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      • KCI등재

        Combining Timber Production and Wood Processing for Increasing Forestry Income: A Case Study of 6th Industrialization in Korean Forestry

        Won, Hyun Kyu,Jeon, Hyon Sun,Han, Hee,Lee, Seung Jung,Jung, Byung Heon Institute of Forest Science 2017 Journal of Forest Science Vol.33 No.4

        This study was aimed to analyze the increased forestry incomes by combining timber production and wood processing, which is one of 6th industrialization types in Korean forestry. The selected household has been engaged in forestry for two generations and they produce timber and associated wood products in their own facility. The wood products include dimension lumber, interior wood material, cutting board, and cube chips, the household also utilize logging and sawmill residues as well as seed and seedlings as by-products. Incomes and expenses that have been incurred on individual processes of the sequential timber production and wood processing were surveyed, and we analyzed the economic outcomes of entire business. The results of this study indicate that the gross income of the household is 122.3 million Korean won and the net income is 93.6 million Korean won. The net income of the household is approximately 2.8 times higher than the average net income of whole households in the forestry of Korea in 2016, which is approximately 4.3 times higher than that of households that have been particularly engaged in timber production over the country. We found that the 6th industrialization by combining the two sequential processes creates approximately 3.2 times as much added value compared to the case relying on timber production only.

      • KCI등재

        Combining Timber Production and Wood Processing for Increasing Forestry Income : A Case Study of 6th Industrialization in Korean Forestry

        Hyun Kyu Won,Hyon Sun Jeon,Hee Han,Seung Jung Lee,Byung Heon Jung 강원대학교 산림과학연구소 2017 Journal of Forest Science Vol.33 No.4

        This study was aimed to analyze the increased forestry incomes by combining timber production and wood processing, which is one of 6th industrialization types in Korean forestry. The selected household has been engaged in forestry for two generations and they produce timber and associated wood products in their own facility. The wood products include dimension lumber, interior wood material, cutting board, and cube chips, the household also utilize logging and sawmill residues as well as seed and seedlings as by-products. Incomes and expenses that have been incurred on individual processes of the sequential timber production and wood processing were surveyed, and we analyzed the economic outcomes of entire business. The results of this study indicate that the gross income of the household is 122.3 million Korean won and the net income is 93.6 million Korean won. The net income of the household is approximately 2.8 times higher than the average net income of whole households in the forestry of Korea in 2016, which is approximately 4.3 times higher than that of households that have been particularly engaged in timber production over the country. We found that the 6th industrialization by combining the two sequential processes creates approximately 3.2 times as much added value compared to the case relying on timber production only.

      • KCI등재
      • KCI등재

        Disk Diffusion Susceptibility Testing for the Rapid Detection of Fluconazole Resistance in Candida Isolates

        Jeon Suhak,Shin Jong Hee,Lim Ha Jin,Choi Min Ji,Byun Seung A,Lee Dain,Lee Seung Yeob,Won Eun Jeong,Kim Soo Hyun,Shin Myung Geun 대한진단검사의학회 2021 Annals of Laboratory Medicine Vol.41 No.6

        Background: Given the increased fluconazole resistance (FR) among Candida isolates, we assessed the suitability of disk diffusion susceptibility testing (DDT) for the early detection of FR using well-characterized Candida isolates. Methods: In total, 188 Candida isolates, including 66 C. albicans (seven Erg11 mutants), 69 C. glabrata (33 Pdr1 mutants), 29 C. parapsilosis (15 Erg11 mutants), and 24 C. tropicalis (eight Erg11 mutants) isolates, were tested in this study. FR was assessed using DDT according to the standard CLSI M44-ED3 method, except that two cell suspensions, McFarland 0.5 (standard inoculum) and 2.5 (large inoculum), were used, and the inhibition zones were read at 2-hour intervals from 10 hours to 24 hours. Results: DDT results for the standard inoculum were readable after 14 hours (C. albicans, C. glabrata, and C. tropicalis) and 20 hours (C. parapsilosis) for >95% of the isolates, whereas the results for the large inoculum were readable after 12 hours (C. glabrata and C. tropicalis), 14 hours (C. albicans), and 16 hours (C. parapsilosis) for >95% of the isolates. Compared with the results produced using the CLSI M27-ED4 broth microdilution method, the first readable results from the DDT method for each isolate exhibited an agreement of 97.0%, 98.6%, 72.4%, and 91.7% for the standard inoculum and 100%, 98.6%, 96.6%, and 95.8% for the large inoculum for C. albicans, C. glabrata, C. parapsilosis, and C. tropicalis, respectively. Conclusions: DDT using large inoculum may detect FR rapidly and reliably in the four most common Candida species.

      • KCI등재

        Role of Dedicated Subspecialized Radiologists in Multidisciplinary Team Discussions on Lower Gastrointestinal Tract Cancers

        Jeon Sun Kyung,Kim Se Hyung,Shin Cheong-Il,Yoo Jeongin,Park Kyu Joo,Ryoo Seung-Bum,Park Ji Won,Kim Tae-You,Han Sae-Won,Lee Dae-Won,Chie Eui Kyu,Kang Hyun-Cheol 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.7

        Objective: To determine the impact of dedicated subspecialized radiologists in multidisciplinary team (MDT) discussions on the management of lower gastrointestinal (GI) tract malignancies. Materials and Methods: We retrospectively analyzed the data of 244 patients (mean age ± standard deviation, 61.7 ± 11.9 years) referred to MDT discussions 249 times (i.e., 249 cases, as five patients were discussed twice for different issues) for lower GI tract malignancy including colorectal cancer, small bowel cancer, GI stromal tumor, and GI neuroendocrine tumor between April 2018 and June 2021 in a prospective database. Before the MDT discussions, dedicated GI radiologists reviewed all imaging studies again besides routine clinical reading. The referring clinician’s initial diagnosis, initial treatment plan, change in radiologic interpretation compared with the initial radiology report, and the MDT’s consensus recommendations for treatment were collected and compared. Factors associated with changes in treatment plans and the implementation of MDT decisions were analyzed. Results: Of the 249 cases, radiologic interpretation was changed in 73 cases (29.3%) after a review by dedicated GI radiologists, with 78.1% (57/73) resulting in changes in the treatment plan. The treatment plan was changed in 92 cases (36.9%), and the rate of change in the treatment plan was significantly higher in cases with changes in radiologic interpretation than in those without (78.1% [57/73] vs. 19.9% [35/176], p < 0.001). Follow-up records of patients showed that 91.2% (227/249) of MDT recommendations for treatment were implemented. Multiple logistic regression analysis revealed that the nonsurgical approach (vs. surgical approach) decided through MDT discussion was a significant factor for patients being managed differently than the MDT recommendations (odds ratio, 4.48; p = 0.017). Conclusion: MDT discussion involving additional review of radiology examinations by dedicated GI radiologists resulted in a change in the treatment plan in 36.9% of cases. Changes in treatment plans were significantly associated with changes in radiologic interpretation.

      • Reverse signaling through BAFF differentially regulates the expression of inflammatory mediators and cytoskeletal movements in THP‐1 cells

        Jeon, Sung‐,Tak,Kim, Won,Jung,Lee, Sang‐,Min,Lee, Min‐,Young,Park, Seung,Beom,Lee, Seung,Hee,Kim, In‐,San,Suk, Kyoungho,Choi, Beom Kyu,Choi, Eun M,Kwon, By Nature Publishing Group 2010 Immunology and Cell Biology Vol.88 No.2

        <P>Most members of the tumor‐necrosis factor superfamily have been reported to mediate reverse signaling in T cells, macrophages, and/or dendritic cells. BAFF has been reported to have important functions in B‐cell survival through forward signaling, but the presence of reverse signaling has not been explored. To investigate the possibility of BAFF‐mediated reverse signaling, the expression patterns and functions of BAFF were analyzed in monocytic cell lines including the human macrophage‐like cell line, THP‐1. The expression of BAFF and its receptors was detected in monocytic cell lines, either before or after activation. The stimulation of BAFF induced the expression of matrix metalloproteinase (MMP)‐9, interleukin ‐8, and transforming growth factor‐β‐induced gene product (βig‐h3) and the upregulation of intercellular adhesion molecule‐1 in THP‐1 cells. The activation of mitogen‐activated protein kinase extracellular signal‐regulated kinase1/2 and nuclear factor‐κB was required for these responses. In addition to these stimulatory effects, BAFF‐mediated signaling inhibited processes involving cytoskeletal movement such as phagocytosis and transmigration through blocking the activation of phosphatidylinositol 3‐kinase/AKT and Rac‐1. Furthermore, murine primary macrophage culture such as peritoneal macrophages expressed BAFF and stimulation of it induced the expression of MMP‐9. These observations show that the reverse signaling initiated from BAFF induces the expression of inflammatory mediators while suppressing the cytoskeletal movements associated with phagocytosis and transmigration.</P>

      • Evaluation of the prognostic significances of γ-secretase genes in pancreatic cancer

        Jeon, Yun Ho,Ha, Mihyang,Kim, Sung Won,Kim, Mun Ju,Lee, Chi-Seung,Oh, Chang-Kyu,Han, Myoung-Eun,Oh, Sae-Ock,Kim, Yun Hak D.A. Spandidos 2019 Oncology letters Vol.17 No.5

        <P>With the growing requirement for novel prognostic biomarkers for pancreatic cancer, many studies have focused on clinical and/or genomic variables. Although many studies have been performed, carbohydrate antigen 19-9 is the only biomarker in clinical use. Therefore, the present study examined whether γ-secretase genes, including presenilin (<I>PSEN</I>), nicastrin (<I>NCSTN</I>), presenilin enhancer protein 2 (<I>PSENEN</I>), and anterior pharynx-defective 1 (<I>APH1</I>-), could serve as prognostic factors for pancreatic cancer. The cohorts selected included >100 pancreatic cancer patients. Patient data were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GSE21501). The prognostic roles of the γ-secretase genes were analyzed by several survival analysis methods. Among the γ-secretase genes, the prognosis tended to be worse in the 2 cohorts with increasing expression of <I>PSEN1, APH1A</I>, and <I>PSENEN</I>, while the remaining genes were the opposite in the 2 cohorts. Notably, although the patient characteristics were quite different, <I>APH1A</I> was statistically significantly associated with prognosis in the 2 cohorts. The hazard ratio of <I>APH1A</I> for overall survival was 1.598 (TCGA) and 2.724 (GSE21501). These results contribute to the study of γ-secretase in pancreatic cancer. We believe that γ-secretase, particularly <I>APH1A</I>, will be a new prognostic biomarker for pancreatic cancer.</P>

      • SCISCIESCOPUS

        Electronically modified Pd catalysts supported on N-doped carbon for the dehydrogenation of formic acid

        Jeon, Mina,Han, Da Jung,Lee, Kug-Seung,Choi, Sun Hee,Han, Jonghee,Nam, Suk Woo,Jang, Seong Chul,Park, Hyun S.,Yoon, Chang Won Elsevier 2016 International journal of hydrogen energy Vol.41 No.34

        <P><B>Abstract</B></P> <P>In this study, an electronically modified Pd nanocatalyst supported on nitrogen-doped carbon (<B>Pd/N–C</B>) was synthesized by a facile, scalable synthetic method. The electronic interaction between the nitrogen atoms incorporated into the carbon support and Pd active sites, as evidenced by X-ray photoelectron spectroscopy (XPS), resulted in the formation of electron-rich Pd sites. The resulting Pd catalyst demonstrated enhancement in catalytic activity for the dehydrogenation of formic acid via the activation of C–H bonds in H–COOH. Finally, a hydrogen generation system fueled by formic acid was designed and further integrated with a polymer electrolyte membrane fuel cell (PEMFC) stack for the successful demonstration of stable, practical production of hydrogen, generating a fuel cell power of 180 W over 1 h without noticeable catalytic deactivation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Efficient formic acid (FA) dehydrogenation is demonstrated using Pd nanocrystals. </LI> <LI> Electronically modified <B>Pd/N–C</B> catalysts are synthesized by a scalable method. </LI> <LI> Nitrogen atoms doped to carbon enhance the metal-support interactions of Pd/N-C. </LI> <LI> FA dehydrogenation system is employed to power a 200 W PEMFC over 1 h. </LI> </UL> </P>

      • Drug-Enhanced Unclogging Motions of a Double Helical Magnetic Micromachine for Occlusive Vascular Diseases

        Seung Mun Jeon,Gun Hee Jang,Won Seo Lee IEEE 2014 IEEE transactions on magnetics Vol.50 No.11

        <P>We propose a novel double helical magnetic micromachine (DHMM) to achieve drug-enhanced unclogging abilities for occlusive vascular diseases (OVDs) in human blood vessels. The proposed DHMM can generate navigating and mechanical drilling motions actuated by an external rotating magnetic field (ERMF). It can also deliver a clot-busting drug to a target point (clogged area) and can precisely release the drug toward the clogged area. We derive rotational dynamic constraint equations for selective manipulation of the navigating, drug releasing, and mechanical drilling motions of the DHMM by controlling the ERMF. We then prototype the DHMM and demonstrate these motions to show the validity of the proposed DHMM and manipulation methods.</P>

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