과학기술계산을 위한 전자계산기용 특수 Library 개발에 관한 연구

金相萬,姜承業,沈在洪,文東纘,徐光烈,洪勝弘,愼哲宰 광운대학교 1972 論文集 Vol.2 No.-

In this paper the subroutine library of digital computer techniques to the solution of electronic networks problem are discussed. The application of digital-computer techniques to the solution of the integrations relating the terminal variables for linear time invariant inductos and capaciters are analyzed, then on the techniques of numerical integrations trapezoidal method is used. The subroutine library for differential equations and determinations which are used in electronic networks analysis have been developed. Since these programs are the general form, anybody can utilize the programs for his own purpose.

흰쥐에서 외상성 신경종예방에 대한 연구

김승한,전종완,강진성,김찬환,정재홍 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.5

Prevention of traumatic neuroma has been the subject of extensive since early in the nineteenth century. Odier described this enlargement which develops at the distal end of proximal segments of peripheral nerves after partial or complete transsection. However, there seems to be no unanimity of opinion regarding the treatments of nerve at the time of severed injury. Ligating the proximal end of such a nerve, implanting it into muscle or born, resecting it, injecting it with a sclerosing agent or capping it with a silicone cuff are commonly used at the present time. Petropoulos introduced a nitrogen mustard as a sclerosing agent to prevent the neuroma. Tupper and Booth reported funniculecomy and epincurial ligation with satisfactory result obtained in many patients. However there is no commonly acceptable method. The authers carried out animal studys to find out the better operative procedure to prevent the traumatic neuroma. The sciatic nerve of the rat was exposed under the operating microscope and resected about 1㎝ from the end of the divied portion. Eighty rats were divided into 4 groups by a technique to differentiate management of the severed proximal nerve ends, that is, a control group, a nitrogen mustard injected group, a epineurial ligation group and a combined group(epineurial ligation following the injection of nitrogen mustard). The wound was closed with 4-0 black silk. Three months later, the wound was reopened and the presence of neuroma was observed grossly and microscopically. The results were as follows : 1) The proximal portion of the severed nerve in the combined group were tapered to the end and neuromas were hardly seen grossly. 2) The diameters of minifascicle and the numbers of nerve fibers of the combined group were the smallest and fewest compared with others(p<0.05). 3) The combined group took only 2 to 3 minutes more than the others, but it was better method. The authors found the superiority of this latter method, epineurial ligation following nitrogen mustard injection in the severed end, compaired with the others.

현역군인 발생을 중심으로 본 2001년도 국내 삼일열 말라리아 발생 현황

류승호,이원자,김영아,채종일,박재원 대한감염학회 2002 감염 Vol.34 No.5

L-N-Benzylaspartic acid의 선택적 에스테르화 반응

이채호,김일광,박승화,이영행,정봉영 圓光大學校 基礎自然科學硏究所 1987 基礎科學硏究誌 Vol.6 No.1

Selective esterification and synthesis of L-N-benzylaspartic acid from L-aspartic acid are described. L-Aspartic acid was transformed into dibenzyl L-asparate p-toluenesulfonate, which was treated with sodium bicarbonate to afford dibenazyl L-asparate. Formation of Schiff base of dibenayl ester with benzaldehyde and subsequent hydrogenation-dehydrogenation of the Schiff base produced L-N-benaylaspartic acid. L-N-Benaylaspartic adcid was transformed into L-N-benzylaspartic anhydride hydrogen bromide, which was treated with methyl alcohol and benzyl alcohol to afford a-methyl and a-benzyl L-N-benzylaspartate and L-N-benaylaspartic acid was transformed into L-N-benaylaspartic acid copper(Ⅱ) salt, which was treated with N,N,N,N-tetramethylguanidine and benzyl bromide to afford β-benzylaspartate

자궁경부의 상피내암 조직내 In Situ Hybridization에 의한 Human Papillomavirus DNA의 검색 및 Typing

이상숙,김기권,정재홍,김택훈,이태성,진승원,손우익 대한의학협회 1990 대한의학협회지 Vol.33 No.1

성공적인 eCRM, CRM을 위한 유전자알고리즘의 혼합 초기화법을 이용한 데이터마이닝

강래구,김승언,정채영 朝鮮大學校 統計硏究所 2006 統計硏究所論文誌 Vol.8 No.1

고객관리가 기업의 성패를 좌우하는 중요한 화두로 떠오르면서 보다 쉽고 편리하게 고객의 다양한 Pattern을 발견하고 예측하기 위해 많은 기업들이 CRM과 eCRM을 빠르게 도입하고 있다. 과거엔 고객관리가 통계학자들이나 전문적인 통계패키지에 의해 관리되어 왔으나 IT 분야의 급격한 발달을 기반으로 통계적 과정을 자동화시킨 Data Mining 기법으로 점점 대체되고 있는 추세이다. 이러한 Data Mining이 대표적으로 이용되고 있는 분야가 CRM, eCRM이다. Genetic Algorithm을 이용하여 Data Mining을 적용함에 있어서 본 논문에서는 무작위 초기화법과 유도된 초기화법을 동시에 사용하는 새로운 집단 초기화 방법을 적용하여 A할인점의 2004년과 2005년도 우수고객을 예측하였고 실제 고객 데이터와의 비교를 통해 본 논문에서 제안한 새로운 집단 초기화 방법의 성능을 입증하였다.

슬러지 재자원화에 관한 연구

이주성,공성호,서승원,배성렬,김영채,이기철 漢陽大學校 環境工學硏究所 1997 環境科學論文集 Vol.18 No.-

이 연구는 1993년도에 우리나라의 연간 슬러지발생량이 약 3500만m³에 이르고 있으며, 이들 대부분이 매립되고 있다. 그러나 매립부지의 확보가 점점 어려워 지고 있으며 아울러 매립처분비용도 상승하고 있기 때문에 oil화, 퇴비화등으로 재자원화 하는 방법과 소각후의 소각회를 유효이용하는 방법 등이 연구 개발되고 실용화되고 있다. 슬러지의 oil화는 현재 연구단계에 있으나 앞으로 슬러지의 유효이용기술로서, 가장 좋은 방법이 되리라 기대되고 있다. 그러나 소각후의 소각회의 이용방법은 현재 일본등에서는 실용화 되어 건설자재 등으로 다양하게 이용하고 있다. 우리나라에서도 서울시 등을 비롯한 대도시에서는 하수처리장에서 발생하는 슬러지를 소각한 후에 소각회를 건설 자제용으로서 지자체의 공사에는 반드시 사용하도록 하는 제도를 만든다면 유효이용방법으로 충분한 타당성이 있을 것이다. 이때 소각방법으로는 용융소각방법이 보다 효과적일 것이다. With increasing sewage and wastewater sludge, it has become difficult to dispose the sludge by landfilling and ocean dumping. To solve this problem, efforts have been made to delelop sewage and wastewater sludge utilization technologies in many advanced countries. Some technologies have already been developed; conversion of sludge to compost and fuel, producing artificial light-weight aggregate from ashes. This paper describes the technical status of sludge utilization technologies.

β-Fluoro-α-phenylpyrrole 유도체의 합성에 관한 연구

郭炅喆,吳賢哲,鄭悳商,李英行,白承和,金鍾洙,蔡奎允 濟州大學校 基礎科學硏究所 2001 基礎科學硏究 Vol.14 No.2

플루오르가 선택적으로 치환된 유기화합물은 모체 화합물 보다 향상된 생리활성을 지니는 경우가 많이 보고 된바 있다. 이는 할로젠족 원소인 플루오르의 큰 전기음성도 때문에 비교적 강한 탄소플루오르 결합 형성 및 증가된 리피드 용해도 때문이다. Pyrrole과 그의 유도체들은 폴리머, 의약품 그리고 염료 등에 광범위하게 사용되어 왔고 오래 전부터 잘 알려진 화합물이다. 최근 자연계에서 산출되거나 합성 가능한 플루오르가 선택적으로 치환된 fluoropyrrole 유도체들은 진통제, 소염제 및 살균제 등으로 다양하게 이용될 수 있음이 알려져 있기 때문에 fluoropyrrole 유도체의 합성에 대한 연구가 활발히 진행되고 있다. 일반적으로 플루오르는 반응성이 매우 커서 유기화합물에 대한 선택적인 플루오르기의 도입이 극히 제한적이다.

Association of Acute Myocardial Infarction with Ossification of the Posterior Longitudinal Ligament in Korea: A Nationwide Longitudinal Cohort Study

Kim Jaehwan,Kim Chai Yoon,Kim Jeong Gyun,Kim Hakyung,Sheen Seung Hun,Han In-bo,Sohn Seil 대한말초신경학회 2023 The Nerve Vol.9 No.1

Objective: This nationally matched longitudinal study aimed to investigate the relationship between acute myocardial infarction (AMI) and ossification of the posterior longitudinal ligament (OPLL) in Korea.Methods: We collected patient data from January 1, 2004 to December 31, 2015 from the National Health Insurance Service Health Screening Cohort. Patients with OPLL were defined as patients with the International Classification of Diseases, Tenth Revision code M48.8 (other specified spondylopathies) and were newly diagnosed through computed tomography imaging. The OPLL group had a total of 1,289 patients. The control group included 6,445 people. Utilizing the Kaplan-Meier technique, The incidence of AMI in both groups was estimated. A Cox proportional-hazards regression analysis was used to compute the AMI hazard ratio.Results: After controlling for age and sex, the hazard ratio of AMI in the OPLL group was 2.065 (95% confidence interval [CI], 1.228-3.474). The adjusted hazard ratio in the OPLL group was 2.209 after restricting the sample for demographics and concomitant medical conditions (95% CI, 1.311-3.721). In a subgroup analysis, the incidence of AMI was substantially greater in the OPLL group, which included women younger than 65 years and without hypertension, diabetes, or dyslipidemia.Conclusion: This nationwide longitudinal study found that patients with OPLL were at higher risk of AMI.

Genomic Polymorphism Analysis using Microsatellite Markers in Gyeongju Donggyeong Dogs

Kim, Seung-Chang,Kim, Lee-Kyung,Choi, Seog-Kyu,Park, Chang-Min,Park, Sun-Ae,Cho, Yong-Min,Lim, Dajeong,Chai, Han-Ha,Lee, Seung-Hwan,Lee, Ji-Woong,Sun, Sang-Soo,Choi, Bong-Hwan The Korean Society of Animal Reproduction 2012 Reproductive & developmental biology Vol.36 No.4

This study was conducted to find a useful marker for gene polymorphism analysis using Microsatellite marker (MS marker) in Gyeongju Donggyeong dog. Twenty three MS marker analyzed the genetic features of DNA using 100 Gyeongju Donggyeong dogs in Gyeongju area. It was performed multiplex PCR with 3 set primer divided 9, 10 and 4 by analysis of conditions among MS markers. The results were calculated heterozygosity, polymorphic information content (PIC), allele frequency and number of allele at each locus using Microsatellite Toolkit software and Cervus 3.0 program. Total 148 alleles were genotyped to determine and average 6.43 alleles was detected. FH3381 had the highest of 15 alleles and FH2834 had the lowest of 2 alleles. Expected heterozygosity had a wide range from 0.282 to 0.876 and had average value of 0.6496. Also, Observed heterozygosity had a more wide range from 0.200 to 0.950 and had average value of 0.6404. PIC had range from 0.262 to 0.859 and average PIC was calculated 0.606. Especially, FH2998 represented the highest rate of observed heterozygosity of 0.950 and FH3381 represented the highest rate of expected heterozygosity of 0.876 and PIC of 0.859. The use of these markers was considered to be useful to study genetic traits of Gyeongju Donggyeong dog.