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Self-Polishing Behavior of Zinc-Based Copolymer with Different Monomer Composition
김병우,조남주,강태운,박현,이인원,전호환 한국고분자학회 2014 Macromolecular Research Vol.22 No.9
The zinc methacrylate copolymers with various monomer compositions were prepared for investigatingthe effect of zinc methacrylate (ZMA), 2-methoxyethyl acrylate (2-MTA) contents and compositions of ethyl acrylate(EA) and methyl methacrylate (MMA) as hydrophobic monomers on self-polishing behavior. The effect ofmolecular weight of the self-polishing copolymer (SPC) was also investigated. The characterizations of copolymerswere performed by Fourier transform infrared spectroscopy (FTIR), 1H nuclear magnetic resonance (NMR), gel permeationchromatography (GPC), and differential scanning calorimetry (DSC). The leaching rate of SPC was determinedfrom the reduction of dry film thickness after seawater immersion in a dynamic condition. The experimental resultsindicate the leaching rate of SPC can be controlled by monomer composition and molecular weight.
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MCM 단백질 발현억제 물질인 자단향 메탄올 추출물의 항암활성
김병우,서은진,홍윤경,이은우,김영희,권현주,윤희정 대한암예방학회 2008 Journal of cancer prevention Vol.13 No.1
The MCM protein family has six highly conserved subunits, MCM2 to 7, and is essential for initiation and elongation of DNA replication in all eukaryotes. Deregulation of the MCM function and expression resulted in cells undergoing tumorigenesis. Therefore, these proteins are potential diagnostic markers for cancer and promising targets for anticancer drug development. To screen lead compounds, which inhibit expression of MCM proteins, several medicinal plants were examined. Among them Pterocarpus santalinus was selected as candidate. Methanolic extract of Pterocarpus santalinus (MEPS) inhibited MCM expression in a dose-dependent manner (40∼60μg/ml). MEPS showed cytotoxic and antiproliferative activity against six human cancer cells tested such as HeLa, HT29, T24, HepG2, A549 and Jurkat E6-1. A 35% of abdomen tumor width reduction was observed in vivo experiment using C57BL/6 mouse bearing Sarcoma 180 cells after treatment of MEPS for 16 days. Oligonucleotide microarray analysis identified 69 up-regulated genes and 79 down-regulated genes in HeLa cells after MEPS treatment. The deregulated genes were involved in various biological process including cell cycle regulation and cell proliferation, signal transduction, apoptosis. (Cancer Prev Res 13, 54-61, 2008)
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김병우 충북연구원 2010 지역정책연구 Vol.21 No.1
As evident from the results of shift-share analysis, the effect of regional-share effect that expresses the potential of job creation in ChungBuk region is highest among 5 benchmarking regions, ChungBuk region seems to have relatively high potential competence for employment in manufacturing. In economic model, there occurs positive correlation between technical progress and employment both in aggregate production and search and matching model. Structural VAR estimation and variance decomposition results imply 1) the explanatory power of GRDP on ChungBuk employment is higher than that of GDP, 2) for regional job creation, it is necessary for regional economy to grow firstly. -
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미생물막 유동층반응기 내 탄소원의 특성과 기질전환 모델
김병우,김병규,이강석 한국화학공학회 1984 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.22 No.3
유동층 미생물막 반응기 내 합성폐수의 脫窒化에 있어 基質인 탄소원의 특성이 미생물막의 두께에 미치는 영향을 검토하기 위하여 회분배양 실험을 하였다. 各種 탄소원에 대한 미생물의 대사작용을 분석한 결과 메탄올이 효율적인 탄소원으로서의 특성을 가지고 있음이 밝혀졌다. 그리고 이미 제시된 여러 반응기 모델은 반응기 설계시 운전조건에 따라 변하는 매개변수들이 많아 Rodrigues[1]가 제시한 방식에 따라 설계식을 단순화시킨 결과 다음과 같은 관계식을 얻었다. √C₁-√C_o=Kt, K=(1-ε)√2kD_b/2δ 본 실험결과로부터 계산된 반응기 조업변수 K의 값은 0.007이었다. A batch culture was done to investigate the effect of carbon sources on the bacterial film growth and denitrification. From an analysis of the metabolism characteristics of the denitrifying bacteria in each medium, methanol was found to be the most effective C-source. Existing design models of the fluidized biofilm reactors containing parameters dependent on the operational condition, were simplified according to the Rodrigues' proposal as follows. √C₁-√C_o=Kt, K=(1-ε)√2kD_b/2δ From the results of experiments, the performance parameter K was 0.007.
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