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Some case studies of hydrodynamic bearings in power plants in Japan
Tanaka Masato 한국트라이볼로지학회 2003 한국트라이볼로지학회 학술대회 Vol.37 No.-
The service reliability of power plants strongly depends on the excellent performance and integrity of hydrodynamic bearings. Consequently, the bearings must be properly designed so as to control vibration amplitudes of rotor due to mass unbalance in passing critical speeds and also suppress self-excited vibrations of rotor even over maximum rated speeds. Furthermore, the bearings must be designed so as to maintain required tribological performance even under severe operating conditions. However, various tribological troubles have been experienced in power plants in Japan. The actual troubles are analysed, focusing on not only direct mechanical causes but also specific bearing designs that surfaced the troubles. Furthermore human factors that decided such designs are also studied. The powerful database of troubles and analyses will contribute greatly to designing advanced power plants with enhanced service reliability in the future. To this end, trouble information should be disclosed, shared and transferred limitlessly. Cooperation of users of power plants is essential to making more advanced design specifications, because no one has easier access to operating and trouble information of power plants than users.
( Masato Funazumi ),( Takeshi Namiki ),( Yumi Arima ),( Kohei Kato ),( Kohei Nojima ),( Kentaro Tanaka ),( Keiko Miura ),( Hiroo Yokozeki ) 대한피부과학회 2016 Annals of Dermatology Vol.28 No.4
Primary penile melanomas are rare tumors that represent less than 0.1% of all melanomas. We report a case of a 60-year-old Japanese male with a mucosal penile melanoma and describe an increased CD8+ T cell infiltration in brain after dacarbazine (DTIC) administration. After partial penectomy and left inguinal lymphadenectomy, he developed multiple lung, bone, spleen, brain and skin metastases. He was treated with interferon-β, DTIC and nivolumab. However, the metastases were not reduced in size. Immunohistochemistry showed an increase of CD8+ T cell infiltration and programmed death-ligand 1 (PD-L1) expression after the administration of DTIC, but the expression of programmed cell death protein 1 (PD-1) was negative. We speculate that DTIC exerted immunostimulatory effects, but nivolumab was ineffective due to the negative expression of PD-1 and/or an insufficient infiltration of CD8+ T cells. Although this is only one case, this case report could be the first step to discuss the development of effective therapies against melanoma to take advantage of the increased CD8+ T cell in-filtration elicited by chemotherapeutic agents. It would be beneficial to pay more attention to the relationship between DTIC and immune checkpoint modulators. (Ann Dermatol 28(4) 486∼490, 2016)
Kazushi Tanaka,Katsumi Shigemura,Mototsugu Muramaki,Satoru Takahashi,Hideaki Miyake,Masato Fujisawa 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.7
Purpose: To evaluate the efficacy of using 3-tesla (T) magnetic resonance imaging (MRI) diagnosis of extracapsular extension (ECE) for decision-making about neurovascular bundle (NVB) preservation in robot-assisted radical prostatectomy (RARP) for prostate cancer (PC). Materials and Methods: We prospectively collected data on PC patients (n=67) who underwent preoperative 3-T MRI before RARP. The choice between nerve sparing or resection was based on 3-T MRI findings of ECE. We compared the MRI findings with the pathological data on surgical margins. Our clinical staging in this study was defined only by MRI. Results: When the data were divided by prostate lobe (right lobe or left lobe, n=134),3-T MRI showed 28 positive cases of ECE in 134 prostate lobes, allowing NVB preservation in 42 cases (31.3%). Nerve-sparing surgery was achieved in 38.7% of cases in which clinical T2 staging by MRI was reported. The pathological data revealed that 10 of 134 prostate lobes had positive ECE. The overall sensitivity, specificity, positive predictive value, and negative predictive value for predicting stage T3 (positive ECE) by side were 60.0% (12 of 20 sides), 86.0% (98 of 114 sides), 42.9% (12 of 28 sides), and 92.5% (98 of 106 sides), respectively. Conclusions: Three-T MRI prior to RARP enables the use of ECE diagnosis to guide decision-making about NVB preservation, with comparatively high specificity and negative predictive value. Further prospective studies are underway to reach more definitive conclusions.
Discrimination between Malignant and Benign Vertebral Fractures Using Magnetic Resonance Imaging
Tomoyuki Takigawa,Masato Tanaka,Yoshihisa Sugimoto,Tomoko Tetsunaga,Keiichiro Nishida,Toshifumi Ozaki 대한척추외과학회 2017 Asian Spine Journal Vol.11 No.3
Study Design: Retrospective analysis using magnetic resonance imaging (MRI). Purpose: To identify MRI features that could discriminate benign from malignant vertebral fractures. Overview of Literature: Discrimination between benign and malignant vertebral fractures remains challenging, particularly in patients with osteoporosis and cancer. Presently, the most sensitive means of detecting and assessing fracture etiology is MRI. However, published reports have focused on only one or a few discriminators. Methods: Totally, 106 patients were assessed by MRI within six weeks of sustaining 114 thoracic and/or lumbar vertebral fractures (benign, n=65; malignant, n=49). The fractures were pathologically confirmed if malignant or clinically diagnosed if benign and were followed up for a minimum of six months. Seventeen features were analyzed in all fractures’ magnetic resonance images. Single parameters were analyzed using the chi-square test; a logit model was established using multivariate logistic regression analysis. Results: The chi-square test revealed 11 malignant and 4 benign parameters. Multivariate logistic regression analysis selected (i) posterior wall diffuse protrusion (odds ratio [OR], 48; 95% confidence interval [CI], 4.2–548; p =0.002), (ii) pedicle involvement (OR, 21; 95% CI, 2.0–229; p =0.01), (iii) posterior involvement (OR, 21; 95% CI, 1.5–21; p =0.02), and (iv) band pattern (OR, 0.047; 95% CI, 0.0005–4.7; p =0.19). The logit model was expressed as P=1/[1+exp (x)], x=−3.88×(i)−3.05×(ii)−3.02×(iii)+3.05×(iv)+5.00, where P is the probability of malignancy. The total predictive value was 97.3%. The only exception was multiple myeloma with features of a benign fracture. Conclusions: Although each MRI feature had a different meaning with a variable differentiation power, combining them led to an accurate diagnosis. This study identified the most relevant MRI features that would be helpful in discriminating benign from malignant vertebral fractures.
Thermoelectric Power in Single-crystalline CeRhSi3
Hidekazu A. Tanaka,Naofumi Aso,Masato Hedo,Takao Nakama,Yoshinao Takaesu,Hiroki Iida,Noriaki Kimura,Haruyoshi Aoki 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12
The thermoelectric power S of a heavy-fermion superconductor CeRhSi3 has been measured attemperatures from 2.0 K to 300 K under hydrostatic pressures up to 2.7 GPa in order to clarify theKondo effect in CeRhSi3. S exhibits a large value of up to 60 µV/K, which is characteristic of heavyfermionsystems. S shows a maximum in its temperature dependence mainly due to the Kondoeffect, and its maximum temperature TSmax gradually increases from 96 K at ambient pressure to127 K at 2.7 GPa when a pressure is applied.