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인후두위산역류증(Laryngopharyngeal Reflux: LPR)의 치료에 대한 RabeprazoleSodium(Parietd)의 임상효과와 안전성 검토
정광윤,전병선,고상현,권기환,권순영,권중근,김동영,김상철,김성완,김영모,김영호,김윤환,김장묵,Jung, K.W.,Jun, B.S.,Ko, S.H.,Kwon, K.H.,Kwon, S.Y.,Kwon, J.K.,Kim,, D.Y.,Kim,, S.C.,Kim,, S.W.,Kim,, Y.M.,Kim,, Y.H.,Kim,, Y.H.,Kim,, J.M. 대한기관식도과학회 2004 大韓氣管食道科學會誌 Vol.10 No.2
Background and objective : Rabeprazole is a new generation proton pump inhibitor, which has a rapid onset after first dose, predictable efficacy in all patients regardless of CYP2C19 genotype status, and less nocturnal acid breakthrough. The aim of the study is to investigate clinical efficacy and safety of rabeprazole sodium (Pariet 10mg qd)when administered once daily to patients with laryngopharyngeal reflux(LPR) disease. Methods : Among the patients who had visited the Department of Otolaryngology, those with LPR symptoms, had undergone laryngoscopy. Symptoms and endoscopic laryngeal sings were recorded initially, at 1 month, 2 months, 3 months, and more than 3 months, All patients were evaluated for clinical efficacy on the basis of symptom scores, reflux finding score(RFS), and side effects. Results : In general, most symptom scores and RFS improved over the time. Efficacy of the Pariet on LPR-related symptoms were $63.2\%,\;77.5\%,\;78.7\%,\;and\;90.9\%$ before 4 weeks, 4 to 8 weeks, 8 to 12 weeks, and after 12 weeks respectively. Efficacy on the RFS were $61.8\%,\;78.4\%,\;82.9\%,\;and\;85.5\%$ before 4 weeks, 4 to 8 weeks, 8 to 12 weeks, and after 12 weeks respectively. Pariet was well tolerated and was associated with few drug-related side effects. Conclusion Because of its efficacy and safety, Pariet may prove to be an alternative to currently available proton pump inhibitors.
로봇 팔의 뇌 신호로부터 유도된 3D 좌표 추적을 위한 Guidance Law 적용에 관한 연구
김윤재,박성우,김원식,염홍기,서한길,이용우,방문석,정천기,오병모,김준식,김유단,김성완,Kim, Y.J.,Park, S.W.,Kim, W.S.,Yeom, H.G.,Seo, H.G.,Lee, Y.W.,Bang, M.S.,Chung, C.K.,Oh, B.M.,Kim, J.S.,Kim, Y.,Kim, S. 대한의용생체공학회 2014 의공학회지 Vol.35 No.3
It is being tried to control robot arm using brain signal in the field of brain-machine interface (BMI). This study is focused on applying guidance laws for efficient robot arm control using 3D coordinates obtained from Magnetoencephalography (MEG) signal which represents movement of upper limb. The 3D coordinates obtained from brain signal is inappropriate to be used directly because of the spatial difference between human upper limb and robot arm's end-effector. The spatial difference makes the robot arm to be controlled from a third-person point of view with assist of visual feedback. To resolve this inconvenience, guidance laws which are frequently used for tactical ballistic missile are applied. It could be applied for the users to control robot arm from a first-person point of view which is expected to be more comfortable. The algorithm which enables robot arm to trace MEG signal is provided in this study. The algorithm is simulated and applied to 6-DOF robot arm for verification. The result was satisfactory and demonstrated a possibility in decreasing the training period and increasing the rate of success for certain tasks such as gripping object.