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      • KCI등재

        Development of New Cardiac Deformity Indexes for Pectus Excavatum on Computed Tomography: Feasibility for Pre- and Post-Operative Evaluation

        Miyoung Kim,이기열,박형주,김희영,강은영,오유환,서보경,Bo Kyung Je,Eun Jung Choi 연세대학교의과대학 2009 Yonsei medical journal Vol.50 No.3

        Purpose: The aim of this study was to evaluate new cardiac deformity indexes (CDIs) for diagnosis of pectus excavatum as well as morphological assessment of heart on computed tomography (CT). Materials and Methods: We retrospectively evaluated the CT images of the control group (n=200), and the pectus excavatum before and after correction groups (n=178), and calculated the CDIs; cardiac compression index (CCI), and cardiac asymmetry index (CAI). We also calculated chest wall compression index (CWCI) and asymmetry index (CWAI) on the axial images. We performed logistic regression analysis using each index and age as predictor variables. Results: The CDIs (CCI and CAI) were significant (p < 0.05) in the diagnosis of pectus excavatum, regardless of age (p = 0.4033, p = 0.8113). The CWCI and CWAI were significant (p < 0.05) and significantly affected by age (p < 0.05). If we selected 1.82 as the cutoff of the CCI, the sensitivity and specificity were 99.4% and 98%, respectively. The following cutoffs and the sensitivity and specificity were obtained: 1.15 for the CAI gave 94.4% and 94.5%, 3.05 for the CWCI gave 92.1% and 92%, and 1 for the CWAI gave 62.4% and 65%, respectively. The CCI after repair improved from 2.83 ± 0.84 to 1.84 ± 0.33, while the CWCI improved from 4.49 ± 1.61 to 2.57 ± 0.44. Conclusion: CDIs such as the CCI and CAI may be potentially useful to detect and estimate repair for pectus excavatum.

      • KCI등재후보

        A Study of Fall Risk, Fear of Falling, and Depression in Brain Tumor Patients Following Surgery

        ( Miyoung Kim ) 이화여자대학교 간호과학연구소 2015 Health & Nursing Vol.27 No.2

        Purpose: To describe and analyze correlations between the risk of falling, fear of falling, and depression experienced by patients following brain tumor surgery. Methods: Data were collected from January 31 to September 5, 2013, at the neurosurgery unit of a general hospital located in Seoul, Korea. Study participants consisted of patients aged over 20 years who were interviewed within 1 to 4 days of having undergone brain tumor surgery. Data were collected through self-reported structured questionnaires administered to 150 patients, 139 of whom had complete datasets and were thus included in the final analysis. Associations between study variables were analyzed via Pearson`s correlation analysis. Results: Significant correlations were identified between fall risk and fear of falling (r = .505, p < .001), as well as fear of falling and depression (r = .311, p < .001). However, no relationship was observed between fall risk and depression. Conclusion: The study results revealed that fall risk, fear of falling, and depression were high among patients following brain tumor surgery. Further, significant positive correlations were observed between fall risk and fear of falling, as well as fear of falling and depression.

      • KCI등재후보

        Relationship between the Changes of Arterial Blood Gas by Positioning from Prone to Supine and Patients' Survival in ARDS

        Mi Young Kim,Sang Bum Hong,Chae Man Lim,Younsuck Koh Korean Society of Critical Care Medicine 2007 Acute and Critical Care Vol.22 No.2

        BACKGROUND: Prone positioning has been adopted as a strategy to improve oxygenation in patients with refractory acute respiratory distress syndrome (ARDS). After returning to supine position, most of patients show arterial blood gas changes. However, the clinical implications have not been elucidated. This study was aimed to observe the relationship between the arterial blood gas changes followed by changing position from prone to supine and survival of ARDS. METHODS: We analyzed medical data of 53 ARDS patients, who showed improved arterial oxygenation (defined as the increase in PaO2/FiO2 by > or =20 mmHg within 8~12 hour after prone positioning) in a medical intensive care unit from January, 2000 to July, 2006. The patients were returned to supine position when they showed their PaO2/FiO2 > or =150 mmHg. We compared the arterial blood gas changes between the survivor and the nonsurvivor. RESULTS: The survivor has significant pH improvement after position change (the survivor 0.01+/-0.06 vs. the nonsurvivor -0.03+/-0.08; p=.03). The PaO2/FiO2 and FiO2 changes were not different between the survivor (14.44 +/-69.68 and -2.2+/-4.3, respectively) and the nonsurvivor (-7.17+/-83.94 and 1.8+/-6.0, respectively; p=.314 and .843). The patients whose PaO2/FiO2 were deteriorated had higher mortality without statistical significance (p=.305). The PaCO2 changes were not different between two groups (-0.05+/-11.46 vs. 3.47+/-17.62, p=.390). CONCLUSIONS: The early changes in pH differed significantly between the survivor and the nonsurvivor after returning patients to supine position from prone. Whether this marker can be a predictor of survival should be studied further.

      • SCIESCOPUSKCI등재

        Comparison of the chemical compositions and nutritive values of various pumpkin (Cucurbitaceae) species and parts

        Mi Young Kim,Eun Jin Kim,Young-Nam Kim,Changsun Choi,Bog-Hieu Lee 한국영양학회 2012 Nutrition Research and Practice Vol.6 No.1

        Pumpkins have considerable variation in nutrient contents depending on the cultivation environment, species, or part. In this study, the general chemical compositions and some bioactive components, such as tocopherols, carotenoids, and β-sitosterol, were analyzed in three major species of pumpkin (Cucurbitaceae pepo, C. moschata, and C. maxima) grown in Korea and also in three parts (peel, flesh, and seed) of each pumpkin species. C. maxima had significantly more carbohydrate, protein, fat, and fiber than C. pepo or C. moschata (P < 0.05). The moisture content as well as the amino acid and arginine contents in all parts of the pumpkin was highest in C. pepo. The major fatty acids in the seeds were palmitic, stearic, oleic, and linoleic acids. C. pepo and C. moschata seeds had significantly more γ-tocopherol than C. maxima, whose seeds had the highest β-carotene content. C. pepo seeds had significantly more β-sitosterol than the others. Nutrient compositions differed considerably among the pumpkin species and parts. These results will be useful in updating the nutrient compositions of pumpkin in the Korean food composition database. Additional analyses of various pumpkins grown in different years and in different areas of Korea are needed.

      • KCI등재

        Protective effect of dietary chitosan on cadmium accumulation in rats

        Mi Young Kim,Woo-Jeong Shon,Mi-Na Park,Yeon-Sook Lee,Dong-Mi Shin 한국영양학회 2016 Nutrition Research and Practice Vol.10 No.1

        BACKGROUND/OBJECTIVES: Cadmium is a toxic metal that is an occupational and environmental concern especially because of its human carcinogenicity; it induces serious adverse effects in various organs and tissues. Even low levels of exposure to cadmium could be harmful owing to its extremely long half-life in the body. Cadmium intoxication may be prevented by the consumption of dietary components that potentially reduce its accumulation in the body. Dietary chitosan is a polysaccharide derived from animal sources; it has been known for its ability to bind to divalent cations including cadmium, in addition to other beneficial effects including hypocholesterolemic and anticancer effects. Therefore, we aimed to investigate the role of dietary chitosan in reducing cadmium accumulation using an in vivo system. MATERIALS/METHODS: Cadmium was administered orally at 2 mg (three times per week) to three groups of Sprague-Dawley rats: control, low-dose, and high-dose (0, 3, and 5%, respectively) chitosan diet groups for eight weeks. Cadmium accumulation, as well as tissue functional and histological changes, was determined. RESULTS: Compared to the control group, rats fed the chitosan diet showed significantly lower levels of cadmium in blood and tissues including the kidneys, liver, and femur. Biochemical analysis of liver function including the determination of aspartate aminotransferase and total bilirubin levels showed that dietary chitosan reduced hepatic tissue damage caused by cadmium intoxication and prevented the associated bone disorder. CONCLUSIONS: These results suggest that dietary chitosan has the potential to reduce cadmium accumulation in the body as well as protect liver function and bone health against cadmium intoxication.

      • SCIESCOPUSKCI등재

        Dietary modulation of gut microbiota for the relief of irritable bowel syndrome

        Mi-Young Kim,Sang-Woon Choi 한국영양학회 2021 Nutrition Research and Practice Vol.15 No.4

        Irritable bowel syndrome (IBS) is a frequently diagnosed gastrointestinal (GI) disorder characterized by recurrent abdominal pain, bloating, and changes in the stool form or frequency without any structural changes and overt inflammation. It is not a life-threatening condition but causes a considerable level of discomfort and distress. Among the many pathophysiologic factors, such as altered GI motility, visceral hypersensitivity, and low-grade mucosal inflammation, as well as other immunologic, psychologic, and genetic factors, gut microbiota imbalance (dysbiosis), which is frequently found in IBS, has been highlighted as an etiology of IBS. Dysbiosis may affect gut mucosal homeostasis, immune function, metabolic regulation, and even visceral motor function. As diet is shown to play a fundamental role in the gut microbiota profile, this review discusses the influence of diet on IBS occurring through the modulation of gut microbiota. Based on previous studies, it appears that dietary modulation of the gut microbiota may be effective for the alleviation of IBS symptoms and, also an effective IBS management strategy based on the underlying mechanism; especially because, IBS currently has no specific treatment owing to its uncertain etiology.

      • SCIESCOPUSKCI등재

        Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats

        Mi Young Kim,Eun Jin Kim,Young-Nam Kim,Changsun Choi,Bog-Hieu Lee 한국영양학회 2011 Nutrition Research and Practice Vol.5 No.5

        α-Lipoic acid and L-carnosine are powerful antioxidants and are often used as a health supplement and as an ergogenic aid. The objective of this study was to investigate the effects of α-lipoic acid and/or L-carnosine supplementation on antioxidant activity in serum, skin, and liver of rats and blood lipid profiles for 6 weeks. Four treatment groups received diets containing regular rat chow diet (control, CON), 0.5% α-lipoic acid (ALA), 0.25% α-lipoic acid +0.25% L-carnosine (ALA+LC), or 0.5% L-carnosine (LC). Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and lipid peroxidation products, malondialdehyde (MDA) concentrations, were analyzed in serum, skin, and liver. Blood lipid profiles were measured, including triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C). Skin and liver SOD activities of the ALA and LC groups were higher than those of the CON group (P<0.05), but serum SOD activity was higher only in the LC group compared to that in the CON group (P<0.05). Additionally, only liver GSH-Px activity in the LC group was higher than that of the CON and the other groups. Serum and skin MDA levels in the ALA and LC groups were lower than those in the CON group (P<0.05). Serum TG and TC in the ALA and ALA+LC groups were lower than those in the CON and LC groups (P<0.05). The HDL-C level in the LC group was higher than that in any other group (P<0.05). LDL-C level was lower in the ALA+LC and LC groups than that in the CON group (P<0.05). Thus, α-lipoic acid and L-carnosine supplementation increased antioxidant activity, decreased lipid peroxidation in the serum, liver, and skin of rats and positively modified blood lipid profiles.

      • KCI등재

        Removal of Hg(II) ions from aqueous solution by poly(allylamine-co-methacrylamide-co-dimethylthiourea)

        Mi Young Kim,Haein Seo,Tai Gyu Lee 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.84 No.-

        In this study, poly(allylamine-co-methacrylamide-co-dimethylthiourea), a chelating polymer containingamino groups and thiourea, was synthesized and tested for its capacity to remove mercury ions (Hg2+)from aqueous solutions. The structure of the prepared polymer was analyzed and characterized by FTIRand FE-SEM. The effects of various parameters such as pH, contact time, and initial Hg concentration onHg(II) removal were studied. The Hg(II) adsorption reached maximum capacity at equilibrium within 1 h. The Hg ions were adsorbed for 4 h at pH 7. The highest Hg(II) adsorption was obtained at pH 7 and400 mg L 1. The experimental data werefitted to the pseudo-second-order model using kinetic modeling,indicating that the mechanism was chemisorption. In addition, the experimental data werefitted to theLangmuir isotherm model, thus demonstrating that the Hg(II) adsorption process occurred through theformation of a monolayer.

      • KCI등재

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