한국 연안에서 Mussel(Mytilus edulis)의 중금속의 생물 농축

이인숙,송준임,박경숙,최병래,노분조 이화여자대학교 생명과학연구소 1995 생명과학연구논문집 Vol.6 No.-

본 연구는 남한 연안의 오염도를 파악하기 위해 마산만, 온산만, 대산공업 단지 및 비오염구에서 해수, 퇴적물 및 진주담치의 구리, 납, 아연 및 카드뮴의 농도를 조사하였다. 해수의 용존성 구리, 납, 아연 및 카드뮴의 농두는 각각 0.29~0.79 ㎍/l, 0.03~0.08 ㎍/l, 0.19~2.01 ㎍/l, 0.01~0.05 ㎍/l 범위를 나타냈으며, 납(p<0.001)과 아연 농도(p<0.01)는 오염구와 비오염구 간에 유의적인 차이가 있었다, 퇴적물의 구리, 납, 아연 및 카드뮴의 농도는 13~55 ㎍/g, 26~101 ㎍/g, 51~263 ㎍/g, 0.8~2.2 ㎍/g 범위를 모였으며, 오염구와 비오염구 사이에 카드뮴 농도는 유의적인 차이를 나타냈다(p<0.05). 진주담치의 구리, 납, 아연 및 카드뮴 농도는 0.69~2.27 ㎍/g, 0.29~1.50 ㎍/g, 13.57~52.90 ㎍/g, 0.09~0.85 ㎍/g 범위로 나타났고, 각 중금속 농도가 오염구와 비오염구 사이에 유의적인 차이를 보이지 않았다. 본 연구에서 오염구에 있는 진주담치의 중금속 농도는 자연 상태인 비오염구에서의 농도와 유사한 값으로 이는 연안 해수가 중금속에 의해 크게 오염되지 않은 것으로 사료된다. This study was carried out to investigate the concentration of Cu, Pb, Zn and Cd in seawater, sediments and Mytilus edulis at Massan Bay, Onsan Bay, Daesan industrial complex and unpolluted area for the degree of contamination on the coast of Korea. The concentrations of dissolved Cu, Pb, Zn and Cd in seawater showed the ranges of 0.29~0.79 ㎍/l, 0.03~0.08 ㎍/l, 0.19~2.01 ㎍/l, 0.01~0.05 ㎍/l, respectively. The concentrations of Pb(p<0.001) and Zn(p<0.01) showed the significant difference between the concentrations of unpolluted area. There were the ranges of 13~55 ㎍/g, 26~101 ㎍/g, 51~263 ㎍/g and 0.8~2.2 ㎍/g in the concentration of Cu, Pb, Zn and Cd of sediments. The concentrations of Cu were significantly different between the contaminated and unpolluted area. The concentration of Cu, Pb, Zn and Cd, in the Mythilus edulis showed the ranges of 0.69~2.27 ㎍/g, 0.29~1.50 ㎍/g, 13.57~52.90 ㎍/g and 0.09~0.85 ㎍/g respectively. These concentrations of trace metal in Mytilus edulis were not significantly different with sites. Trace metal contents of Mytilus edulis in the contaminated site were similar th those in the unpolluted area. This is thought that metal concentration in coastal seawater were not relatively serious.

L-Deprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration

Ryu, I.,Ryu, M. J.,Han, J.,Kim, S. J.,Lee, M. J.,Ju, X.,Yoo, B. H.,Lee, Y. L.,Jang, Y.,Song, I.-C. Spandidos Publications 2018 Oncology reports Vol.40 No.6

DHS-21, a dicarbonyl/l-xylulose reductase (DCXR) ortholog, regulates longevity and reproduction in Caenorhabditis elegans

Son, L.T.,Ko, K.M.,Cho, J.H.,Singaravelu, G.,Chatterjee, I.,Choi, T.W.,Song, H.O.,Yu, J.R.,Park, B.J.,Lee, S.K.,Ahnn, J. North-Holland Pub ; Elsevier Science Ltd 2011 FEBS letters Vol.585 No.9

Dicarbonyl/l-xylulose reductase (DCXR) converts l-xylulose into xylitol, and reduces various α-dicarbonyl compounds, thus performing a dual role in carbohydrate metabolism and detoxification. In this study, we identified DHS-21 as the only DCXR ortholog in Caenorhabditis elegans. The dhs-21 gene is expressed in various tissues including the intestine, gonadal sheath cells, uterine seam (utse) cells, the spermathecal-uterus (sp-ut) valve and on the plasma membrane of spermatids. Recombinant DHS-21 was shown to convert l-xylulose to xylitol using NADPH as a cofactor. Dhs-21 null mutants of C. elegans show defects in longevity, reproduction and egg-laying. Knock-down of daf-16 and elt-2 transcription factors affected dhs-21 expression. These results suggest that DHS-21 is a bona fide DCXR of C. elegans, essential for normal life span and reproduction.

Lower bounds for blow-up time in a nonlinear parabolic problem

Payne, L.E.,Song, J.C. Academic Press 2009 Journal of mathematical analysis and applications Vol.354 No.1

For a parabolic problem with a gradient nonlinearity which was introduced by Chipot and Weissler [M. Chipot, F.B. Weissler, Some blow up results for a nonlinear parabolic problem with a gradient term, SIAM J. Math. Anal. 20 (1989) 886-907] (see also [B. Kawohl, L.A. Peletier, Observations on blow up and dead cores for nonlinear parabolic equations, Math. Z. 202 (1989) 207-217]), the question of blow-up is investigated. Specifically, if the solution blows up, a lower bound for the time of blow-up is derived

노인의 병원 선택 경험

김단비,김민지,김해솔,김희정,박윤선,손유경,송예진,유예림,이다예,이서영,이지현,강숙정,김부연 이화여자대학교간호학회 2020 이화간호학회지 Vol.- No.54

Purpose: The purpose of this descriptive study was to examine hospital choice factors among elderly patients to understand their experience and use as data to move towards senior-friendly hospitals. Methods: The individual in-depth interviews were conducted from August 13th to 18th, 2019. The participants consisted of eight senior citizens aged 65 and above that suffered from chronic illnesses and had regular hospital visits. Results: This study found that when elderly patients choose the hospital, they considered ‘awareness such as brand name of the hospital', ‘quality of medical service',‘convenience', ‘healthcare team / hospital employee', ‘personal experience', ‘children’s recommendation’ and etc,. The significant point was that all these factors were related to personal experiences from specific hospitals. Conclusion: This study analyzed the hospital choice factors of the elderly patients with high hospital utilization rates and found that the results were mainly affected by the distinct characteristics of elderly patients. The implications of this study are that we proposed further research directions and means for the improvement of the hospital. We suggest hospitals to increase labor allocation for elderly patients with difficulties dealing with unmanned systems such as kiosk and strengthen the role of healthcare providers as instructors for higher satisfaction.

Genetic Diversity Analysis of Water Buffalo (Bubalus bubalis L.) Populations in the Philippines Using Bovine Microsatellite Markers

Cacho, R. G. C.,Han, J. M.,Herrera, J. R. V.,Oh, J.-D.,Seong, J.,Song, K.-D.,Cruz, L. C.,Kong, H. S.,Lee, H. K. COLLEGE OF VETERINARY MEDICINE, UNIVERSITY OF THE 2013 Philippine journal of veterinary medicine Vol.50 No.1

XAS and XMCD studies of amorphous FeCo-based ribbons

Gautam, S.,Kane, S.N.,Park, B.-G.,Kim, J.-Y.,Varga, L.K.,Song, J.-H.,Chae, K.H. North-Holland 2011 Journal of non-crystalline solids Vol.357 No.11

This paper reports x-ray absorption spectroscopy (XAS) and x-ray magnetic circular dichroism (XMCD) studies at Fe L<SUB>3,2</SUB> and Co L<SUB>3,2</SUB>-edges to investigate the electronic structure of (Fe<SUB>100-x</SUB>Co<SUB>x</SUB>)<SUB>78</SUB>Si<SUB>9</SUB>Nb<SUB>3</SUB>B<SUB>9</SUB>Cu<SUB>1</SUB> (0<x<95) alloys. The influence of controlled Co addition on electronic structural and magnetic properties of (Fe<SUB>100-x</SUB>Co<SUB>x</SUB>)<SUB>78</SUB>Si<SUB>9</SUB>Nb<SUB>3</SUB>B<SUB>9</SUB>Cu<SUB>1</SUB> (x=0, 20, 40, and 60) alloys has been investigated and it has been observed that Co exists as Co<SUP>2+</SUP>/Co<SUP>3+</SUP>, while Fe exists as a mixture of Fe<SUP>0</SUP> (metallic) and Fe<SUP>2+</SUP>. The XMCD studies confirm these results and reveal that Co-ions are responsible for the room temperature ferromagnetism (RTFM) in the system, while at Fe L<SUB>3,2</SUB>-edge it shows a diamagnetic behavior.

요크셔종에 대한 경제형질의 유전모수 추정

송광림,김병우,김시동,최진성,김명직,이정규 한국동물자원과학회 2002 한국축산학회지 Vol.44 No.5

본 연구는 1994년부터 2000년까지 축산기술연구소 종축개량부에서 사육된 Yorkshire종 돼지 2,111두의 자료를 근거로 하여 주요 경제형질인 일당증체량, 90㎏ 도달 일령, 등지방두께에 대한 유전력, 유전상관, 표현형상관을 추정하기 위하여 MTDFREML Package에서 Animal model를 이용하여 분석하였다. 본 연구에서 얻은 결과를 요약하면 다음과 같다. 1. 분석한 돼지의 주요 경제형질의 평균치는 등지방두께가 1,476±0,241㎝, 일당증체량이 0.871±0.124㎏, 90㎏ 도달 일령이 145.397±11.718일 이었다. 2. 분석한 형질들의 유전력은 등지방두께가 0.55, 일당증체량이 0.55, 90㎏ 도달 일령이 0.56으로 전체적으로 고도의 유전력을 보였다. 3. 분석한 형질들의 유전상관은 일당증체량과 90㎏ 도달 일령에서는 -0.82, 일당증체량과 등지방두께 에서는 0.10, 90㎏ 도달 일령과 등지방두께 사이에서는 -0.25로 나타났다. 조사된 형질들의 표현형상관은 일당증체량과 90㎏ 도달 일령에서는 -0.77, 일당증체량과 등지방두께 에서는 0.02, 90㎏ 도달 일령과 등지방두께 사이에서는 -0.05로 나타났다. 등지방두께에 대한 일당증체량과 90㎏ 도달 일령사이의 표현형상관은 낮게 나타났지만 유전상관은 다소 높게 나타나 개량시 이점에 대하여 고려하여야 할 것이라 사료된다. 유전력에 있어서는 주요 경제형질 모두 고도의 유전력을 나타내어 적절한 선발 및 사양관리가 이루어진다면 Yorkshire종에 대한 유전적 개량량이 높을 것으로 사료된다. This study was conducted to estimate the heritabilities and genetic and phenotypic correlations among average daily gain, age at 90㎏ and backfat thickness in Yorkshire pigs. The data were obtained from 2,111 heads of Yorkshire tested at National Livestock Research Institute from May, 1994 to April, 2000. Genetic parameters were estimated with a multiple trait animal model by using DF-REML (Derivative-Free) REstricted Maximum Likelihood). The results obtained are summarized as follows; The means of traits studied were 0.871±0.124 ㎏ for average daily gain, 145.397±11.718 days for age at 90㎏ and 1,476±0,241 ㎝ for backfat thickness. The estimated heritabilities were 0.55 for average daily gain, 0.56 for age at 90㎏ and 0.55 for backfat thickness. The genetic correlation of average daily gain with age at 90㎏ and backfat thickness were -0.82, 0.10, respectively. The genetic correlation of age at 90㎏ with backfat thickness was -0.25. The phenotypic correlations of average daily gain(ADG) with age at 90㎏ and backfat thickness and age at 90㎏ with backfat thickness were -0.77, 0.02 and -0.05 respectively. Though phenotypic correlation of ADG and age at 90㎏ was low, breeding project should be carefully considered by high genetic correlation. High heritabilities on all economic traits were obtained. Therefore, it is considered that suitable selection and management is needed successful improvement.

무창육성돈사의 환기시스템에 따른 환기효율 평가

손준익,최홍림 한국동물자원과학회 2002 한국축산학회지 Vol.44 No.1

본 실험은 우리 나라의 양돈농가에서 노동력 절감이라는 이점 때문에 자돈사 및 분만사의 무창돈사는 일반농가에까지 보급되고 있으나, 육성·비육돈사에 있어서 무창돈사는 거의 전무한 실정으로 질병의 근원적인 차단 및 관리를 위하여 지금까지 회피되어 왔던 무창 육성·비육돈사의 활성화를 위하여 환기시스템을 자체적으로 고안하여 최적의 환기시스템을 여름철 및 겨울철로 구분하여 건축하였으며, 자체적으로 고안한 환기시스템의 성능을 평가하고자 겨울철 및 여름철로 구분하여 시험한 결과를 요약하면 다음과 같다. 1. 무창 육성·비육돈사에 있어서 돼지 생활공간(하부) 지점에서의 공기유속은 겨울철 최소환기 수준(1,440 ㎥/h)으로 하였을 때 0∼0.19 m/s 였으며, 여름철 최대환기 수준(24,000 ㎥/h)에서는 0.07∼0.42 m/s로 분포되어 여름철 및 겨울철의 무창돈사내 공기유속으로 보아 환기시스템이 우수하였다. 이상의 실험결과를 종합해 보면 무창 육성·비육사의 환기시스템은 여름철 때는 측벽을 통한 환기와 겨울철은 천장을 통한 환기시스템이 적합하다고 판단되었으며, 한쪽 측벽에 의한 배기시스템이라도 입기구는 양쪽 측벽을 통한 입기가 우수하다는 것을 알 수 있었다. An experiment was conducted to evaluate a ventilation system, which was devised to encourage farmers to use the enclosed growing and finishing pig housing system. A roof-air-entry ventilation system in winter and a side-wall-air-entry system in summer were evaluated. Air flow rate on the floor level which is the low part of pen and the living area of pigs in the enclosed growing and finishing pig house during winter was measured at 0 to 0.19 m/s at the minimum ventilation efficiency of 1,440 ㎥/h. During summer the air flow rate was detected at 0.07 to 0.42 m/s at the maximum bentilation efficiency of 24,000 ㎥/h. Therefore, it is concluded that the side-wall ventilation system is suitable for growing and finishing pigs in the enclosed house during the days of mid-summer and the roof-ventilation system was suitable during the coldest days of mid-winter. In addition, although the enclosed pig house has the system in which air exhausts through only one side wall, air should enter through both-side walls for the better ventilation performance.

Identifying and Exploring Significant Genomic Regions Associated with Soybean Yield, Seed Fatty Acids, Protein and Oil

Christopher J Smallwood,Jason D Gillman,Arnold M Saxton,Hem S Bhandari,Phillip A Wadl,Benjamin D Fallen,David L Hyten,Qijian Song,Vincent R Pantalone 한국작물학회 2017 Journal of crop science and biotechnology Vol.20 No.4

Soybean [Glycine max (L.) Merrill] yield and seed fatty acids, protein, and oil content are important traits for which an improved understanding of significant genomic regions would be useful. To accomplish this, a soybean population consisting of 203 F5 derived recombinant inbred lines (RILs) was developed and genotyped with 11,633 polymorphic single nucleotide polymorphisms (SNPs). Each RIL was grown in a single plot at Knoxville, TN in 2010; followed by replicated, multi-location field trials in 2013 and 2014. The data from 2010, 2013, and 2014 were analyzed together in order to detect quantitative trait loci (QTL) for these traits, and 30 total QTLs were detected. Five QTLs are candidates for confirmed status and one QTL is a candidate for positional confirmation. Many of the genes with mutations in close proximity to the fatty acid QTLs are involved in biological processes for fatty acids and/or lipids and could be considered possible candidate genes. Similarly, genes with mutations in genomic regions near yield, protein, and oil QTLs were plentiful and may contribute to the variation observed in these traits. Except for yield and stearic acid, each trait displayed pleiotropic effects with other traits in this study. Notable are the pleiotropic effects for oleic and linolenic acid on chromosomes 9, 13, and 19. Overall, the findings from this research contribute new information to the genetic understanding of soybean yield and seed fatty acids, protein and oil content. This understanding will be useful in making trait improvements.