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임윤규,이두식,박전홍,양기천,김승호,김공식,현관종,김우택,이영순 濟州大學校 農科大學 動物科學硏究所 1993 動物科學論叢 Vol.8 No.1
Enzyme-linked Immuno sorbent Assay (ELISA) for the serological diagnosis oi Bruceiia abortus was developed and compared with plate aggluhnation test Cell wall antigen was extracted from Brucella abortus 1119-3 by sonicabon and with a sodium deoxychlate solution Optimum protein concentra tion of coating antigen 0.4㎍/100㎕ protein on each microtiter plate well. Horse radish peroxidase(HRP) labled protein-G was used as a tracer of reacted antibodies ELISA confirmed the agreeable results of 40 rases out of 43 cases by plate aggulutination test ELISA diagnosed positive cases (10 out of 12) and negatiw cases (1 out of 12) with dubious sera by plate agglutination test From this results EL ISA could be used for the early diagnostic tools of Brucellosis in cattle.
흰쥐 척수 손상후 Parvalbumin과 Calbindin D-28K 함유신경세포에 관한 면역세포화학적 연구
김종중,정윤영,임유택,박상수,박영란,김현곤,문정석 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2
Background and Objectives: This study was done to compared the distribution of the two calcium-binding proteins immunoreactive neurons, parvalbumin immunoreactiv (PV-IR) and calbindin D-28K immunoreactive (CB-IR) neurons in the spinal cord after transection. Materials and Methods: Twenty rats were divided into 3 groups (control, complete spinal cord injury (SCI), and right and left spinal cord hemisection). SCI was produced by cutting the spinal cord use blades 11 with scalpel handles. Results: In this experiment, CB-IR neurons were mainly found in many pyramidal cells distributed in the brain stem and spinal cord of rats. PV-IR Neurons were demonstrated in all lamina of the gray matter of the spinal cord. These immunoreactive cells had the highest density in the layer I and II of dorsal horn and several nuclei of the ventral horn of the all the segments of the spinal cord. CB-IR neuropil labeling was strongly noted in all the segments of the spinal cord. In contrast PV-IR neurons were different in distribution, size and morphology in the spinal cord. The number of PV-IR neurons were greater than in the spinal cord compared with the CB-IR neurons. CB-IR and PV-IR somata were round, oval, spindle and polygonal in shape, and were unipolar, bipolar, multipolar and horizontal in types. The diameters of the somata of the PV-IR and CB-IR neurons were 40-50 ㎛, respectively. Also dendrites of PV-IR and CB-IR neurons were densely arrayed in network.
소아의 굴염에서 생리 식염수 비 세척과 충혈 제거제의 사용에 대한 전향적 무작위 개방 시험
윤종서 ( Jong Seo Yoon ),조연수 ( Yeon Soo Cho ),김민성 ( Min Sung Kim ),전윤홍 ( Yoon Hong Chun ),김현희 ( Yeon Soo Cho ),김진택 ( Jin Tack Kim ),이준성 ( Joon Sung Lee ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2010 소아알레르기 및 호흡기학회지 Vol.20 No.4
목적: 소아 굴염은 치료방법에 대해 논란이 많다. 일반적으로는 항생제를 사용하는 것이 가장 기본적인 치료로 알려져 있다. 부가적인 치료로서, 식염수로 비강을 세척하는 방법 그리고 충혈 제거제의 사용이 이루어지고 있으나, 이러한 추가적인 치료들의 효과에 대하여는 아직 명확하게 밝혀져 있지 않다. 이에 저자는 굴염의 치료에 있어서, 항생제를 기본적으로 사용하고, 이에 추가로 생리 식염수로 비강을 세척하는 방법 또는 충혈 제거제 복용, 또는 이 두 가지를 함께 추가하는 치료를 시도해서 각 치료 방법의 성과를 비교하고자 하였다. 방법: 소아 호흡기질환 클리닉에 내원한 굴염 환자를 대상으로 분석하였다. 무작위로 다음의 4가지 치료법 중 한 가지의 치료법을 적용하였다. 그룹 1은 고용량 아목시실린만 사용, 그룹 2는 고용량 아목시실린에 추가로 생리 식염수로 비강 세척을 사용, 그룹 3은 고용량 아목시실린에 추가로 충혈 제거제를 사용, 그룹 4는 고용량 아목시실린에 추가로 생리 식염수 비강 세척과 충혈 제거제를 모두 사용한 경우로 하였다. 치료에 대한 반응을 급성 및 아급성 굴염의 경우은 치료 시작 후 최소 4일 후, 만성 굴염의 경우는 치료 시작 후 최소 7일 후에 평가하였다. 결과: 4개의 치료법 간의 치료에 대한 반응을 비교했을 때, 각 그룹간에 차이가 없었다. 환자가 화농성 콧물, 코 막힘, 후비루, 굴 사진에서 특정한 소견, 그리고 아데노이드 비대증을 가지고 있는가에 따라 더 좋은 반응을 보이는 치료 방법은 없었다. 결론: 소아 굴염 환자 치료 시에 고용량 아목시실린에 추가적으로 생리 식염수 비 세척이나 충혈 제거제의 경구 사용은 환자의 증상개선에 있어서 추가적인 이득이 없었다. Purpose: The management of sinusitis in children is controversial. Antibiotic is known as the most essential management. Despite nasal irrigation and nasal decongestant have been used as adjunctive treatments of sinusitis, it is still unclear whether these are effective on sinusitis. Therefore, we used antibiotics with either nasal irrigation and an oral nasal decongestant and tried to estimate the outcome of each case. Methods: This study was conducted with sinusitis patients who visited our pediatric respiratory disease clinic. They were randomized into 4 groups: Group 1 were treated with a high dose of amoxicillin only; Group 2 were treated with nasal irrigation and a high dose of amoxicillin; Group 3 were treated with a nasal decongestant and a high dose of amoxicillin; and Group 4 were treated with nasal irrigation, a oral nasal decongestant, and a high dose of amoxicillin. Responses to treatment were estimated more than 4 days after the beginning of the therapy in acute or subacute sinusitis, and more than 7 days chronic sinusitis. Results: The responses to the treatments the 4 groups were not comparable. A favorable therapy was not found, regardless of whether a patient had suppurative rhinorrhea, nasal stuffness, typical findings of PNS plain radiograph, or adenoid hypertrophy. Conclusion: The use of nasal irrigation or a oral nasal decongestant as an additional therapy to antibiotics for the symptoms of pediatric sinusitis showed no additional effects on sinusitis. [Pediatr Allergy Respir Dis(Korea) 2010;20:232-237]
A Study on the Electrodeposition of Uranium Using a Liquid Cadmium Cathode at 440℃ and 500℃
Jong-Ho Yoon,Si-Hyung Kim,Gha-Young Kim,Tack-Jin Kim,Do-Hee Ahn,Seungwoo Paek 한국방사성폐기물학회 2013 방사성폐기물학회지 Vol.11 No.3
파이로프로세싱에서 전해제련은 액체카드뮴음극(liquid cadmium cathode, LCC)을 이용하여 우라늄과 초우라늄원소(TRU)를 동시에 회수하는 공정이다. 액체카드뮴음극의 표면에 전착된 우라늄이 카드뮴 중의 우라늄 용해도(2.35wt%)를 초과하여 전착되면, 표면적이 큰 수지상 우라늄을 형성하여 액체카드뮴 내부로 가라앉지 않고 이 수지상 우라늄 자체가 고체전극으로 작용한다. 따라서 본 연구에서는 Cd-U 상태도를 바탕으로 α상 우라늄(수지상 우라늄)이 안정하게 존재하는 500℃와 카드뮴과 우라늄간 금속간 화합물(intermetallic compound)이 형성되는 440℃의 두 가지의 온도 조건에서 전착실험을 하였다. 440℃에서 정전류법으로 전착한 경우, 우라늄은 수지상이 아닌 알갱이 형태로 전착되었고 액체카드뮴음극의 도가니 밖으로 자라나지 않은 채 카드뮴 풀 중앙을 중심으로 일정하게 적층되었다. XRD 분석을 통해 이러한 전착물이 UCd11이라는 금속간 화합물이라는 것을 알 수 있었다. UCd11은 카드뮴보다 비중이 커서 전착 중에 액체카드뮴 내부로 침전되므로 교반기를 사용하지 않고도 우라늄과 초우라늄원소를 동시에 회수할 수 있을 것으로 판단된다.
Fabrication of a Cement Waste Form for Final Disposal of Spent Ion Exchange Resins
Yoon-Do Oh,Jong-Sik Shon,Hee-Chul Eun,Chang-Ho Park,Tae-Su Song,Hae-Min Park,Dong-Su Kim,Tack-Jin Kim,Sung-Bin Park 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Spent ion exchange resins have been generated during the operation of nuclear facilities. These resins include radioactive nuclides. It is needed to fabricate them into a stable form for final disposal. Cement solidification process is a useful method for the fabrication of them into a waste form for final disposal. In this study, proper conditions for the fabrication of them into a stable waste form were determined using the cement solidification process. In-drum waste forms were then produced at the conditions, where the stability of representative samples was evaluated for final disposal. The samples were satisfied to the Waste Acceptance Criteria for low and intermediate level radioactive waste disposal sites. This result can be utilized to derive optimal conditions for the fabrication of spent ion exchange resins into a final disposal form.
이종국,이윤호,권성택 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.6
Until recent years, the incidence of the burn patients has been still high. Most of them should be received secondary reconstructive surgery even after the completion of primary treatment of acute burn because of several reasons. As the industry and the traffics develope, the occurrence of the accidents becomes much more frequent. As the complications or sequalae of industrial or burn accidents, the linear scar contractures used to be developed frequently. So, we need another method of treatment for this kind of unaesthetic and nonfunctional results. In fact, until recent days, release and skin graft or local flap transposition as like z-plasty and the complex of these methods have been used to treat linear scar contractures. But, in the case of skin grafting, as the skin grafted patient grows, the growth of skin grafted area cannot catch up the growth of surrounding normal area. In some cases, we need another secondary skin graft procedure after completion of patient's growth. In the case of flap method, we often found difficulties in designing the flap due to surrounding scar tissue or flap necrosis due to poor blood supply. For the purpose of solving above problems, Grishkevich developed the concept of trapezeplasty and Cooper developed multiple Y - V plasty to release linear burn scar contracture. But though these methods have been widely used, there are some limitations of flap availability. Therefore, we tried to modify and to apply various designs of multiple Y-V plasty technique to the variable clinical problematic cases. So, are found this our liberally designed and variable sized multiple Y - V plasty technique is more simple, flexilbe(it can be changed during operative porcedures) and reliable. It is due to that the flap transposition was done only by direct advancement without endangering the vascular circulation of the flap. Conclusively, we would like to say that this method can be used in more variable scar contracuture cases.
소아에서 굴곡성 기관지 내시경술을 이용한 무기폐 치료의 유용성
전윤홍 ( Yoon Hong Chun ),강성실 ( Sung Shil Kang ),방경원 ( Kyung Won Bang ),김환수 ( Hwan Soo Kim ),이의경 ( Eu Kyoung Lee ),윤종서 ( Jong Seo Yoon ),김현희 ( Hyun Hee Kim ),김진택 ( Jin Tack Kim ),이준성 ( Joon Sung Lee ) 대한소아알레르기호흡기학회 1991 소아알레르기 및 호흡기학회지 Vol.1 No.3
Purpose: This study was to evaluate the effect of flexible bronchoscopy for the treatment of secondary atelectasis of children following respiratory infection. Methods: The medical records for a total of 19 cases of flexible bronchoscopy were reviewed retrospectively, which were performed for the treatment of secondary atelectasis at the Department of Pediatrics of the Catholic University of Korea Seoul St. Mary’s Hospital from April 2007 to January 2013. Results: A total of 18 patients (11 males and 7 females) were involved in the study. The range of age was 4 months to 15 years old. The causative underlying diseases were 17 cases of pneumonia, 1 case of bronchiolitis and 1 case of bronchial asthma. The most common location of atelectasis was right middle lobe and right middle lobe with left lower lobe was next. Bronchoscopy revealed inflammatory changes in 12 cases (63.2%) such as mucus plug (n=4), profuse secretion (n=4), mucosal edema (n=3), and bronchial narrowing (n=1), although 7 cases (36.8%) showed normal airway. Other additional findings were bronchomalacia, tracheomalacia, and bronchial tree abnormality. Seven out of 19 cases who received therapeutic intervention had complete or partial reexpansion of their atelectasis. Cases who occurred atelectasis within 6 weeks showed significantly higher improvement than cases occurred after 6 weeks (70% vs. 11.1%, P=0.019). Complications including seizure, fever, hypoxia, mucous bleeding, and hypotension were observed in 6 cases. Conclusion: Flexible bronchoscopy revealed to be effective and safe treatment modality in treatment of secondary atelectasis of children. Timely therapeutic intervention in pediatric patients should be considered. (Allergy Asthma Respir Dis 2013;1:274-279)