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Suyeon Park,Ji Yong Ahn,Young Eun Ahn,전상범,Sang Soo Lee,Hwoon-Yong Jung,Jin Ho Kim 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.2
Cerebral air embolism is an extremely rare complication of endoscopic procedure and often life threatening. We present two cases of cerebral infarction due to air embolization caused by an endoscopic intervention. The first case occurred during esophageal balloon dilatation for the treatment of a stricture of an anastomosis site in a 59-year-old man and the second case occurred during endoscopic papillary balloon dilatation in a 69-year-old man who had distal common bile duct stones. After the procedure, cardiopulmonary instability and altered mental status were observed in both patients, and cerebral air embolism was diagnosed in both cases. Hyperbaric oxygen therapy was started in the first case, and high FiO2 therapy was applied in the second case. Although this complication is rare, patient outcomes can be improved if physicians are aware of this potential complication, and immediately begin proper management.
안수연(Ahn Suyeon) 한국아동청소년문학학회 2017 아동청소년문학연구 Vol.- No.20
North Korean defectors are increasing. From the initial ‘political defection’, to the ‘economic defection’, and ‘immigration defect’ is recent fashion. The North Korean fairy tales are stories about children who have escaped from North Korea. North Korean defectors who have escaped to North Korea settled in China, third countries, or Korea. The settled North Korean child can not adapt to the society, and becomes a ‘marginal man’. They have not forgotten the culture of the past and have not yet accepted the culture of the present society. At the boundary where they stand, the culture of North Korea and the culture of Korean society collide. The suffering of a North Korean defector children as a marginal man is relatively more severe than that of an adult. North Korean defector children suffer from inferiority. They suffer from the trauma of past suffering. Language is the biggest factor that makes a North Korean child experience a culture clashes. Subtle differences between Korean and North Korean languages cause unnecessary conflicts. North Korean defector children feel cultural alienation. The reason why the cultural alienation of the defector children should be resolved is clear. A healthy society does not allow internal cultural clashes to separate society itself. Conflicts should be for integration. The defector fairy tales suggest the ways for North Korean defectors to overcome alienation and conflict. Defector children in fairy tales escape from alienation through the disappearance of inferiority. The disappearance of inferiority is possible by establishing a relationship with another children. By recognizing and communicating with each other, homogeneity can be obtained. If they sympathize with each other, the inferiority of the North Korean defectors disappears. Various cultures coexist in a multicultural society. Cultural clashes occur everywhere. When various problems arising from cultural clashes are overcomed through empathy and communication, society can achieve internal integration. It stands out from the conflict and becomes healthier. This method of resolving conflicts proposed by defector children tales can be equally applied to multicultural families. The North Korean fairy tale began as a literary accusation that notifies the misery of the North Korea. But by presenting the method of internal integration, it secured the status of literature of communication and sympathy. After that, North Korean fairy tales will be changed to show how diversity acquired in the process of overcoming the cultural conflict serves as a potential to develop society. This direction is consistent with the direction of our society growth that has already become a multicultural society.
안수연(Suyeon Ahn),김명순(Myung-Soon Kim),박병준(Byung-Joon Park),차호정(Hojung Cha) 한국정보과학회 2001 한국정보과학회 학술발표논문집 Vol.28 No.1A
본 논문은 웹을 이용하는 사용자들의 웹 문서 액세스 패턴을 파악하여 캐슁을 할 대상을 결정하고 관리하는 적응력이 있는 웹 캐슁 서버를 제안하고 구현한다. 빈번히 나타나는 순서열을 찾는 데이터 마이닝 기법을 캐슁 서버의 로그에 적용하여 순차적으로 액세스되는 웹 객체들을 찾아낸 다음, 필요한 경우 이들을 캐쉬 내에 선반입함으로써 히트율을 높이고, 따라서 캐쉬의 효율을 증가시킬 수 있는 캐슁 서버의 모델을 제시한다. 그리고 초기실험을 통하여, 제안된 캐슁 서버의 효율이 기존 캐슁서버에 비해 실제 상당히 증가함을 보였다.
안수연(Suyeon Ahn),박병준(Byung-Joon Park),차호정(Hojung Cha) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1A
본 논문에서는 MPEG-4 컨텐츠 스트리밍을 목적으로 MPEG-4 시스템 사양을 기반으로한 컨텐츠 저작 시스템을 설계하고 구현하였다. 구현된 컨텐츠 저작 시스템은 사용자가 쉽고 편리하게 컨텐츠를 저작할수 있는 인터페이스를 제공하고 파일 재생을 위해 MPEG-4 파일을 생성한다. 또한 스트리밍을 위해서 각각의 미디어 데이터를 싱크레이어 패킷화된 미디어 데이터, BIFS, OD, IOD 파일로 생성하여 스트리밍 시에 사용하여 스트리밍이 가능하도록 하였다.
중학생이 지각한 부모양육태도가 우울에 미치는 영향: 학업무기력과 사회적 위축의 매개효과
김수연(Suyeon Kim),안도희(Doehee Ahn) 중앙대학교 한국교육문제연구소 2021 한국교육문제연구 Vol.39 No.3
본 연구의 목적은 중학생이 지각한 부모양육태도와 우울 간의 관계에서 학업무기력 및 사회적 위축의 매개효과를 탐색하였다. 이를 위해 한국아동청소년패널조사(Korean Children & Youth Panel Survey: KCYPS) 2018년의 중학교 1학년 총 2,590명(남: 1,405명, 여: 1,185명)을 분석하였다. 본 연구결과는 다음과 같다. 첫째, 부모의 긍정적 양육태도는 우울, 학업무기력, 사회적 위축과 유의한 부적 상관이 있는 것으로 나타났다. 반면, 부모의 부정적 양육태도는 우울, 학업무기력, 사회적 위축과 유의한 정적 상관이 있는 것으로 나타났다. 둘째, 부모양육태도와 우울 간의 관계에서 학업무기력과 사회적 위축이 매개하는 것으로 나타났다. 마지막으로, 부모양육태도, 우울, 학업무기력, 사회적 위축 간의 관계에서 성별 차이가 존재하는 것으로 밝혀졌다. 본 연구결과를 통해 중학생의 우울은 물론 학업무기력과 사회적 위축을 예방하는 데 있어, 긍정적인 부모양육태도의 중요성이 입증되었다. 이와 같은 본 연구결과는 중학생의 우울을 예방하기 위한 기초자료로 활용될 수 있을 것으로 기대된다. The purpose of this study was to examine the mediating effects of academic helplessness and social withdrawal in the relationship between parenting styles and depression of middle school students. Two thousand five hundred ninety middle school students from a Korean Children and Youth Panel Survey were assessed in the study. The results of the study were as follows. First, parenting styles, depression, academic helplessness, and social withdrawal showed statistically significant correlations among them. Positive parenting styles had negative correlations with depression, academic helplessness, and social withdrawal, whereas negative parenting styles had positive correlations with those variables. In addition, the mediating effects of academic helplessness and social withdrawal in the relationship between parenting styles and depression were confirmed. Finally, there were gender differences in the relationship among parenting styles, depression, academic helplessness, and social withdrawal.
송우근,Suyeon Ahn,Ahreum Kwon,Youngsoo Oh,이상명 한국분자세포생물학회 2023 Molecules and cells Vol.46 No.6
Microtubule acetylation has been proposed as a marker of highly heterogeneous and aggressive triple-negative breast cancer (TNBC). The novel microtubule acetylation inhibitors GM-90257 and GM-90631 (GM compounds) cause TNBC cancer cell death but the underlying mechanisms are currently unknown. In this study, we demonstrated that GM compounds function as anti-TNBC agents through activation of the JNK/AP-1 pathway. RNA-seq and biochemical analyses of GM compound-treated cells revealed that c-Jun N-terminal kinase (JNK) and members of its downstream signaling pathway are potential targets for GM compounds. Mechanistically, JNK activation by GM compounds induced an increase in c-Jun phosphorylation and c-Fos protein levels, thereby activating the activator protein-1 (AP-1) transcription factor. Notably, direct suppression of JNK with a pharmacological inhibitor alleviated Bcl2 reduction and cell death caused by GM compounds. TNBC cell death and mitotic arrest were induced by GM compounds through AP-1 activation in vitro. These results were reproduced in vivo, validating the significance of microtubule acetylation/JNK/AP-1 axis activation in the anti-cancer activity of GM compounds. Moreover, GM compounds significantly attenuated tumor growth, metastasis, and cancer-related death in mice, demonstrating strong potential as therapeutic agents for TNBC.
Association between urinary sodium levels and iodine status in Korea
( Jonghwa Ahn ),( Jang Ho Lee ),( Jiwoo Lee ),( Ji Yeon Baek ),( Eyun Song ),( Hye-seon Oh ),( Mijin Kim ),( Suyeon Park ),( Min Ji Jeon ),( Tae Yong Kim ),( Won Bae Kim ),( Young Kee Shong ),( Won Gu 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.2
Background/Aims: To evaluate the association between the urinary sodium concentration and iodine status in different age groups in Korea. Methods: This nationwide, population-based, cross-sectional study used data from the Korean National Health and Nutrition Examination Survey (VI 2-3, 2014 to 2015). We included 3,645 subjects aged 10 to 75 years with normal kidney function and without a history of thyroid disease. Adequate iodine intake was defined as a urinary iodine/creatinine (I/Cr) ratio of 85 to 220 μg/g. The urinary sodium/ creatinine (Na/Cr) ratios were classified as low (< 47 mmol/g), intermediate (47 to 114 mmol/g), or high (> 114 mmol/g). Results: The median urinary iodine concentration (UIC) was 292 μg/L (interquartile range [IQR], 157 to 672), and the median urinary I/Cr ratio was 195 μg/g (IQR, 104 to 478). Iodine deficiency (< 100 μg/L) and iodine excess (> 300 μg/L) were observed in 11.3% and 49.0% of subjects, respectively. The UIC was significantly associated with the urinary sodium concentration, and the urinary I/Cr ratio was significantly correlated with the urinary Na/Cr ratio (both p < 0.001). The distributions of UIC, urinary I/Cr ratio, and Na/Cr ratio varied among age groups. Low urinary I/Cr and Na/Cr ratios were most common in young adults (age, 19 to 29 years), while high urinary I/Cr and Na/Cr ratios were most common in elderly people (age, 60 to 75 years). Conclusions: Iodine intake was significantly associated with sodium intake in the Korean population. Our study suggested that an adequately low salt intake might be helpful for preventing iodine excess in Korea.