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      • Fabrication and thermoelectric properties of c-axis-aligned Bi<sub>0.5</sub>Sb<sub>1.5</sub>Te<sub>3</sub> with a high magnetic field

        Kim, D.H.,Kim, C.,Je, K.C.,Ha, G.H.,Kim, H. Elsevier Science 2011 ACTA MATERIALIA Vol.59 No.12

        We simultaneously investigated the effects of nanostructure and crystal alignment on the thermoelectric performance of polycrystalline Bi<SUB>0.5</SUB>Sb<SUB>1.5</SUB>Te<SUB>3</SUB>. An appropriate experimental procedure was devised for a sequential process of slip-casting under a 6T magnetic field for c-axis alignment and the use of a spark plasma sinter machine for sintering. Flake-shaped powders with particles less than 36μm in diameter stacked up with c-axis alignment under a 6T rotating magnetic field, while the same powders with particles less than 5μm in diameter showed a random orientation with no magnetic field. The c-axis-aligned material under the magnetic field showed an increase in hole mobility along the direction perpendicular to the c-axis that resulted in a 15% decrease in the electric resistivity, while the Seebeck coefficient and thermal conductivity remained unchanged; thus the figure of merit was improved by 15%. Theoretical evaluation of the electrical resistivity according to the c-axis alignment showed good agreement with the experimental results.

      • SCISCIESCOPUS

        Nodeless superconductivity in the noncentrosymmetric superconductor BiPd

        Yan, X B,Xu, Y,He, L P,Dong, J K,Cho, Hwanbeom,Peets, D C,Park, Je-Geun,Li, S Y IOP 2016 Superconductor science & technology Vol.29 No.6

        <P>We report low-temperature thermal conductivity measurements on high-quality single crystalline <I>α</I>-BiPd, a noncentrosymmetric superconductor with <I>T</I> <SUB>c</SUB>?≃?3.8 K. In zero magnetic field, the residual linear term <I>κ</I> <SUB>0</SUB>/<I>T</I> is absent, indicating a full gap and suggesting dominant singlet pairing. Consistent with this picture, <I>κ</I> <SUB>0</SUB>(<I>H</I>)/<I>T</I> shows weak field dependence in low field, but grows relatively fast in fields above 0.03 T (≃1/5<I>H</I> <SUB>c2</SUB>). Implications for the material’s disputed high-field behavior are discussed, and constraints are placed on the previously proposed scenarios.</P>

      • 자궁경부암 진단을 위한 세포진검사의 분석

        김기태,제구화,홍숙희,김현찬 인제대학교 1986 仁濟醫學 Vol.7 No.2

        1980년부터 1985년까지 총 9.838례의 세포진 검사를 실시하였으며 그 중 Class I이 49.8%, Class II가 46.3%. Class III가 1.8%, Class IV가 7.4%, Class V가 1.7%이었고, 조직검사상 세포진검사보다 중증 (false negative)을 보인 경우가 8.8%, 세포진검사보다 경증(false positive)을 보인 경우가 2.8%, 중증, 경증 각각 한 등급 이내(one histological degree: central zone)에 속했던 경우가 88.4%이었다. A total number of 9,838 Pap's smears which were screened for the detection of uterine cervical cancer, during the period of 6 years from January 1980 to December 1985, Pusan Paik Hospital, Inje Medical College, were analyzed. And clinical and histopathological studies were made on the cases of Pap. class III or over. The results obtained are summarized as follows: 1.Among the 9,838 cases, there are 4,900 cases of class I (normal), 49.8%, 4,555 cases of class II (benign atypia), 46.3%; 177 cases of class III(dysplasia), 1.8%; 37 cases of class IV (carcinoma in situ), 0.4%; and 157 cases of class V (invasive carcinoma), 1.6%. 2.The age distribution of the total number of 9,838 Pap. smear shows the highest frequency at the age groups of 31-35, which accounts for 2,493 cases (25.3%), and 4th and 5th decades account for 45.4%. 3.Abnormal cytologic finding over class III were found in 383 cases (3.9%) and the average prevalence rate of over class III and class V were 3.9% and 1.6%. 4.As to the clinico-pathological analysis of the Pap. smear class III or over, the followings are summarized; a. Age distribution and prevalence rate; 1) By the age group, the highest frequency is in the age of 46-50 and 238 cases (62%) belongs to the age 41 or over. 2) In class V, the highest frequency is found at the age of 46-50 and 94 cases (60%) are in the age 46 or over. 3.) The prevalence rate shows increasing tendency by progress of the age and the peak rate is 15.9% at the age of 61 or over. Also in class V, the peak rate is 9.8% at the age of 61 or over. b. The average age by the degree of Pap. smear; The average age is 42.9 years in mild dysplasia, 43.3 years in moderate dysplasia, 42.7 years in carcinoma in situ, and 47.9 years in invasive carcinoma. c. The age of marriage and parity; 1) The age of marriage shows the highest frequency at the age of 19-21, and 66.6% married before the age of 21. 2) In class IV, 61% married before the age of 21 and the mean age is 20.9. In class V, the mean age is 19.4 and 77.8% married before the age of 21. 3) The parity shows the highest frequency at the number of 3-4 and the average number is 3.6. d. Clinical symptoms and gross findings of the cervix; 1) The clinical symptoms are vaginal bleeding, leukorrhea, and pelvic pain in the order of frequency and those of class IV, class V are same. 2) The most frequent finding is erosion and the normal cervix is found in 7%. 3) In class IV, the most frequent finding is erosion and the normal cervix is found in 8%. In class V, the most frequent finding is also erosion and the normal cervix is found in 1.9%. e. Histopathologic examination, performed in 220 (57.4%) among 383 cases of class III or over, shows 51 cases of dysplasia, 33 cases of carcinoma in situ, 28 cases of microinvasive carcinoma, and 86 cases of invasive carcinoma. In compared with the Pap's smear,88.4% of 220 cases is belonged to within one histologic degree (central zone), and the false negative and false positive cytologic examination were 8.8% and 2.8% respectively.

      • Involvement of Nrf2-mediated heme oxygenase-1 expression in anti-inflammatory action of chitosan oligosaccharides through MAPK activation in murine macrophages

        Hyung, J.H.,Ahn, C.B.,IL Kim, B.,Kim, K.,Je, J.Y. North-Holland ; Elsevier Science Ltd 2016 european journal of pharmacology Vol.793 No.-

        <P>Chitosan and its derivatives have been reported to have anti-inflammatory effects in vitro and in vivo. It is also suggested that chitosan and its derivatives could be up-regulating heme oxygenase-1 (HO-1) in different models. However, the up-regulation of HO-1 by chitosan oligosaccharides (COS) remains unexplored in regard to anti-inflammatory action in lipopolysaccharide (LPS)-stimulated murine macrophages (RAW264.7 cells). Treatment with COS induced HO-1 expression in LPS-stimulated RAW264.7 cells, whereas the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) was decreased. Pretreatment with ZnPP, a HO-1 inhibitor, reduced the COS-mediated anti-inflammatory action. HO-1 induction is mediated by activating the nuclear translocation of NF-E2-related factor 2 (Nrf2) using COS. Moreover, COS increased the phosphorylation of extracellular signal regulated kinase (ERK1/2), c-Jun N-terminal kinase/stress-activated protein kinase (JNK), and p38 MAPK. However, specific inhibitors of ERK, JNK, and p38 reduced COS mediated nuclear translocation of Nrf2. Therefore, HO-1 induction also decreased in RAW264.7 cells. Collectively, COS exert an anti-inflammatory effect through Nrf2/MAPK-mediated HO-1 induction.</P>

      • KCI등재

        Octacosanol 섭취가 지구성 운동능력에 미치는 효과

        안의수,안병철,김완수,이한,제세영,박기문,이수원 한국운동영양학회 1999 Physical Activity and Nutrition (Phys Act Nutr) Vol.3 No.2

        The effect of octacosanol administration on endurance exercise capacity was invesgated. The subjects of this study were healthy-university students to test the effect of octacosanol. Octacosanol(medication group: n=15, athletic group: n=14, 300㎎/capsule, 4 capsules/day) or soy bean oil as placebo(n=15) was administered for 30 days and parameters related to the endurance exercise capacity were measured through incremental exercise testing to all-out before and after each treatment. Both VO_2max and all out time were significantly increased by administration of octacosanol as compared to placebo group(p<0.05). RQmax was significantly decreased in octacosanol as compared to placebo group(p<0.05). The administration of octacosanol had a trend of decrease as compared to placebo group in rating of perceived exertion(RPE) scale. Although the exact mechanism of effect caused by octacosanol administration is not known, it is possible that octacosanol increases the lipolysis and cardiacrespiratory function. From the results, it is suggested that the administration of octacosanol can be increased the endurance exercise capacity.

      • KCI등재SCIESCOPUS

        Cutting performance of nanocomposite Cr-C-N, Cr-Si-N and Cr-Si-C-N coated tools for micro end-milling operation

        Kim, M.W.,Tak, H.S.,Kang, M.C.,Kim, K.H.,Park, I.D.,Je, T.J. Elsevier 2009 Current Applied Physics Vol.9 No.2

        CrN-based multi-component coatings were deposited by a hybrid coating system combining arc ion plating (AIP) and a sputtering technique. In this paper, comparative studies on mechanical properties and cutting performance among Cr-C-N, Cr-Si-N and Cr-Si-C-N coatings were systematically conducted. Adding carbon and silicon atoms into CrN coatings had large effects on microstructural change and mechanical properties of CrN coatings by instrumental analyses such as XRD and HRTEM. The hardness value of Cr-Si-C-N coatings showed about 45GPa, while those of Cr-Si-N and Cr-C-N coatings were 34 and 23GPa, respectively. Cutting tests were carried out to evaluate the characteristics of micro cutting in a vertical machining center using an ultra-high-speed air turbine spindle. Consequently, the quaternary Cr-Si-C-N coated micro end-mill in dry machining showed good cutting performance under ultra-high-speed cutting conditions.

      • SCISCIESCOPUS

        Simulation and experimental studies of three-dimensional (3D) image reconstruction from insufficient sampling data based on compressed-sensing theory for potential applications to dental cone-beam CT

        Je, U.K.,Lee, M.S.,Cho, H.S.,Hong, D.K.,Park, Y.O.,Park, C.K.,Cho, H.M.,Choi, S.I.,Woo, T.H. Elsevier 2015 Nuclear Instruments & Methods in Physics Research. Vol.784 No.-

        <P><B>Abstract</B></P> <P>In practical applications of three-dimensional (3D) tomographic imaging, there are often challenges for image reconstruction from insufficient sampling data. In computed tomography (CT), for example, image reconstruction from sparse views and/or limited-angle (<360°) views would enable fast scanning with reduced imaging doses to the patient. In this study, we investigated and implemented a reconstruction algorithm based on the compressed-sensing (CS) theory, which exploits the sparseness of the gradient image with substantially high accuracy, for potential applications to low-dose, high-accurate dental cone-beam CT (CBCT). We performed systematic simulation works to investigate the image characteristics and also performed experimental works by applying the algorithm to a commercially-available dental CBCT system to demonstrate its effectiveness for image reconstruction in insufficient sampling problems. We successfully reconstructed CBCT images of superior accuracy from insufficient sampling data and evaluated the reconstruction quality quantitatively. Both simulation and experimental demonstrations of the CS-based reconstruction from insufficient data indicate that the CS-based algorithm can be applied directly to current dental CBCT systems for reducing the imaging doses and further improving the image quality.</P>

      • SCISCIESCOPUS

        Feasibility study for application of the compressed-sensing framework to interior computed tomography (ICT) for low-dose, high-accurate dental x-ray imaging

        Je, U.K.,Cho, H.M.,Cho, H.S.,Park, Y.O.,Park, C.K.,Lim, H.W.,Kim, K.S.,Kim, G.A.,Park, S.Y.,Woo, T.H.,Choi, S.I. Pergamon 2016 Radiation physics and chemistry Vol.119 No.-

        <P>In this paper, we propose a new/next-generation type of CT examinations, the so-called Interior Computed Tomography (ICT), which may presumably lead to dose reduction to the patient outside the target region-of-interest (ROI), in dental x-ray imaging. Here an x-ray beam from each projection position covers only a relatively small ROI containing a target of diagnosis from the examined structure, leading to imaging benefits such as decreasing scatters and system cost as well as reducing imaging dose. We considered the compressed-sensing (CS) framework, rather than common filtered-backprojection (FBP)-based algorithms, for more accurate ICT reconstruction. We implemented a CS-based ICT algorithm and performed a systematic simulation to investigate the imaging characteristics. Simulation conditions of two ROI ratios of 0.28 and 0.14 between the target and the whole phantom sizes and four projection numbers of 360, 180, 90, and 45 were tested. We successfully reconstructed ICT images of substantially high image quality by using the CS framework even with few-view projection data, still preserving sharp edges in the images. (C) 2015 Elsevier Ltd. All rights reserved.</P>

      • SCISCIESCOPUS

        Evaluation of high grid strip densities based on the moiré artifact analysis for quality assurance: Simulation and experiment

        Je, U.K.,Park, C.K.,Lim, H.W.,Cho, H.S.,Lee, D.Y.,Lee, H.W.,Kim, K.S.,Park, S.Y.,Kim, G.A.,Kang, S.Y.,Park, J.E.,Kim, W.S.,Jeon, D.H.,Woo, T.H. Elsevier BV * North-Holland 2017 Nuclear Instruments & Methods in Physics Research. Vol. No.

        <P><B>Abstract</B></P> <P>We have recently developed precise x-ray grids having strip densities in the range of 100 – 250 lines/inch by adopting the precision sawing process and carbon interspace material for the demands of specific x-ray imaging techniques. However, quality assurance in the grid manufacturing has not yet satisfactorily conducted because grid strips of a high strip density are often invisible through an x-ray nondestructive testing with a flat-panel detector of an ordinary pixel resolution (>100 μ m). In this work, we propose a useful method to evaluate actual grid strip densities over the Nyquist sampling rate based on the moiré artifact analysis. We performed a systematic simulation and experiment with several sample grids and a detector having a 143- μ m pixel resolution to verify the proposed quality assurance method. According to our results, the relative differences between the nominal and the evaluated grid strip densities were within 0.2% and 1.8% in the simulation and experiment, respectively, which demonstrates that the proposed method is viable with an ordinary detector having a moderate pixel resolution for quality assurance in grid manufacturing.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The precise carbon-interspaced antiscatter grids have been studied. </LI> <LI> It is proposed for a useful method to evaluate actual grid strip densities over the Nyquist sampling rate based on the moiré artifact analysis. </LI> <LI> The simulation and experimental results demonstrate that the proposed method is viable with an ordinary detector having a moderate pixel resolution (>100 μ m) for quality assurance in grid manufacturing. </LI> </UL> </P>

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