http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Sun Taik Chang ) (검색결과 125 건)
- 무료
- 기관 내 무료
- 유료
-
마우스 골수세포의 액체배양에서의 세포화학적 염색성에 관한 연구
김현태,박애자,장선택 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.4
The mouse bone marrow cells were cultured in liquid culture system to investigate the correlation of cytochemical changes and the number of colony forming unit granulocyte/macrophage(CFU-GM) and colony-forming unit megakaryocyte(CFU-Meg) colonies with cell maturation and platelet formation. The following results are obtained; 1. Total colony counts are markedly increased during 4-6 days of culture and reach the maximum number by 7th day (262.33 ± 192.33/ml). The number of cells are increased in each colonies without increase of total colony number after 5 days. 2. The mean ratio of acetylcholinesterase positive megakaryocyte colonies are 13.70 ± 7.04% of total colonies formed with no remarkable changes during 9 days culture period. The number of megakaryocyte colonies reach maximum level by 7th day (31.37 ± 25.73/ml), while that of nonmegakaryocytic colonies reach maximum level by 9th day (230.51 ± 81.90/m1). 3. Platelet count in medium are 5,000 ± 3,490/ml with no remarkable changes during 9 days of culture periods. 4. In acetylcholinesterase positive megakaryocytic colonies, the PAS stain show weak positive in few megakaryocyte by 3rd day, however about 40% of megakaryocytes show rather strong positivity by 7th day. The positivity of non-specific esterase and acid phosphatase are less than 10% until 9th flay of culture. Specific esterase positivity was not found during 9 days period of culture. 5. Non-specific esterase and acid phosphatase stain show lower positivies (11%, 5%) than PAS and specific esterase stain (21%, 55%) in non megakaryocyte colonies. In summary, the number of CFU-GM and CPU-Meg colonies in liquid culture are increased gradually and reached maximum by 7th day, forming large colonies from 5th days on In megakaryocytic colonies, no evidence of platelet formation were observed during 9 days period of culture. It is suggesed that the majority of CFU -GM colonies in liquid culture are mixed colonies according to the cytochemical stainabilities.
-
-
김성택,오창진,홍승관,문명선 대한신경외과학회 1991 Journal of Korean neurosurgical society Vol.20 No.8
The authors retrospectively analyzed the MRI findings of the 8 head-injured patients who had showed persistent unconsciousness and severe neurologic deficite after trauma. T2-weighted MR images disclosed high signal intensity lesions of various size and shape at lobar white matter and corpus callosum, subcortical gray matter, brain stem, and cerebral cortex, and assisted greatly in understanding the neurologic deficits of the corresponding patients. The lesions were mostly multiple and involved multiple structures CT's revealed in those patients only small hemorrhages, suspicious low densities, such nonspecific findings as slit ventricles and diffuse brain atrophy, or no abnormality at all. Post-traumatic parenchymatous lesions detected by MR images were either missed or quite underestimated on CT's. MRI was very superior to CT in the detection and anatomic localization of nonhemorrhagic intraaxial cerebral injuries, especially in the cases of small cortical contusions. CT is indicated in order to fastly detect intracranial hematomas which may need emergent surgical evacuation. If CT findings does not explain the neurologic degicits of the patients, especially in the late stage. MRI is indicated, MRI is expected to play a major role in the diagnosis of shear injuries involving white matter and brainstem where CT has been of little contribution or misleading.
-
-
5-Fluorouracil 투여가 마우스공장 소낭선세포의 방사선조사 효과에 미치는 영향
허승재,박찬일,장선택 중앙대학교 의과대학 의과학연구소 1985 中央醫大誌 Vol.10 No.3
The interaction of radiation and 5-Fluorouracil(5-FU) on mouse jejunal crypt cells was studied using the microcolony survival assay. 150㎎/㎏ of 5-FU was injected intraperitoneally 15 minutes before irradiation and 6 hours after irradiation. Jejunal crypt cells of mouse survived more when 5-FU was given 15 minutes before irradiation than giving it 6 hours after irradiation. The mean lethal doses(Do) of each of irradiation alone group, 5-FU injection group of 15 minutes preceding irradiation, and 5-FU injection group of 6 hours postirradiation were, 135, 135, and 114 rad respectively. The dose effect factor of each of 5-FU injection groups of 15 minutes preceding irradiation and of 6 hours post irradiation were 1.13 and 1.27.
-
백서 대장암의 동종면역효과에 관한 연구 : Effect of Cancer Bearing Rat Serum
김형일,박애자,장선택 중앙대학교 의과대학 의과학연구소 1988 中央醫大誌 Vol.13 No.2
In recent years, there has been much interests in identification and characterization of numerous tumor relating substances including ectopic hormones, oncofetal antigens, or abnormal enzymes for the diagnosis and monitoring of malignant tumors. But, practically so called cancer antigen, such as AFP, CEA, or TPA, which has been never used toward manufacturing anti-cancer antibody, while only used to compete the cancer tissue type specificity. Nowadays, cancer antigen must be actually applied in the field of cancer treatment by means of the mediator or inducer for anti-cancer antibody formation. This study researched the alloimmunization effect of the serum components obtained from cancer developing animals, chemical carcinogen (NG: N-methyl-N'-nitroso-N-nitrosoguanidine) induced colon adenocarcinoma model, in 216 male rats, and gained following results: 1. In cancer producing rats, the CRP levels were maintained evenly high values althrough the experimental period, but serum TPA was gradually increased along sequential studies, while βCG and LDH were increased in early acute phase and sooner decreased in late phase. 2. The individuals, those were alloimmunized by the serum acquired from cancer bearing rats, represented significantly high cancer rejection rate, especially in the group which was infused the serum of conspicuously high TPA concentration. 3. In the long survivers and cancer resistance group, could observed neither high βCG level nor increased LDH value, however the early deaths revealed extremely higher βCG and LDH levels in contrast of relatively lower TPA concentration. 4. So, there was able to confirm the fact that not only cancer rejection antigenicity was presented in the serum of cancer developing individuals, but also could gained prominent allommunization effect utilizing such serum of high occurring TPA believing one of immunologic cancer rejectives by itself or mediation of antibody inducing effects.
-
최영규,장선택 중앙대학교 의과대학 의과학연구소 1987 中央醫大誌 Vol.12 No.1
The hemodynamic alterations were measured similtaneously by both invasive and non-invasive method in Korean mongrel dogs following the induction of acute myocardial ischemia by ligation of left coronary artery. By non-invasive method, the systolic time intervals were determined by similtaneous recordings of electrocardiogram, phonocardiogram and carotid arterial pulse tracing. By invasive method , direct measurements were made on heart rate, blood pressure, central venous pressure, pulmonary capollary wedge pressure and cardiac output. The results obtained by invasive and non-invasive STI method were as follows. 1. Among the hemodynamic changes measured by the invasive method, a marked elevation in PCWP(p<0.01) was observed at 30 minutes after the ligation of the coronary artery however no significant change was noted with other parameters. 2. There were no significant changes among STI parameters occuring acute myocardial ischemia and their parttens were similar to invasive measuring. 3. Comparing the data of invasive method with those of noninvasive STI method, the linear relationships were found. The correlation coefficient of CPP to dBP was 0.96, that of TI to PCWP, 0.91, and that of EVR to dT/sT,0.78. Analysis of data on the hemodynamic changes obtained by invasive and non-invasive STI methods confirmed the possibility that the non-invasive method may replace the invasive one for monitoring the hemodynamic changes in clinical management of acute myocardial ischemia.
-
-
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
