골분을 이용한 구리 흡착 첨착

김은정,박정훈,김정섭,유현철,이봉섭,곽명화,우성훈,박승조 東亞大學校 環境問題硏究所 2005 硏究報告 Vol.27 No.1

Spent pig bone was consist of hydroxyapatite. And then we thought that it have a possibility as a adsorbent. The preparation of bone char prepared from spent pig bone in this study. We study on the recycling possibility as a adsorbent is able to adsorb copper ion from their single aqueous solutions. The results are summarized as follows. Bone char that prepared from spent pig bone at 105, 400, 700℃. The adsorption removal efficiency of copper ion onto bone char as adsorbent was above 90% for 15 hours. Increase in the initial pH of the copper ion solution result in an increase in the copper ion uptake per unit weight of the adsorbent. Freundlich isotherm model was found to be applicable for the experiment data of copper ion. The results showed that spent pig bone can be used for the absorption of the copper ion.

아스팔트 콘크리트의 고온변형저항 특성 측정방법 개발

김광우,이문섭,김중렬,이순제 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

본 연구는 정하중하에서 아스팔트 혼합물의 소성변형 저항특성을 측정할 수 있는 새로운 시험방법을 개발하기 위하여 수행되었다. 2가지 골재(편마암, 화강암)와 6가지 아스팔트(일반아스팔트, 5가지 개질 아스팔트)를 사용하여 총 12개의 밀입도 혼합물을 제작하였다. 마샬 배합설계를 통해 최적아스팔트 함량을 구하고, 결정된 최적아스팔트 함량으로 마샬공시체(S=10 cm)와 자이레토리 공시체(S=15cm)를 제작하여 마샬안정도시험, 휠 트랙킹 시험, 개발된 김테스트(Kim -test)를 수행하였다. 김테스트는 공시체와 하중봉을 지지할 수 있는 김시험장치(Kim tester)를 이용하여 하단이 반경(r) 0.5 또는 1.0cm로 원형절삭한 직경(D) 3cm, 4cm의 하중봉을 사용한다. 또한 재하는 마샬 하중재하 장치를 사용하여 공시체를 60℃ 수조에 30분동안 수침시킨 후 실시되었다. 정하중은 공시체의 직경방향이 아닌 축 방향으로 50 mm/min가 가해졌고, 최대하중(P_max)과 수직변형(y)이 측정되었다. 마샬안정도시험과 간접인장강도시험에서 얻어지는 것과 유사한 곡선이 각각의 시험에서 얻어졌다. 강도값은 P_max, r, y 및 H(=D-2r)을 이용한 K_D=4P_max/π(H+2√(2ry-y^2))^2식을 통하여 계산하였고, 이를 변형강도(kgf/㎠)로 정의하였다. 실험결과, 공시체 직경이나 골재종류보다는 하중봉과 하중봉 하단의 원형처리 여부가 K_D와 P_max 값에 영향을 미치는 것으로 나타났다. 통계분석결과에서 K_D가 소성변형 깊이와 동적 안정도에 높은 상관성을 보였다. 향후 연구를 통해 K_D의 유효성이 검증된다면, Kim-test는 아스팔트 혼합물의 소성변형 저항성을 판단할 수 있는 시험방법으로 사용될 수 있을 것이다. This study dealt with developing a new approach for finding properties which might represent rut resistance characteristics of asphalt mixture under static loading. Two aggregates, a normal asphalt (pen 60-70) and 5 PMAs were used in preparation of 12 dense-grade mixtures. Marshall mix design was used in determination of the optimum asphalt content (OAC) and each mixture at the OAC was prepared for a newly-developed Kim test on Marshall specimen (S=10 cm) and gyratory specimen (S=15cm), and for wheel tracking test. Kim test used Marshall loading frame and the specimen was conditioned for 30min at 60℃ before loading through Kim tester, and apparatus consisting of a loading column and a specimen and column holder. Diameter (D) of column was 3cm and 4cm with each column having different radius (r) of round cut at the bottom. The static load was applied at 50mm/min in axial direction of the specimen, not in diameteral direction, and the maximum load (P_max) and vertical deformation (y) at the maximum load point were measured. A curve, similar to the one from a Marshall test or static indirect tensile strength test was obtained from each test. A strength value was calculated based on the P_max, H(=D-2r). r and y by using the equation K_D=4P_max/π(H+2√(2ry-y^2))^2 and is defined as deformation strength (kgf/㎠). The values of P_max/y and K_I=K-D/y were also calculated to see if these have any correlation with rutting. In general, D and r were significant factors affecting K_D, while specimen size was not. The statistical analyses results showed the K_D had the best correlation with rut depth and dynamic stability. The next best correlation was found from P_max which was followed by P_max/y and K_I in order. Therefore, K_D can be used for selecting the highly resistable asphalt mixture against permanent deformation.

Suppressive effects of three diketopiperzines from marine-derived bacteria on TGFBIp-mediated septic responese in human endothelial cells and mice

( Byeongjin Jung ),( Sae Kwang Ku ),( Ming Gao ),( Kyung Min Kim ),( Min Su Han ),( Hyukjae Choi ),( Jong Sup Bae ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-

Diketopiperazine is a naturally occurring cyclic dipeptide found from diverse living organisma. The com-pounds in this structure class have been known with a broad spectrum of bioactivities including anti-inflamma-tory activities. Transforming growth factor β-induced protein (TGFBIp) is an extracellular matrix protein whose expression in several cell types is greatly increased by TGB- β. TGFBIp is released by human umbilical vein endothelica cells and functions as a mediator of experi-mental sepsis. Here, three (1-3) of diketopiperazines were isolated from two strains of marine-derived bacteria and we hypothesized that 1-3 could reduce TGFBIp-mediated severe inflammatory responses in human endothelial cells and mice. Here, we investigated the anti-septic effects and underlying mechanisms of 1-3 effectively inhibited lipopolysac-charide-induced release of TGFBIp and suppressed TGFBIp-mediated septic responses. In addition, 1-3 sup-pressed cecal ligation and puncture (CLP)-induced sepsis lethality and pulmonary injury. In conclusion, 1-3 sup-pressed TGFBIp-mediated and CLP-induced septic response. Therefore, 1-3 could be a potential therapeutic agent for treatment of various severe vascular inflamma-tory diseases inhibition of the TGFBIp signaling pathway.

토양처리용 천연물제초제 개발을 위한 생물검정법 개선

김재덕(Jae Deong Kim),황현진(Hyun Jin Hwang),서보람(Bo Ram Seo),최정섭(Jung Sup Choi),김진석(Jin Seog Kim) 韓國雜草學會 2011 Weed&Turfgrass Science Vol.31 No.3

본 연구는 토양처리용 천연물 제초제의 개발을 보다 신속하게 효율적으로 진행하기 위한 방안으로서 실용적인 입장에서 보다 개선된 검정법을 확립하기 위해 수행되었다. 검정하고자 하는 화합물의 량이 50㎎ 이상 충분할 경우, 잡초 4초종(피, 바랭이, 자귀풀, 어저귀)이 파종된 50㎠ 토양 표면적을 가진 폿트에서 온실검정을 함으로서 기존의 방법(토양 표면적이 350㎠인 폿트 이용)에 비해 약제 소요량을 78배 줄일 수 있었다. 이때 검정초기 처리농도는 10,000㎍ mL<;SUP>;-1<;/SUP>; 내외로 하는 것이 적당하였다. 한편 검정용 시료의 량이 10㎎ 이하로서 미량일 경우는 6 well plate를 이용하되 각 well에 밭토양을 담고 4가지 초종을 파종한 다음 실내에서 제초활성을 검정하는 방법이 추천될 수 있었다. 이는 기존의 방법(토양 표면적이 350㎠인 폿트 이용)에 비해 약제 소요량 및 처리용액 부피를 14배 가까이 줄일 수 있었고 실제에 가까운 데이터를 확보할 수 있어 보다 빠른 속도로 천연물 제초제를 개발하는데 도움이 될 것으로 판단되었다. This study was carried out to establish an improved bioassay system on the side of practicality, pre-emergence bioassay which is more effective in developing soil application natural herbicides. A miniaturized method which have a 50 cm² of soil surface area and was efficient by 7 times compared to the existing soil application assay (350 cm² of soil surface area) was established, in which four weed species (Echinochloa crus-galli, Digitaria sanguinalis, Aeschynomene indica, and Abutilon theophrasti) were planted and grown in greenhouse. This would be applicable when the amount of screening compound is much more than 50 mg. The initial application rate was desirable at 10,000 μg mL-1. On the other hand, the 6 well plate assay which has 4 weed species in each well containing upland soil and could be conducted in growth chamber, was established. This assay was resulted in minimizing in level of 1/14 test volume and 1/14 amounts of test compound to the conventional method that has been used for screening of synthetic compounds in KRICT, and applicable for the small amount of test compound (less than 10 mg). Therefore, the improved bioassays established in this study would be helpful for a rapid and efficient development of soil application natural herbicides.

딤플을 적용한 평판에 대한 항력 감소 연구

백부근(Bu-Geun Paik),편영식(Young-Sik Pyun),김준형(Jun-Hyung Kim),김경열(Kyung-Youl Kim),김기섭(Kim1 ?Ki-Sup),정철민(Chul-Min Jung),김찬기(Chan-Ki Kim) 대한조선학회 2012 大韓造船學會 論文集 Vol.49 No.4

고령토로부터 합성한 제올라이트 A 의 열처리에 의한 특성변화

김면섭,정순용 한국화학공학회 1984 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.22 No.1

하동지방의 담홍색 고령토를 수산화나트륨수용액으로 반응시켜 합성한 제올라이트A를 400℃에서 900℃까지 열처리하여 그 특성변화와 이온교환성에 대해서 연구하여 다음과 같은 결과를 얻었다. 제올라이트A는 800℃에서 결정이 파괴되어 900℃에서는 nepheline이 생성됨을 알았다. 400℃와 750℃사이에서 열처리한 제올라이트A의 흡수성은 변화가 없었으나, 800℃ 및 900℃로 열처리한 제올라이트A는 흡수능이 거의 없음을 알 수 있었다. Ag^+ - Na^+의 이온교환반응의 경우는 400∼750℃로 열처리하나 제올라이트A는 이온교환성이 거의 일정하였으나 Mg^(2+) - Na^+의 이온교환반응일 경우에는 400℃에서 750℃까지 열처리온도가 증가할수록 이온교환성이 조금씩 감소하는 경향을 보였다. 또한 800℃ 및 900℃로 열처리한 제올라이트A는 이온교환이 거의 일어나지 않음을 알 수 있었다. Ag^+ - Na^+와 Mg^(2+) - Na^+의 이온교환반응의 실험값으로부터 표준 Gibbs자유에너지, 엔탈피, 엔트로피를 계산하였다. Synthetic zeolite A prepared from Hadong kaolin in sodium hydroxide solution was calcined between 400 and 900℃. Changes of ion exchange properties and structure during the thermal treatment between 400 and 900℃ were studied. As the synthesized zeolite A was treated at 800℃, the structure was partially destroyed, whereas at 900℃, nepheline type structure was appeared. The water adsorption capacity on zeolite A treated between 400 and 750℃ was almost constant, but that was only trace amount at 800 and 900℃. When zeolite A was heated from 400 to 750℃, the ion exchange properties were almost constant for the Ag^+-Na^+ system, but slowly decreased for the Mg^(2+)-Na^+ system. At 800 or 900℃, the ion exchange properties were negligible. From the experimental data at ion exchange reaction in the cation system of Ag^+-Na^+and Mg^(2+)-Na^+ Gibbs free energy, enthalph, and entropy were calculated.

Spectral-Domain 광 계측을 위한 CCD 이미지 센서 드라이버 제작

김훈섭,이정렬,엄진섭 江原大學校 産業技術硏究所 2007 産業技術硏究 Vol.27 No.B

This paper presents Spectral-Domain optical measurement system using self-fabricated CCD sensor driver. The light source is a high brightness white LED and the detector is a 2048 array typed CCD image sensor. I have fabricated the CCD sensor driver to generate four pulse signals, which are the CCD-driving pulses. Using this Spectral Domain optical measurement system, the distance value between the reference mirror and the sample mirror can be obtained successfully.

동남아시아 지역 학습자를 위한 한국어 읽기 교육의 실제

김중섭 경희대학교 언어연구소 2002 언어연구 Vol.19 No.-

This research investigates effective methods in teaching Korean as a second/foreign language to learners in East Asian regions through the presentation of reading lessons. It is a common view that reading is an important measure in teaching language especially to a population less exposed to the spoken and listening component of the target language. According to recent survey studies, despite the time and effort allotted to teaching Korean through reading lessons, based on learners' cognitive processing and comprehension are uncommon. Therefore, this study proposes the importance of a well-designed lesson that stimulates learners' interests through true comprehension of reading matter in the target language Korean, especially in East-Asian regions. In addition, it proposes that Korean reading lessons should provide more interesting activities that transfer knowledge from other languages that learners bring into the Korean as a second/foreign language acquisition environment. (Kyung Hee University)

제Ⅱ형 당뇨병 환자들에게 있어서 걷기, 뛰기 운동이 혈압 및 심박수 변화에 미치는 영향

김갑구,이정섭,이재우,이정탁,최석립 대구보건대학 2002 대구보건대학 論文集 Vol.22 No.-

Result of analysis of walking and running training to 50-60yrs female non-insulin depentent diabetic patients presents next; Blood pressure of constriction period presents, based on training type, high during the training but is reduced during the recovery period. Analysis of heart rate based on training type presents high during the training but is reduced recovery period. In the result Exercise prescription programs for the non-insulin-depentent diabetic patients are required to maintain their Blood pressure and heart rate.

익상구개와에 발생한 악성 섬유조직구종 1예

홍정표,김인섭,김문석,윤주헌 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.9