한국인 혈관성 치매환자에서 아포지단백 E ε4 대립유전자형의 발현빈도

강현욱,박미영 대한치매학회 2002 Dementia and Neurocognitive Disorders Vol.1 No.1

Background: The clinical significance of the apolipoprotein E (Apo E) ε4 allele in vascular dementia (VaD) has been a subject of debate. VaD is the most common subtype of dementia in Korean population. Apo E allele frequencies were evaluated in Korean patients with VaD diagnosed by the Erkinjuntti criteria of subcortical vascular dementia and mini-mental-state examination(MMSE) in this study Methods: Forty patients participated in the study. 20 patients with VaD and 20 controls with no risk factors for stroke who had absolutely normal brain MRI findings The Apo E genotype was determined by the polymerase chain reaction (PCR) and allele specific hybridization using the Apo E typing test kit Results: The Apo E ε4 allele frequency in the VaD group was 20% and was not significantly different from those of normal controls (15%) The severity of dementia assessed by K-MMSE was not different between the VaD patients with Apo E ε4 allele and the VaD patients without Apo E ε4 allele Conclusions: These results did not show neither increased frequency of Apo E ε4 allele in Korean VaD patients, nor any differences in trends compared to control subjects.

의류점포의 서비스품질이 지각된 전환장벽과 점포충성도에 미치는 영향

강미연,홍금희 한국의류학회 2003 한국의류학회지 Vol.27 No.8

This study attempts to understand perceived switching barriers of customers and fashion stores service quality as a core of store loyalty. Medium variations of switching barriers are interpersonal relationships, attractiveness of alternatives and switching costs. Date were collected from 485 subjects who finished their shopping with as self-administered questionnaire. The results were as follows: 1. Classified service quality of clothing stores into 4 ways: VMD of stores of atmosphere, store policy which are involved in store service, sales persons respond and sales persons conviction which are involved in sales service. 2. Service quality of fashion store is related with switching barrier medium variations. 3. Service quality have an influence on stitching barrier medium variations. Its mutual influences increase switching barriers and it gets to be related to the store loyalty. 4. Compared influences of variations to store loyalty between the H department store and the L department store which are research objects. The main difference is that the H department store evaluate personal relationships among service quality, customers and sales persons high compared with the L department store. As the results showed, service quality consists of store service of nonpersonal service area and sales service of personal service. Service quality is related with interpersonal relationships, attractiveness of alternatives and switching costs. It also affects switching barriers and store loyalty.

유방선암의 유형에 따른 c-erbB-2, p53, bcl-2, 그리고 c-myc의 발현

강영근,조현득,오미혜,김의한,양승하 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

Breast carcinoma is a common malignant tumor in female of the korea. Various oncogenes have been found in malignant tumor cells. There were many reports or correlation between the prognosis of patients and c-erbB-2, p53, bcl-2, and c-myc, but is controversial. We performed immunohistochemical stain for above antigenic protein for 80 cases of breast carcinoma and evaluated expression rate of each antigens, and we compared their correlation with prognosis of patients. The results were as follow; 1) The expression rates in breast carcinoma was c-erbB-2 80%, p53 56.3%, bcl-2 51.3% and c-myc 53.8%. 2) c-erbB-2 showed no significant difference according to histologic types, grade, and lymph node metastatic status of breast carcinoma. 3) p53 showed higher expression rate in metastatic cases compared to non-metastatic cases, and it showed higher expression rate according to increasing of grade without significant difference. There is no significant difference according to types. 4) The expression rate of bcl-2 in breast carcinoma be lowed according to increasing of grade. There was no significant difference according to types, side, and status of lymph node metastasis. 5) c-myc showed higher expression rate in non-metastatic cases compared to and metastatic cases, and it showed decreasing expression rate according to increasing of grade without significant difference. There is no significant difference according to types. 6) p53 and bcl-2 in breast carxinoma showed reverse corre1ation(P < 0.05), and bc1-2 and c-myc showed close correlation without statiscally significance. Above results showed that p53 may be related to poor prognosis of the patients and c-myc may be related good prognosis in breast carcinoma. There was reverse correlation between p53 and bcl-2 and bcl-2 and c-myc may be correlated closely. c-erbB-2 and bcl-2 showed no interrelation to prognosis.

유치원 흥미영역에서 유아의 놀이행동 특성 연구

강미희 광주보건대학 2003 論文集 Vol.28 No.-

The purpose of this study is to analyze and understand the characteristics of children's play behavior in six interest centers found in a kindergarten classroom: language area, block area, science area, house area, art area, and area. To do this, the work time of kindergarten program was selected for observation and 5-year-old 12 classes working in interest center were examined an hour over 12 times. A observation tool was based on Parten's six play types classification: unoccupied behavior, onlooker behavior, solitary play, parallel play, associative play, and cooperative play. As a result, the characteristics of children's play behavior found in the kindergarten interest center are as follows: 1. In the interest center, children participated most in block area and language area. And children participated least in science area. Children equally participated in house area, manipulative area, and art area. 2. In the interest center, the play type found most was solitary play and associative play, followed by parallel play and cooperative play. The play type found least was unoccupied behavior and onlooker behavior. 3. The play types found most by interest center included block area-solitary play, manipulative area-solitary play, science area-solitary play, house area-cooperative play, and art area-parallel play. Solitary play was found most in four out of six interests, except house area and art area. The results suggest that the level of environmental structure of interest center has an influence on children's participation level in interest center and that children's play behavior is related ta the characteristics of interest center. Furthermore, it may be inappropriate to explain the characteristics of children's play behavior in interest center in terms of age alone. More complex elements seem to be related.

유치원 교육과정에서 의미하는 통합과 실제 통합교육의 문제

강미희 광주보건대학 2004 論文集 Vol.29 No.-

The essence of integration in child education has various and complex characteristics and many kindergarten teachers understand it in a wrong way or mistakenly accept and interpret it among them. Moreover, even if they have an accurate understanding, their performing ability is quite low in the practice of early childhood education thereby causing disagreement between the theory and practice. Therefore, this study aims to summarize and straighten up the essence of integrated education concretely from various respects, find out various problems of integrated education caused by the practice of early childhood education, and suggest measures to solve these problems.

효과적인 유아교사 교육을 저해하는 요인 분석

강미희 광주보건대학 2002 論文集 Vol.27 No.-

This study aims at examining problems in education of teachers of early childhood education and seeking a method to solve them. Conventional education of teachers of early childhood education is insufficient in training able teachers with professional quality because its curriculum was established on the basis of theoretical knowledge or experience. In addition, although teachers of early childhood education completed the required credits at early childhood education agency and got qualification, they couldn't achieve a satisfactory result in playing the roles of teachers with expertism. Therefore, this study discusses a chair operation with the diversified and whole approaches in early childhood education colleges, optimal utilization of teacher or human resource in community to enhance the availability of and expertism related to early childhood education, close relationship between college and early children education agencies and mutual interchange, extension of joint research and training through cooperations among educator of early childhood education teachers, in service teachers and preservice teachers and conversion of thinking recognizing relation between early childhood education agencies and colleges into real partnership rather than the relation between demander and consumer.

신문광고의 실제요금과 열독률의 상관성

강미선 한국방송광고공사 2006 광고연구 Vol.0 No.71

현재 신문광고는 어느 신문사를 막론하고 대외적으로 발표하는 공식요금과 실제 거래에서 활용되는 실제요금으로 이원화되어 있다. 공식요금은 신문의 명성이나 영향력, 광고효과와 무관하게 이뤄져 있기 때문에 시장에서는 유명무실한 존재인 반면 실제요금은 시장에서 거래되는 단가라는 점에서 실효 광고단가라 할 수 있다. 그러나 실제요금은 신문사에서 철저하게 대외비로 취급하고 있어 자료접근이 어려운 상태이기 때문에 학문적인 관심을 벗어나 있었다. 이번 연구는 신문광고의 대표적인 업종에 속한 기업들의 실제요금 자료를 수집하여 사례분석을 실시했다. 이를 통해 신문광고 요금체계를 좀 더 실체적으로 파악하는데 일차적인 연구목적을 두었다. 이차적으로는 신문의 열독률과 실제요금의 상관성을 분석하여 실제요금이 매체가치를 어느 정도 반영하고 있는가를 파악함으로써 실제요금의 적정성을 평가하는데 목적을 두었다. 이상의 분석결과를 토대로 최종적으로 업종별 요금가이드라인을 제시했다. There are two types of newspaper ad rates. One is formal ad rate, and the other is real ad rate. The former is meaningless in the view that it doesn’t work in market. Instead, the latter is meaningful in the respect that real ad rate is taking effect in market. So I’d like to focus on the real ad rates, even though it’s hard to access the data which is treated as secret informations. Inevitably, I privately gathered the related data from advertisers and/or advertising agencies. And then I conducted case study with samples of leading categories of business. Through this process, I’d like to grasp unknown newspaper ad rate system, if possible. In addition, the second aim of this research is to analyse the relationship of ad rate with readership data. The newspaper readership is very important in the point of its function as the index of media value. The more newspaper ad rates reflect the readership, ad price can be evaluated proper. Finally, I made the guide line table of newspaper ad rate by categories of business.

서데그 헤더야트(??)의 生涯와 文學

康眉瓊 韓國外國語大學校附設中東問題硏究所 1983 硏究論叢 Vol.1983 No.4

중등 교사 양성을 위한 미적분학 강좌 운영방안

강미광 한국수학교육학회 2003 수학교육 Vol.42 No.4

The main purpose of this work is to propose programs of calculuc for the department of mathematics education of teacher training universities. There is a description of the characteristics, goal and contents of calculus course for pre-service teacher, followed by principles for teaching the subject. We suggest the constituents and something being kept in mind for each part in calculus.

지방자치단체 집행기관의 관리능력에 관한 연구 : 주민인식을 중심으로

강성철,김상구,홍미영 부산대학교 사회과학대학 1999 社會科學論叢 Vol.18 No.1

This study is aimed to analyze and evaluate the managerial capacity of executive organization in local government in terms of the resident's perception. The capacities of local government to activate local autonomy are as follows : political, financial, managerial capacity. Among these capacities, this study is defined to managerial capacity. The reason why analyzes the managerial capacity fo executive organization in local government is that it plays major role in activating local autonomy. The managerial capacity is defined as managerial efforts and means to attain goals of local autonomy in executive organization in local government. In this study, variable for analyzing the managerial capacity of executive organization of local government are as follows : the leadership of chief's in a local government, the capacity of local employees, the grasping and acceptance abilities of citizen's demand, managerial capacity of conflicts, policy making capacity, implementing capacity and inducing capacity of citizen participation. This study analyzed 294 persons (male : 152, female : 134, missing value : 8) as samples. The methods of analysis were used as frequency analysis. The results of this analysis are as follows : most residents estimate these capabilities of local executive organization very low. Especially inducing capacity of citizen participation and the leadership of chief's in local government are shown as lowest among other capacities. But residents evaluate managerial capacity of conflicts and policy making capacity higher than other capacities. This results of these analysis could be interpreted on the ground that elected chief of local government specially emphasizes to solve conflicting problems in local government. And the importances of variables composing managerial capacitites is that managerial capacities of conflicts is highest, and then policy making, acceptance capacity, employee capacities, but the importance of the inducing capacity of citizen participation is lowest. Taken together, although the local autonomy of Korea may established the institutional framework, it may not be easy to say that a local government works properly in local society. And so, to extend the managerial capacity of executive organization to activate local autonomy have to change authorities-oriented administration to client-orient one. And above all concerns of central government, local assembly, region communities are needed to enhance managerial capacity of executive organization.