Bilateral Scalp Flap을 利用한 대머리 矯正手術 : -1例 報告- -Report of One Case-

薛正泫 大韓成形外科學會 1979 Archives of Plastic Surgery Vol.6 No.1

The male pattern baldness is a sex-linked dominant gene is responsible for varying degrees of baldness in over 80% of males. Many accept this fact gracefully, while increasing numbers desire treatment for the psychological or simple cosmetic problems associated with baldness. The techniques for correction of male pattern baldness are punch graft, strip graft and local scalp flaps etc, but the scalp flaps is instant good hair density along the anterior hair line. Recently, I was experienced a simplified technique for transposing undelayed bilateral temporal scalp flaps and it is presented here. The use of short, narrow flaps obviates the need for delay procedures, it permits easier closure of the donor sites and got relatively satisfactory result.

Triamcinolone Acetonide가 배양 켈로이드 섬유아세포의 G1 세포주기 관련 유전자 발현에 미치는 영향

설정현,우상현,백원기,서성일,서민호 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.2

The effect of triamcinolone acetonide(TA) on the expression of Gl related genes was investigated the cultured keloid fibroblast. The addition of TA to the culture medium resulted in growth inhibition of keloid fibroblast. TA reduced the expression of cyclin A, B, E and cyclin dependent kinase(CDK) 2 mRNA, but unexpectedly, the expression of cyclin C, Dl and CDK4 mRAN was not affected significantly as compared with those of normal fibroblast. Expressions of p16, p21 and p27, the wellestabilished CDK-inhibitors, were also investigated. The level of p16 was not detected in both normal and keloid fibroblasts and the expression of p27 was significantly decreased in keloid fibroblast. The expression of p21 was dramatically increased in keloid fibroblast but not significantly changed in normal fibroblast. Also the expressions of p53 and pRb, the well known tumor suppressor genes, were increased by the addition of TA. These data suggested that the observed growth inhibitory effect of TA may be related to transcriptional inactivation of cyclin A, B, E and CDK2 and to the transcriptional activation of p21, but the mechanisms of unchanged expression of cyclin C, Dl and CDK4 mRNA remain to be elucidated.

Lower Blepharoplasty時 Skin Flap法과 Muscle Flap法의 比較觀察

薛正泫 大韓成形外科學會 1982 Archives of Plastic Surgery Vol.9 No.2

Aesthetic fewer blepharoplasty is performed to correct deformities of wrinkles, hypertiophy of orbicularis oculi muscle and protrusion of orbital fat in lower eyelids. Today, blepharoplasty has become a commonplace operation by many plastic surgeon, and a number of operative techniques for the procedure has been described, but no one technique is suitable for all patients. The author used two different procedure as skin flap method and muscle flap method according to case by case. The muscle flap method is indicated in young patients with protruding orbital fat and hypertrophy of the orbicularis oculi muscle with marked excess skin, and less ecchymosis and swelling in post operative period compare to skin flap method.

각종 골대체물질들의 골형성능에 관한 비교연구

설정현,최원희,김정철,홍정수,서동보 大韓成形外科學會 1992 Archives of Plastic Surgery Vol.19 No.4

We studied the bone forming capacity of the various bone substitute materials for the confirmation of bone regeneration with each case i.e Hydroxyapatite(SURGIBON), kiel obne, B.O.P. and bone dust. The bone dust was used for control. In 18 New Zealand white rabbits, four partial thickness bone defects were created on the outer table of parietal bone, which were measured 1.5mm in depth x 8mm in diameter. Bone substitute materials were filled in each bone defect. The animals were sacrified at 2, 4, 6, 8 weeks after taking a plain skull film, and then both macroscopic and microscopic examinations were done. The results were as follows : 1. Hydroxyapatite : good bone regeneration with moderately increased eosinophil. 2. KIEL BONE : no bone regeneration and markedly increased eosinophil. 3. B.O.P. : no evidence of bone growth during postoperative 8 weeks. 4. BONE DUST : persistent osteoblast existed during experimental period, more likely as own bone. We summarized that the hydroxyapatite is a biocompatible matrix implantable as a bone graft substitute and more bone regeneration than other bone substitutes during the experimental period.

皮膚移植후 壓迫處置를 위한 Resin Mold의 利用

薛正泫 대한성형외과학회 1981 Archives of Plastic Surgery Vol.8 No.1

The Use of pressure therapy has been sucessfully employed as a prophylactic measure to prevent the development of hypertrophic scar and secon-dary wound contraction. We has been employed the pressure bandage, cast splint, jacket and dynamic splint but on the face surgery such as hemangioma and nevus etc is very difficult in fixation and it's management. Recently, I was used the Resin mold on the face for pressure therapy and got relatively satisfectory result.

배관내에서 난류 마찰 저항감소에 관한 연구

박설현,윤정환,서동표,정대훈,오율권 朝鮮大學校 機械技術硏究所 2000 機械技術硏究 Vol.3 No.1

Polymer drag reduction can offer a attractive way to utilize ready-made facilities in crude-oil transport system without additional large expenditure. Also, drag reduction in two phase flow can be applied to phase change system such as chemical reactor, pool and pump impeller which occurs cavitation. But the research on drag reduction in two phase flow has not been investigated. Therefore, experimental investigations have been carried out to analyze the drag reduction in the single phase and two phase flow. The objectives of the proposed investigation are primarily to identify and develop high performance polymer additives for fluid transportation. And drag reduction will be evaluated in horizontal flow by measuring void fraction, pressure drop, mean liquid velocity and turbulent intensity

초음파 진동이 가진된 밀폐용기에서 상변화 열전달 특성

박설현,정대훈,오율권 조선대학교 에너지.자원신기술연구소 2001 에너지·자원신기술연구소 논문지 Vol.23 No.1

Solid-liquid phase change (i.e. melting or solidification) occurs in a number of situations of practical interest. Some common examples include the melting of edible oil. metallurgical process such as casting and welding, and materials science applications such as crystal growth. Therefore, due to the practical importance of the subject, there have been a large number of experimental and numerical studies of problems involving phase change during the past few decades. This study presents experimental work on phase change heat transfer. Especially, in order to increase heat transfer rate. ultrasonic vibrations were introduced. The melting cavity contained one vertical heating surface which dissipates heat at constant power and was insulated on the sides. Experimental observations show that the effect of ultrasonic vibrations on heat transfer is very important throughout melting process. The results of this study reveal that ultrasonic vibrations accompany the effects like agitation, acoustic streaming, cavitation, and oscillating fluid motion. Such effects are a prime mechanism in the overall melting process when ultrasonic vibrations are applied. They speed up the melting process as much as 2.5 times, compared with the result of natural melting. Also, energy can be saved by applying ultrasonic vibrations to the natural melting.

가토의 하악골 연장시 Sodium fluoride 투여가 골형성에 미치는 영향

김용하,설정현,변우목,김정철,우상현,강무석 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.4

The purpose of this study was to improve bone formation and shorten the period involved in distraction osteogenesis using sodium fluoride (NaF). This has been used in managing osteoporosis for several decades. This study was carried out on 40 New Zealand white rabbits. Twenty animals were used for a control group (no medication) and 20 for the experimental group. NaF 1 mg/kg/day was administered to each experimental animal via drinking water beginning 4 weeks prior to surgery and continued until sacrifice for examination. A distraction device was applied to the left mandible along a plane perpendicular to the direction of osteotomy. After a 5-day latent period, the mandibles were lengthened at 1 mm per 24 hours for 10 days. Five rabbits from each group were sacrificed on the 1st day, 2nd week, 4th week and 8th week of the consolidation period. After lengthening, all the rabbits developed a severe cross-bite. By the 4th week, cortical continuity was seen. Bone densities at the site of bony lengthening were measured by quantitative computer tomography (QCT) and dual X-ray absorptiometry (DXA). The results were as follows: the measurements of the experimental group were significantly higher than of the control group by the 1st day of the consolidation period (p<0.05) and insignificantly higher after the 2nd week. Histologically, in the experimental group, there were more osteoblasts, increased and thickened trabeculae and more mature lamellar bones than in the control group. This study showed that osteogenesis of the experimental group was significantly higher during and immediately after distraction. Our study suggested that the use of NaF could improve bone formation and decrease the period of distraction osteogenesis if a safe dose and method of fluoride administration can be determined for growing humans.

가토의 하악골 연장에서 잠복기간 단축의 영향

김용하,설정현,최준혁,강무석 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.5

To evaluate the effect of shortening the latent period for distraction osteogenesis, the authors experimented with distraction osteogenesis for a 24-hour latent period in the mandibles of rabbits. This study was carried out on 32 New Zealand white rabbits, each weighting 2000 to 2500 gm. Twenty animals were used for the control group and 12 for the experimental group. A unilateral external fixation device was applied to the left mandible. The mandibles were lengthened at 1 mm per 24 hours for 10 days. Five rabbits from the control group and three from the experimental group by random selection were sacrificed on the first day, and at the second, fourth and eighth week of the consolidation period. After lengthening bone densities at the site of the left mandibular bony lengthening were measured by quantitative computer tomography (QCT) and dual energy x-ray absorptiometry (DXA). As a result, the DXA value showed no difference compared to the control group after two week's consolidation. The trabeculae were thicker and had begun to be surrounded by lamellar bone both in the control and experimental groups histologically. In conclusion, the results of this study indicate that the osteogenetic effect in the experimental group was nearly the same as in the control group. If stable fixation and minimal periosteal dissection were performed during the procedure, the latent period would not be an important factor in distraction osteogenesis of membranous bone.

생명공학 SSI 수업에서 나타난 영재 중학생들의 의사결정 변화의 유형 분석

임미연,정슬아 이화여자대학교 사범대학 교과교육연구소 2013 교과교육학연구 Vol.17 No.4

본 연구는 인간복제, GMO, 인간 유전정보의 활용의 세 가지 생명공학주제에 관련된 가상상황을 사용한 SSI수업을 통해 중학생들의 의사결정이 어떻게 변화하는지, 그러한 변화의 양상과 내용을 알아보고자 하였다. 이를 위해서울의 한 대학교 소속 영재원과학 프로그램에 참여하고 있는 중학생 20명에게 3회, 총 12시간에 걸친 수업을 제공하였고, 학생들에게 사전-사후에 주어진 6가지가상상황들에 대하여 입장을 선택하고 그러한 의사결정의 근거 혹은 이유를 서술하도록 하였다. 또한 추가적 정보 수집을 위하여 10명의 학생들에 대한 개인 면담을 수행하였다. 본 연구에서는 사전-사 후 의사결정을 분석의 단위로 사용하여, 6가지가상상황에 대해 20명의 학생들이 내린 112개의 사전-사 후 의사결정 중에서 변화를 보인 58개를 대상으로 변화의 양상과 내용의 이해를 위한 분석을 수행하였다. 분석 결과, 학생들이 보여준 의사결정의 변화는 1) 입장 생성, 2) 입장 변화, 3) 입장 강화, 4) 입장 약화, 그리고 5) 입장 철회의 다섯 가지 양상으로 나타났으며, 다음과 같은 결론을 제공하였다. 첫째, 학생들은 SSI수업에서 제시된 생명공학 쟁점들에 대한 의사결정을 위해 다양한 의미 생성 과정에 적극적으로 개입하는 능동적 학습자로서 SSI수업에 참여하는 양상을 보였다. 둘째, SSI수업에서 제시된 생명공학 쟁점들에 대한 의사결정에 있어, 과학적 지식이나 쟁점 관련 정보뿐 아니라 의사결정 과정에 대한 이해 또한 영향을 미치는 것으로 보였다. 끝으로, 학생들이 수업을 통해 오히려 의사결정에 어려움을 겪게 되는 것으로 보이는 입장 철회나 입장 약화의 변화 유형의 내용 분석은 학생들이 수업을 통해 접하는 새로운 지식이나 다양한 차원의 근거를 적극적으로 의사결정에 반영하고 있는 과정임을, 즉 적극적 학습이 일어나고 있음을 보여준다. 그러므로 중학생의 SSI 교육에 있어 의사결정 자체가 목표가 되는 결과 중심의 접근이 아니라, 의사결정 과정을 학습 과정으로서 바라보는 접근이 필요할 것으로 보인다. The purpose of the study is to examine in what ways middle school students change their decisions on three socioscientific issues (SSIs) in biotechnology. Twenty middle school students who attended a gifted science education program from a university gifted education center participated in a 12-session long SSI program. The students were asked to make pre- and postdecisions over 6 biotechnology related scenarios provided during the SSI program and also to explain their decision rationale. Ten of the students were interviewed to provide further explanations on their decision-making processes. This study used a pair of pre- and postdecisions as a unit of analysis. Of 112 decision pairs, this study used 58 cases that showed changes in the pre- and post- decisions. Analysis identified five types of change patterns including: 1) generating a position, 2) switching positions, 3) strengthening one's position, 4) weakening one's position, and 5) withdrawing a position. Further, the study offers the following results. First, the students were active learners, engaging in diverse sense making processes to make decisions on socioscientific issues in biotechnology. Second, not only scientific knowledge and information, but also understanding of decision-making process, seemed to affect the students' decision-making. Last, when we looked into cases of position withdrawal or weakened positions where the students exhibited difficulties in making a decision, we noted that students worked hard to make use of and integrate newly-provided information and multi-dimensional rationales into their decision making. The study thus proposes that, instead of taking an outcome-oriented perspective which puts an emphasis ondecisions, it is important to approach students' decision making on SSI as a learning process focusing on students' sense- and meaning-making processes.