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<SUP>18</SUP>F-FDG PET-CT에서 진단된 갑상선 우연종의 악성종양 발견율 및 특징
이강영,고건<SUP>1<.SUP>,김선국<SUP>1<.SUP>,고진철<SUP>1<.SUP>,김행수,최상용,박신희,박용휘<SUP>2<.SUP>,Kang Young Rhee,Gun Koh,<SUP>1<.SUP>,Sun Kuk Kim,<SUP>1<.SUP>,Jin Chul Koh,<SUP>1<.SUP>,Haeng Soo Kim,Sang Yong Choi,Shin 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.1
<B>Purpose: </B>PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the <SUP>18</SUP>F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV). <B>Methods:</B> <SUP>18</SUP>F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation. <B>Results:</B> The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P<0.001). <B>Conclusion:</B> PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase. <B>(Ko</B><B></B><B>rean J Endocrine Surg 2008;8:38-42)</B>
Intraoperative indocyanine green angiography for the objective measurement of blood flow
Jin Hyun Joh,Ho-Chul Park,Sang-Ah Han,Hyung Joon Ahn 대한외과학회 2016 Annals of Surgical Treatment and Research(ASRT) Vol.90 No.5
Purpose: Intraoperative assessment of tissue perfusion is important to predict wound healing or improvement of symptoms in patients with peripheral arterial disease (PAD) or vascular trauma. There is no widely accepted standard for intraoperative measurement of tissue perfusion. Here, we report the use of indocyanine green (ICG)-based angiography to determine the blood flow in patients with PAD and vascular trauma. Methods: The SPY fluorescent imaging system was utilized. A dose of 3–5 mL of ICG (2.5 mg/mL) was injected intravenously followed by a 10-mL normal saline flush. The SPY imaging system was used to quantitatively assess perfusion. During the study period, the SPY imaging system was applied in 4 patients with PAD and one patient with vascular trauma. Results: In 3 patients with PAD associated with an ischemic wound, complete wound healing was achieved with the indication of viable tissue by the SPY system. In one patient with severe claudication in both lower extremities, the ICG angiography was used to determine the increased blood flow after revascularization. In the case of vascular trauma, this imaging system enabled the delineation of viability of the injured tissue. Conclusion: ICG angiography can determine the surface tissue viability in PAD patients. In cases of severe vascular trauma, the SPY system can be used to determine tissue perfusion. Further study is warranted to define the definite utility of this technology to assess perfusion, response to revascularization, and potentially, to predict the likelihood of wound healing.
Basic : Lactococcus garvieae septicemia with Liver abscess in an immunocompetent patient (초)
( Sang Wook Lee ),( Hyung Joon Kim ),( Suh Yoon Yang ),( Hyun Woong Lee ),( Bong Ki Cha ),( Beom Jin Kim ),( Hyoung Chul Oh ),( Chang Hwan Choi ),( Jeong Wook Kim ),( Jae Hyuk Do ),( Jae Gyu Kim ),( S 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3(S)
Effects of spawning on immune functions in the surf clam Mactra veneriformis (Bivalvia: Mactridae)
( Jin Ha Yu ),( Min Chul Choi ),( Eun Bin Jung ),( Sung Woo Park ) 한국어병학회 2011 한국어병학회지 Vol.24 No.1
The production of surf clam, Mactra veneriformis, an important fishery resource in Korea, has recently been decreasing. This study was carried out to examine effects of spawning on immune functions of this species. Total hemocyte count (THC), phenoloxidase (PO) activity, phagocytic activity, neutral red retention (NRR) time and antibacterial activity were assessed. Spawned clams showed reduction in THC, PO, phagocytic activity and NRR times compared with unspawned ones. While spawning event did not elicit any change of antibacterial activity in both spawned and unspawned ones. This study indicates that spawning process decreases immune functions in the surf clams which could cause mortality increment and yield reduction.
Jin Uk Choi,Shin Hwang,Dong-Hwan Jung,Gil-Chun Park,Chul-Soo Ahn,Ki-Hun Kim,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Sung-Gyu Lee 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.2
Biliary papillomatosis is a rare disease of the biliary tract. In this study, we present a case of a male patient with biliary papillomatosis with malignant change who underwent living donor liver transplantation (LDLT). The 49-year-old man was admitted due to intrahepatic ductal mass, which was finally diagnosed as biliary papillomatosis. It was initially treated by photodynamic therapy, but LDLT was planned due to low efficacy of photodynamic therapy. LDLT was performed with a right liver graft from his son. The pathology report revealed intraductal papillary neoplasm with associated invasive carcinoma. He recovered uneventfully. Although the distal bile duct resection margin was free of tumor, the risk of tumor recurrence at the remnant intrahepatic bile duct still remained. Therefore, staged pylorus-preserving pancreatoduodenectomy was planned. However, after 3 months, he was readmitted due to retropancreatic abscess. It took 6 months to control the intractable retropancreatic abscess. Due to late development of retropancreatic abscess and its slow recovery, staged pancreatoduodenectomy was no longer considered. The patient recovered complete at 1 year posttransplant without any evidence of disease recurrence. After 5 years posttransplant, lung metastasis developed and pulmonary metastasectomy was performed three times. No further recurrence developed during the last 3 years to date, and the patient currently is alive, 10 years after the LDLT. Experience on our case and literature review suggest that patients with biliary papillomatosis with or without malignant transformation are selectively indicated for liver transplantation.
Sang-Chul Kwon,Sunhee Shin,Jeong Hee Jeon,Dongsun Park,Min-Jung Jang,Jwa Jin Kim,Chang Hwan Kim,Jae-Hyun Jeong,Yun-Bae Kim 한국실험동물학회 2008 Laboratory Animal Research Vol.24 No.1
The effects of rose petal extract (RPE) and Ganoderma lucidum culture (GLC) on the systemic and local anaphylactic reactions induced by compound 48/80 were investigated in mice. To induce systemic anaphylactic shock, male ICR mice were intraperitoneally challenged with a lethal dose (8 ㎎/㎏) of compound 48/80, a mast cell degranulator, 30 min after intraperitoneal administration of RPE or GLC (10, 32 or 100 ㎎/㎏). In comparison with 100% death, within 60 min, of control mice administered with vehicle, the mortalities of mice pretreated with 32 and 100 ㎎/㎏ of RPE were decreased to 20 and 0%, respectively. A dose-dependent decrease in the mortality was also achieved with GLC, resulting in 60, 20 and 0% in mice pretreated with 10, 32 and 100 ㎎/㎏, respectively. In local atopic dermatitis induced by intradermal injection of compound 48/80 (50 ㎍/site), the mice exhibited 169.1±10.5 times of scratching behaviors for 30 min and vascular leakage of Evan's blue; 118.3±16.9 mm2 in size and 2.61±0.48 μg in amount. The scratching behaviors induced by compound 48/80 was significantly attenuated by 6-day oral pretreatment with RPE (300 ㎎/㎏) to 86.9±16.4 times. In addition, Evan's blue leakage was also greatly reduced by RPE. In contrast, GLC did not decrease both the number of scratching behaviors and dye leakage, implying that different factors other than histamine are also involved in the atopic dermatitis induced by compound 48/80. Taken together, it is suggested that RPE contains ingredients inhibiting degranulation or action of inflammatory mediators from mast cells, and that could be a promising candidate for the prevention of systemic or local allergic reactions including atopic dermatitis.