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MgB₄O7 熱螢光體의 특성과 低에너지 X線의 線量測定
김영국,손인호,설정식,채건식,노경석 慶南大學校 附設 基礎科學硏究所 1997 硏究論文集 Vol.11 No.-
To develope the thermoluminescent radiation sensors and low energy X-ray of dosimetry. The TL phosphors of MgB₄O7 are prepared and their physical characteristics are investigated. MgB₄O7 : Tb. Tm. Dy. La. Ho. and Nd phosphors have been prepared by sintering around 580℃ for 2 hours followed by flowing Ar gas. Ar gas. Activation energy and kinetic order of main peak of glow curve were studied by two methods peak shape method and initial rise method. By these methods, the estimated activation energies were 0.76±0.02eV(Tb doped). 0.94±0.03(Tm doped). 0.72±0.02 (Dy doped). respectively. The activation energy frequency factor and kinetic order of thermoluminescent process for each TL phosphors are measured by analyzing the glow curve by initial rise. peak shape. different heating rate. isothermal decay method. And The emission spectra of TL phosphors are also measured. The TL phosphors prepared in this work may be utilized to radiation sensor elements becaue of their high sensitivity to low energy X-ray.
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김재성,조문준,박경덕,설종구 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2
Wilms' tumor is the paradigm for multimodal treatment of a pediatric malignant solid tumor. Developments in surgical techniques and postoperative care, recognition of the sensitivity of Wilms' tumor to irradiation, and the availability of several active chemotherapeutic agents led to a dramatic change in the prognosis for most patients with this once uniformly lethal malignancy. This article presents four cases of Wilms' tumor managed at Chungnam National University Hospital and reviews current treatment recommendations for patients with Wilms' tumor, based upon the results of the National Wilms' Tumor Studies.
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Mg₂SiO₄: Tb, Nd, Dy 열형광선량계에서 활성제 농도가 Glow Curve에 미치는 영향
노경석,채근식,오재근,김영국,이은숙,설정식,손인호 慶南大學校 附設 基礎科學硏究所 1996 硏究論文集 Vol.8 No.-
The Mg₂SiO₄: Tb, Nd, Dy thermoluminescent phospher has been prepared by sintering Mg₂SiO₄after doping the transition elements Tb, Nd and Dy. The heating rate is 10℃/sec at this thermoluminescent phospher are heated. From the results of this study, the following conclusions were obtained. The maximum peaks are found in the measured Mg₂SiO₄: Tb, Nd, Dy, and TL glow curve at 289℃, 252℃ and 220℃ when the 1wt.% ∼ 5wt.%. Glow curve of TLD increased TL intensity and temperature of peak appears to the high temperature when the heating rate is 10℃/sec∼25℃/sec. The activation energy of the main peak has been estimated by the peak shape method. The estimated activation energies are 1.26 eV, 0.53 eV and 0.80 eV respectively. The thermoluminiscence process in Mg₂SiO₄: Tb, Nd, Dy are found to the 2nd order when the main peak of the glow curve is analyzed by peak shape method. The Mg₂SiO₄: Tb thermoluminescent phosphor is the most sensitive to X-rays among the other materials. The dose responses of Mg₂SiO₄: Tb, Dy TLD are linear up to intensity of X-ray.
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Panax ginseng Protects Against Global Ischemia Injury in Rat Hippocampus
Kim, Young-Ock,Kim, Hak-Jae,Kim, Geum-Soog,Park, Ho-Gi,Lim, Sang-Jong,Seong, Nak-Sul,Ham, Yung-Woon,Lee, Sung-Dong,Jang, Ki-Hyo,Jung, Kyung-Hee,Chung, Joo-Ho,Kang, Soon-Ah The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.1
Based on the use of Panax ginseng C.A. Meyer (Family Araliaceae) for the treatment of stroke in traditional Korean medicine, the present study was carried out to evaluate neuroprotective effects of P. ginseng after transient global cerebral ischemia using the four-vessel occlusion rat model. Nissl staining, lipid peroxidation (malondialdehyde [MDA] formation), and activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) of rat brain were assessed. Ethanolic P. ginseng extract (200 mg/kg, i.p.) significantly protected CA1 neurons against 10 minutes of transient forebrain ischemia as demonstrated by measuring the density of neuronal cells. P. ginseng also significantly decreased the level of MDA and increased the expression of GPx and SOD. These results suggest that P. ginseng might be neuroprotective against cerebral ischemia-induced injury in rat brain by decreasing lipid peroxides and increasing the expression of GPx and SOD.
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Kim, Sul Kyung,Gupta, Moumita,Lee, Hyung-il Elsevier 2018 Sensors and actuators. B Chemical Vol.257 No.-
<P><B>Abstract</B></P> <P>A recyclable polymeric film was designed and prepared for the consecutive colorimetric detection of cysteine and mercury (II) ions. A target random terpolymer (P1) of <I>N</I>,<I>N</I>-dimethylacrylamide (DMA), (<I>E</I>)-2-((4-((4-formylphenyl)diazenyl)phenyl)(methyl)amino) ethyl acrylate (FPDEA, M1), and <I>N</I>-(4-benzoylphenyl)acrylamide (BPAm) was synthesized via free radical polymerization (FRP). The average molecular weight (M<SUB>n</SUB>) of [p(DMA-co-FPDEA-co-BPAm), P1] was 39,300, and the molecular weight distribution (M<SUB>w</SUB>/M<SUB>n</SUB>) was 1.6. P1 exhibited excellent sensitivity and selectivity towards cysteine in the aqueous media. A simple reaction between the aldehyde groups of P1 and cysteine led to the formation of P2 with five-membered rings, accompanied by the color change from orange to yellow. The <I>in situ</I> generated P2 after cysteine detection responded selectively to mercury (II) ions in which the five-membered rings of P2 dissociated into P1 with CHO groups and cysteine. For further film study to demonstrate the reversiblity of the system, P1 was immobilized on a quartz slide by the spin-coating, followed by the exposure to UV light. The resulting film was successfully used for the consecutive colorimetric detection of cysteine and mercury (II) ions, demonstrating its reusability even after multiple cycles.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Azoaniline-based polymeric probe was synthesized and characterized. </LI> <LI> Selective and colorimetric sensing for cysteine in water. </LI> <LI> Excellent selectivity and colorimetric sensing for mercury(II) ions in water. </LI> <LI> Consecutive sensing by using a single component. </LI> <LI> Reusable polymeric film for detection of cysteine and mercury (II) ions. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P> <P>Aldehyde-functionalized azo-containing polymer was synthesized and characterized. Consecutive sensing of cysteine and mercury (II) ions was checked in water with high selectivity and sensitivity. After immobilizing the polymer on the surface, the successive colorimetric detection of cysteine and mercury (II) ions was repeatable over several cycles, demonstrating the whole system to be reversible, and this polymeric film can be reused.</P>
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SUL, Ok-Joo,KIM, Jin-Chun,KYUNG, Tae-Wook,KIM, Hye-Jin,KIM, Youn-Young,KIM, Song-Hee,KIM, Ji-Soon,CHOI, Hye-Seon Japan Society for Bioscience, Biotechnology, and A 2010 Bioscience, Biotechnology, and Biochemistry Vol.74 No.11
<P>Gold nanoparticles inhibited osteoclast (OC) formation induced by the receptor activator of nuclear factor-κB ligand (RANKL) in bone marrow-derived macrophages (BMMs). This was accompanied by a decreased level of tartrate-resistant alkaline phosphatase (TRAP) and less activation of nuclear factor (NF)-κB. The nanoparticles also reduced the production of reactive oxygen species (ROS) in response to RANKL and upregulated RANKL-induced glutathione peroxidase-1 (Gpx-1), suggesting a role as an antioxidant in the BMM. The inhibitory effects on OC formation might have been due to elevated defense against oxidative stress.</P>
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Kim, Kyung-Min,Kim, Chang-Kil,Han, Jeung-Sul The Korean Society of Plant Biotechnology 2010 Plant biotechnology reports Vol.4 No.2
An efficient plant regeneration system has been developed for figleaf gourd (Cucurbita ficifolia Bouch$\'{e}$), which is exclusively used as a rootstock for cucumber. The protocol is based on results obtained from a series of culture experiments involving different parts of the cotyledons and various media. The culture of cotyledon explants was critical for the enhancement of shoot regeneration frequency. The lower parts of the cotyledon excised at the plumule base were found to display a markedly enhanced production of adventitious shoots compared to other cotyledon regions. Culture in silver nitrate-supplemented Murashige and Skoog (MS) medium was not beneficial for shoot regeneration and suppressed root regeneration. Efficient shoot regeneration was obtained on MS medium containing 1.0 $mg\;l^{-1}$ zeatin and 0.1 $mg\;l^{-1}$ indole-3-acetic acid. Regenerated shoots successfully elongated and rooted in medium containing 0.1 $mg\;l^{-1}$ 1-naphthalene-acetic acid after 10-15 days of subculturing. The plantlets were satisfactorily acclimatized in a greenhouse and grew into normal plants without any morphological alterations.
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