatic ductal adenocarcinomas, intraductal papillary mucinous neoplasms, mucinous cystadenomas, solid papillary tumors and pancreatic neuroendocrine tumors. Conclusions: EVA1A protein is specifically expressed in islet alpha cells, suggesting it may play an important role in regulating alpha-cell function. The ectopic expression of EVA1A in pancreatic neoplasms may contribute to their pathogenesis and warrants further investigation.

      • Novel High-throughput Baculovirus Expression Vector based on Bombyx mori Nucleopolyhedrovirus

        Xue Ying Tao,Jae Young Choi,Woo Jin Kim,Joo Hyun Lee,Qin Liu,Song Eun Kim,Saes Byeol An,Seok Hee Lee,Zhen Li Fu,Yeon Ho Je 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.10

        The baculovirus expression system is one of the most popular methods used for the production of recombinant proteins but has several complex steps which have proved inherently difficult to meet a multi-parellel process. We have developed a novel recombinant bacmid, bEasyBm that enabling easy and fast generation of pure recombinant virus without any purification step. In the bEasyBm, attR recombination sites were introduced to facilitate the generation of recombinant viral genome by in vitro transposition. Moreover, extracellular RNase gene from bacillus amyloliquefaciens, barnase, was expressed under the control of Cotesia plutellae bracovirus early promoter. Therefore, only when the barnase gene was replaced to gene of interest, the bEasyBm could replicate in host insect cells. When the bEasyBm was transposed with pDualBac-EGFP and pDualBac-LUC respectively, there were no non-recombinant backgrounds were detected from unpurified BmEasy-EGFP or BmEasy-LUC stocks. In addition, the resulting recombinant virus, BmEasy-EGFP, showed comparable level of EGFP expression efficiency with the plaque-purified recombinant virus, BmEGFP, which was constructed using bBmGOZA system. Based on these results, high-throughput condition for generation of multiple recombinant viruses in a time was established.

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