http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Anti-Proliferative Effects of Estrogen Receptor-Modulating Compounds Isolated from Rheum palmatum
Kang, Se-Chan,Lee, Chang-Min,Choung, Eui-Su,Bak, Jong-Phil,Bae, Jong-Jin,Yoo, Hyun-Sook,Kwak, Jong-Hwan,Zee, Ok-Pyo 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.6
The Rheum palmatum L., a traditional medicine in Korea, was screened for their estrogenic activity in a recombinant yeast system with a human estrogen receptor (ER) expression plasmid and a reporter plasmid used in a previous study. The $EC_{50}$ values of the n-hexane, dichloromethane, ethyl acetate, n-butanol, and water fractions of the methanolic extract of R. palmatum in the yeast-based estrogenicity assay system were 0.145, 0.093, 0.125, 1.459, $2.853\;{\mu}g/mL$, respectively, with marked estrogenic activity in the dichloromethane fraction. Using an activity-guided fractionation approach, five known anthraquinones, chrysophanol (1), physcion (2), emodin (3), aloe-emodin (4) and rhein (5), were isolated from the dichloromethane fraction. Compound 3 had the highest estrogenic relative potency (RP, 17bestradiol = 1.00) ($6.3{\times}10^{-2}$), followed by compound 4 ($3.8{\times}10^{-3}$), compound 5 ($2.6{\times}10^{-4}$), and compound 1 ($2.1{\times}10^{-4}$). Also, compound 3 and fraction 3 (which contained compound 3) of the dichloromethane fraction of R. palmatum showed strong cytotoxicity in both ER-positive (MCF-7) and -negative (MDA-MB-231) breast cancer cell lines.
Kang, Ju-Sung,Hong, Seok-Hie,Lee, Sang-Jin,Yi, Ok-Yeon,Park, Choon-Sik,Lim, Jong-In Electronics and Telecommunications Research Instit 2001 ETRI Journal Vol.23 No.4
We examine the diffusion layers of some block ciphers referred to as substitution-permutation networks. We investigate the practical and provable security of these diffusion layers against differential and linear cryptanalysis. First, in terms of practical security, we show that the minimum number of differentially active S-boxes and that of linearly active S-boxes are generally not identical and propose some special conditions in which those are identical. We also study the optimal diffusion effect for some diffusion layers according to their constraints. Second, we obtain the results that the consecutive two rounds of SPN structure provide provable security against differential and linear cryptanalysis, i.e., we prove that the probability of each differential (resp. linear hull) of the consecutive two rounds of SPN structure with a maximal diffusion layer is bounded by $p^n(resp.q^n)$ and that of each differential (resp. linear hull) of the SDS function with a semi-maximal diffusion layer is bounded by $p^{n-1}(resp. q^{n-1})$, where p and q are maximum differential and linear probabilities of the substitution layer, respectively.
Evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities
Kang, Se Chan,Lee, Chang Min,Choi, Han,Lee, Jae Hyun,Oh, Joa Sub,Kwak, Jong Hwan,Zee, Ok Pyo Heyden & Son 2006 Phytotherapy research Vol.20 No.11
<P>Herb extracts commercially used in Asia were screened for their estrogenic activity with a recombinant yeast system with both a human estrogen receptor (ER) expression plasmid and a reporter plasmid. Pueraria lobata (flower) had the highest estrogenic relative potency (RP, 17-estradiol = 1.00) (7.8e-3) (RP for + control), followed by Amomum xanthioides (1.3e-3), Glycyrrhiza uralensis, Zingiber officinale, Rheum palmatum, Curcuma aromatica, Eriobotrya japonica, Sophora flavescens, Anemarrhena asphodeloides, Polygonum multiflorum and Pueraria lobata (root) (9.5e-4–1.0e-4), and Prunus persica, Lycoppus lucidus and Adenophora stricta (9.0e-5–8.0e-5). In the antiproliferative assay, five human cancer cell lines representing different tissues (breast, lung and ovary) were used. Eriobotrya japonica showed strong cytotoxicity in ER-negative breast cancer (MDA-MB-231), cervix epitheloid (HeLa) and lung (A549) carcinoma cell lines. Copyright © 2006 John Wiley & Sons, Ltd.</P>
Ureteral polypoid endometriosis causing hydroureteronephrosis
( Ok Ji Hoon ),( Cha Moon Seok ),( Han Myoung Seok ),( Cho Yeon Jean ),( Kang Ji Young ),( Bae Jong Woon ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-
A 42-year-old nulliparous woman visited our hospital due to the left hydronephrosis which had been found during her regular check-up. Abdominal ultrasonography revealed the left hydroureteronephrosis and about 6-cm intramural uterine fibroid locating at the left lateral wall. She had mild dysmenorrhea during her periods but did not need to take a pill. Her pelvic examination revealed no evidence of the pelvic endometriosis. She underwent the laparoscopic surgery to remove the fibroid and find the reason of the hydronephrosis. The uterine fibroid had no relationship with the left hydronephrosis, but there was an adhesive peritoneal endometriotic lesion at the left pelvic brim. After dissection of the left retroperitoneal space, we found the swollen portion of the ureter beneath the adhesive peritoneum, which length was about 3cm. We performed the segmental resection of the swollen ureter and the ureteroureterostomy, After procedure, the resected specimen showed a 3-cm polypoid mass inside the lumen. Histologically, the mass was ureteral endometriosis. The postoperative course was uneventful. Ureteral polypoid endometriosis causing hydroureteronephrosis is rare. Hence, we report this case.