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최성우,이봉섭,곽명화,윤철종,박승조 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.2
Chromium occurs naturally in the earth's crust as well as in air, surface, and ground water. However, chromium is released to the environment in much larger amounts as a result of human activities. Hexavalent chromium, Cr(Ⅵ), is very soluble in water in natural environment and very toxic, carcinogenic, and mutagenic in animal and man. On the other hand trivalent chromium, Cr(Ⅲ), is less toxic and less soluble and thus is a lesser problem. This study has been carried out in order to reduce toxicity of Cr(Ⅵ) by an Escherichia coli strain. After adding E. Coli., the results were obtained from concentration of total Cr, Cr(Ⅵ). Cr(Ⅲ), pH, turbidity, and VSS in aerobic condition was summarized as follows : After 48hr aerobic condition in experiment of synthetic wastewater, the reduction rate of Cr(Ⅵ) was 20%. Also, the reduction rate of Cr(Ⅵ) was 60% in experiment of raw wastewater.
Proteomic Analysis of the Human Erythropoietin Transgenic Pig Testis
Myoung-Seob Choi,In-Sui Hwang,Eun-Jin Kim,Jae-Seok Woo,Seunghoon Lee,Min-Ji Kim,Min-Ji Kim,Sung-June Byun,Won-Kyoung Chang,Nam-Hyung Kim,Jin-Ki Park,Hwi-Cheul Lee 한국동물생명공학회(구 한국동물번식학회) 2008 Reproductive & developmental biology Vol.32 No.2
Proteomic Analysis of the Human Erythropoietin Transgenic Pig Testis
Myoung-Seob Choi,In-Sui Hwang,Eun-Jin Kim,Jae-Seok Woo,Seunghoon Lee,Min-Ji Kim,Min-Ji Kim,Sung-June Byun,Won-Kyoung Chang,Nam-Hyung Kim,Jin-Ki Park,Hwi-Cheul Lee 한국동물번식학회 2008 Reproductive & Developmental Biology(Supplement) Vol.32 No.2s
Choi, Il-Dong,Ryu, Ju-Hee,Lee, Dong-Eun,Lee, Myoung-Hee,Shim, Jae-Joong,Ahn, Young-Tae,Sim, Jae-Hun,Huh, Chul-Sung,Shim, Wang-Seob,Yim, Sung-Vin,Chung, Eun-Kyoung,Lee, Kyung-Tae Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-
<P>To evaluate the pharmacokinetics of compound K after oral administration of HYFRG and RG in humans, an open-label, randomized, single-dose, fasting, and one-period pharmacokinetic study was conducted. After oral administration of a single 3 g dose of HYFRG and RG to 24 healthy Korean males, the mean (±SD) of AUC<SUB>0–<I>t</I></SUB> and <I>C</I><SUB>max</SUB> of compound K from HYFRG were 1466.83 ± 295.89 ng·h/mL and 254.45 ± 51.20 ng/mL, being 115.2- and 80-fold higher than those for RG (12.73 ± 7.83 ng·h/mL and 3.18 ± 1.70 ng/mL), respectively; in case of Sprague Dawley rats the mean (±SD) of AUC<SUB>0–<I>t</I></SUB> and <I>C</I><SUB>max</SUB> of compound K from HYFRG was 58.03 ± 32.53 ng·h/mL and 15.19 ± 10.69 ng/mL, being 6.3- and 6.0-fold higher than those from RG (9.21 ± 7.52 ng·h/mL and 2.55 ± 0.99 ng/mL), respectively. <I>T</I><SUB>max</SUB> of compound K in humans and rats was 2.54 ± 0.92 and 3.33 ± 0.50 h for HYFRG and 9.11 ± 1.45 and 6.75 ± 3.97 hours for RG, respectively. In conclusion, the administration of HYFRG resulted in a higher and faster absorption of compound K in both humans and rats compared to RG.</P>
성장호르몬 결핍 성인에서 성장호르몬 투여가 심혈관 질환의 표지자에 미치는 영향
최형섭 ( Hyung Seob Choi ),김상수 ( Sang Soo Kim ),고근준 ( Kun Joon Ko ),이은재 ( Eun Jae Lee ),박일운 ( Il Woon Park ),박태운 ( Tae Woon Park ),한서구 ( Seo Goo Han ),우명렬 ( Myoung Lyeol Woo ),조지훈 ( Ji Hoon Cho ),홍성일 ( S 대한내과학회 2005 대한내과학회지 Vol.68 No.5
목적 : 성인 성장호르몬 결핍증 환자에서 3개월간의 성장호르몬 투여가 체중, 체질량지수, 허리둘레와 같은 신체검사결과, 혈당, 지질수치, 혈압 등의 잘 알려진 심혈관 질환의 위험인자들과 C-반응단백 및 PAI-1과 같은 염증반응인자들에 미치는 영향을 위약-대조군 연구를 통해 조사하였다. 방법 : 총 37명의 성인형 성장호르몬 결핍증 환자들과 65명의 정상인이 임상시험에 참여하였다. 시험시작 전과 3개월 후에 키, 몸무게, 허리둘레, 엉덩이둘레를 측정하였 Background : Subjects with growth hormone-deficiency (GHD) have increased cardiovascular mortality, and growth hormone (GH) replacement may modulate cardiovascular disease risk. Therefore, we evaluated the effects of GH administration on the markers of ca
한국인 산모와 신생아에서 NANB 간염과 B 형 간염에 관한 연구
최관수(Gwan Su Choi),김지운(Ji Woon Kim),장영호(Yung Ho Chang),오은아(Eun A O),양인애(In Ae Yang),유영근(Young Geun Ryoo),이봉섭(Bong Seob Lee),정남기(Nam Ki Jong),오영종(Young Zong Oh),남명숙(Myoung Soog Nam),임순선(Soon Seon Lim),김 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2
N/A To assess the frequency of hepatitis in pregnant women, we examined the findings of the physical examination, medical history, liver function tests and viral markers in 7,580 pregnant women who delivered at St. Columbans Hospital in Mokpo City from April 1st, 1985 to June 30th, 1988. We compared the characteristics of hepatitis B in 28 mothers and 17 newborn infants, and of non-A, non-B hepatitis in 17 mothers and 61 newborn infants, The results were as follows; 1) Among 7,580 pregnant women, there were 629 cases (8.30%) of HBV carriers. Abnormal elevation of transaminase at delivery was noted in cases of hepatitis A (2, 0.03%), hepatitis B (25, 0. 33%), NANB hepatitis (57, 0.75%) toxemia (9, 0.12%) and drug induced hepatitis (1, 0,01%). 2) The earliest elevation of transaminase was noted at 3 months in 9 hepatitis B infants (6, 66.7%) and 61 NANB hepatitis infants (57, 93.4%). The highest elevation of transaminase was noted at 3 months in 61 NANB hepatitis infants (41, 67. 2%) and seemed to be delayed in 9 hepatitis B infants due to the effect of vaccine. 3) Abnormal transaminase was normal within 6 months in 17 cases (60.7%) of 28 mothers with hepatitis B, and 14 cases (82.4%) of 17 mothers with NANB hepatitis. If we test and observe for )onger time the cases of chronic hepatitis with intermittent elevation of transaminase may increase more. Twenty-seven of 28 hepatitis B mothers were positive for HBsAg for more than 1 year. Duration of abnormal transaminase in hepatitis B infants was much different by the vaccination, but total number of cases was very small. Among 61 NANB hepatitis infants, continuous elevation of transaminase was noted in 5(62.5%) of 8 infants who had no imrnunoprophylaxis, 19(55.9%) of 34 infants who received HBIG & Hepavax, 5(26.3%) of 19 infants who received gamma-globulin. There was slight but not significant inhibition of persistence of abnormal transaminase in group of gamma-globulin injection (0.05<p<0.1). The mean level of maximal ALT was higher in hepatitis B (148.32+162.47 IU) than in NANB hepatitis mothers (76.53<53.14 IU). It was similar in infants of both hepatitis B & NANB, and lower in infants who received Hepavax, gamma-globulin but it was not statistically significant. 4) Among the factors which may influence the elevation of ALT in hepatitis infants the level of ALT in hepatitis mothers had no influence. The immunoprophylaxis with HBIG & hepavax for hepatitis B infants, gamma-globulin for NANB hepatitis seemed to inhibit the elevation of ALT in infants, but not signficantly. ALT was normal in 5 infants (23.8%) of 21 HBeAg positive hepatitis B mothers and in 6 infants (85.7%) of 7 HBeAg negative hepatitis B mothers. There was significant elevation of ALT in infants of HBeAg positive hepatitis B mothers (p<0.0001). The results suggest that the prevalence of NANB hepatitis was higher than hepatitis B in Korean pregnant women at the time of delivery. Duration of abnormal transaminase was similar in mothers with hepatitis B and NANB. The time of the earliest and highest elevation of ALT, the mean level of maximal elevation of ALT were similar in infants with hepatitis B and NANB. Duration of abnormal transaminase and maximal elevation of ALT seemed to be decreased by the immunoprophylaxis with HBIG and Hepavax for hepatitis B infants, gamma-globulin for NANB hepatitis infants, but there was a significant difference in hepatitis B infants whose mothers had HBeAg positivity.