배양된 사람 피부각질세포의 Na+-K+-ATPase의 특성

서동보,윤경식,백행운,백현환,조용호 慶熙大學校 醫科大學 1994 慶熙 醫大 論文集 Vol.19 No.2

안내각췌피 성형술

최시호,서동보 영남대학교 의과대학 1991 Yeungnam University Journal of Medicine Vol.8 No.1

안내각췌피는 안근륜의 검판전부 및 격막전부의 조기 히방 부착이 근본적인 원인이며 과다한 피부는 이들 근육이상에 수반되는 이차적인 현상이라고 생각된다. 이의 교정을 위해서는 과도피부의 절제와 안근륜의 절제를 동시에 시행하여, 수술 후 반흔형성을 피하고, 눈가의 미용적인 개선도 동시에 가져 올 수 있었다. Epicanthoplasty was performed in 98 patients with the epicanthal fold. Epicanthal fold was classified into three categories-minimal degree, moderate degree, severe degree-according to its severity. In accurate anatomic dissection in medial canthal area, the pathologic mechanism of the formation of the epicanthal fold, I think. are not only the redundancy of skin, but also the early downward insertion of the preseptal and pretarsal portion of orbicularis oculi muscle. A new surgical technique is described for the correction of the epicanthal fold. The procedure is simple to perform and uniformly gives good results.

각종 골대체물질들의 골형성능에 관한 비교연구

설정현,최원희,김정철,홍정수,서동보 大韓成形外科學會 1992 Archives of Plastic Surgery Vol.19 No.4

We studied the bone forming capacity of the various bone substitute materials for the confirmation of bone regeneration with each case i.e Hydroxyapatite(SURGIBON), kiel obne, B.O.P. and bone dust. The bone dust was used for control. In 18 New Zealand white rabbits, four partial thickness bone defects were created on the outer table of parietal bone, which were measured 1.5mm in depth x 8mm in diameter. Bone substitute materials were filled in each bone defect. The animals were sacrified at 2, 4, 6, 8 weeks after taking a plain skull film, and then both macroscopic and microscopic examinations were done. The results were as follows : 1. Hydroxyapatite : good bone regeneration with moderately increased eosinophil. 2. KIEL BONE : no bone regeneration and markedly increased eosinophil. 3. B.O.P. : no evidence of bone growth during postoperative 8 weeks. 4. BONE DUST : persistent osteoblast existed during experimental period, more likely as own bone. We summarized that the hydroxyapatite is a biocompatible matrix implantable as a bone graft substitute and more bone regeneration than other bone substitutes during the experimental period.

임의형 피부피판에 미치는 Chlorpromazine과 Nicotine의 영향에 대한 연구

김정철,이경호,홍정수,설정현,서동보 대한성형외과학회 1992 Archives of Plastic Surgery Vol.19 No.3

The concepts of random-pattern skin flaps and the reliability of its survival are important for those who use skin flap technique in plastic and reconstructive surgical fields. The effects and interrelationships of chlorpromazine and nicotine on random-pattern skin flaps were investigated in 60 Sprague-Dawley rats. This study was composed with 5 groups of chlorpromazine and nicotine administration. Chlorpromazine was adminstered after flap elevation during 14days as 0.6㎎ per 100gm of body weight and nicotine was administered 14 days before flap elevation and 14days after operation as low-dose method. The results were as follows. The experimental group studied with chlorpromazine revealed an increased rate of random-pattern skin flap survival compared with the control group which was treated with normal saline. The group studied with nicotine administration showed significant decrease of skin flap survival than that of the control group studied with normal saline. And the results were confirmed on the basis of light microscopic findings. There was no specific advantage in cessation of nicotine after long use compared with that of continuous use of it by statistical analysis. And the effect of nicotine was continued for 2weeks after cessation of it. Administration of chlorpromazine after elevation of skin flap in long-use nicotine group revealed an increased rate of skin flap survival. The results, suggested that administration of chlorpromazine can increase the survival of random-pattern skin flaps. And the use of nicotine can decrease the survival of random-pattern skin flaps which can be reversed by treatment with chlorpromazine. All these results were supported by light microscopic findings.

수부 연부조직 결손 재건에 유용한 주행형 피부판

김동철,김정헌,서동보 大韓成形外科學會 1988 Archives of Plastic Surgery Vol.15 No.4

To resurface the extensive soft tissue defect of the hand, selection of skin flap is done considering the similar skin character and the thickness of skin of the hand, early rehabilitation, more easier fixation with comfortable hand position, one stage operation with good flap survivality. With regard this, 4 patients have undergon axial flap transfer for reconstruction of extensive soft tissue defect of hand. 3 cases of Reverse Forearm Flap were transferred sucessfully. Relatively wide defect were coverde safely in one stage procedure, it does not need fixation of involved extremity and showed early motion of hand, and it's skin texture and thickness are preper. But there are still much leant about its venous drainage particular caution is needed. 1 case of Superficial Inferior Epigastric Flap was used, and it gave larger amount of skin transfer safely, and more comfortable hand position than abdominal flap. It can be elevated with relatively simple procedure.

모상건막하 근막 이식을 이용한 두드러진 비구순 주름의 교정

서동보,설정현,김정철,김정진,이경호 大韓成形外科學會 1992 Archives of Plastic Surgery Vol.19 No.4

The prominence of nasolabial fold is due to the decreased elasticity of the skin of the cheek as aging process and gives the face a senile appearance. So many different methods of the treatment of the pronounced nasolabial fold have been reported-rhytidoplasty, lipectomy, liposuction, wedge excision, roll up skin method, silicone injection, autofat injection, dermal graft, dermofat graft, fat graft, collagen injection, etc. However, most of the operations have something unsatisfactory in results, we used grafts of subgaleal fascia for correction of pronounced nasolabial fold. Subgaleal fascia is located under galea aponeurosis and has been termed as loose areolar tissue consisted of three-layered structure histologically. Using graft of subgaleal fascia that is malleable and little absorbable, through the intraoral incision and the subcutaneous tunnel, we augumented the nasolabial fold. All procedures were ceomfortablly performed under local anesthesia and we have had the period of follow up form 4 months to 11 months and have gotten satisfactory results in 4 cases. The advantages of this method are as follows ; 1) The procedure was simple and time-sparing. 2) The grafted materials were little absorbable. 3) External scars were not seen. 4) The donor site morbidity was minimal.

전흉 및 견갑부의 비후성 및 켈로이드 반흔에 대한 임상적 연구 ( Clinical Study of Hypertrophic Scar and Keloid Scar on Anterior Chest and Shoulder Area )

서동보(Dong Bo Suh),홍성표(Sung Pyo Hong),이두형(Doo Hyung Lee) 경희대학교 경희의료원 1990 慶熙醫學 Vol.6 No.2

5-FU연고의 국소도포법에 의한 각화극세포종 치험례

서동보,오석준 大韓成形外科學會 1988 Archives of Plastic Surgery Vol.15 No.2

Keratoacanthoma is a benign neoplasm that develops as a protruding mass especially on the central part of face. We experienced a case of keratoacanthoma that developed on the nasal columella. Excision of this lesion would have required reconstructive surgery with the likelihood of permanant deformity. We treated it with 5-FU ointment daily for 4 weeks. This treatment suggests that topical application of 5-FU ointment is an effective alternative to conventional methods of treating keratoacanthoma.

HYDROXYAPATITE(SURGIBONE)의 임상적 응용

홍정수,서동보,김정철,설정현,정재호 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.2

Surgibone, which consists of naturals derived from a bovine source. were examed in terms of biocompatibility and osteoconductivity when used for reconstruction of craniofacial deformity. Surgibone, like porous hydroxyapatite, was found to be incorporated into the host tissue without significant inflammation. We knew the Surgibone was as good as porous hydroxyapatite in terms of its biocompatibility and osteoconductivity. We used the Surgibone for reconstruction of congenital or acquired deformity of craniofacial region in 6 patients, e. g. chin(1case), mandible(1case), maxilla(2cases), malar(2cases). The results were excellent without any significant problems during 6 to 12 months after operation with a mean of 9.3 months period. The results summarized as followings ; 1)the Surgibone is a biocompatible matrix implantable as a bone graft substitute and shows more bone regeneration than other bone substitutes.2)the adequate fixation may allow earlier and more efficient ingrowth of perivascular tissue and osteoprogenitor cells(osteoconduction).3)We need longer follow up period for exact confirmation of new bone formation without any significant complications.

경부식도의 재건

서장수,서동보,이경호,김정철,차규호 영남대학교 의과대학 1992 Yeungnam University Journal of Medicine Vol.9 No.1

저자들은 1991년 10월부터 1992년 2월까지 본원 이비인후과를 통해 내원하였던 3명의 환자를 대상으로 경부식도 재건 목적으로 유리 전완피판술 2폐, 전흉부 축형피판술 1례를 시행하였으며 다음과 같은 결과를 얻어 이에 문헌고찰과 함께 보고하는 바이다. 1. 유리 전완피판술을 이용하여 피판의 한쪽변을 deepithelization한 수 이중봉합 하였으며, 원위부는 완만한 S자 모양으로 도안하고 하부식도에 틈을 만들어 피판을 삽입함으로서 문제점으로 제기되어온 하부식도문합부 협착, 누공형성등의 합병증을 해결할 수 있었다. 2. 술전 방사선 치료로 수혜부의 혈관을 이용하지 못할때에는 전흉부 축형피판술을 사용하여 만족할 만한 결과를 얻을 수 있었다. 3. 공장 전이술의 합병증인 개복의 번거러움과 수술후 장폐색증, 운동장애, 연하곤란, 음식물의 역류등의 문제점을 해결할 수 있었다. Microvascular tissue transfers have facilitated primary closure of various complex defects after radical ablation of head and neck cancers. From Oct 1991 to Feb 1992, we used forearm free flap in two patients and delto-pectoral flap in one patient who had preoperative irradiation for pharyngoesophageal reconstruction. The stricture and fistular formation were most troublesome complication in forearm free flap, so we designed as lazy S shape in distal flap margin to prevent circular contraction and longitudinal margin was deepithelized (5㎜) and sutured double layer to withstand fistular formation and this can be considered useful in place of a free jejunal transfer.