Wolff-Parkinson-White증후군의 임상상 및 전기생리학적 소견

안신기,이문형,장양수,오동진,최인석,하종원,임세중,김병옥,정남식,심원흠,조승연,김성순 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.9

栽培中 Tomato 果實의 窒酸鹽 및 亞窒酸鹽과 Ascorbic acid의 含量變化

尹衡植,申大休,崔載春,權重浩 慶北大學校 1982 論文集 Vol.33 No.-

This experiment was carried cut to investigate the relationship between nitrite and ascorbic acid contents in two kinds of tomato fruits namely, Bokwang, Suekwang, which were different distinguished in growth periods during culture. The results obtained were as follows. The nitrate content in two kinds of tomato fruits was relatively higher in Bokwang than Suekwang. It indicated high content as 5.8-12.5 ppm in flesh and 0.3-2.5 ppm in gelatinous pulp. In the beginning of growth period, nitrate content in flesh was 50-62.5ppm, and in the latter period was 21.3-38.4ppm. In the case of gelatinous pulp, it was decreased from 14.0-16.2ppm in the beginnig period to 9.3-10.7ppm in the latter period. In the case of nitite, there was no difference between two varieties. Nitrite content during growth increased from 0.15ppm to 0.21ppm in flesh and from 0.06ppm to 0.1ppm in gelatinous pulp. There was no difference between two varieties during growth in total ascorbic acid content and its concentration was 24.2-27.5mg in gelatinous pulp and was 13.8-18.6mg in flesh. The difference between two parts was about 10mg. In the changes of nitrate and nitrite content in tomato fruits, nitrate was decreased, whereas nitrite content was increased. In the changes of nitrate and ascorbic acid content in tomato fruits, nitrate content was decreased but that of ascorbic acid was increased slightly. In the changes of nitrite and ascorbic acid content in tomato fruits, nitrite content was increased and that of ascorbic acid was slightly increased too.

국산 무기 섬유계 단열재에 관한 연구

이종민,신현택,양중식 연세대학교 산업기술연구소 1980 논문집 Vol.12 No.2

Thermal characteristics and the related physical properties of various domestic fibrous inorganic products were investigated and the results are as follows: 1) Quality of the domestic fiber glass and the products meet the standards designated under KS, JIS and ASTM, and the products showed the fiber diameter of 4-15μ, the density of 0,004-0.07g/㎤ and the thermal conductivity of 0.027-0.049kcal/m hr℃. 2) Insulating characteristics of the glass fiber products are closely related with the diameter of the glass fiber and the density of the products, are increased with smaller fiber diameter and higher density of the products, and showed the thermal conductivity mostly lower than 0.035kcal/m hr℃ at 20℃ (Mean temp.) 3) Domestic mineral fiber showed its fiber diameter of 5-11μ and the thermal conductivity of 0.025-0.37kcal/m hr ℃ at 20℃ (Mean temp.)

U.S. and Antidumping Procedure

Joong Sik Shin 한국법학원 1990 저스티스 Vol.23 No.2

일측 태아기형을 동반한 쌍태임신

신중식(Joong Sik Shin),권소영(So Young Kwon),유중배(Jung Bae Yoo) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.4

Objective : To evaluate of the perinatal outcome of twin gestations complicated by a single anomalous fetus. Methods : The study included all patients with twin gestations diagnosed with a major fetal anomaly in one fetus in the second trimester during 1997-2000. Twins with anomalies in both fetuses and minor anomalies were excluded. From a total of 717 twin deliveries, there were 24 twin pregnancies with single anomalous fetus observed in Department of Obstetrics and Gynecology, CHA Hospital. Outcomes assessed included gestational age at diagnosis and delivery, antenatal complications, type of anomalies and perinatal mortality rate. Results : The incidence of single anomalous fetus with twin pregnancies was 3.3% in the study population. There were 24 twin pregnancies with one anomalous fetus, and their median gestational age at delivery was 35+3 weeks (range 27-39). The incidence of preterm delivery was 54.2% (13/24) and growth restriction and respiratory distress syndrome of the normal sibling were 12.5% (8/24) and 8.3% (2/24), respectively. Eight cases (33.3%) of preterm deliveries, 3 cases (12.5%) of severe preeclampsia were noted and 2 cases (8.3%) of the pregnancies were complicated with both conditions. Regarding the type of anomalies, chromosomal anomalies and central nervous system (CNS) anomalies were the most common with 5 cases (20.8%) each. Perinatal outcomes of the normal twin and the anomalous twin were compared. There were 2 cases (8.3%) of neonatal death in the normal twin compared with 9 cases (37.5%) of intrauterine death, 9 cases (37.5%) of neonatal death in the abnormal twin. Conclusion : Our study shows that the presence of a major anomaly in one fetus in a twin gestation significantly increased the risk of preterm delivery and risk of intrauterine fetal death and neonatal death rate in anomalous fetus. This information may provide useful information for counseling patients about their options when faced in dilemma.

자연적으로 임신된 쌍둥이 임신에서 단일융모막성이 주산기 결과에 주는 영향

신중식 ( Joong Sik Shin ),양재혁 ( Jae Hyug Yang ),류현미 ( Hyun Mee Ryu ),김문영 ( Moon Young Kim ),한정열 ( Jung Yeol Han ),안현경 ( Hyun Kyong Ahn ),정진훈 ( Jin Hoon Chung ),임하정 ( Ha Jung Lim ),김주오 ( Joo Oh Kim ),최준식 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.12

Objective : The Purpose of this study was to evaluate monochorionicity as a risk factor for adverse perinatal outcomes in spontaneously conceived twins. Methods : Using an established database, the study included pregnant women with spontaneously conceive

The influence of monochorionicity on the perinatal outcomes in spontaneously conceived twins

신중식 ( Joong Sik Shin ),( Jae Hyug Yang ),( Hyun Mee Ryu ),( Moon Young Kim ),( Jung Yeol Han ),( Hyun Kyong Ahn ),( Jin Hoon Chung ),( Ha Jung Lim ),( June Seek Choi ),( Joo Oh Kim ),( Su Hyun Park ) 대한산부인과학회 2004 대한산부인과학회 학술대회 Vol.90 No.-

한국인에서 Factor IX 유전인자와 연관된 다형현상

신중식(Joong Sik Shin),정성로(Sung Ro Jung),손일표(Il Pyo Son),조율희(Yool Hee Jo) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.11

Objective : Linkage analysis is a very useful method for prenatal diagnosis of Hemophilia B, especially when a mutation was not identified. Seven polymorphic markers were studied in Korean populations to evaluate the efficiency for prenatal and carrier diagnosis. Methods : Subjects of this study was 100 healthy Korean women (200 X-chromosomes). Polymerase chain reacton-restriction fragment length polymorphism (PCR-RFLP) method was used to detect SalI, MseI, NruI, DdeI, XmnI, TaqI and HhaI polymorphisms. Results : SalI (-) allele showed the frequency of 0.355 and SalI(+) allele 0.645. MseI(-) allele was 0.645 in frequency and MseI(+) allele was 0.355. SalI and MseI polymorphisms were in complete linkage disequilibrium. And no increase was expected in overall heterozygosity with these two polymorphisms. NruI(-) allele frequency was 0.855 and NruI(+) was 0.145. There was no polymorphism of DdeI, XmnI and TaqI marker systems in Korean population. In HhaI polymorphism, allele frequencies were estimated that HhaI(-) is 0.82 and HhaI(+) is 0.18. Conclusion : Only SalI, NruI and HhaI polymorphisms are useful for the diagnosis of hemophilia B in Korean population. Expected heterozygosity for above 3 poylmorphic markers was estimated to be 0.723, and 71 of 100 female subjects were heterozygous for at least one marker system. Korean population showed relatively low extent of polymorphisms compared to Caucasians, Blacks and Japanese. For the effective prenatal diagnosis of hemophilia B with linkage analysis, other polymorphic markers should be evaluated.

일측 태아사망이 동반된 쌍태임신의 연구

신중식 ( Joong Sik Shin ),이은경 ( Eun Kyung Lee ),유중배 ( Jung Bae Yoo ) 대한주산의학회 2001 Perinatology Vol.12 No.2

임신 초기 정상임신과 유산에서 혈청 CA 125 농도와의 관계

신중식 ( Joong Sik Shin ),김태진 ( Tae Jin Kim ),김용민 ( Yong Min Kim ) 대한주산의학회 2003 Perinatology Vol.14 No.3

목적: 본 연구는 임신 제 1삼분기에 혈청 내 CA 125 수치가 갑자기 증가하는 경우 자연유산의 가능성이 높았다는 이전의 연구를 바탕으로 시작되었다. 이를 위하여 계류유산, 절박유산, 정상 임신부의 혈청 CA 125를 측정하였고 예후 인자로 가능한가를 분석하였다. 이 연구의 목적은 CA 125수치를 임신초기에 전향적으로 비교 분석하여 자연유산을 예측할 수 있는 검사법으로 가능한지를 판단하고 기초 자료로 이용하고자 시도 되었다. 연구 방법: 2001년 3월부터 2001년 9월까지 강남 차병원 산부인과 외래를 방문한 133명의 초기 임신부를 대상으로 하였으며 이 중 58명은 계류유산, 45명은 절박유산, 나머지 30명은 이전에 자궁내막증이나 난소의 종양이 없었던 정상 임신부였다. 이들의 임신 주수는 모두 6주에서 12주 사이였으며 모든 대상은 초음파로 확인하였고 각각의 대상에서 혈청내 CA 125를 검사 하였다. 결과: 각 연구군의 CA 125 평균은 계류유산이 72.9±102.0IU/ml였고, 절박유산은 46.6±37.9IU/ml였으며 정상임신부는 63.4±61.2IU/ml였다. 각 연구군 간에는 통계학적으로 큰 의미가 없었다. 결론: 본 연구 결과 혈청 CA 125 수치는 임신 초기에 자연 유산을 예측하는 예후인자로써 큰 의미가 없었으며 계류유산, 절박유산, 정상임신을 구별하는데도 큰 역할을 하지 못 하였다. Objective: The study was carried out to assess whether a sudden rise in the serum CA 125 level might predict spontaneous abortion in the first trimester. In the process, we assessed the clinical value of maternal CA 125 in patients with missed abortion and evaluate the prognostic significance of CA 125 in early normal pregnancies, threatened abortions. The purpose of this study was to prospectively compare serum CA 125 levels among women who abort in the first trimester, who experience threateneda bortion and who go through normal pregnancy. Methods: Between March 2001 and September 2001, a total of 133 patients were observed in the Department of Obstetrics and Gynecology at CHA Hospital. Fifty-eight with missed abortions, forty-five with threatened abortions and thirty normal pregnancies (no history of endometriosis or ovarian mass) were evaluated during gestational age 6 to 12 weeks and maternal serum samples were collected. All patients were sonographically assessed and CA 125 values were compared. Results: There was no statistically significant difference in the CA 125 levels between the spontaneous aborted patients and the patients without abortion: missed abortion, 72.9±102.0IU/ml (range 7.3-487.6); threatened abortion, 46.6±37.9IU/ml (range 13.9-206.1); normal pregnancy, 63.4±61.2IU/ml (range 13.8-62.8). Conclusion: Our study shows that serum CA 125 levels are not predictive of spontaneous abortion in the first trimester and failed to discriminate among missed abortions, threatened abortions, and normal pregnancies.